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31.发明公开형질 전환 세포주와 백반증 마우스를 이용한 백모 방지 물질 스크리닝 방법 및 그 백모 방지 물질을 함유하는 백모방지용 조성물 有权使用稳定的细胞系和加速的VITILIGO小鼠筛选抗灰霉素成分的方法，以及含有抗灰白色成分的组合物。
公开(公告)号：KR1020130002307A
公开(公告)日：2013-01-07
申请号：KR1020120151005
申请日：2012-12-21
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A method for screening a material which prevents gray hair using a transgenic cell line and a vitiligo model mouse(C57bl/6-Mitfmi-vit) and a composition containing the same are provided to simultaneously recognize MITF, tyrosinase, and TRP2 changes in gene, protein, and melanin levels. CONSTITUTION: A melan-a melanocyte cell line tyrosinase-GLuc(KCLRF-BP-00163) is prepared by transforming with an expression vector, pTyrosinase-GLuc. A method for screening a material which prevents gray hair comprises: a step of treating a candidate material which prevents gray hair to the transgenic melanocyte cell line; a step of measuring the production quantity of GLuc existing in a medium; a step of applying the candidate material onto the back of a vitiligo mouse; and a step of measuring the melanin quantity of newly grown hair from the back of vitiligo mouse.
Abstract translation: 目的：提供使用转基因细胞系和白癜风模型小鼠（C57b1 / 6-Mitfmi-vit）及其组合物筛选防止灰白毛的材料的方法，以同时识别MITF，酪氨酸酶和TRP2的变化 基因，蛋白质和黑色素水平。 构成：通过用表达载体pTyrosinase-GLuc转化制备黑色素黑素细胞细胞系酪氨酸酶GLuc（KCLRF-BP-00163）。 用于筛选防止灰白毛发的材料的方法包括：将防止灰白色的候选材料处理到转基因黑素细胞细胞系的步骤; 测量介质中存在的GLuc的生产量的步骤; 将候选材料应用于白癜风小鼠背部的步骤; 以及从白癜风小鼠的背部测定新生毛发的黑色素量的步骤。
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32.发明公开세콰이어 캘러스 추출물을 함유하는 지방유래 줄기세포의 줄기세포성 증진용 및 피부세포 증식용 조성물 有权用于促进ADIPOSE衍生的干细胞的STEMNESS的化妆品组合物和含有SEQUYIA CALLUS细胞提取物的增殖皮肤细胞
公开(公告)号：KR1020120058829A
公开(公告)日：2012-06-08
申请号：KR1020100120313
申请日：2010-11-30
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/14 , A61K8/00 , A61K8/0216 , A61K8/0225 , A61K8/06 , A61K8/97 , A61K8/981 , A61K35/00 , A61K35/12 , A61K35/28 , A61K35/545 , A61K36/00 , A61K36/13 , A61M35/00 , A61Q19/00
Abstract: PURPOSE: A composition containing Sequoia callus extract is provided to promote regeneration of adipose-derived stem cells and to recover damaged subcutaneous fat. CONSTITUTION: A composition for enhancing the stemness of adipose-derived stem cells(hADSCs) contains Sequoia callus extract as an active ingredient. The composition enhances CD29 and CD44 expression level. A composition for enhancing skin cell proliferation contains the extract as an active ingredient. The skin cell is transit-amplifying cells(TA cells). The composition contains 0.0001-10 wt% of the extract. A skin care method comprises a step of treating the composition on the skin.
Abstract translation: 目的：提供含有红杉愈伤组织提取物的组合物，以促进脂肪来源的干细胞的再生并恢复损伤的皮下脂肪。 构成：用于增强脂肪干细胞（hADSC）的干性的组合物含有红杉愈伤组织提取物作为活性成分。 该组合物增强CD29和CD44表达水平。 用于增强皮肤细胞增殖的组合物含有提取物作为活性成分。 皮肤细胞是转运扩增细胞（TA细胞）。 组合物含有0.0001-10重量％的提取物。 护肤方法包括在皮肤上处理组合物的步骤。
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公开(公告)号：KR101134703B1
公开(公告)日：2012-04-13
申请号：KR1020090085335
申请日：2009-09-10
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 훈자 살구 추출물을 함유하는 화장료 조성물에 관한 것으로, 보다 상세하게는 훈자 지방의 살구 추출물을 유효성분으로 함유하여 피부에 수분을 더욱 원활히 공급하고 들떠있는 각질을 감소시키며 피부결을 부드럽게 할 뿐만 아니라, 훈자 살구 추출물의 강력한 항산화 효능이 피부에 존재하는 활성산소를 제거하고 피부 표면 케라틴 변성과 세포 손상을 억제하여 피부 수분 손실이나 피부가 칙칙해지는 현상을 개선하여 궁극적으로 피부 수분량의 증가와 피부결 개선 효과를 나타내는 화장료 조성물에 관한 것이다.
훈자 살구 추출물, 보습, 각질 제거, 항산화, 피부결 개선, 피부 안색 밝아짐, 화장료 조성물-
公开(公告)号：KR101082272B1
公开(公告)日：2011-11-09
申请号：KR1020090015228
申请日：2009-02-24
Applicant: (주)아모레퍼시픽
Abstract: 본발명은식물의새싹추출물을함유한조성물에관한것으로, 세쿼이어새싹, 빌베리새싹, 복숭아새싹, 발아배추, 발아브로콜리, 발아해바라기및 발아케일로부터추출한새싹추출물을유효성분으로포함하고있다. 상기조성물은피부세포의증식을촉진하고, 피부줄기세포의생존과증식을증진시킴으로써, 피부노화를지연및 개선하는효능이뛰어나다.
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公开(公告)号：KR1020100080991A
公开(公告)日：2010-07-14
申请号：KR1020090000236
申请日：2009-01-05
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A hair cosmetic composition containing black soybean extract and blueberry extract is provided to have nutrition to hair follicle and to strengthen hair follicle. CONSTITUTION: A hair cosmetic composition contains black soybean extract and blueberry extract as an active ingredient. The composition further contains black pearl extract or royal jelly extract as an active ingredient. The volume ratio of the black soybean extract and blueberry extract is 5:5-9:1. The composition is used in the form of hair tonic, hair essence, hair serum, scalp treatment, hair treatment, hair conditioner, hair shampoo, or hair lotion.
Abstract translation: 目的：提供含有黑豆提取物和蓝莓提取物的头发化妆品组合物以对毛囊具有营养并加强毛囊。 构成：毛发化妆品含有黑豆提取物和蓝莓提取物作为活性成分。 该组合物还含有黑珍珠提取物或蜂王浆提取物作为活性成分。 黑豆提取物和蓝莓提取物的体积比为5：5-9：1。 该组合物以头发补品，头发精华，头发血清，头皮治疗，头发处理，护发素，洗发剂或洗发剂的形式使用。
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Patent Agency Ranking
公开(公告)号：KR1020100010433A
公开(公告)日：2010-02-01
申请号：KR1020080096663
申请日：2008-10-01
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K36/48 , A61K2236/331 , A61Q5/02 , A61Q5/12 , Y10S514/881
Abstract: PURPOSE: A hair cosmetic composition containing black soybean-brewed water is provided to enhance anti-oxidation, hair glossiness, and scalp effect. CONSTITUTION: A hair cosmetic composition contains 0.01-10.0 weight% of black soybean-brewed water. The water is isolated through low temperature elution. The black soybean is steamed and dried. The composition further contains 0.01~10.0 weight% of black sesame extract and cacao seed extract. The composition contains dihydroxy acetic acid as an antiseptic. The composition is used in the form of hair tonic, hair nutrition lotion, hair essence, hair serum scalp treatment, hair treatment, hair conditioner, hair shampoo or hair lotion.
Abstract translation: 目的：提供含有黑大豆酿造水的头发化妆品，以增强抗氧化，头发光泽和头皮效果。 构成：头发化妆品组合物含有0.01-10.0重量％的黑豆酿造水。 水通过低温洗脱分离。 将黑豆蒸并干燥。 该组合物还含有0.01〜10.0重量％的黑芝麻提取物和可可籽提取物。 该组合物含有二羟基乙酸作为防腐剂。 该组合物以头发补品，头发营养洗剂，头发精华，头发血清头皮治疗，头发处理，护发素，洗发剂或洗发剂的形式使用。
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37.发明授权ＧＤＮＦ를 포함하는 모발의 멜라닌 생성 촉진용 조성물,ＧＤＮＦ를 이용하는 모발의 멜라닌 생성 촉진 방법 및ＧＤＮＦ의 발현정도를 이용하여 모발 멜라닌 생성촉진제를 스크리닝하는 방법 有权用于增强包含GDNF的发胶中的造血作用的组合物，使用GDNF增强毛发发生变色的方法，以及使用GDNF表达水平筛选毛发发生增强的方法
公开(公告)号：KR100889460B1
公开(公告)日：2009-03-17
申请号：KR1020070118013
申请日：2007-11-19
Applicant: (주)아모레퍼시픽 , 재단법인서울대학교산학협력재단
CPC classification number: A61K8/64 , A61K38/185 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/08 , Y10S514/881
Abstract: A white hair suppressing composition and a kit for melanogenesis promotion of hair are provided to promote melanogenesis of hair using GDNF protein or gene ciphering protein. A white hair suppressing composition comprises a neurotrophic factor receptor genesis growth factor as an active ingredient. The white hair suppressing composition promotes melanogenesis of hair by promoting expression of microphthalmia-associated transcription factor. The white hair suppressing composition is coated scalp or hair. A kit for melanogenesis promotion of hair comprises gene ciphering the neurotrophic factor receptor genesis growth factor or protein.
Abstract translation: 提供白发抑制组合物和用于促进头发黑素生成的试剂盒，以促进使用GDNF蛋白质或基因加密蛋白质的头发黑素生成。 白发抑制组合物包含神经营养因子受体起因生长因子作为活性成分。 白发抑制组合物通过促进微小珠蛋白相关转录因子的表达来促进头发的黑素生成。 白头发抑制组合物是头皮或头发。 用于黑发生长促进毛发的试剂盒包括加密神经营养因子受体起源生长因子或蛋白质的基因。
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公开(公告)号：KR102200014B1
公开(公告)日：2021-01-08
申请号：KR1020140053471
申请日：2014-05-02
Applicant: (주)아모레퍼시픽
Abstract: 본발명은쿠메스트롤을포함하는콩 추출물을유효성분으로포함하는갱년기질환의예방등에대한조성물에관한것으로, 보다상세하게는쿠메스트롤을포함하는발아발효콩추출물을포함하는갱년기질환의예방등에대한조성물에관한것이다.
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公开(公告)号：KR101899094B1
公开(公告)日：2018-09-14
申请号：KR1020170018128
申请日：2017-02-09
Applicant: (주)아모레퍼시픽
Abstract: 본발명에따른실시예에의한모낭및 상기모낭에결합되는털을포함하는털 조직을배양하는마이크로플루이딕디바이스로서, 몸체, 상기몸체내의일측에형성되며, 내부에배지(培地) 및콜라겐젤이적어도일부채워질수 있는적어도하나의조직배양공간및 상기조직배양공간과연결되며, 상기몸체의일측을관통하는조직배양공간입구를포함하며, 상기모낭은상기조직배양공간내에위치하고, 상기털은상기조직배양공간입구를관통할수 있다.
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公开(公告)号：KR101874790B1
公开(公告)日：2018-07-05
申请号：KR1020110122623
申请日：2011-11-23
Applicant: (주)아모레퍼시픽
CPC classification number: C12N5/0698 , A61F2/10 , A61L27/24 , A61L27/3804 , A61L27/3813 , A61L27/3886 , A61L27/60
Abstract: 본발명은섬유아세포, 각질형성세포및 멜라닌형성세포를함유하는인공피부에관한것으로, 멜라닌형성세포를함유함으로써피부연구에대하여자극, 미백및 노화와같은다양한영역의연구를동시에행할수 있는인공피부모델을제공할수 있다. 또한본 발명의인공피부는진피층을 2 이상의층을포함하는것을특징으로하는인공피부를제공하여진피수축현상으로인한조직학적변형이적어생리적부작용이없으며, 인체상관성이높은인공피부모델을제공할수 있다.
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