公开(公告)号：US20100143911A1

公开(公告)日：2010-06-10

申请号：US12519791

申请日：2007-12-21

Applicant: Sang Yup Lee ,  Hawoong Jeong ,  Tae Yong Kim ,  Pan-Jun Kim ,  Kwang Ho Lee

Inventor： Sang Yup Lee ,  Hawoong Jeong ,  Tae Yong Kim ,  Pan-Jun Kim ,  Kwang Ho Lee

IPC: C12Q1/68 ,  C12Q1/02 ,  C12N15/74 ,  C12N1/21

CPC classification number: C12Q1/18 ,  G01N33/5038

Abstract: The present invention disclosed is a method for screening metabolites essential for the growth of microorganism using metabolic flux analysis. More specifically, the present invention relates to the method for screening metabolites essential for the growth of microorganism, by selecting a target microorganism, constructing a metabolic network model of the selected microorganism, inactivating the consumption reaction of each of metabolites in the constructed metabolic network model, analyzing the metabolic flux of the metabolites to select metabolites essential for the growth of the microorganism, and confirming the selected metabolites using the utilization of each of the metabolites, defined as flux sum (Φ). According to the present invention, metabolites essential for the growth of microorganism, and genes involved in the essential metabolites, can be screened in a convenient manner, and drug-target genes against pathogenic microorganisms can be predicted by deleting genes associated with the metabolites screened according to the method.

Abstract translation: 所公开的本发明是使用代谢通量分析来筛选微生物生长所必需的代谢物的方法。 更具体地说，本发明涉及通过选择靶微生物，构建所选择的微生物的代谢网络模型，在构建的代谢网络模型中灭活各代谢物的消费反应来筛选微生物生长所必需的代谢物的方法 分析代谢物的代谢通量以选择微生物生长所必需的代谢物，并使用定义为通量和（Φ）的每种代谢物来确认所选择的代谢物。 根据本发明，可以以便利的方式筛选微生物生长所必需的代谢物和基本代谢物所涉及的基因，并且可以通过删除与代谢物相关的基因来预测针对病原微生物的药物靶基因 的方法。

公开(公告)号：US20100075632A1

公开(公告)日：2010-03-25

申请号：US12548224

申请日：2009-08-26

Applicant: Tae Yong KIM

Inventor： Tae Yong KIM

IPC: G06F11/00 ,  H04M1/66 ,  G06F3/048

CPC classification number: G06F21/56 ,  H04W12/00503 ,  H04W12/00508 ,  H04W12/1208

Abstract: A method of controlling a mobile terminal, and which includes detecting, via a controller, a suspicious attempt that may have been caused by a virus from the mobile terminal, shutting down the detected attempt, choosing one or more terminals that are associated with the mobile terminal, and notifying, via an alarm unit, said one or more chosen other terminals that the mobile terminal is infected.

Abstract translation: 一种控制移动终端的方法，其包括经由控制器检测可能由来自移动终端的病毒引起的可疑尝试，关闭所检测到的尝试，选择与移动终端相关联的一个或多个终端 终端，并且经由警报单元通知所述一个或多个所选择的其他终端，所述移动终端被感染。

公开(公告)号：US07682732B2

公开(公告)日：2010-03-23

申请号：US11166403

申请日：2005-06-23

Applicant: Tae-Yong Kim ,  Gun-Goo Lee ,  Yoon-Cheol Jeon

Inventor： Tae-Yong Kim ,  Gun-Goo Lee ,  Yoon-Cheol Jeon

IPC: H01M6/42 ,  H01M2/00

CPC classification number: B60L11/1874 ,  H01M2/0247 ,  H01M2/1061 ,  H01M2/1077 ,  H01M10/613 ,  H01M10/617 ,  H01M10/625 ,  H01M10/647 ,  H01M10/651 ,  H01M10/6566 ,  Y02T10/7005 ,  Y02T10/705

Abstract: A secondary battery module has a plurality of unit batteries adjacently spaced apart from each other. A barrier rib is disposed between adjacent unit batteries, the barrier rib having a plurality of protrusions.

Abstract translation: 二次电池模块具有彼此间隔开的多个单元电池。 隔壁设置在相邻的单元电池之间，隔壁具有多个突起。

公开(公告)号：US07651812B2

公开(公告)日：2010-01-26

申请号：US11362222

申请日：2006-02-27

Applicant: Tae-Yong Kim ,  Gun-Goo Lee ,  Yoon-Cheol Jeon

Inventor： Tae-Yong Kim ,  Gun-Goo Lee ,  Yoon-Cheol Jeon

IPC: H01M2/10

CPC classification number: H01M10/613 ,  H01M6/42 ,  H01M10/647 ,  H01M10/652 ,  H01M10/6557 ,  H01M10/6563 ,  H01M10/6566

Abstract: A rechargeable battery module includes a plurality of unit batteries disposed apart at predetermined intervals and barriers interposed therebetween. The barriers include a plurality of protrusions and a plurality of plates with at least one junction portion. The junction portion on one plate is fixed to another plate opposing the one plate.

Abstract translation: 可再充电电池模块包括以预定间隔分开设置的多个单元电池和插入其间的屏障。 阻挡层包括多个突起和具有至少一个接合部分的多个板。 一个板上的接合部固定在与一个板相对的另一个板上。

公开(公告)号：US07605562B2

公开(公告)日：2009-10-20

申请号：US11159191

申请日：2005-06-23

Applicant: Tae-Yong Kim

Inventor： Tae-Yong Kim

IPC: H02J7/00

CPC classification number: H01M2/206 ,  H01M2/1077 ,  H01M2/12 ,  H01M10/0481 ,  H01M10/613 ,  H01M10/647 ,  H01M10/6557 ,  H01M10/6566

Abstract: A rechargeable battery module that exhibits superior temperature control and has a minimized size through an efficient arrangement of unit batteries is provided. The rechargeable battery module has a plurality of unit batteries that are arranged at constant intervals and a housing that holds the unit batteries and in which air for controlling a temperature of each of the unit batteries flows. The unit batteries are divided into two battery columns that are provided on either side of a central structure such that terminals of the unit batteries in different columns face each other.

Abstract translation: 提供了通过单元电池的有效布置显示出优异的温度控制并且具有最小尺寸的可再充电电池模块。 可再充电电池模块具有以恒定间隔布置的多个单位电池和保持单元电池的壳体，并且其中用于控制每个单元电池的温度的空气流动。 单元电池被分成两个电池列，其设置在中央结构的两侧，使得不同列中的单元电池的端子彼此面对。

公开(公告)号：US20090215048A1

公开(公告)日：2009-08-27

申请号：US11994330

申请日：2005-10-14

Applicant: Sang Yup Lee ,  Tae Yong Kim ,  Dong Yup Lee

Inventor： Sang Yup Lee ,  Tae Yong Kim ,  Dong Yup Lee

IPC: C12Q1/68 ,  G06F19/00 ,  C12N15/00 ,  C12N15/74 ,  C12P7/46

CPC classification number: G16B5/00 ,  G16B20/00

Abstract: The present invention relates to an in silico method for improving an organism on the basis of the flux sum (φ) of metabolites, and more particularly to a method for screening key metabolites that increase the production yield of a useful substance, the method comprising defining the metabolite utilization of an organism for producing a useful substance as flux sum and perturbing the flux sum, as well as a method for improving an organism producing a useful substance, the method comprising deleting and/or amplifying genes associated with the aforementioned screened key metabolites. According to the present invention, the correlation between specific metabolites and useful substance production can be exactly predicted, so that it is possible to develop an organism having increased useful substance production by introducing and/or amplifying and/or deleting genes expressing enzymes associated with the specific metabolites. In addition, it is also possible to increase the production of a useful substance by adding specific metabolites during culture.

Abstract translation: 本发明涉及一种基于代谢物的通量和（phi）改善生物体的计算机方法，更具体地涉及一种筛选提高有用物质产量的关键代谢物的方法，该方法包括定义 用于产生有用物质的生物体的代谢物利用作为助熔剂和扰乱通量和，以及改善产生有用物质的生物体的方法，所述方法包括删除和/或扩增与上述筛选的关键代谢物相关的基因 。 根据本发明，可以准确地预测特定代谢物和有用物质生产之间的相关性，从而可以通过引入和/或扩增和/或删除表达与...相关的酶的基因来开发具有增加的有用物质生产的生物体 特异性代谢物。 此外，还可以通过在培养期间加入特定的代谢物来增加有用物质的产生。

公开(公告)号：US07541770B2

公开(公告)日：2009-06-02

申请号：US11401410

申请日：2006-04-11

Applicant: Tae-Yong Kim ,  Hong-Sup Lim ,  Yoon-Cheol Jeon

Inventor： Tae-Yong Kim ,  Hong-Sup Lim ,  Yoon-Cheol Jeon

IPC: H01M10/46

CPC classification number: H01M2/1077 ,  H01M10/613 ,  H01M10/647 ,  H01M10/651 ,  H01M10/6556 ,  H01M10/6557 ,  H01M10/6563 ,  Y10T307/50

Abstract: A battery module includes a plurality of unit batteries disposed apart at intervals and a plurality of barriers interposed between the unit batteries. Each of the barriers includes a base supported on the unit battery and a plurality of protrusions extending from the base and contacting the unit battery. The protrusions are formed of an insulation material. In addition, the protrusions may be fixed onto the base in a staggered arrangement along columns and rows so that a certain angular arrangement between the alignment of protrusions is achieved, thereby maximizing cooling efficiency.

Abstract translation: 电池模块包括间隔开地设置的多个单元电池和插在单元电池之间的多个屏障。 每个屏障包括支撑在单元电池上的基座和从基座延伸并接触单元电池的多个突起。 突起由绝缘材料形成。 此外，突起可以沿列和列以交错布置固定到基座上，使得在突起的对准之间实现一定的角度布置，从而最大化冷却效率。

公开(公告)号：US20090075352A1

公开(公告)日：2009-03-19

申请号：US11722632

申请日：2005-05-23

Applicant: Sang Yup Lee ,  Tae Yong Kim ,  Dong Yup Lee ,  Sang Jun Lee

Inventor： Sang Yup Lee ,  Tae Yong Kim ,  Dong Yup Lee ,  Sang Jun Lee

IPC: C12P7/46 ,  G06G7/48 ,  C12N1/21

CPC classification number: C12P7/46 ,  C12N9/1205 ,  C12N15/1089

Abstract: The present invention is related to a method for improving a strain on the basis of in silico analysis, in which it compares the genomic information of a target strain for producing a useful substance to the genomic information of a strain overproducing the useful substance so as to primarily screen genes unnecessary for the overproduction of the useful substance, and then to secondarily screen genes to be deleted through performing simulation with metabolic flux analysis. According to the present invention, an improved strain can be effectively constructed by the metabolic and genetic engineering approach comprising comparatively analyzing the genomic information of a target strain for producing a useful substance and the genomic information of a strain producing a large amount of the useful substance to screen candidate genes and performing in silico simulation on the screened candidate genes to select a combination of genes to be deleted, which shows an improvement in the production of the useful substance. Accordingly, the time, effort and cost required for an actual wet test can be significantly reduced.

Abstract translation: 本发明涉及一种基于在计算机分析中改进菌株的方法，其中将用于产生有用物质的靶菌株的基因组信息与过量产生有用物质的菌株的基因组信息进行比较，以便 主要是用于过量生产有用物质的筛选基因，然后通过用代谢通量分析进行模拟来次要筛选待缺失的基因。 根据本发明，可以通过代谢和基因工程方法有效地构建改进的菌株，其包括比较分析用于产生有用物质的靶菌株的基因组信息和产生大量有用物质的菌株的基因组信息 筛选候选基因并在筛选的候选基因的计算机模拟中进行选择要缺失的基因的组合，其显示有用物质的生产的改进。 因此，可以显着降低实际湿测试所需的时间，精力和成本。

公开(公告)号：US20080063929A1

公开(公告)日：2008-03-13

申请号：US11852143

申请日：2007-09-07

Applicant: Sang-Won Byun ,  Tae-Yong Kim ,  Yoon-Cheol Jeon ,  Gun-Goo Lee

Inventor： Sang-Won Byun ,  Tae-Yong Kim ,  Yoon-Cheol Jeon ,  Gun-Goo Lee

IPC: H01M2/20

CPC classification number: H01M2/206 ,  H01M2/202 ,  H01M2/204

Abstract: A battery module includes a plurality of unit batteries, each unit battery having a terminal having a terminal contact portion. A electrically conductive adaptor connects the terminals of adjacent unit batteries, the electrically conductive adaptor having an adaptor contact surface. The terminal contact portion has a contact portion contact surface coupled to the adaptor contact surface. The contact portion contact surface and the adaptor contact surface are parallel to a longitudinal axis of the terminal.

Abstract translation: 电池模块包括多个单元电池，每个单元电池具有端子，具有端子接触部分。 导电适配器连接相邻单元电池的端子，导电适配器具有适配器接触表面。 端子接触部分具有联接到适配器接触表面的接触部分接触表面。 接触部分接触表面和适配器接触表面平行于端子的纵向轴线。

公开(公告)号：US20070285052A1

公开(公告)日：2007-12-13

申请号：US11808422

申请日：2007-06-08

Applicant: Yoon-Cheol Jeon ,  Tae-Yong Kim ,  Sang-Won Byun

Inventor： Yoon-Cheol Jeon ,  Tae-Yong Kim ,  Sang-Won Byun

IPC: H02J7/00

CPC classification number: H01M10/0413 ,  H01M10/0468 ,  H01M10/613 ,  H01M10/625 ,  H01M10/647 ,  H01M10/6551 ,  H01M10/6562

Abstract: A battery module is constructed with a plurality of unit batteries, and barrier ribs including bands mounted on each of the unit batteries and forming gaps to enable a heat conductive medium to circulate the unit batteries.

Abstract translation: 电池模块由多个单元电池和隔肋构成，包括安装在每个单元电池上的带，并形成间隙，以使得导热介质能够使单元电池循环。