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    ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF SERTRALINE
    41.
    发明申请
    ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF SERTRALINE 审中-公开
    口服液体药物组合物

    公开(公告)号：WO2005034910A1

    公开(公告)日：2005-04-21

    申请号：PCT/IB2004/003272

    申请日：2004-10-07

    Applicant: RANBAXY LABORATORIES LIMITED ,  RAHEJA, Praveen ,  ISLOOR, Shashikanth ,  SETHI, Sanjeev, Kumar

    Inventor： RAHEJA, Praveen ,  ISLOOR, Shashikanth ,  SETHI, Sanjeev, Kumar

    IPC: A61K9/00

    CPC classification number: A61K9/0095 ,  A61K31/135

    Abstract: The present invention relates to oral liquid pharmaceutical compositions that include sertraline. The invention also relates to processes for the preparation of the pharmaceutical compositions and their use in treating medical conditions. The oral liquid pharmaceutical composition includes sertraline or a pharmaceutically acceptable salt thereof and water. The water is present at an amount that is greater than about 10% w/w to about 40% w/w of the composition.

    Abstract translation: 本发明涉及包含舍曲林的口服液体药物组合物。 本发明还涉及药物组合物的制备方法及其在治疗病症中的用途。 口服液体药物组合物包括舍曲林或其药学上可接受的盐和水。 水的含量大于组合物的约10％w / w至约40％w / w。

    PROCESS FOR PREPARING AN INTERMEDIATE OF SITAGLIPTIN VIA ENZYMATIC CONVERSION
    44.
    发明申请
    PROCESS FOR PREPARING AN INTERMEDIATE OF SITAGLIPTIN VIA ENZYMATIC CONVERSION 审中-公开
    通过酶转化制备西他汀的中间体的方法

    公开(公告)号：WO2012046254A3

    公开(公告)日：2012-06-07

    申请号：PCT/IN2011000702

    申请日：2011-10-10

    Applicant: CADILA HEALTHCARE LTD ,  MENDIRATTA SANJEEV KUMAR ,  PANDEY BIPIN ,  JOSHI RUPAL ,  TRIVEDI UMANG ,  DAVE MAYANK G ,  KOTHARI HIMANSHU M ,  SHUKLA BHAVIN

    Inventor： MENDIRATTA SANJEEV KUMAR ,  PANDEY BIPIN ,  JOSHI RUPAL ,  TRIVEDI UMANG ,  DAVE MAYANK G ,  KOTHARI HIMANSHU M ,  SHUKLA BHAVIN

    IPC: C07D487/04 ,  C12N9/02 ,  C12P17/18

    CPC classification number: C07D487/04 ,  C12N9/0004 ,  C12P17/182 ,  C12P41/002 ,  C12R1/19

    Abstract: The invention provides a process for preparing 3 -hydroxy-1-(3- (trifluoromethyl)-5,6-dihydro-[l,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl) butan-1-one (Formula I), into its racemic (R/S) form or any of its optically active (S) or (R) forms or enantiomeric excess mixture of any of the forms comprising: a) reacting 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1- (2,4,5-trifluorophenyl)butan-2-one of formula (III) with a suitable oxidoreductase enzymes or its suitable variants in the presence of suitable conditions and co-factor b) isolating 3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl)-4-(2,4,5-trifluorophenyl) butan-1-one, into its racemic (R/S) form or any of its optically active (S) or (R) forms or enantiomeric excess mixture of any of the forms

    Abstract translation: 本发明提供了制备3-羟基-1-（3-（三氟甲基）-5,6-二氢 - [1,2,4]三唑并[4,3-a]吡嗪-7（8H） - 基） -4-（2,4,5-三氟苯基）丁-1-酮（式I）转化成其外消旋（R / S）形式或其任何光学活性（S）或（R）形式或对映体过量混合物 任何形式包括：a）使4-氧代-4- [3-（三氟甲基）-5,6-二氢[1,2,4]三唑并[4,3-a]吡嗪-7（8H） - 基 ] - （2,4,5-三氟苯基）丁-2-酮与合适的氧化还原酶或其合适的变体在合适的条件和辅因子存在下b）分离3-羟基-1 - （3-（三氟甲基）-5,6-二氢 - [1,2,4]三唑并[4,3-a]吡嗪-7（8H） - 基）-4-（2,4,5-三氟苯基） （R / S）形式或其任何形式的任何光学活性（S）或（R）形式或对映异构体过量混合物

    HIGH GAIN, HIGH FREQUENCY CMOS OSCILLATOR CIRCUIT AND METHOD
    49.
    发明申请
    HIGH GAIN, HIGH FREQUENCY CMOS OSCILLATOR CIRCUIT AND METHOD 审中-公开
    高增益，高频CMOS振荡器电路和方法

    公开(公告)号：WO2007095451B1

    公开(公告)日：2007-10-11

    申请号：PCT/US2007061857

    申请日：2007-02-08

    Applicant: CYPRESS SEMICONDUCTOR CORP ,  MAHESHWARI SANJEEV KUMAR

    Inventor： MAHESHWARI SANJEEV KUMAR

    IPC: H03B5/36

    CPC classification number: H03B5/364 ,  H03B2200/0062

    Abstract: An oscillator amplifier circuit is provided. The amplifier circuit can be used with a resonator to amplify and form a resonating oscillator. The amplifier circuit comprises an active circuit which includes an inverter and a current-controlled biasing circuit. One transistor of the inverter receives a voltage produced from the biasing circuit in order to place a gate terminal of that transistor at approximately a threshold voltage. The other transistor can be biased using a passive circuit element, such as a resistor. Therefore, both transistors are biased independent of each other within the optimal gain region. Large shunt capacitors are not required and the total current consumption is controlled through a variable resistor coupled to the source terminal of either the first transistor, second transistor, or possibly both transistors of the inverter to adjust the amplitude of the oscillating output.

    Abstract translation: 提供振荡器放大器电路。 放大器电路可以与谐振器一起使用来放大并形成谐振振荡器。 放大器电路包括有源电路，该有源电路包括反相器和电流控制的偏置电路。 反相器的一个晶体管接收由偏置电路产生的电压，以便将该晶体管的栅极端子置于近似阈值电压。 另一个晶体管可以使用诸如电阻的无源电路元件进行偏置。 因此，两个晶体管在最佳增益区内彼此独立偏置。 不需要大并联电容器，并且总电流消耗通过耦合到第一晶体管，第二晶体管或可能两个晶体管的源极端子的可变电阻器来控制，以调整振荡输出的振幅。

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