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公开(公告)号：KR1020110081462A
公开(公告)日：2011-07-14
申请号：KR1020100001645
申请日：2010-01-08
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A method for apparatus for evaluating skin sensitization on a material is provided to measure absorbance or fluorescence without pretreatment. CONSTITUTION: A method for evaluating skin sensitization on a test material comprises: a step of reacting a peptide and the material to prepare a reactant; a step of treating the reactant with a reagent and measuring absorbance and fluorescence; and a step of evaluating skin sensitization positive according to the reaction degree. The peptide is a synthetic peptide containing cysteine or lysine. The reagent is used for detecting one or more of -SH group and -NH_2 group. The material is a cosmetic composition.
Abstract translation: 目的：提供一种用于评价材料上的皮肤敏化的装置的方法，以在没有预处理的情况下测量吸光度或荧光。 构成：用于评估测试材料上的皮肤致敏的方法包括：使肽和所述材料反应以制备反应物的步骤; 用试剂处理反应物并测量吸光度和荧光的步骤; 以及根据反应程度评价皮肤致敏阳性的步骤。 肽是含有半胱氨酸或赖氨酸的合成肽。 该试剂用于检测-SH基团和-NH 2基团中的一个或多个。 该材料是化妆品组合物。
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公开(公告)号：KR1020110013126A
公开(公告)日：2011-02-09
申请号：KR1020090096071
申请日：2009-10-09
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K9/0014 , A61K36/53 , A61K36/752 , Y10S514/844 , Y10S514/857 , Y10S514/886
Abstract: PURPOSE: A composition containing Glechoma hederacera extract or Boerhavia diffusa extract for relieving skin irritation or inflammation is provided to be used in cosmetic or pharmaceutical field. CONSTITUTION: A composition for relieving skin irritation or inflammation contains Boerhavia diffusa extract, Glechoma hederacera extract or Citrus Grandis extract as an active ingredient. The weight ratio of the extract of Glechoma hederacera, Citrus Grandis and Boerhavia diffusa is 1-20:1-20:1-10. The Glechoma hederacera extract is obtained from root or leave of Glechoma hederacera. The Boerhavia diffusa extract is obtained from root and leaves of Boerhavia diffusa extract. The Citrus Grandis extract is obtained from Citrus Grandis fruit.
Abstract translation: 目的：提供用于缓解皮肤刺激或炎症的含有Glechoma hederacera提取物或Boerhavia diffusa提取物的组合物用于化妆品或制药领域。 构成：用于缓解皮肤刺激或炎症的组合物含有Boerhavia diffusa提取物，Glechoma hederacera提取物或Citrus Grandis提取物作为活性成分。 Glechoma hederacera，Citrus Grandis和Boerhavia diffusa的提取物的重量比为1-20：1-20：1-10。 Glechoma hederacera提取物从Glechoma hederacera的根或离开获得。 Boerhavia diffusa提取物从Boerhavia diffusa提取物的根和叶获得。 Citrus Grandis提取物是从Citrus Grandis水果中获得的。
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公开(公告)号：KR102212634B1
公开(公告)日：2021-02-08
申请号：KR1020140143348
申请日：2014-10-22
Applicant: (주)아모레퍼시픽
Abstract: 본발명은파라벤을포함하지않는구강용조성물에관한것으로서, 보다구체적으로는소듐벤조에이트와세틸피리디늄클로라이드, 스테아트리모늄클로라이드및 세틸트리메틸암모늄클로라이드중에서선택된 1종이상의화합물을함께사용함으로써파라벤을함유하지않으면서도우수한방부력을나타내는구강용조성물에관한것이다.
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公开(公告)号：KR1020160117073A
公开(公告)日：2016-10-10
申请号：KR1020150045693
申请日：2015-03-31
Applicant: (주)아모레퍼시픽
Abstract: 본발명은메틸클로로이소치아졸리논ㆍ메틸이소치아졸리논혼합액을포함하지않는모발용조성물에관한것으로서, 보다구체적으로는소듐벤조에이트, 세트리모늄클로라이드및 스테아트리모늄클로라이드를함께사용함으로써메틸클로로이소치아졸리논ㆍ메틸이소치아졸리논혼합액을함유하지않으면서도우수한방부력을나타내는모발용조성물에관한것이다.
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公开(公告)号：KR101617407B1
公开(公告)日：2016-05-02
申请号：KR1020100001645
申请日：2010-01-08
Applicant: (주)아모레퍼시픽
Abstract: 본발명은보다간편하고신속하며효율적으로물질의피부감작성을평가할수 있는물질의피부감작성평가방법을개시한다. 상기방법은펩타이드와평가대상물질을반응시켜반응물을얻는단계, 상기단계에서얻은반응물에시약을처리하고흡광도및 형광도중 하나이상을측정하는단계, 상기단계에서측정한흡광도및 형광도중 하나이상으로평가되는상기평가대상물질과펩타이드의반응정도에따라평가대상물질의피부감작성양성여부를평가하는단계를포함한다. 또한본 발명은물질의피부감작성평가장치를개시한다.
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Patent Agency Ranking
公开(公告)号：KR1020110042837A
公开(公告)日：2011-04-27
申请号：KR1020090099686
申请日：2009-10-20
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/345 , A61K2800/30 , A61K2800/72 , A61Q19/00
Abstract: PURPOSE: An external use skin composition containing 1,8-octandiol is provided to ensure excellent usage, safety, and preservation and to be applied to cosmetic field. CONSTITUTION: An external use skin composition of low irritation contains 1,8-octandiol without separate preservative ingredients. A cosmetic composition contains the external use skin composition. The cosmetic composition is manufactured in the form of lotion, astringent, eye cream, nutrition cream, massage cream, cleansing cream, cleansing foam, cleansing water, powder, essence, or pack.
Abstract translation: 目的：提供含有1,8-辛二醇的外用皮肤组合物，以确保优异的使用，安全性和保存性，并适用于化妆品领域。 构成：低刺激的外用皮肤组合物含有1,8-辛二醇，没有单独的防腐成分。 化妆品组合物含有外用皮肤组合物。 化妆品组合物以洗剂，收敛剂，眼霜，营养霜，按摩膏，清洁霜，清洁泡沫，清洁水，粉末，精华或包装的形式制成。
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公开(公告)号：KR1020100058866A
公开(公告)日：2010-06-04
申请号：KR1020080117431
申请日：2008-11-25
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition for anti-dandruff is provided to maintain pH concentration from 4.0 to 6.0 and to ensure safety to scalp. CONSTITUTION: A hair cosmetic composition for anti-dandruff contains 0.01-2.0 weight% of Zn-pyrithione of chemical formula 1 and 0.01-5.0 weight% of trihydroxystearin of chemical formula 2 as active ingredient. The acidity of the composition is maintained in pH 4.0-6.0. The pH adjusting agent is stearic acid citric acid, acetic acid, lactic acid, aspartic acid, or stearic acid. The hair cosmetic composition is used in the form of shampoo, rinse, hair tonic, or hair treatment.
Abstract translation: 目的：提供抗头皮屑的化妆品组合物，以将pH浓度从4.0保持至6.0，并确保头皮的安全性。 构成：用于防头皮屑的头发化妆品组合物含有0.01-2.0重量％的化学式1的锌 - 吡啶硫酮和0.01-5.0重量％的化学式2的三羟基硬脂酸酯作为活性成分。 组合物的酸度保持在pH 4.0-6.0。 pH调节剂是硬脂酸柠檬酸，乙酸，乳酸，天冬氨酸或硬脂酸。 头发化妆品组合物以洗发剂，漂洗剂，滋补剂或头发处理的形式使用。
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公开(公告)号：KR1020100046668A
公开(公告)日：2010-05-07
申请号：KR1020080105619
申请日：2008-10-28
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: An evaluation method is provided to objectively measure the relief effect of sensory skin irritation by quantifying the relief effect of sensory skin irritation about various anti-irritants through the change of concrete threshold. CONSTITUTION: A sensory skin irritation relief effect evaluation method comprises a step of measuring the change of a threshold before and after spreading an anti-irritant to a stimulus applied to the skin sensory nerve. The evaluation method quantitatively measures the change of the threshold by using a device. The evaluation method measures the change of the threshold value about a stimulus applied to at least one skin sensory nerve which is selected in a group which includes Aα, Aβ, Aδ, and C-fiber type. The evaluation method measures the change of the threshold value about a stimulus which is applied to the skin sensory nerve of Aδ or C-fiber type.
Abstract translation: 目的：通过改变混凝土阈值，量化消除各种抗刺激剂对皮肤刺激的缓解作用，提供评估方法，客观地测量感觉皮肤刺激的缓解作用。 构成：感官皮肤刺激缓解效果评估方法包括测量在将抗刺激剂涂抹于皮肤感觉神经的刺激之前和之后的阈值变化的步骤。 评价方法通过使用装置定量地测量阈值的变化。 评估方法测量关于施加到包括Aα，Aβ，Aδ和C纤维类型的组中选择的至少一种皮肤感觉神经的刺激的阈值变化。 评估方法测量施加于Aδ或C纤维类型的皮肤感觉神经的刺激的阈值变化。
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公开(公告)号：KR1020090020834A
公开(公告)日：2009-02-27
申请号：KR1020070085431
申请日：2007-08-24
Applicant: (주)아모레퍼시픽
Abstract: An in vitro skin sensitization test method is provided to rapidly analyze the skin sensitization-inducing possibility of material through the cell derived from the human body without use of animal, and classify and grade the skin sensitization-inducing possibility, thereby easily finding out the procedure required for the following process. The in vitro skin sensitization test method comprises the steps of: determining the treatment concentration of the estimation target material for the skin sensitization-inducing test; contacting the determined concentration of the estimation target material with the human origin cell, and culturing the cell; detecting CD86, CD54 and CD83 as costimulatory molecule, expressed from the cultured human origin cell; indexing the detected costimulatory molecules; grading and classifying the indexed detection amount; and determining the estimation target material as the skin sensitization-inducing material when the classified detection amount is the risk grade.
Abstract translation: 提供体外皮肤致敏试验方法，以快速分析通过源自人体的细胞的材料的皮肤敏化诱导可能性，而不使用动物，并分类和分级皮肤致敏诱导的可能性，从而容易地找出程序 需要以下过程。 体外皮肤致敏试验方法包括以下步骤：确定用于皮肤致敏诱导试验的估计目标材料的处理浓度; 将所测定的所述目标物质浓度与所述人源细胞接触，培养所述细胞; 从培养的人源细胞中检测CD86，CD54和CD83作为共刺激分子; 索引检测到的共刺激分子; 索引检测量分级和分类; 以及当所述分类检测量为风险等级时，将所述估计目标材料确定为所述皮肤致敏诱导材料。
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公开(公告)号：KR100862274B1
公开(公告)日：2008-10-09
申请号：KR1020070039895
申请日：2007-04-24
Applicant: (주)아모레퍼시픽
Abstract: A method for evaluating human skin damage by detecting furrows of human skin is provided to evaluate damage to human skin caused by a body washer by visualizing and quantifying the furrows. A method for evaluating human skin damage by detecting furrows of human skin includes the steps of: taking an image of the furrows by the skin damage by photographing human skin using an in vivo laser confocal microscopy; setting analysis section of the image of the furrows; visualizing the furrows of the human skin by using an image analysis program; and quantifying the number of pixels by measuring an area of the furrows in the analysis section.
Abstract translation: 提供了一种通过检测人体皮肤的沟槽来评价人体皮肤损伤的方法，以通过可视化和量化沟槽来评估由人体垫圈引起的对人体皮肤的损伤。 通过检测人皮肤的沟槽来评估人体皮肤损伤的方法包括以下步骤：通过使用体内激光共焦显微镜拍摄人体皮肤，通过皮肤损伤拍摄犁沟的图像; 犁沟图像的设定分析部分; 通过使用图像分析程序可视化人体皮肤的沟槽; 以及通过测量分析部分中的沟槽的面积来量化像素的数量。
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