Abstract:
본명세서는중머리풀()을유효성분으로서포함하는조성물에관한것이다. 이러한본 명세서의조성물은산화적스트레스로부터신경세포를보호하고, 신경세포의사멸을억제하는효과를나타낸다. 또한, 세포내에서산화적스트레스의증가로인해발생하는세포사멸을억제하는항산화효소의발현을증가시킬수 있다. 따라서, 본명세서의조성물은산화적스트레스로부터신경세포의사멸로인하여발생될수 있는 2차적질병을예방, 개선또는치료하는효과를나타낼수 있어약학또는식품조성물로서사용될수 있다.
Abstract:
PURPOSE: A composition containingi oleanonic acid for preventing or treating dementia is provided to suppress beta-amyloid generation. CONSTITUTION: A composition for preventing or treating neurodegenerative diseases contains oleanonic acid of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient. A composition for preventing or treating neurodegenerative diseases contains Patrinia scabiosaefolia extract, dried material of the extract, or concentrate of the extract as an active ingredient. The Patrinia scabiosaefolia extract is isolated using water or alcohol of C1-C4.