Abstract:
PROBLEM TO BE SOLVED: To provide an immunostimulant, to provide such a vaccine composition that the immunostimulant is included in particles like microspheres or liposomes, to provide a treatment method using the immunostimulant, and to provide a method for producing the vaccine.SOLUTION: A polycationic carbohydrate such as chitosan or a pharmaceutically acceptable derivative thereof is to be used as the immunostimulant.
Abstract:
Compositions of reagents are formed by forming empty liposomes, mixing the thus-formed liposomes with a sugar solution and a regent, then drying the mixture. The compositions will generally contain less than 10% w/v sucrose. Using this procedure small liposomes are formed with high entrapment efficiency. The process is useful in the production of pharmaceuticals.
Abstract:
PROBLEM TO BE SOLVED: To provide a surface-coated substrate particularly with an oil repellent and water-repellent surface. SOLUTION: The oil repellent and water-repellent substrate has the surface coated with a polymer layer performed by plasma processing of a monomer compound in formula (I) under conditions where polymerization is carried out under the reaction of double bond of the monomer compound in formula (I), wherein R 1 , R 2 , and R 3 are independently selected from hydrogen, alkyl, haloalkyl or aryl that may be substituted with halogen; provided that at least one of R 1 , R 2 , and R 3 is hydrogen, and R 4 is a group X-R 5 wherein R 5 is an alkyl or haloalkyl group and X is a bond; a group of formula -C(O)O(CH 2 ) n Y- wherein n is an integer of 1 to 10, and Y is a bond or a sulfonamide group; or a group -(O) p R 6 (O) q (CH 2 ) t - wherein R 6 is aryl that may be optionally substituted with halogen, p is 0 or 1, q is 0 or 1, and t is 0 or an integer of 1 to 10, provided that where q is 1, t is other than 0. COPYRIGHT: (C)2010,JPO&INPIT