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公开(公告)号：KR1020110000716A
公开(公告)日：2011-01-05
申请号：KR1020100117492
申请日：2010-11-24
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing herb extract for skin care or plasty is provided to promoter differentiation of mesenchymal stem cells to adipocytes. CONSTITUTION: A composition for promoting differentiation to adipocytes contains Cinnamomum cassia extract as an active ingredient. The composition increases fat tissue. The mesenchymal stem cells are human bone marrow stem cells.
Abstract translation: 目的：提供含有皮肤护理或整形草药提取物的组合物，以促进间充质干细胞向脂肪细胞的分化。 构成：促进脂肪细胞分化的组合物含有肉桂提取物作为活性成分。 组合物增加脂肪组织。 间充质干细胞是人类骨髓干细胞。
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公开(公告)号：KR1020100051286A
公开(公告)日：2010-05-17
申请号：KR1020080110377
申请日：2008-11-07
Applicant: (주)아모레퍼시픽
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/158 , G01N33/15 , G01N33/5008
Abstract: PURPOSE: A screening method of a skin improvement material is provided to effectively screen the skin improvement material capable of preventing skin ageing, maintaining skin moisture, and improving skin barrier function. CONSTITUTION: A screening method of a skin improvement material comprises the following steps: processing a candidate material to a skin cell; detecting an expression amount change of MAP17(membrane-associated protein 17kd); and selecting the candidate material which induces the change of the expression amount as the skin improvement material. The skin cell is a skin keratinocyte.
Abstract translation: 目的：提供皮肤改善材料的筛选方法，以有效地筛选能够防止皮肤老化，保持皮肤水分和改善皮肤屏障功能的皮肤改善材料。 构成：皮肤改善材料的筛选方法包括以下步骤：将候选材料加工到皮肤细胞; 检测MAP17（膜相关蛋白17kd）的表达量变化; 并选择引起表达量变化的候选材料作为皮肤改善材料。 皮肤细胞是皮肤角质形成细胞。
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公开(公告)号：KR1020100025070A
公开(公告)日：2010-03-09
申请号：KR1020080083683
申请日：2008-08-27
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition for suppressing differentiation and growth of adipocytes is provided to treat or prevent circulatory system disease or ischemic heart disease. CONSTITUTION: A composition for suppressing differentiation or growth of adipocytes contains 0.00001 to 15 weight% of chemerin. The adipocyte is human bone marrow mesenchymal stem cell. A pharmaceutical composition is used in the form of oral administration formulation or injection. The oral administration formulation is formulated in capsule, tablet, suspension, syrup or powder. A functional health food composition for preventing or treating diabetes, hyperlipidemia, hypercholesterolemia, circulatory system diseases contains 0.00001-10 weight% of chemerin. The health food is used in the form of caramel, chocolate, diet bar or snack. A cosmetic composition for treating obesity contains 0.00001-10 weight% of chemerin as an active ingredient. The cosmetic composition is used in the form of massage cream, body lotion, body cream, body oil, or body essence.
Abstract translation: 目的：提供一种抑制脂肪细胞分化和生长的组合物，用于治疗或预防循环系统疾病或缺血性心脏病。 构成：用于抑制脂肪细胞分化或生长的组合物含有0.00001〜15重量％的凯美宾。 脂肪细胞是人骨髓间充质干细胞。 药物组合物以口服给药制剂或注射剂的形式使用。 口服给药制剂配制成胶囊，片剂，悬浮液，糖浆或粉剂。 用于预防或治疗糖尿病，高脂血症，高胆固醇血症，循环系统疾病的功能保健食品组合物含有0.00001-10重量％的凯美瑞。 保健食品以焦糖，巧克力，饮食酒吧或小吃的形式使用。 用于治疗肥胖的化妆品组合物含有0.00001-10重量％的作为活性成分的凯美瑞。 化妆品组合物以按摩霜，身体乳液，身体霜，身体油或身体精华的形式使用。
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公开(公告)号：KR1020100005480A
公开(公告)日：2010-01-15
申请号：KR1020080065529
申请日：2008-07-07
Applicant: (주)아모레퍼시픽
IPC: A61K36/736 , A61P3/04
CPC classification number: A61K36/39 , A61K36/23 , Y10S514/909
Abstract: PURPOSE: A composition containing pharbitidis seed, Anthriscs aemula Schisch and their mixture for body sliming is provided to suppress adipocyte differentiation and reduce lipid level. CONSTITUTION: A composition for body sliming contains pharbitidis seed extract, Anthriscs aemula Schisch extract or their mixture as an active ingredient. A composition for suppressing adipocyte differentiation contains the pharbitidis seed extract, Anthriscs aemula Schisch extract or their mixture as an active ingredient. Mesenchymal stem cells from human bone marrow are differentiated to adipocytes. The composition for sliming is used in the form of cosmetic composition, health food or pharmaceutical composition.
Abstract translation: 目的：提供含有pharbitidis种子，Anthriscs aemula Schisch及其混合物用于身体瘦身的组合物，以抑制脂肪细胞分化和降低脂质水平。 构成：用于身体瘦身的组合物含有药草种子提取物，Anthriscs aemula Schisch提取物或其混合物作为活性成分。 用于抑制脂肪细胞分化的组合物含有苦楝子种子提取物，Anthriscs aemula Schisch提取物或其混合物作为活性成分。 来自人骨髓的间充质干细胞被分化成脂肪细胞。 用于苗条的组合物以化妆品组合物，保健食品或药物组合物的形式使用。
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公开(公告)号：KR1020090056584A
公开(公告)日：2009-06-03
申请号：KR1020070123798
申请日：2007-11-30
Applicant: (주)아모레퍼시픽 , 재단법인서울대학교산학협력재단
CPC classification number: A61K31/16
Abstract: A pharmaceutical composition regulating the activity of sphingosylphosphorylcholine(SPC) is provided to regulate cell proliferation, inflammation and pruritus and treat inflammmatin or pruritus of dermatitis such as atopic dermatitis. A pharmaceutical composition which regulates the activity of sphingosylphosphorylcholine(SPC) comprises a compound of the chemical formula 1 or its pharmaceutically allowable salt. In the chemical formula 1, X is O or S, Y is CH2 or carbonyl. R1 is hydrogen or C1-10 alkyl, R2 is hydrogen or methyl, but when X is O, either R1 or R2 cannot be hydrogen, R3 is C1-4 alkyl. A method for manufacturing a compound of the chemical formula 1a comprises: a step of reacting a compound of the chemical formula 2 and a compound of the chemical formula 3 under the presence of base to obtain a compound of the chemical formula 4; a step of stirring the compound of the chemical formula 4 under the presence of base to obtain a compound of the chemical formula 5; and a step of performing the peptide bond between the compound of the chemical formula 5 and a compound of the chemical formula 6 to obtain the compound of the chemical formula 1a.
Abstract translation: 提供调节肌动蛋白磷酰胆碱（SPC）活性的药物组合物，用于调节细胞增殖，炎症和瘙痒，并治疗诸如特应性皮炎等炎性炎症或皮炎瘙痒症。 调节鞘糖基磷酰胆碱（SPC）活性的药物组合物包含化学式1的化合物或其药学上可允许的盐。 在化学式1中，X为O或S，Y为CH 2或羰基。 R1是氢或C1-10烷基，R2是氢或甲基，但当X是O时，R1或R2不能是氢，R3是C1-4烷基。 制备化学式1a化合物的方法包括：使化学式2的化合物与化学式3化合物在碱存在下反应得到化学式4的化合物的步骤; 在碱的存在下搅拌化学式4的化合物以获得化学式5的化合物的步骤; 在化学式5的化合物与化学式6的化合物之间进行肽键的步骤，得到化学式1a的化合物。
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Patent Agency Ranking
公开(公告)号：KR1020170091567A
公开(公告)日：2017-08-09
申请号：KR1020170097086
申请日：2017-07-31
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/75 , A61K8/97 , A61Q19/005 , A61Q19/007
Abstract: 본발명은무라야패니쿨라타추출물을유효성분으로포함하는피부가려움증완화및 억제, 피부보습, 피부염증완화및 억제, 피부면역성강화, 피부과민반응개선또는아토피피부개선및 치료용조성물을개시한다.
Abstract translation: 本发明公开了一种村的同伴库拉其他皮肤瘙痒缓解包括提取物作为活性成分和抑制，皮肤保湿剂，皮肤炎症和抑制，皮肤免疫增强，皮肤致敏改善或特应性皮肤改善和治疗组合物。
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37.发明公开
公开(公告)号：KR1020170080548A
公开(公告)日：2017-07-10
申请号：KR1020170080225
申请日：2017-06-26
Applicant: (주)아모레퍼시픽
Abstract: 본발명은하이페리쿰추출물을유효성분으로함유하는지방유래줄기세포의줄기세포성증진용조성물및 피부세포증식용조성물을제공한다. 본발명의하이페리쿰추출물을유효성분으로함유하는조성물은지방유래줄기세포재생을촉진시키고표피의재생에관여하는피부표피기저층의전이-증폭세포의증식을촉진시켜, 피부볼륨감을증진시키고손상된피하지방의기능을회복시켜주므로, 피부볼륨감증대용피부미용및 성형용조성물및 피부볼륨감증대용피부외용제조성물에적용가능하다.
Abstract translation: 本发明提供用于增强含有超细胞提取物作为活性成分和皮肤细胞增殖用组合物的脂肪来源干细胞中的干细胞功能的组合物。 含有本发明的高轮渡谷氨酸提取物作为活性成分的组合物，以促进衍生的干细胞，并涉及在表皮皮肤表皮基底层发挥-通过促进扩增细胞的生长的转移的播放脂肪，增强皮肤体积损坏皮下感 可以将用于增加皮肤体积的用于皮肤美容和成型的组合物和用于增加皮肤体积的用于皮肤外用组合物施用。
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公开(公告)号：KR1020170080547A
公开(公告)日：2017-07-10
申请号：KR1020170080224
申请日：2017-06-26
Applicant: (주)아모레퍼시픽
Abstract: 본발명은하이페리쿰추출물을유효성분으로함유하는지방유래줄기세포의줄기세포성증진용조성물및 피부세포증식용조성물을제공한다. 본발명의하이페리쿰추출물을유효성분으로함유하는조성물은지방유래줄기세포재생을촉진시키고표피의재생에관여하는피부표피기저층의전이-증폭세포의증식을촉진시켜, 피부볼륨감을증진시키고손상된피하지방의기능을회복시켜주므로, 피부볼륨감증대용피부미용및 성형용조성물및 피부볼륨감증대용피부외용제조성물에적용가능하다.
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公开(公告)号：KR101743488B1
公开(公告)日：2017-06-07
申请号：KR1020100120371
申请日：2010-11-30
Applicant: (주)아모레퍼시픽
Abstract: 상기목적을달성하기위해, 비피더스균추출물을유효성분으로함유하는지방유래줄기세포의줄기세포성증진용조성물및 피부세포증식용조성물을제공한다. 본발명의조성물은비피더스균추출물을유효성분으로함유하여지방유래줄기세포의줄기세포성을증진시킴으로써미용또는성형목적의지방조직증가에유용하다. 그래서, 본발명의조성물은피부볼륨감을증진시키고, 지방유래줄기세포재생을촉진시키고손상된피하지방의기능을회복시켜주므로피부볼륨감증대용미용또는성형용조성물로활용가능하고, 피부볼륨감증대용피부외용제조성물로활용가능하다. 또한, 본발명의조성물은표피의재생에관여하는피부표피기저층의각질줄기세포와전이-증폭세포의증식을촉진할수 있으므로피부세포의재생을촉진할수 있다.
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公开(公告)号：KR101704481B1
公开(公告)日：2017-02-10
申请号：KR1020080065529
申请日：2008-07-07
Applicant: (주)아모레퍼시픽
IPC: A61K36/736 , A61P3/04
Abstract: 본발명은흑축추출물, 전호추출물또는이들의혼합물을유효성분으로함유하는슬리밍용조성물에관한것으로, 더욱상세하게는흑축추출물, 전호추출물또는이들의혼합물을포함함으로써지방세포분화를억제하고, 분화된지방세포내의지질체수준을감소시키는슬리밍용조성물에관한것이다.
Abstract translation: 目的：提供含有pharbitidis种子，Anthriscs aemula Schisch及其混合物用于身体瘦身的组合物，以抑制脂肪细胞分化和降低脂质水平。 构成：用于身体瘦身的组合物含有药草种子提取物，Anthriscs aemula Schisch提取物或其混合物作为活性成分。 用于抑制脂肪细胞分化的组合物含有苦楝子种子提取物，Anthriscs aemula Schisch提取物或其混合物作为活性成分。 来自人骨髓的间充质干细胞被分化成脂肪细胞。 用于苗条的组合物以化妆品组合物，保健食品或药物组合物的形式使用。
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