公开(公告)号：EP0659086B1

公开(公告)日：1998-11-11

申请号：EP93918846.2

申请日：1993-09-03

Applicant: The University of Saskatchewan

Inventor： ALLAN, Brenda J. ,  POTTER, Andrew A.

IPC: A61K39/108

CPC classification number: C07K14/245 ,  A61K39/00

Abstract: Vaccines are provided for vaccinating an animal against pathogenic bacteria, including (E. coli). The invention also encompasses methods of preparing and methods of use of vaccine strains and compositions that result from or are used in these methods.

公开(公告)号：EP0527724B1

公开(公告)日：1997-08-27

申请号：EP90906831.4

申请日：1990-05-25

Applicant: The University of Saskatchewan

Inventor： ACRES, Stephen, D. ,  BARIUK, Lorne, A. ,  POTTER, Andrew, A. ,  LAWMAN, Michael, J., P.

IPC: A61K39/102 ,  C12N15/31

CPC classification number: A61K39/102 ,  A61K39/00 ,  C07K14/285

Abstract: New proteins and subunit antigens from P. haemolytica for use in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The subunit antigens include immunogenic amino acid sequences of P. haemolytica fimbrial protein, P. haemolytica plasmin receptor protein, and P. haemolytica 50 K outer membrane protein and P. haemolytica leukotoxin. The antigens can be used in a vaccine composition, either alone or in combination. Also disclosed are methods of vaccination as well as methods of making the subunit antigens employed in the vaccines.

公开(公告)号：EP0711148A1

公开(公告)日：1996-05-15

申请号：EP94922214.0

申请日：1994-07-28

Applicant: The University of Saskatchewan

Inventor： FOLDVARI, Marianna

IPC: A61K8 ,  A61K9 ,  A61Q19

CPC classification number: A61K8/14 ,  A61K9/127 ,  A61K9/1277 ,  A61Q19/00

Abstract: A biphasic multilamellar lipid vesicle comprising a plurality of spaced apart lipid bilayers that include a liposome-forming component and optionally a biologically active agent entrapped within the lipid bilayers. The lipid vesicle also comprises peripheral aqueous solution compartments formed between the lipid bilayers and a central lipophilic core compartment substantially at the center of the multilamellar lipid vesicle.

公开(公告)号：EP0660723A1

公开(公告)日：1995-07-05

申请号：EP92902950.0

申请日：1992-01-29

Applicant: The University of Saskatchewan

Inventor： REDMOND, Mark, J. ,  CAMPOS, Manuel, Dr.

IPC: A61K9 ,  A61K38 ,  A61K47 ,  A61P35 ,  A61P37 ,  C07K14

CPC classification number: A61K9/5184 ,  A61K38/2013 ,  A61K38/217 ,  A61K47/6901 ,  C07K14/005 ,  C12N2710/14143 ,  C12N2720/12322

Abstract: Compositions and methods for preparing and delivering encapsulated biologically active agents to specific cell types are disclosed. Substances can be encapsulated in the VP6 inner capsid protein of rotavirus and delivered to selected cells, tissues and organs. Targeting agents can be linked to the surface of the VP6 sphere so that appropriate agents can be delivered to preselected cells and tissue types.

公开(公告)号：EP0652957A1

公开(公告)日：1995-05-17

申请号：EP91917981.0

申请日：1991-10-24

Applicant: The University of Saskatchewan

Inventor： REDMOND, Mark, J. ,  IJAZ, Mohammed, Khalid ,  PARKER, Michael, D.

IPC: A61K39 ,  A61P31 ,  C07K14 ,  C12N7 ,  C12N15 ,  C12P21 ,  C12R1

CPC classification number: C07K14/005 ,  A61K39/00 ,  C12N7/00 ,  C12N2720/12322 ,  C12N2720/12323 ,  Y10S530/826

公开(公告)号：EP0478609B1

公开(公告)日：1994-09-07

申请号：EP90909119.1

申请日：1990-06-21

Applicant: The University of Saskatchewan

Inventor： LAARVELD, Bernard ,  KIRKWOOD, Roy Neville ,  THACKER, Philip, Alfred ,  SORDILLO, Lorraine, M. ,  REDMOND, Mark

IPC: A61K37/43 ,  A61K47/48

CPC classification number: C07K16/26 ,  A61K39/0005 ,  A61K2039/55505 ,  A61K2039/6081 ,  C07K2317/34

Abstract: Compositions and methods for modulating SRIF activity as well as enhancing the reproductive performance and immunological function in vertebrates are disclosed. Compositions containing SRIF-related peptides or antibodies thereto can be administered to animals to modulate endogenous SRIF-like activity. The SRIF-related peptides can be linked to a carrier such as ovalbumin, and administered in an Al(OH)3 adjuvant, to enhance the immunogenicity of the SRIF-related peptides.

公开(公告)号：EP0235391A3

公开(公告)日：1988-05-04

申请号：EP86117981

申请日：1986-12-23

Applicant: The University of Saskatchewan

Inventor： Sabara, Marta I. ,  Frenchick, Patrick J. ,  Potter, Andrew A. ,  Ijaz, Mohammad K. ,  Gilchrist, James E.

IPC: C07K13/00 ,  A61K39/15 ,  A61K39/385

CPC classification number: C07K14/005 ,  A61K39/385 ,  A61K2039/6081 ,  C12N2720/12322

Abstract: Synthetic peptides corresponding to antigenic determinants of three major neutralizing proteins of bovine rotavirus are disclosed. These peptides are useful in stimulating immunity and interfering with viral infectivity and can be used as vaccines and in other ways for treatment, prevention or diagnosis of rotavirus infections of birds and animals including man.

公开(公告)号：EP0235391A2

公开(公告)日：1987-09-09

申请号：EP86117981.0

申请日：1986-12-23

Applicant: The University of Saskatchewan

Inventor： Sabara, Marta I. ,  Frenchick, Patrick J. ,  Potter, Andrew A. ,  Ijaz, Mohammad K. ,  Gilchrist, James E.

IPC: C07K13/00 ,  A61K39/15 ,  A61K39/385

CPC classification number: C07K14/005 ,  A61K39/385 ,  A61K2039/6081 ,  C12N2720/12322

Abstract: Synthetic peptides corresponding to antigenic determinants of three major neutralizing proteins of bovine rotavirus are disclosed. These peptides are useful in stimulating immunity and interfering with viral infectivity and can be used as vaccines and in other ways for treatment, prevention or diagnosis of rotavirus infections of birds and animals including man.

Abstract translation: 公开了对应于牛轮状病毒的三种主要中和蛋白质的抗原决定簇的合成肽。 这些肽可用于刺激免疫和干扰病毒感染性，并且可以用作疫苗，并以其他方式用于治疗，预防或诊断包括人在内的鸟类和动物的轮状病毒感染。

公开(公告)号：EP4138894A1

公开(公告)日：2023-03-01

申请号：EP21793327.4

申请日：2021-04-19

Applicant: The University of Saskatchewan ,  The University of British Columbia

Inventor： FACCIUOLO, Antonio ,  GRIEBEL, Philip ,  GERDTS, Volker ,  POTTER, Andrew ,  RAWLYK, Neil ,  CHEN, Jeffrey ,  PASTURAL, Elodie ,  BAINS, Manjeet ,  TRIMBLE, Michael ,  LEE, Amy ,  HANCOCK, Robert

IPC: A61K39/04 ,  A61P31/04 ,  A61P31/06 ,  A61P37/04 ,  G01N33/564

公开(公告)号：EP1094837B1

公开(公告)日：2009-12-23

申请号：EP99932831.3

申请日：1999-06-28

Applicant: MERIAL ,  The Queen's University of Belfast ,  The University of Saskatchewan

Inventor： ALLAN, Gordon, Moore ,  MEEHAN, Brian, Martin ,  ELLIS, John, Albert ,  KRAKOWKA, George, Steven ,  AUDONNET, Jean-Christophe, Francis ,  MCNEILLY, Francis

IPC: A61K39/395 ,  C07K14/01 ,  C12N7/00 ,  C12N15/86

CPC classification number: C07K14/005 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  A61K2039/70 ,  C12N7/00 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/14322 ,  C12N2750/14334 ,  Y10S424/815 ,  Y10S435/81