中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

119 records (took 0.043 seconds)

    QUALITY CONTROL OF DIAMAGNETIC MATERIALS USING MAGNETIC LEVITATION
    42.
    发明申请
    QUALITY CONTROL OF DIAMAGNETIC MATERIALS USING MAGNETIC LEVITATION 审中-公开
    使用磁性检测的钻孔材料的质量控制

    公开(公告)号：WO2012075009A1

    公开(公告)日：2012-06-07

    申请号：PCT/US2011/062399

    申请日：2011-11-29

    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE ,  TRICARD, Simon ,  ELLERBEE, Audrey ,  WHITESIDES, George, M.

    Inventor： TRICARD, Simon ,  ELLERBEE, Audrey ,  WHITESIDES, George, M.

    IPC: G01R33/12

    CPC classification number: G01N27/72 ,  G01R33/1269 ,  G01R33/1276

    Abstract: The ability to levitate and detect height and orientation of diamagnetic objects suspended in paramagnetic solutions using an inhomogeneous magnetic field is described. By comparing the measured height and orientation of a sample material with the measured height and orientation of a reference material, quality control of objects can be carried out. The major advantages of this quality control technique are: i) it is a simple apparatus that does not require electric power (a set of permanent magnets and gravity are sufficient for the diamagnetic separation and collection system to work); ii) it is compatible with simple optical detection; iii) it is a cost-effective and simple method that can carry out quality control between sample and reference materials rapidly.

    Abstract translation: 描述了使用非均匀磁场悬浮和检测悬浮在顺磁性溶液中的抗磁性物体的高度和取向的能力。 通过将样品材料的测量高度和取向与测量的参考材料的高度和取向相比较，可以进行物体的质量控制。 这种质量控制技术的主要优点是：i）不需要电力的简单设备（一组永磁体和重力足以使反磁性分离和收集系统工作）; ii）与简单的光学检测兼容; iii）可以快速，高效地进行样品和参比物质的质量控制。

    ALGINATE HYDROGEL FIBERS AND RELATED MATERIALS
    45.
    发明申请
    ALGINATE HYDROGEL FIBERS AND RELATED MATERIALS 审中-公开
    ALGINATE HYDROGEL FIBERS和相关材料

    公开(公告)号：WO2012009363A1

    公开(公告)日：2012-01-19

    申请号：PCT/US2011/043718

    申请日：2011-07-12

    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE ,  MACE, Charles, R. ,  BARBER, Jabulani ,  LAROMAINE SAGUĖ, Anna ,  WHITESIDES, George, M. ,  CADEMARTIRI, Rebecca

    Inventor： MACE, Charles, R. ,  BARBER, Jabulani ,  LAROMAINE SAGUĖ, Anna ,  WHITESIDES, George, M. ,  CADEMARTIRI, Rebecca

    IPC: C12N5/00

    CPC classification number: C12N5/0062 ,  C12N5/0068 ,  C12N2533/30 ,  C12N2533/56 ,  C12N2533/74 ,  D01D5/40 ,  D01F9/04

    Abstract: Alginate hydrogel fibers and related materials as well as methods for preparing such materials are provided. An alginate hydrogel fiber includes water in an amount of more than about 92% by weight of the fiber and a cross-linked alginate in an amount of about 0.1% to about 8% by weight of the fiber, wherein the cross-link is a cation. An alginate hydrogel paper includes one or more alginate hydrogel fibers, which form a non-woven matrix. Three- dimensional cellular arrays are also provided, wherein the alginate hydrogel making up the alginate paper is substantially index-matched with a predetermined culture medium. A method for making alginate hydrogel fiber and a method for index-matching alginate hydrogel paper with culture medium are provided. A kit for conducting biochemical, diagnostic, cellular, and/or non-cellular analysis comprises alginate hydrogel paper index-matched to culture medium.

    Abstract translation: 提供藻酸盐水凝胶纤维及相关材料以及制备这些材料的方法。 藻酸盐水凝胶纤维包含水量大于纤维重量的约92％，交联藻酸盐的量为纤维重量的约0.1％至约8％，其中交联是 阳离子。 藻酸盐水凝胶纸包括形成非织造基质的一种或多种藻酸盐水凝胶纤维。 还提供了三维细胞阵列，其中构成藻酸盐纸的藻酸盐水凝胶与预定的培养基基本上是指数匹配的。 提供了藻酸盐水凝胶纤维的制备方法和藻酸盐水凝胶纸与培养基的折射率匹配方法。 用于进行生化，诊断，细胞和/或非细胞分析的试剂盒包括与培养基指数匹配的藻酸盐水凝胶纸。

    SYNTHETIC TRIVALENT HAPTENS, COMPLEXES THEREOF, AND USES THEREFOR
    50.
    发明申请
    SYNTHETIC TRIVALENT HAPTENS, COMPLEXES THEREOF, AND USES THEREFOR 审中-公开
    合成TRIVALENT HAPTENS，其复合物及其用途

    公开(公告)号：WO2008140595A2

    公开(公告)日：2008-11-20

    申请号：PCT/US2007/086163

    申请日：2007-11-30

    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE ,  BILGICER, Zihni, Basar ,  MOUSTAKAS, Demetri, T. ,  WHITESIDES, George, M.

    Inventor： BILGICER, Zihni, Basar ,  MOUSTAKAS, Demetri, T. ,  WHITESIDES, George, M.

    IPC: G01N33/531 ,  G01N33/53 ,  A61K47/48 ,  G01N33/543

    CPC classification number: G01N33/531 ,  A61K47/646

    Abstract: The invention provides trivalent hapten molecules (trihapten molecules) and complexes thereof. The trivalent hapten molecules are useful for forming relatively stable complexes comprising hapten molecules and divalent ligands (e.g., antibodies) for the hapten molecules. Such trihapten molecules are useful for assays, e.g., of antibodies, or for depleting a ligand from a sample, e.g., for treating a disease by binding an undesirable receptor such as an antibody. Complexes of trivalent hapten molecules are useful for selectively targeting relatively high density, multivalent presentations of haptens, such as occur on cells overexpressing a molecule on their surfaces, such as cancer cells.

    Abstract translation: 本发明提供三价半抗原分子（trihapten分子）及其复合物。 三价半抗原分子可用于形成包含用于半抗原分子的半抗原分子和二价配体（例如抗体）的相对稳定的复合物。 这种三阴离子分子可用于例如抗体的测定，或用于从样品中消耗配体，例如通过结合不期望的受体例如抗体来治疗疾病。 三价半抗原分子的复合物可用于选择性靶向半抗原的相对高密度多价表现，例如在其表面上的分子例如癌细胞上发生的细胞上发生。

Patent Agency Ranking