中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

47 records (took 0.027 seconds)

    METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY
    31.
    发明公开
    METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY 审中-公开
    检测生物活性的方法和组合物

    公开(公告)号：EP3269822A1

    公开(公告)日：2018-01-17

    申请号：EP17188383.8

    申请日：2011-10-28

    Applicant: 3M Innovative Properties Company

    Inventor： ROSCOE, Stephen B. ,  HALVERSON, Kurt J. ,  MILLER, Jesse D. ,  MOELLER, Stephanie J. ,  BJORK, Jason W.

    IPC: C12Q1/04 ,  G01N21/64

    Abstract: A method of detecting a biological activity, comprising: providing, a sample that may comprise a first biological activity; a first indicator reagent that can be converted by the first biological activity to a first biological derivative; a gelling agent; and a plurality of particles, each particle comprising an organic polymer that receives and retains the first biological derivative, wherein the particles have a mean particle diameter between 0.05 microns and 20 microns; forming a hydrogel comprising the first indicator reagent and the plurality of particles; wherein at least a portion of the plurality of particles is dispersed in the hydrogel or disposed on a major surface of the hydrogel; bringing the sample into fluid communication with a portion of the hydrogel; and detecting the presence or absence of the first biological derivative, wherein the first biological derivative is retained by the plurality of particles; wherein detecting the presence or absence of the first biological derivative comprises detecting a fluorescent first biological derivative or a colored first biological derivative; and wherein the presence of the first biological derivative is indicative of the presence of a first biological activity.

    Abstract translation: 一种检测生物活性的方法，包括：提供可包含第一生物活性的样品; 可以通过第一生物活性转化成第一生物衍生物的第一指示剂; 胶凝剂; 和多个颗粒，每个颗粒包含接收并保留第一生物衍生物的有机聚合物，其中所述颗粒具有0.05微米至20微米的平均粒径; 形成包含所述第一指示剂和所述多个颗粒的水凝胶; 其中所述多个颗粒的至少一部分分散在所述水凝胶中或设置在所述水凝胶的主表面上; 使样品与一部分水凝胶流体连通; 并检测第一生物衍生物的存在或不存在，其中第一生物衍生物被多个颗粒保留; 其中检测所述第一生物衍生物的存在或不存在包括检测荧光第一生物衍生物或有色第一生物衍生物; 并且其中第一生物衍生物的存在指示存在第一生物活性。

    CAP HANDLING TOOLS AND METHODS OF USE
    32.
    发明公开
    CAP HANDLING TOOLS AND METHODS OF USE 审中-公开
    KAPPENHANDHABUNGSWERKZEUGE UND VERWENDUNGSVERFAHREN

    公开(公告)号：EP2739437A1

    公开(公告)日：2014-06-11

    申请号：EP12748091.1

    申请日：2012-08-02

    Applicant: 3M Innovative Properties Company

    Inventor： BARTHOLOMEW, Cheryl A. ,  BJORK, Jason W. ,  PERCY, Neil ,  SITTON, Gregory W.

    IPC: B25B9/00 ,  B01L9/00 ,  B01L99/00

    Abstract: Tools (100) are provided for use in uncapping one or more of a plurality of linearly-oriented, spaced-apart tubes; each cap having a cap upper surface with a depression. The tools comprise a body (30) having first portion (40) for engagement by a user and a second portion (50) for engaging a plurality of caps. The second portion comprises a plurality of spaced-apart projections (60). Each projection is configured for releasably engaging a cap. The projection may comprise two or more spaced-apart projection elements (62,64). Optionally, the first portion is configured in a non-coplanar relationship with respect to the second portion. Methods of use are also provided.

    Abstract translation: 工具（100）被提供用于开启多个线性取向的间隔开的管中的一个或多个管; 每个盖具有带有凹陷的盖上表面。 工具包括具有用于与使用者接合的第一部分（40）和用于接合多个盖的第二部分（50）的主体（30）。 第二部分包括多个间隔开的突起（60）。 每个突起构造成可释放地接合盖。 突起可以包括两个或更多个间隔开的投影元件（62,64）。 可选地，第一部分被配置成相对于第二部分的非共面关系。 还提供了使用方法。

Patent Agency Ranking