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公开(公告)号：KR1020110026321A
公开(公告)日：2011-03-15
申请号：KR1020090084167
申请日：2009-09-07
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A method and a kit for assessment of a neck skin age is provided to calculate the age of a neck skin by measuring a parameter including the skin color, winkle, elasticity of the neck skin. CONSTITUTION: In a method and a kit for assessment of a neck skin age, parameters including the skin color, winkle, elasticity of the neck skin are measured. The age of the neck skin is calculated from the measured parameter. The parameters are compared with the age of skin at ages. The grade level of individual parameter including the skin color, winkle, elasticity of the neck skin of a subject is measured. The grades of the measured individual parameters are compared with the age of the skin stored in a database.
Abstract translation: 目的：提供一种用于评估颈部皮肤年龄的方法和试剂盒，通过测量包括皮肤颜色，皱纹，颈部皮肤弹性的参数来计算颈部皮肤的年龄。 构成：在用于评估颈部皮肤年龄的方法和试剂盒中，测量包括皮肤颜色，皱纹，颈部皮肤的弹性的参数。 颈部皮肤的年龄由测量参数计算。 参数与年龄的皮肤年龄进行比较。 测量个体参数的级别，包括皮肤颜色，皱纹，受试者颈部皮肤的弹性。 将测量的各个参数的等级与存储在数据库中的皮肤的年龄进行比较。
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32.发明公开지황, 감초, 의이인, 맥아, 모과, 오가피, 또는 갈근 추출물을 함유하는 지방 세포 분화 촉진 조성물 无效含有REHMANNIA GLUTINOSA，RADIX GLYCYRRHIZAE，SEMEN COICIS，FRUCTUS HORDEI，FRUCTUS CHAENOMELIS，CORTEX ACANTHOPANACIS或RADIX PUERARIAE萃取物的组合物用于促进ADIPOCYTE差异
公开(公告)号：KR1020110001407A
公开(公告)日：2011-01-06
申请号：KR1020090058929
申请日：2009-06-30
Applicant: (주)아모레퍼시픽
IPC: A61K8/97 , A61Q19/08 , A61K36/804 , A61K36/484
CPC classification number: A61K8/97 , A61K36/254 , A61K36/484 , A61K36/488 , A61K36/732 , A61K36/804 , A61K36/899 , A61K36/8994 , A61K2800/91 , A61Q19/08 , A61K2300/00
Abstract: PURPOSE: A composition containing medicinal herb extract is provided to promote adipocyte differentiation and to enhance anti-wrinkling, elasticity enhancement and anti-aging. CONSTITUTION: A composition for skin elasticity, anti-wrinkling, and anti-aging contains extract of Rehmannia glutinosa, Radix glycyrrhizae, Semen coicis, Fructus hordei, Fructus chaenomelis, Cortex acanthopanacis, and Radix puerariae as an active ingredient. An external use composition contains the extract as an active ingredient.
Abstract translation: 目的：提供含有药草提取物的组合物，以促进脂肪细胞分化，增强抗皱，弹性增强和抗衰老。 构成：用于皮肤弹性，抗皱和抗衰老的组合物含有地黄，甘草，精is，枸杞，枸杞，茯苓和葛根的提取物作为活性成分。 外用组合物含有提取物作为活性成分。
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公开(公告)号：KR1020100098258A
公开(公告)日：2010-09-06
申请号：KR1020090033750
申请日：2009-04-17
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: An external use skin composition containing pine root extract is provided to remove free radical, to protect cellular membrane damage, and to suppress reactive oxygen species(ROS). CONSTITUTION: An external use skin composition contains pine root extract. The composition is used for anti-aging, and cell protection by promoting HSP70 generation. The external use skin composition contains 0.001-99 weight% of pine root extract based on total weight. The composition further contains cosmetically and dermatologically acceptable medium and/or substrate. The composition is used in the form of solution, gel, solid, emulsion, suspension, microemulsion, microcapsule, cream, skin, lotion, or spray. The composition is used for anti-aging and skin regeneration.
Abstract translation: 目的：提供含有松果提取物的外用皮肤组合物，以去除自由基，保护细胞膜损伤和抑制活性氧（ROS）。 构成：外用皮肤组合物含有松果提取物。 该组合物用于促进HSP70产生的抗衰老和细胞保护。 外用皮肤组合物含有0.001-99重量％的松根提取物，基于总重量。 组合物还含有美容和皮肤病学可接受的培养基和/或底物。 该组合物以溶液，凝胶，固体，乳液，悬浮液，微乳液，微胶囊，霜剂，皮肤，洗剂或喷雾剂的形式使用。 该组合物用于抗衰老和皮肤再生。
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公开(公告)号：KR1020100059305A
公开(公告)日：2010-06-04
申请号：KR1020080118035
申请日：2008-11-26
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A skin composition for external use containing Broussonetiae Fructus extract is provided to ensure skin barrier strengthening and skin moisturization and to be used in cosmetic products and in the medicinal field. CONSTITUTION: A composition for external use contains Broussonetiae Fructus extract as an active ingredient. The Broussonetiae Fructus extract enhances PPARs(peroxisome proliferator-activated receptors), fillatrin, trasglutaminase 1(TGase 1), or an hyaluronic acid synthase 1(HAS2) gene expression. The composition is used in the form of a lotion, eye cream, nutrition cream, massage cream, cleansing cream, cleansing foam, cleansing water, powder, essence, pack, or ointment.
Abstract translation: 目的：提供含有Broussonetiae Fructus提取物的外用皮肤组合物，以确保皮肤屏障增强和皮肤保湿，并用于化妆品和药用领域。 构成：外用组合物含有布鲁氏酵母提取物作为活性成分。 Broussonetiae Fructus提取物增强PPARs（过氧化物酶体增殖物激活受体），fillatrin，trasglutaminase 1（TGase 1）或透明质酸合酶1（HAS2）基因表达。 该组合物以洗剂，眼霜，营养霜，按摩霜，清洁霜，清洁泡沫，清洁水，粉末，精华，包装或软膏的形式使用。
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35.发明公开백화사설초, 대황, 닥나무 추출물을 함유하는 미백용 피부외용제 조성물 有权含有OLDENLANDIA DIFFUSA WILLD，RHEUM UNDULATUM和BROUSSONETIA KAZINOKI EXTRACT的外用皮肤应用的白色组合物
公开(公告)号：KR1020100059033A
公开(公告)日：2010-06-04
申请号：KR1020080117660
申请日：2008-11-25
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q19/02 , A61K8/97 , A61K2800/782
Abstract: PURPOSE: An external use skin composition for skin whitening containing natural products extract is provided to ensure skin whitening effect and melanogenesis suppression with stability to the skin. CONSTITUTION: An external use skin composition contains extract of Oldenlandia Diffusa Willd, Rheum undulatum LINNE, and Broussonetia kazinoki Sieb as an active ingredient. The extract of Oldenlandia Diffusa Willd, Rheum undulatum LINNE, and Broussonetia kazinoki Sieb is mixed in a weight ratio of 1-4:1-4:1-4.
Abstract translation: 目的：提供含有天然产物提取物的皮肤美白外用皮肤组合物，以确保皮肤美白效果和对皮肤稳定的黑素生成抑制作用。 构成：外用皮肤组合物含有Oldenlandia Diffusa Willd，Rheum undulatum LINNE和Broussonetia kazinoki Sieb的提取物作为活性成分。 将Oldenlandia Diffusa Willd，Rheum undulatum LINNE和Broussonetia kazinoki Sieb的提取物以1-4：1-4：1-4的重量比混合。
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Patent Agency Ranking36.发明公开
公开(公告)号：KR1020100055734A
公开(公告)日：2010-05-27
申请号：KR1020080114595
申请日：2008-11-18
Applicant: (주)아모레퍼시픽
IPC: A61K31/366 , A61K31/352 , A61P17/00
Abstract: 본발명은 7,3',4'-트리하이드록시이소플라본을유효성분으로함유하는피부장벽강화용또는보습용피부외용제조성물에관한것으로, 보다상세하게는오르토-디하이드록시이소플라본인 7,3',4'-트리하이드록시이소플라본을함유함으로써생체내 퍼옥시좀증식체활성화수용체알파(PPAR α)를활성화시켜그 발현을증가시킬뿐만아니라, 필라그린유전자, 트랜스글루타미네이즈 1 유전자및 히알루론산합성효소 2 유전자의발현을증가시켜피부각질세포의분화를유도하고피부장벽을강화하며피부수분함량을증가시키는피부외용제조성물에관한것이다.
Abstract translation: 目的：提供含有7,3'，4'-三羟基异黄酮的外用皮肤组合物，以诱导角质形成细胞的分化并增强皮肤的保湿作用。 构成：用于保湿和增强皮肤屏障的外用皮肤组合物含有0.001-10重量％的作为活性成分的7,3'，4'-三羟基异黄酮。 7,3'，4'-三羟基异黄酮激活过氧化物酶体增殖物激活受体（PPARs）。 7,3'，4'-三羟基异黄酮增加了丝胶蛋白，转谷氨酰胺酶1和透明质酸合成酶2基因的表达。 该组合物以收敛剂，眼霜，按摩膏，清洁霜，清洁泡沫，清洁水，粉末，精华，包装或软膏的形式使用。
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公开(公告)号：KR1020100036549A
公开(公告)日：2010-04-08
申请号：KR1020080095816
申请日：2008-09-30
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A mask pack composition for attachment is provided to improve skin elasticity and smooth skin wrinkle and enhance skin density of epidermal layer and dermal layer. CONSTITUTION: A mask pack composition for attachment contains red ginseng saponin, Camellia, Tussilago farfara L. extract, Mutabilis flower or Pomegranate extract. The composition contains 0.001-10 weight% of enzyme-treated red ginseng saponin. A mask pack for attachment is used in the form of wet type, cross-linking aqueous gel or non-cross linking aqueous gel.
Abstract translation: 目的：提供用于附着的面膜包组合物，以改善皮肤弹性和光滑的皮肤皱纹，增强表皮层和真皮层的皮肤密度。 构成：用于附着的面膜包组合物含有红参皂甙，山茶花，龙舌兰提取物，Mutabilis花或石榴提取物。 该组合物含有0.001-10重量％的酶处理的红参皂苷。 用于附着的面膜包以湿式，交联水凝胶或非交联水凝胶的形式使用。
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公开(公告)号：KR100864677B1
公开(公告)日：2008-10-23
申请号：KR1020070029255
申请日：2007-03-26
Applicant: (주)아모레퍼시픽
IPC: C07C233/07 , C07C233/10
Abstract: 본 발명은 항비만 효과를 나타내는 하기 화학식 1로 표시되는 3,5-디히드록시벤조산 유도체 화합물 및 이의 제조방법에 관한 것이다:
[화학식 1]
상기 식 중, R은 아다만틸, 시클로헥실 또는 헥실이다.
3,5-디히드록시벤조산 유도체, 항비만, 루시퍼라아제, IDH3α, CPT1, 혈당-
公开(公告)号：KR100851044B1
公开(公告)日：2008-08-12
申请号：KR1020070083905
申请日：2007-08-21
Applicant: (주)아모레퍼시픽
Abstract: 3,5-Dihydroxy benzamide derivatives are provided to whiten the skin due to a depigmenting activity and improve stability in aqueous solution and organic solvent in formulation by inhibiting structure change. A cosmetic composition for whitening the skin comprises 0.01-20 wt.% of 3,5-dihydroxy benzamide derivatives represented by a formula(1), wherein a hydroxyl group is located in the 2,3-, 2,4-, 2,5-, 3,4- or 3,5-site, and is used in forms of emulsion, cream, cosmetic lotion, essence, pack, gel, powder, makeup base, foundation, lotion, ointment, patch, beauty solution, cleansing foam, cleansing cream, cleansing water, body lotion, body cream, body oil, body essence, shampoo, rinse, body cleanser, soap, hair dye or spray.
Abstract translation: 提供3,5-二羟基苯甲酰胺衍生物，由于脱色活性而使皮肤变白，并通过抑制结构变化提高配方中水溶液和有机溶剂的稳定性。 用于使皮肤美白的化妆品组合物包含0.01-20重量％的由式（1）表示的3,5-二羟基苯甲酰胺衍生物，其中羟基位于2,3-，2,4-， 5-，3,4-或3,5-位，并以乳液，霜剂，化妆水，精华，包装，凝胶，粉末，化妆底，粉底，洗剂，软膏，贴片，美容液，清洁剂的形式使用 泡沫，清洁霜，清洁水，身体乳液，身体霜，身体油，身体精华，洗发水，漂洗，身体清洁剂，肥皂，染发剂或喷雾剂。
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公开(公告)号：KR100845511B1
公开(公告)日：2008-07-10
申请号：KR1020070029253
申请日：2007-03-26
Applicant: (주)아모레퍼시픽
IPC: C07D317/68 , A61K31/357
Abstract: A hydroxamic acid derivative is provided to induce the activity increase of each promoter of IDH3alpha and CPT1 involving with energy consumption metabolism, thereby being usefully used for preventing or treating diseases related to dyslipidemia such as obesity, hyperlipidemia and diabetes. A hydroxamic acid is represented by a formula(1), wherein R1 is CONH, NHCO, CONR4 or NR4CO(where R4 is H or C1-10 alkyl); R2 is -(CH2)n-(where n is 0 or 1); and R3 is H or C1-10 alkyl. A method for preparing the hydroxamic acid comprises the steps of: (a) reacting an anhydrous compound synthesized by reacting ethyl chloroformate with piperonic acid using pyridine or N-methyl morpholine as a solvent with methyl 4-amino benzoate or 4-amino phenyl acetic acid ethyl ester at a temperature of 10-20 deg.C using pyridine or N-methyl morpholine as a solvent to prepare a benzamide compound; (b) reacting the benzamide with an alkyl halide selected from the group consisting of bromomethane, bromoethane, bromopropane, bromo isopropane, bromo butane, and bromo tert-butane to substitute an amide bond of the benzamide with an alkyl group; (c) hydrolyzing methyl ester in the benzamide obtained from the step(a) or the benzamide compound obtained from the step(b) to prepare an acid and reacting the acid with ethyl chloroformate using pyridine or N-methyl morpholine as a solvent to covert the acid into an anhydrous compound; and (d) reacting the anhydrous compound with hydroxyl amine chloride or N-methyl hydroxyl amine chloride at a temperature of 0-10 deg.C using pyridine or N-methyl morpholine as a solvent to obtain the product of the formula(1). An agent for anti-obese, treating diabetes or hyperlipidemia comprises the hydroxamic acid.
Abstract translation: 提供异羟肟酸衍生物以诱导与能量代谢相关的IDH3α和CPT1的每种启动子的活性增加，从而有效地用于预防或治疗与脂肪血症如肥胖症，高脂血症和糖尿病有关的疾病。 异羟肟酸由式（1）表示，其中R1是CONH，NHCO，CONR4或NR4CO（其中R4是H或C1-10烷基）; R2是 - （CH2）n-（其中n是0或1）; 并且R 3是H或C 1-10烷基。 制备异羟肟酸的方法包括以下步骤：（a）使吡啶或N-甲基吗啉作为溶剂与4-氨基苯甲酸甲酯或4-氨基苯基乙酸反应，使氯甲酸乙酯与胡椒酸反应合成的无水化合物 乙酯，使用吡啶或N-甲基吗啉作为溶剂，在10-20℃的温度下制备苯甲酰胺化合物; （b）使苯甲酰胺与选自溴甲烷，溴乙烷，溴丙烷，溴异丙烷，溴丁烷和溴叔丁烷的烷基卤反应，以苯甲酰胺与烷基取代; （c）水解由步骤（a）获得的苯甲酰胺中的甲酯或由步骤（b）获得的苯甲酰胺化合物制备酸，并使用吡啶或N-甲基吗啉作为溶剂使酸与氯甲酸乙酯反应，从而使 将酸变成无水化合物; 和（d）使用吡啶或N-甲基吗啉作为溶剂，在0-10℃的温度下使无水化合物与羟胺或N-甲基羟胺氯化物反应，得到式（1）的产物。 用于抗肥胖，治疗糖尿病或高脂血症的药物包括异羟肟酸。
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