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公开(公告)号：KR1020140114698A
公开(公告)日：2014-09-29
申请号：KR1020130029390
申请日：2013-03-19
Applicant: 서울대학교산학협력단
IPC: C12Q1/70 , C12Q1/68 , C12N15/11 , G01N33/574
CPC classification number: C12Q1/708 , C12N15/11 , C12Q1/6876 , G01N33/57411
Abstract: The present invention relates to a marker for diagnosing human papillomavirus (HPV) infection or cervical cancer caused by the infection, and a use thereof. More specifically, the present invention relates to a composition for diagnosing HPV infection or cervical cancer caused by the infection, a kit using the same, and a method for the same, which is performed by defecting one or more microorganisms selected from Sneathia, Dialister, and Megasphaera from a testing specimen.
Abstract translation: 本发明涉及用于诊断由感染引起的人乳头瘤病毒（HPV）感染或宫颈癌的标记物及其用途。 更具体地，本发明涉及用于诊断由感染引起的HPV感染或子宫颈癌的组合物，使用该组合物的试剂盒及其方法，其通过缺陷一种或多种选自Sneathia，Dialister， 和Megasphaera从测试样本。
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公开(公告)号：KR101445243B1
公开(公告)日：2014-09-29
申请号：KR1020140037220
申请日：2014-03-28
Applicant: 서울대학교산학협력단
IPC: C12Q1/04 , C12Q1/68 , G01N33/569
CPC classification number: C12Q1/04 , C12Q1/6883 , C12Q1/689 , G01N33/569
Abstract: The present invention relates to a biomarker for risk prediction or diagnosis of metabolic and inflammatory diseases, and use thereof. The biomarker is formulated to detect a group of microorganisms consisting of Akkermansia muciniphila, Bacteroides spp., Eubacterium spp., Roseburia spp., Methanobrevibacter smithii, Methanosphaera stadtmanae, Ruminococcus obeum, and Phascolarctobacterium.
Abstract translation: 本发明涉及用于代谢和炎性疾病的风险预测或诊断的生物标志物及其用途。 配制生物标志物以检测由Akkermansia muciniphila，拟杆菌属，真杆菌属，玫瑰红菌属，甲烷芽孢杆菌属，甲烷球菌属，球形红球菌和Phascolarctobacterium组成的一组微生物。
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公开(公告)号：KR1020100092827A
公开(公告)日：2010-08-23
申请号：KR1020090012145
申请日：2009-02-13
Applicant: 서울대학교산학협력단
CPC classification number: C12N15/11 , C12Q1/6809 , C12Q1/70
Abstract: PURPOSE: A marker for analyzing microorganism contaminant containing a specific sequence of bacteriophage gene is provided to easily trace contamination or/and microorganism contaminant. CONSTITUTION: A marker for analyzing contaminant contains a polynucleotide having base sequence of sequence numbers 1-130 and 267; 50bp or more polynucleotide fragment; or complement of the polynucleotide or polynucleotide fragment. A method for analyzing contaminant comprises: a step of isolating bacteriophage from a sample and analyzing base sequence of gene of the bacteriophage; and a step of measuring relation by comparing polynucleotide having base sequence of sequence numbers 1-261 and 267 or 50bp or more of polynucleotide fragment. The relation is detected by principal component analysis(PCA).
Abstract translation: 目的：提供一种用于分析含有特定噬菌体基因序列的微生物污染物的标记，以便于追踪污染物和/或微生物污染物。 构成：用于分析污染物的标记物含有具有序列号1-130和267的碱基序列的多核苷酸; 50bp或更多个多核苷酸片段; 或多核苷酸或多核苷酸片段的互补序列。 分析污染物的方法包括：从样品中分离噬菌体并分析噬菌体基因的碱基序列的步骤; 以及通过比较具有序列号1-261和267的碱基序列或50bp或更多个多核苷酸片段的多核苷酸来测量关系的步骤。 该关系由主成分分析（PCA）检测。
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公开(公告)号：KR1020090078136A
公开(公告)日：2009-07-17
申请号：KR1020080003944
申请日：2008-01-14
Applicant: 서울대학교산학협력단 , 한국외국어대학교 연구산학협력단
CPC classification number: C12M47/02 , G01N1/4077
Abstract: A collection and detection method of microorganism in food through ultrafiltration is provided to analyze various kinds of microorganism in a small amount of sample and reduce time and expense for analysis of microorganism. A microorganism in food is collected and concentrated through ultrafiltration using hollow-fiber. The hollow-fiber is pretreated with bovine calf serum, NaPP, glycine-added FBS, beef extract, bovine serum albumin (BSA), or nutrient broth blocking solution. The microorganism is bacteriophage, virus, germ, prokaryote or spore. The virus is rotavirus or noroviurs. The microorganism is detected by using PCR (polymerase chain reaction) of collected and concentrated microorganism sample.
Abstract translation: 提供超滤食品中微生物的收集和检测方法，以分析少量样品中的各种微生物，并减少微生物分析的时间和费用。 通过使用中空纤维的超滤收集食物中的微生物并浓缩。 中空纤维用牛血清，NaPP，加入甘氨酸的FBS，牛肉提取物，牛血清白蛋白（BSA）或营养液阻断溶液预处理。 微生物是噬菌体，病毒，胚芽，原核生物或孢子。 病毒是轮状病毒或诺维诺病毒。 通过使用收集和浓缩的微生物样品的PCR（聚合酶链式反应）检测微生物。
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