公开(公告)号：US11257967B2

公开(公告)日：2022-02-22

申请号：US16504868

申请日：2019-07-08

Applicant: NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)

Inventor： Helge Weman ,  Bjørn-Ove Fimland ,  Dong Chul Kim

IPC: H01L31/0352 ,  H01L31/0304 ,  H01L31/18 ,  H01L31/0224

Abstract: A composition of matter, in particular a photovoltaic cell, comprising: at least one core semiconductor nanowire on a graphitic substrate, said at least one core nanowire having been grown epitaxially on said substrate wherein said nanowire comprises at least one group III-V compound or at least one group II-VI compound or at least one group IV element; a semiconductor shell surrounding said core nanowire, said shell comprising at least one group III-V compound or at least one group II-VI compound or at least one group IV element such that said core nanowire and said shell form a n-type semiconductor and a p-type semiconductor respectively or vice versa; and an outer conducting coating surrounding said shell which forms an electrode contact.

公开(公告)号：US20210322107A1

公开(公告)日：2021-10-21

申请号：US17272451

申请日：2019-09-13

Applicant: Norwegian University of Science and Technology (NTNU)

Inventor： Daniel Fossum Bratbak

IPC: A61B34/20 ,  G06T7/73

Abstract: A method of calibrating an instrument for surgical intervention is provided. The instrument to be calibrated has a tip at a distal end thereof and a navigation array that is spaced from the distal end and is detectable in space. The navigation array has a fixed spatial and angular relationship with the tip. The method comprises the steps of: placing a calibrator on the tip of the instrument such that the tip is positioned within the calibrator at a known displacement from the centre of the calibrator, the calibrator having a circular shape and being detectable as a single point in space; detecting the position of the navigation array and the centre of the calibrator; and determining the position of the centre of the calibrator relative to the navigation array, thereby calibrating the position of the tip of the instrument relative to the navigation array. There is also provided a calibrator for use in such a method.

公开(公告)号：US10861696B2

公开(公告)日：2020-12-08

申请号：US15971278

申请日：2018-05-04

Applicant: NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Helge Weman ,  Bjørn-Ove Fimland ,  Dong Chul Kim

IPC: H01L21/02 ,  B82Y40/00 ,  H01L29/06 ,  B82Y30/00 ,  B82Y10/00 ,  H01L29/16

Abstract: A composition of matter comprising at least one nanowire on a graphitic substrate, said at least one nanowire having been grown epitaxially on said substrate, wherein said nanowire comprises at least one group III-V compound or at least one group II-VI compound or comprises at least one non carbon group (IV) element.

公开(公告)号：US10517923B2

公开(公告)日：2019-12-31

申请号：US15034917

申请日：2014-11-06

Applicant: NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)

Inventor： Marit Otterlei

IPC: A61K38/05 ,  A61K47/64 ,  A61K38/17 ,  A61K38/08 ,  A61K45/06

Abstract: The present invention provides an agent, or composition containing an agent, for use in treating or preventing hypercytokinemia in a subject resulting from cytokine release from non-proliferating immune cells in blood, wherein the agent comprises: (i) an oligopeptidic compound comprising a PCNA interacting motif and a domain that facilitates the cellular uptake of said compound, wherein the PCNA interacting motif is X1X2X3X4X5 (SEQ ID NO: 1) and wherein: X1 is a basic amino acid; X2 is an aromatic amino acid; X3 is an uncharged amino acid other than an aromatic amino acid, Glycine (G) and Proline (P); X4 is any amino acid other than Proline (P), an acidic amino acid or an aromatic amino acid; and X5 is a basic amino acid or Proline (P); or (ii) a nucleic acid molecule comprising a sequence encoding the oligopeptidic compound of (i). In certain aspects the agent and compositions of the invention may be used as single agents. In other aspects of the invention agents and compositions of the invention may be used in conjunction with one or more additional active agents, such as kinase inhibitors.

公开(公告)号：US10450348B2

公开(公告)日：2019-10-22

申请号：US15034948

申请日：2014-11-06

Applicant: Norwegian University of Science and Technology

Inventor： Marit Otterlei ,  Siri Bachke

IPC: A01N37/18 ,  A61K38/00 ,  A61P31/04 ,  A61K38/04 ,  C07K5/00 ,  C07K7/00 ,  C07K16/00 ,  C07K17/00 ,  C07K14/00 ,  A61K38/17 ,  A01N25/08 ,  A01N63/02 ,  A61K31/165 ,  A61K31/35 ,  A61K31/397 ,  A61K31/43 ,  A61K31/496 ,  A61K31/7036 ,  A61K31/7048 ,  A61K38/14 ,  A61K38/16 ,  A61K41/00 ,  A61K45/06 ,  A61L2/10 ,  A61L2/16

Abstract: The present invention provides an agent, or a composition containing an agent, for use in treating or preventing a bacterial infection in a subject, wherein said agent comprises: (i) an oligopeptidic compound comprising a PCNA interacting motif and a domain that facilitates the cellular uptake of said compound, wherein the PCNA interacting motif is X1X2X3X4X5 (SEQ ID NO: 1) and wherein: X1 is a basic amino acid; X2 is an aromatic amino acid; X3 is an uncharged amino acid other than an aromatic amino acid, Glycine (G) and Proline (P); X4 is any amino acid other than Proline (P), an acidic amino acid or an aromatic amino acid; and X5 is a basic amino acid or Proline (P); or (ii) a nucleic acid molecule comprising a sequence encoding the oligopeptidic compound of (i). In certain aspects the agent and compositions of the invention may be used as single agents. In other aspects of the invention agents and compositions of the invention may be used in conjunction with one or more additional active agents, such as antibiotics.

公开(公告)号：US10243104B2

公开(公告)日：2019-03-26

申请号：US14371621

申请日：2013-01-10

Applicant: NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)

Inventor： Helge Weman ,  Bjørn-Ove Fimland ,  Dong Chul Kim

IPC: H01L33/24 ,  H01L21/02 ,  H01L21/203 ,  H01L21/205 ,  H01L21/20 ,  H01L21/208 ,  H01L29/06 ,  B82Y10/00 ,  B82Y40/00 ,  H01L29/66 ,  H01L29/16 ,  H01L29/41 ,  C30B25/00 ,  C30B29/42 ,  H01L31/0224 ,  H01L31/0304 ,  H01L31/0352 ,  H01L31/036 ,  H01L31/18 ,  H01L33/00 ,  H01L33/18 ,  H01L33/30 ,  H01L33/42

Abstract: A composition of matter comprising a plurality of nanowires on a substrate, said nanowires having been grown epitaxially on said substrate in the presence of a metal catalyst such that a catalyst deposit is located at the top of at least some of said nanowires, wherein said nanowires comprise at least one group III-V compound or at least one group II-VI compound or comprises at least one non carbon group IV element; and wherein a graphitic layer is in contact with at least some of the catalyst deposits on top of said nanowires.

公开(公告)号：US10082127B2

公开(公告)日：2018-09-25

申请号：US15111659

申请日：2015-01-16

Applicant: Norwegian University of Science and Technology

Inventor： Jørgen Hals Todalshaug

IPC: F03B13/20 ,  F03B13/16 ,  F03B13/18

CPC classification number: F03B13/181 ,  F03B13/1845 ,  F03B13/1885 ,  F03B13/1895 ,  F03B13/20 ,  F05B2260/502 ,  Y02E10/38

Abstract: A wave energy convertor for extracting energy from ocean waves. The wave energy convertor may include a buoy arranged to oscillate relative to a reference point about an equilibrium position and a negative spring device connected between the buoy and the reference point, wherein the negative spring device is for applying a positive force in the direction of displacement when the buoy moves away from the equilibrium position.

公开(公告)号：US20180254184A1

公开(公告)日：2018-09-06

申请号：US15971278

申请日：2018-05-04

Applicant: NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Helge Weman ,  Bjørn-Ove Fimland ,  Dong Chul Kim

IPC: H01L21/02 ,  H01L29/06 ,  B82Y10/00 ,  B82Y40/00 ,  B82Y30/00 ,  H01L29/16

CPC classification number: H01L21/02603 ,  B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  H01L21/02376 ,  H01L21/02538 ,  H01L21/02551 ,  H01L21/02631 ,  H01L21/02645 ,  H01L21/02653 ,  H01L29/0676 ,  H01L29/1606

Abstract: A composition of matter comprising at least one nanowire on a graphitic substrate, said at least one nanowire having been grown epitaxially on said substrate, wherein said nanowire comprises at least one group III-V compound or at least one group II-VI compound or comprises at least one non carbon group (IV) element.

公开(公告)号：US20180000553A1

公开(公告)日：2018-01-04

申请号：US15537313

申请日：2015-12-16

Applicant: Norwegian University of Science and Technology

Inventor： Daniel Fossum Bratbak

IPC: A61B90/11 ,  A61B34/20 ,  A61B17/34 ,  A61B90/16 ,  A61B90/00

CPC classification number: A61B90/11 ,  A61B17/3403 ,  A61B17/3472 ,  A61B34/20 ,  A61B90/16 ,  A61B2017/3407 ,  A61B2034/108 ,  A61B2034/2057 ,  A61B2090/363 ,  A61B2090/3983

Abstract: A guidance device for guidance of surgical interventions on a patient, the surgical interventions requiring an intervention device to surgically enter the body and be directed through body tissues to a target site within the patient's head, the guidance device comprising: a guide piece 4 for guiding the intervention device and directing it to the target site within the patient's head; a mouthpiece 2 arranged to anchor the device in a fixed orientation relative to the patient's upper jaw or lower jaw; and a targeted or targetable mounting 6 supporting the guide piece on the mouthpiece, the mounting 6 being for directing the guide piece 4 in a desired orientation relative to the mouthpiece 2 to thereby direct the intervention device through body tissues to the target site in the patient's head.

公开(公告)号：US20170107294A1

公开(公告)日：2017-04-20

申请号：US15126938

申请日：2014-03-21

Applicant: Nordlandssykehuset HF ,  Norwegian University of Science and Technology CO/ NTNU Technology Transfer AS ,  University of Oslo

Inventor： Terje Espevik ,  Tom Eirik Mollnes ,  Inger Sandlie ,  Corinna Lau ,  Kristin S. Gunnarsen

IPC: C07K16/28 ,  A61K45/06 ,  A61K39/395 ,  C07K14/765

CPC classification number: C07K16/2896 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  C07K14/765 ,  C07K2317/24 ,  C07K2317/52 ,  C07K2317/56 ,  C07K2317/71 ,  C07K2317/76 ,  C07K2319/31

Abstract: The present invention relates to chimeric anti-CD14 antibodies and methods of using the same. In some embodiments, the present invention relates to the use of chimieric anti-CD 14 antibodies in research, diagnostic, and therapeutic applications. In one embodiment, the anti-CD14 antibody has a variable light chain of SEQ ID NO: 1 and a variable heavy chain of SEQ ID NO: 2 (isolated from the hybridoma clone 18D11). In another embodiment, the anti-CD14 antibody has a variable light chain of SEQ ID NO: 3 and a variable heavy chain of SEQ ID NO: 4 (isolated from the hybridoma clone Mil2).