公开(公告)号：KR1020110099369A

公开(公告)日：2011-09-08

申请号：KR1020100018344

申请日：2010-03-02

Applicant: 연세대학교 산학협력단 ,  대한민국(농촌진흥청장)

Inventor： 황재관 ,  김바름 ,  박광균 ,  이상국 ,  정원윤 ,  이승은 ,  성정숙 ,  성낙술 ,  박춘근 ,  이정훈 ,  이은숙

IPC: A61K36/532 ,  A61P3/10 ,  A61P3/00

CPC classification number: A61K36/532 ,  A23V2200/328 ,  A61K2236/331 ,  A61K2236/333 ,  Y10S514/866

Abstract: 본 발명은 당뇨 질환의 예방, 치료용 배초향(방아, 곽향;
Agastache

rugosa ) 추출물 및 이를 포함하는 치료용 제제에 관한 것으로, 더욱 상세하게는 퍼록시좀 증식인자 활성자 수용체 감마 (PPARγ)의 활성화와 지방세포의 분화 조절, 인슐린 민감도의 증가를 일으키는 배초향 추출물에 관한 것이다.

公开(公告)号：KR1020090084309A

公开(公告)日：2009-08-05

申请号：KR1020080010396

申请日：2008-01-31

Applicant: 이화여자대학교 산학협력단 ,  대한민국(농촌진흥청장)

Inventor： 이상국 ,  박헌주 ,  이학선 ,  성낙술 ,  이승은 ,  성정숙 ,  장인복

IPC: A23L1/29 ,  A23L1/221 ,  A23L2/38 ,  A23L1/30

CPC classification number: A23L33/00 ,  A23L2/38 ,  A23L27/10 ,  A23L33/10 ,  A23V2002/00 ,  A23V2200/318 ,  A23V2250/21

Abstract: A food additive comprising Physalis alkekengi extract is provided to show excellent tyrosinase inhibiting activity during in vitro experiment as well as melanin synthesis-inhibiting activity using an animal cell line of Melan-A. A food additive comprises 0.1-50wt% of Physalis alkekengi extract showing a whitening effect. The Physalis alkekengi extract can be used for at least one food selected among dried fruit products, fruit juices, vegetable juices, noodles, agricultural processed foods, marine processed foods, dairy products, fermented milk foods, grain products, microorganism fermented foods, seasonings, meat processed products and the like. A method for preparing Physalis alkekengi extract comprises the following steps of: mixing Physalis alkekengi and a solvent; performing hot-water extraction, reflux extraction, immersion extraction or pressure extraction at 10-100‹C for 1-4 days; and centrifuging, vacuum-filtering, concentrating and freeze-drying the extract. The solvent is one or more materials selected from the group consisting of water, ethanol, methanol, propanol, butanol, acetone, ethylacetate, hexane, butylene glycol, propylene glycol, hydrated butylene glycol, hydrated propylene glycol and hydrated glycerin.

Abstract translation: 提供了包含嗜碱性脂肪提取物的食品添加剂，以在体外实验中显示优异的酪氨酸酶抑制活性以及使用Melan-A的动物细胞系的黑色素合成抑制活性。 食品添加剂含有0.1-50％（重量）的苦参提取物，显示出美白效果。 苦瓜提取物可用于干果，果汁，蔬菜汁，面条，农业加工食品，海洋加工食品，乳制品，发酵乳食品，谷物制品，微生物发酵食品，调味料等中至少一种食品。 肉加工产品等。 一种制备苦碱提取物的方法，包括以下步骤：将苦参和溶剂混合; 进行热水提取，回流提取，浸提或10-100℃压力提取1-4天; 离心，真空过滤，浓缩和冷冻干燥提取物。 溶剂是一种或多种选自水，乙醇，甲醇，丙醇，丁醇，丙酮，乙酸乙酯，己烷，丁二醇，丙二醇，水合丁二醇，水合丙二醇和水合甘油的材料。