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公开(公告)号：KR1020140132318A
公开(公告)日：2014-11-17
申请号：KR1020140139596
申请日：2014-10-16
Applicant: (주)아모레퍼시픽
IPC: A61K8/97 , A61K36/8888 , A61Q19/00 , A61P17/00
Abstract: 본 발명은 인간 중간엽 줄기세포의 지방세포로의 분화를 촉진하는 조성물에 관한 것으로, 보다 상세하게는 건율, 권백, 노회, 단삼, 박하, 반하, 소맥, 어성초, 원지 및 조각인 추출물 중 1종 이상을 유효성분으로 함유하여 인간 중간엽줄기세포를 지방세포로 분화하는 것을 촉진시킴으로써 지방체(Lipid droplet)를 생성하여, 특정 부위의 피부의 볼륨감을 증대시키는 미용 또는 성형용 조성물에 관한 것이다.
Abstract translation: 本发明涉及促进人间充质干细胞分化为脂肪细胞的组合物，更具体地说，涉及一种化妆品或整形外科用组合物，其包含栗酸，卷柏，芦荟，丹参，薄荷中的一种或多种 ，半夏，小麦，Huttuynia cordata，墨西哥乳脂和皂角提取物作为活性成分，促进人间充质干细胞向脂肪细胞的分化，并产生脂滴，从而增加皮肤特定区域的体积。
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公开(公告)号：KR1020140132317A
公开(公告)日：2014-11-17
申请号：KR1020140139595
申请日：2014-10-16
Applicant: (주)아모레퍼시픽
IPC: A61K8/97 , A61K36/534 , A61Q19/00 , A61P17/00
Abstract: 본 발명은 인간 중간엽 줄기세포의 지방세포로의 분화를 촉진하는 조성물에 관한 것으로, 보다 상세하게는 건율, 권백, 노회, 단삼, 박하, 반하, 소맥, 어성초, 원지 및 조각인 추출물 중 1종 이상을 유효성분으로 함유하여 인간 중간엽줄기세포를 지방세포로 분화하는 것을 촉진시킴으로써 지방체(Lipid droplet)를 생성하여, 특정 부위의 피부의 볼륨감을 증대시키는 미용 또는 성형용 조성물에 관한 것이다.
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公开(公告)号：KR101349245B1
公开(公告)日：2014-01-16
申请号：KR1020100117492
申请日：2010-11-24
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 피부 미용 또는 성형용 조성물에 관한 것으로서, 보다 상세하게는 관중(
Crassirhizomae
Rhizoma ), 오약(
Linderae
Radix ), 계피(
Cinnamomum
cassia ) 및 고삼(
Saphora
flavescens ) 추출물로 이루어진 군에서 선택된 1종 이상을 유효성분으로 함유하여 사람의 중간엽줄기세포를 지방세포로 분화시키는 것을 촉진하는 피부 미용 또는 성형용 조성물에 관한 것이다.-
公开(公告)号：KR1020120002965A
公开(公告)日：2012-01-09
申请号：KR1020110137405
申请日：2011-12-19
Applicant: (주)아모레퍼시픽
IPC: A61K36/48 , A61K36/9062 , A61K36/58 , A61P17/00
CPC classification number: A61K36/48 , A61K8/97 , A61K36/58 , A61K36/9062 , A61Q19/08
Abstract: PURPOSE: A composition which promotes differentiation of human mesenchymal stem cells into adipocytes is provided to enhance skin volume and elasticity and to prevent wrinkles. CONSTITUTION: An external use skin composition for anti-aging contains extract of Spatholobus suberectus Dunn., Alpinia officinarum Hance, or Angelica pubescens for. biserrata Shan Etyuan as an active ingredient. The composition is used for anti-wrinkling or elasticity improvement. The mesenchymal stem cells are derived from human. A pharmaceutical composition for promoting differentiation of adipocytes contains extract of Mucunae Caulis, Alpiniae officinari Rhizoma or Araliae cordatae Radix as an active ingredient.
Abstract translation: 目的：提供促进人间充质干细胞分化为脂肪细胞的组合物，以增强皮肤体积和弹性，并防止皱纹。 构成：外用皮肤抗衰老组合物含有Spatholobus suberectus Dunn，Alpinia officinarum Hance或Angelica pubescens的提取物。 biserrata Shan Eyuanuan作为活性成分。 该组合物用于抗皱或弹性改善。 间充质干细胞来源于人。 用于促进脂肪细胞分化的药物组合物含有木瓜（Mucunae Caulis），天竺葵（Alpiniae officinari Rhizoma）或堇菜（Araliae cordatae Radix）的提取物作为活性成分。
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公开(公告)号：KR1020110000717A
公开(公告)日：2011-01-05
申请号：KR1020100117493
申请日：2010-11-24
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition for skin care or plasty is provided to promoter differentiation of human mesenchymal stem cells to adipocytes. CONSTITUTION: A composition for promoting differentiation of adipocytes contains Saphora flavescens extract as an active ingredient. The composition also contains Crassirhizomae Rhixoma, Linderae Radix, or Cinnamomum cassia extract as an active ingredient. The extract is obtained using water, or organic solvent such as ethanol. The composition is used in the form of external use composition such as massage cream, pack and gel or a cosmetic composition such as lotion, ointment, gel, cream, patch or spray.
Abstract translation: 目的：提供用于皮肤护理或整形的组合物以促进人间充质干细胞向脂肪细胞的分化。 构成：用于促进脂肪细胞分化的组合物含有黑曲霉提取物作为活性成分。 该组合物还含有Crassirhizomae Rhixoma，Linderae Radix或Cinnamomum cassia提取物作为活性成分。 提取物是使用水或有机溶剂如乙醇获得的。 组合物以外用组合物的形式使用，例如按摩膏，包装和凝胶或化妆品组合物如洗剂，软膏，凝胶，霜剂，贴片或喷雾剂。
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Patent Agency Ranking
公开(公告)号：KR1020100105093A
公开(公告)日：2010-09-29
申请号：KR1020090023936
申请日：2009-03-20
Applicant: (주)아모레퍼시픽
IPC: A61K8/97 , A61K36/9062 , A61K36/58 , A61P17/00
Abstract: PURPOSE: A composition for promoting differentiation of human mesenchymal stem cells to adipocytes is provided to enhance volume and elasticity and to ensure anti-wrinkle effect. CONSTITUTION: An external composition for promoting adipocyte differentiation contains extract of Spatholobus suberectus Dunn., Alpinia officinarum Hance, Angelica pubescens for. biserrata Shan Etyuan, or Melia azedarach var. japonica Makino as an active ingredient. The composition promotes differentiation of mesenchymal stem cells to adipocytes. The mesenchymal stem cell is human mesenchymal stem cell. The composition contains the extract in 0.0001-30 weight% based on total weight. The composition enhances skin volume and elasticity.
Abstract translation: 目的：提供用于促进人间充质干细胞向脂肪细胞分化的组合物，以增强体积和弹性，并确保抗皱效果。 构成：用于促进脂肪细胞分化的外用组合物含有Spatholobus suberectus Dunn，Alpinia officinarum Hance，Angelica pubescens的提取物。 biserrata Shan娥或Melia azedarach var。 粳稻作为活性成分。 该组合物促进间充质干细胞向脂肪细胞的分化。 间充质干细胞是人间充质干细胞。 该组合物含有基于总重量的0.0001-30重量％的提取物。 该组合物增强皮肤体积和弹性。
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公开(公告)号：KR1020100012076A
公开(公告)日：2010-02-05
申请号：KR1020080073605
申请日：2008-07-28
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing medicinal herb extract for skin care or plastic surgery is provided to promote differentiation of human mesenchymal stem cells to adipocytes and improve adipose. CONSTITUTION: A composition for promoting differentiation of adipocytes contains Crassirhizomae Rhizoma, Linderae Radix, Cinnamomum cassia, and Saphora flavescens extract as an active ingredient. The medicinal herb extract is obtained using organic solvent such as water and ethanol. The composition enhances adipose. The composition promotes differentiation of human mesenchymal stem cells to adipocytes. The composition is used in the form of skin softener, nutrition lotion, massage cream, pack, gel, or skin viscosity type cosmetic product.
Abstract translation: 目的：提供含有用于护肤或整形手术的药用草药提取物的组合物，以促进人类间充质干细胞向脂肪细胞分化并改善脂肪。 构成：用于促进脂肪细胞分化的组合物含有Crassirhizomae Rhizoma，Linderae Radix，Cinnamomum Cassia和Saphora flavescens提取物作为活性成分。 使用有机溶剂如水和乙醇获得草药提取物。 组合物增强脂肪。 该组合物促进人间充质干细胞向脂肪细胞的分化。 该组合物以皮肤柔软剂，营养乳液，按摩霜，包装，凝胶或皮肤粘度型化妆品的形式使用。
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38.发明公开괄루인 또는 마자인 추출물을 함유하는 인간중간엽줄기세포의 지방세포로의 분화 촉진용 조성물 无效用于促进人类细胞干细胞分化为含有TRICHOSANTHIS SEMEN或CANNABIS SEMEN的提取物的细胞的组合物
公开(公告)号：KR1020100008541A
公开(公告)日：2010-01-26
申请号：KR1020080069083
申请日：2008-07-16
Applicant: (주)아모레퍼시픽
IPC: A61K36/428 , A61K36/60 , A61P3/10
Abstract: PURPOSE: A composition promoting adipocyte differentiation of human mesenchymal stem cells is provided to ensure volume and elasticity of the skin and effectively prevent or treat diabetes type 2. CONSTITUTION: A composition for promoting adipocyte differentiation contains Trichosanthis Semen extract or Cannabis Semen extract as an active ingredient. A composition for preventing or treating diabetes contains the Trichosanthis Semen extract or Cannabis Semen extract as an active ingredient. The composition promotes differentiation of human mesenchymal stem cells to adipocytes. The human mesenchymal stem cells are derived from human bone marrow.
Abstract translation: 目的：提供促进人类间充质干细胞脂肪细胞分化的组合物，以确保皮肤的体积和弹性，并有效预防或治疗2型糖尿病。构成：用于促进脂肪细胞分化的组合物含有Trichosanthis精液提取物或大麻精液提取物作为活性成分 成分。 用于预防或治疗糖尿病的组合物含有Trichosanthis Semen提取物或大麻精液提取物作为活性成分。 该组合物促进人间充质干细胞向脂肪细胞的分化。 人类间充质干细胞来自人骨髓。
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公开(公告)号：KR1020090126692A
公开(公告)日：2009-12-09
申请号：KR1020080052915
申请日：2008-06-05
Applicant: (주)아모레퍼시픽
IPC: A61K36/185 , A61P3/10 , A61P3/00
Abstract: PURPOSE: A composition for promoting adipocyte differentiation, containing Torreya nucifera extract is provided to use in skin cosmetic or plastic surgery, prevent and treat diabetes. CONSTITUTION: A composition for promoting adipocyte differentiation contains Torreya nucifera extract as an active ingredient. The composition has function of increasing adipose tissue through differentiation of the adipocytes. The adipocyte is differentiated adipocyte from preadipocyte or mesenchymal stem cell of mammal. The mesenchymal stem cell of mammal is human mesenchymal stem cell derived from human bone marrow. The composition increases adipose tissue for skin cosmetic or plastic surgery. The composition is used in preventing or treating diabetes type 2. The daily dose of an active ingredient is 0.0001mg/kg/day~2000g/kg/day.
Abstract translation: 目的：提供用于促进脂肪细胞分化的组合物，其含有Torreya Nucifera提取物用于皮肤美容或整形手术，预防和治疗糖尿病。 构成：用于促进脂肪细胞分化的组合物含有作为活性成分的Torreya Nucifera提取物。 该组合物具有通过脂肪细胞分化增加脂肪组织的功能。 脂肪细胞是哺乳动物前脂肪细胞或间充质干细胞分化的脂肪细胞。 哺乳动物的间充质干细胞来自人骨髓的人间充质干细胞。 组合物增加皮肤美容或整形手术的脂肪组织。 该组合物用于预防或治疗2型糖尿病。活性成分的日剂量为0.0001mg / kg /天〜2000g / kg /天。
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公开(公告)号：KR1020090125948A
公开(公告)日：2009-12-08
申请号：KR1020080052041
申请日：2008-06-03
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K36/74 , A61K2800/92 , A61Q19/08
Abstract: PURPOSE: A composition conaining Oldenlandia diffusa extract for skin cosmetic or beauty as an active ingredient is provided to promote differentiation of human mesenchymal stem cells to adipocytes. CONSTITUTION: A composition for differentiation of adipocyte contains Oldenlandia diffusa extract as an active ingredient. The composition is for increasing adipose tissue. The composition promotes differentiation of human mesenchymal stem cells to adipocyte. The human mesenchymal stem cells are mesenchymal stem cells from human bone marrow. The cosmetic composition is used in the form of massage cream, nutrition cream, pack, and gel.
Abstract translation: 目的：为了促进人类间充质干细胞向脂肪细胞的分化，提供了一种赋予皮肤美容或美容作为活性成分的奥兰达氏锥体提取物的组合物。 构成：用于分化脂肪细胞的组合物含有苦参提取物作为活性成分。 该组合物用于增加脂肪组织。 该组合物促进人间充质干细胞向脂肪细胞的分化。 人类间充质干细胞是人骨髓间充质干细胞。 化妆品组合物以按摩霜，营养霜，包装和凝胶的形式使用。
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