公开(公告)号：DK303278A

公开(公告)日：1979-01-07

申请号：DK303278

申请日：1978-07-05

Applicant: BASF AG

Inventor： SCHARWAECHTER P ,  GUTSCHE K ,  KOHLMANN W ,  KROEMER G

IPC: A61K31/505 ,  A61P31/04 ,  A61P33/02 ,  C07D239/48 ,  C07D239/49 ,  C07D

Abstract: Unsubstituted or substituted 5-phenyl- and 5-benzyl-4-amino-pyrimidine-2-imidoacid esters, their preparation, drugs containing these compounds, and their use in infectious diseases.

公开(公告)号：ZA818370B

公开(公告)日：1982-11-24

申请号：ZA818370

申请日：1981-12-03

Applicant: BASF AG

Inventor： SCHARWAECHTER P ,  GUTSCHE K ,  KOHLMANN F ,  BECK H

IPC: A61K31/505 ,  A61K31/63 ,  A61K31/635 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49 ,  C07D

Abstract: 2-Carbamic acid esters of 2,4-diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidine (trimethoprim), a process for their preparation, and drugs containing these compounds, which, as pro-drugs of trimethoprim, have valuable antibacterial properties and potentiate the antibacterial action of sulfonamides.

公开(公告)号：IN149577B

公开(公告)日：1982-01-30

申请号：IN747CA1978

申请日：1978-07-06

Applicant: BASF AG

Inventor： KOHLMANN W ,  GUTSCHE K ,  KROEMER H ,  SCHARWAECHTER P ,  KROEMER N ,  KROEMER M

IPC: A61K31/505 ,  A61K31/535 ,  A61P31/04 ,  A61P33/02 ,  C07D239/48 ,  C07D239/49 ,  C07D403/12 ,  C07D413/12 ,  C07D51/42 ,  A61K27/00

公开(公告)号：IN149534B

公开(公告)日：1982-01-09

申请号：IN203CA1978

申请日：1978-02-23

Applicant: BASF AG

Inventor： GUTSCHE K ,  SCHARWAECHTER P ,  KOHLMANN F

IPC: A61K31/505 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49 ,  C07D51/36

Abstract: 2-Acylamino-4-amino-5-benzylpyrimidines substituted in the phenyl ring of the benzyl radical, their production and their use as sulfonamide potentiators, as well as agents containing the same, are disclosed. The compounds 4-amino-2-formamido-5-(3,4,5-trimethoxybenzyl)-pyrimidine and 4-amino-2-acetamido-5-(3,4,5-trimethoxybenzyl)-pyrimidine are examples of the subject pyrimidines.

公开(公告)号：DK143273B

公开(公告)日：1981-08-03

申请号：DK315878

申请日：1978-07-14

Applicant: BASF AG

Inventor： SCHARWAECHTER P ,  GUTSCHE K ,  KOHLMANN F-W ,  KROEMER G

IPC: A61K31/505 ,  C07D239/48 ,  C07D239/49 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12 ,  C07D239/69

公开(公告)号：DK142577C

公开(公告)日：1981-07-20

申请号：DK303278

申请日：1978-07-05

Applicant: BASF AG

Inventor： SCHARWAECHTER P ,  GUTSCHE K ,  KOHLMANN F-W ,  KROEMER G

IPC: A61K31/505 ,  A61P31/04 ,  A61P33/02 ,  C07D239/48 ,  C07D239/49

Abstract: Unsubstituted or substituted 5-phenyl- and 5-benzyl-4-amino-pyrimidine-2-imidoacid esters, their preparation, drugs containing these compounds, and their use in infectious diseases.

公开(公告)号：ZA784012B

公开(公告)日：1979-08-29

申请号：ZA784012

申请日：1978-07-14

Applicant: BASF AG

Inventor： KROEMER G ,  SCHARWAECHTER P ,  KOHLMANN W ,  GUTSCHE K

IPC: A61K31/505 ,  C07D239/48 ,  C07D239/49 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12 ,  C07D

公开(公告)号：ZA783874B

公开(公告)日：1979-08-29

申请号：ZA783874

申请日：1978-07-05

Applicant: BASF AG

Inventor： KROEMER G ,  GUTSCHE K ,  SCHARWAECHTER P ,  KOHLMANN W

IPC: A61K31/505 ,  A61P31/04 ,  A61P33/02 ,  C07D239/48 ,  C07D239/49 ,  C07D ,  A61K

Abstract: Unsubstituted or substituted 5-phenyl- and 5-benzyl-4-amino-pyrimidine-2-imidoacid esters, their preparation, drugs containing these compounds, and their use in infectious diseases.

公开(公告)号：ZA7803874B

公开(公告)日：1979-08-29

申请号：ZA7803874

申请日：1978-07-05

Applicant: BASF AG

Inventor： KROEMER G ,  GUTSCHE K ,  SCHARWAECHTER P ,  KOHLMANN W

IPC: A61K31/505 ,  A61P31/04 ,  A61P33/02 ,  C07D239/48 ,  C07D239/49 ,  C07D ,  A61K

CPC classification number: C07D239/48 ,  C07D239/49

公开(公告)号：ZA781242B

公开(公告)日：1979-03-28

申请号：ZA781242

申请日：1978-03-03

Applicant: BASF AG

Inventor： GUTSCHE K ,  KOHLMANN F ,  SCHARWAECHTER P

IPC: A61K31/505 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49

Abstract: 2-Acylamino-4-amino-5-benzylpyrimidines substituted in the phenyl ring of the benzyl radical, their production and their use as sulfonamide potentiators, as well as agents containing the same, are disclosed. The compounds 4-amino-2-formamido-5-(3,4,5-trimethoxybenzyl)-pyrimidine and 4-amino-2-acetamido-5-(3,4,5-trimethoxybenzyl)-pyrimidine are examples of the subject pyrimidines.