公开(公告)号：KR1020100127728A

公开(公告)日：2010-12-06

申请号：KR1020100049181

申请日：2010-05-26

Applicant: (주)아모레퍼시픽

Inventor： 신현정 ,  김진관 ,  김채욱 ,  주경미 ,  정연수 ,  임경민 ,  서대방 ,  주영협 ,  이상준 ,  박영호

IPC: A61K36/48 ,  A23L1/30 ,  A23L2/52

CPC classification number: A61K36/48 ,  A23L2/52 ,  A23L33/105 ,  A61K2236/333 ,  A23V2200/30

Abstract: PURPOSE: A composition containing soybean extract isolated with low alcohol is provided to improve blood circulation and to treat obesity, diabetes, and hyperlipidemia. CONSTITUTION: A composition for improving blood circulation contains soybean extract isolating with 1-7% of C1-5 alcohol or fraction. The C1-5 alcohol is methanol, ethanol, isopropylalcohol, n-propylalcohol, n-butanol or isobutanol. The soybean extract or fraction contains adenosine. The fraction is an ethylacetate or butanol fraction. The composition suppresses thrombosis or cholesterol generation.

Abstract translation: 目的：提供含有用低分子量分离的大豆提取物的组合物，以改善血液循环和治疗肥胖症，糖尿病和高脂血症。 构成：用于改善血液循环的组合物含有用1-7％的C1-5醇或级分分离的大豆提取物。 C 1-5醇是甲醇，乙醇，异丙醇，正丙醇，正丁醇或异丁醇。 大豆提取物或级分含有腺苷。 馏分是乙酸乙酯或丁醇馏分。 该组合物抑制血栓形成或胆固醇的产生。

公开(公告)号：KR1020100127420A

公开(公告)日：2010-12-06

申请号：KR1020090045858

申请日：2009-05-26

Applicant: (주)아모레퍼시픽

Inventor： 전희영 ,  이지해 ,  주경미 ,  박찬웅 ,  임경민 ,  서대방 ,  이상준

IPC: A61K36/79 ,  A61K36/896 ,  A61K36/258

CPC classification number: A61K36/79 ,  A61K36/258 ,  A61K36/896 ,  A61K2300/00

Abstract: PURPOSE: A ginseng complex composition which enhances the bioavailability of saponin is provided to improve the physiological activity of ginseng saponin. CONSTITUTION: A ginseng complex composition for enhancing the bioavailability of saponiin contains Schisandra chinensis extract or Liriope platyphylla extract and ginseng extract containing saponin. The ginseng extract is ginseng fruit extract. The saponin is ginsenoside Re. A composition for enhancing the bioavailability of saponin contains Schisandra chinensis extract or Liriope platyphylla extract as an active ingredient.

Abstract translation: 目的：提高人参皂苷生理活性，提高皂角苷的生物利用度。 构成：提高saponiin生物利用度的人参复合物组合物含有五味子提取物或Liriope platyphylla提取物和含有皂苷的人参提取物。 人参提取物是人参水果提取物。 皂苷是人参皂甙Re。 用于提高皂角苷生物利用度的组合物含有五味子提取物或Liriope platyphylla提取物作为活性成分。

公开(公告)号：KR100926223B1

公开(公告)日：2009-11-09

申请号：KR1020070120131

申请日：2007-11-23

Applicant: (주)아모레퍼시픽

Inventor： 주경미 ,  박찬웅 ,  정혜진

IPC: G01N30/02 ,  G01N30/00

Abstract: 본 발명은 홍삼의 제조 과정 중 메일러드(Maillard) 반응에 의해 생성되는 2종이상의 아마도리(Amadori) 화합물의 분석법으로서, 홍삼추출물, 홍삼추출물 함유 조성물 또는 혈액 시료 내의 아마도리 화합물인 알기닌-프룩토오스-글루코스(Arg-Fru-Glc) 또는 알기닌-프룩토오스(Arg-Fru)를 이온크로마토그래피의 고정상 및 이동상을 적절하게 선택함으로써 동시에 빠르고 정확하게 분석하는 방법을 개시한다. 상기 동시분석법은 재현성, 정확성, 분석시간, 비용 및 간편성 등에서 이익이 있으므로 홍삼의 품질관리에 응용할 수 있고, 알기닌-프룩토오스(Arg-Fru), 알기닌-프룩토오스-글루코스(Arg-Fru-Glc)를 이용한 약동력학 연구에도 널리 응용할 수 있다. 또한 홍삼이외의 다른 천연추출물이나 혈액이외의 다른 생체시료 내의 물질 분석에도 응용가능하며 유사 아마도리(Amadori) 화합물에도 효과적으로 응용될 것이다.
아마도리 화합물, 이온크로마토그래피(IC), 알기닌-프룩토오스(Arginine-Fructose), 알기닌-프룩토오스-글루코스(Arginine-Fructose-Glucose), 홍삼(Red Ginseng), 혈액

公开(公告)号：KR1020080071633A

公开(公告)日：2008-08-05

申请号：KR1020070009713

申请日：2007-01-31

Applicant: (주)아모레퍼시픽

Inventor： 이소미 ,  김용진 ,  주경미 ,  정혜진

IPC: A61K31/121 ,  A61P17/00

Abstract: A skin external applying composition comprising alpha-keto acid is provided to prevent the keto form of the alpha-keto acid from being converted into a diol form by adjusting a pH thereof more than 6, thereby maximizing the stability of the alpha-keto acid. A skin external applying composition comprises alpha-keto acid stabilized by adding a pH adjusting agent thereto to have a pH of more than 6, wherein the alpha-keto acid is selected from the group consisting of alpha-ketoglutaric acid, oxaloacetic acid, alpha-ketobutyric acid and pyruvic acid.

Abstract translation: 提供包含α-酮酸的皮肤外用施用组合物，以通过调节其大于6的pH来防止α-酮酸的酮形式转化为二醇形式，从而使α-酮酸的稳定性最大化。 皮肤外用施用组合物包含通过向其中加入pH调节剂以使pH大于6而稳定的α-酮酸，其中所述α-酮酸选自α-酮戊二酸，草酰乙酸，α-酮酸， 酮丁酸和丙酮酸。

公开(公告)号：KR100774437B1

公开(公告)日：2007-11-08

申请号：KR1020060113662

申请日：2006-11-17

Applicant: (주)아모레퍼시픽

Inventor： 장희경 ,  김대건 ,  염명훈 ,  최현정 ,  주경미 ,  황재성 ,  안수미

IPC: A61K31/343 ,  A61K8/49 ,  A61Q19/02

CPC classification number: A61K8/4973 ,  A61K31/343 ,  A61Q19/02

Abstract: A skin external composition for skin-whitening containing manassantin B is provided to inhibit mobility of melanin by inhibiting binding of melanophilin as a carrier of melanosome in a melanocyte with myosin 5a, thereby forming melanosome aggregation and whitening the skin. A skin external composition for skin-whitening contains 0.001-10% of manassantin B which is extracted from Saururus chinensis Baill by extracting Saururus chinensis Baill with water or organic solvent selected from ethanol, methanol, butanol, ether, ethylacetate, chloroform and methylene chloride, filtering the extract, concentrating the filtered solution under reduced pressure, extracting the concentrate with methylene chloride and concentrating the extract under reduced pressure, and is formulated as solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation or spray.

Abstract translation: 提供含有马桑丁汀B的皮肤外用组合物，用于通过抑制作为黑素细胞的黑素体的载体的黑色素细胞与肌球蛋白5a的结合来抑制黑色素的迁移，从而形成黑素体聚集并使皮肤变白。 用于皮肤美白的皮肤外用组合物含有0.001-10％的苦参碱B，其通过用水或选自乙醇，甲醇，丁醇，乙醚，乙酸乙酯，氯仿和二氯甲烷的有机溶剂萃取中华白菜， 过滤浓缩滤液，减压浓缩萃取液，减压浓缩，配制成溶液，悬浮液，乳液，糊剂，凝胶，乳液，乳液，粉末，皂，表面活性剂， 含有清洁，油，粉底，乳液粉底，蜡基或喷雾剂。