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公开(公告)号：US10005814B2
公开(公告)日：2018-06-26
申请号：US15591490
申请日：2017-05-10
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Jerald K. Rasmussen , Kannan Seshadri , Robert T. Fitzsimons, Jr. , James I. Hembre , Catherine A. Bothof , Erin A. Satterwhite , George W. Griesgraber , Yi He , Louis C. Haddad
IPC: C08G73/00 , C07K1/14 , C12N11/08 , C08G73/02 , C08F126/02 , C08F120/60 , B01D21/01
CPC classification number: C07K1/14 , B01D21/01 , C08F120/60 , C08F126/02 , C08G69/10 , C08G73/0206 , C08G73/022 , C08G73/028 , C08L77/04 , C08L79/02 , C08L83/08 , C12N7/02 , C12N11/08 , G01N33/54393 , G01N33/545 , Y10T428/249978 , Y10T428/249991 , Y10T428/2935 , Y10T428/2998 , Y10T442/20
Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
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公开(公告)号：US09981244B2
公开(公告)日：2018-05-29
申请号：US15228469
申请日：2016-08-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Jerald K. Rasmussen , Catherine A. Bothof
IPC: B01J20/26 , C09D5/00 , B01J20/289 , B01J20/32 , C08J7/18 , G01N33/543 , C08J7/04 , C09D179/02 , C08G73/02 , C07K1/22 , C07K14/765 , C07K16/00 , C09D4/00 , C09D133/24
CPC classification number: B01J20/267 , B01J20/289 , B01J20/3212 , B01J20/3219 , B01J20/327 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , C07K1/22 , C07K14/765 , C07K16/00 , C08G73/02 , C08J7/047 , C08J7/18 , C08J2333/24 , C08J2377/06 , C08J2433/14 , C08J2433/24 , C09D4/00 , C09D5/002 , C09D133/24 , C09D179/02 , G01N33/54393
Abstract: Ligand-functionalized substrates are describe that are useful in selectively binding and removing biological materials from biological samples, and methods for preparing the same.
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公开(公告)号：US09958364B2
公开(公告)日：2018-05-01
申请号：US15023729
申请日：2014-09-25
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Jerald K. Rasmussen , Catherine A. Bothof , George W. Griesgraber , Semra Colak Atan , James I. Hembre , Robert T. Fitzsimons, Jr.
IPC: B01D71/44 , G01N1/40 , C07K1/34 , C08J7/18 , C07F9/38 , G01N33/544 , C07K1/18 , B01D67/00 , B01D71/52 , B01D71/56 , B01J20/26 , B01J20/28 , B01J20/32
CPC classification number: G01N1/405 , B01D67/0093 , B01D71/44 , B01D71/52 , B01D71/56 , B01D2323/345 , B01D2323/38 , B01D2325/14 , B01D2325/16 , B01J20/261 , B01J20/28038 , B01J20/321 , B01J20/3242 , B01J20/3251 , B01J20/3253 , B01J20/327 , C07F9/3808 , C07K1/18 , C07K1/34 , C08J7/18 , C08J2377/00 , G01N1/4077 , G01N33/544 , G01N2001/4088 , G01N2333/924
Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
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公开(公告)号：US09758547B2
公开(公告)日：2017-09-12
申请号：US13848257
申请日：2013-03-21
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Jerald K. Rasmussen , Kannan Seshadri , Robert T. Fitzsimons, Jr. , James I. Hembre , Catherine A. Bothof , Erin A. Satterwhite , George W. Griesgraber , Yi He , Louis C. Haddad
IPC: C07K1/14 , C08G69/10 , C08G73/02 , C08L77/04 , C08L79/02 , C08L83/08 , G01N33/543 , G01N33/545 , C12N7/02 , C12N11/08
CPC classification number: C07K1/14 , B01D21/01 , C08F120/60 , C08F126/02 , C08G69/10 , C08G73/0206 , C08G73/022 , C08G73/028 , C08L77/04 , C08L79/02 , C08L83/08 , C12N7/02 , C12N11/08 , G01N33/54393 , G01N33/545 , Y10T428/249978 , Y10T428/249991 , Y10T428/2935 , Y10T428/2998 , Y10T442/20
Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
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公开(公告)号：US20160231208A1
公开(公告)日：2016-08-11
申请号：US15023729
申请日：2014-09-25
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Jerald K. Rasmussen , Catherine A. Bothof , George W. Griesgraber , Semra Colak Atan , James I. Hembre , Robert T. Fitzsimons, JR.
CPC classification number: G01N1/405 , B01D67/0093 , B01D71/44 , B01D71/52 , B01D71/56 , B01D2323/345 , B01D2323/38 , B01D2325/14 , B01D2325/16 , B01J20/261 , B01J20/28038 , B01J20/321 , B01J20/3242 , B01J20/3251 , B01J20/3253 , B01J20/327 , C07F9/3808 , C07K1/18 , C07K1/34 , C08J7/18 , C08J2377/00 , G01N1/4077 , G01N33/544 , G01N2001/4088 , G01N2333/924
Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
Abstract translation: 可用于生物材料捕获的制品包括（a）多孔基材; 至少一种单价烯属不饱和基团，（2）至少一种选自酸性基团的单价配基官能团，碱性基团 除胍基以外的盐及其盐，和（3）与至少一个烯键式不饱和基团和至少一个配体官能团通过至少6个连接原子的链连接的单价基团的多价间隔基团 。
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Patent Agency Ranking
公开(公告)号：US09290580B2
公开(公告)日：2016-03-22
申请号：US14672871
申请日：2015-03-30
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Simon K. Shannon , Catherine A. Bothof , Babu N. Gaddam , Jerald K. Rasmussen , Richard B. Ross
IPC: B01J20/32 , B01J39/18 , B01J41/12 , B01J20/26 , C08F20/56 , C08F220/56 , C07K17/08 , B01D15/08 , B01J20/286 , B01J39/16 , B01J20/287 , C07K1/22 , C08F271/02 , B01J39/20 , B01J41/14 , B01D15/38
CPC classification number: C07K17/08 , B01D15/08 , B01D15/3804 , B01D15/3809 , B01J20/264 , B01J20/286 , B01J20/287 , B01J20/3204 , B01J20/3208 , B01J20/3219 , B01J20/3242 , B01J20/3255 , B01J20/3276 , B01J20/3278 , B01J20/328 , B01J39/17 , B01J39/18 , B01J39/20 , B01J41/12 , B01J41/14 , B01J2220/52 , B01J2220/54 , B01J2220/58 , B01J2220/62 , C07K1/22 , C08F271/02
Abstract: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.
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公开(公告)号：US09259689B2
公开(公告)日：2016-02-16
申请号：US13674990
申请日：2012-11-13
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Clinton P. Waller, Jr. , Douglas E. Weiss , Catherine A. Bothof , Kannan Seshadri
IPC: C08J7/18 , B01D67/00 , D06M14/26 , B01D69/10 , B01D39/16 , B01D63/00 , B01D63/10 , B01D63/14 , D04H1/42 , D04H1/56 , D06M14/28
CPC classification number: B01D67/0093 , B01D39/1623 , B01D39/1692 , B01D63/00 , B01D63/10 , B01D63/14 , B01D67/009 , B01D69/10 , B01D69/105 , B01D2239/0421 , B01D2239/0464 , B01D2239/065 , B01D2239/069 , B01D2239/10 , B01D2239/1216 , B01D2239/1225 , B01D2239/1266 , B01D2239/1291 , B01D2323/385 , D04H1/42 , D04H1/4334 , D04H1/4382 , D04H1/56 , D06M14/26 , D06M14/28 , Y10T442/2008
Abstract: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising anionic monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as monoclonal antibodies (MAb), from a fluid mixture.
Abstract translation: 公开了接枝非织造基材，其平均纤维尺寸为0.7至15微米，空隙体积为50至95％，以及包含接枝到非织造基材表面的阴离子单体单元的聚合物。 该制品可以用作过滤元件以从流体混合物中纯化或分离靶物质，例如单克隆抗体（MAb）。
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公开(公告)号：US20140364519A1
公开(公告)日：2014-12-11
申请号：US14467651
申请日：2014-08-25
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Catherine A. Bothof , Yi He , Jerald K. Rasmussen , Kannan Seshadri , Clinton P. Waller, JR. , Douglas E. Weiss
IPC: C08G69/48 , C07C277/08 , C08F259/08 , B01D39/16 , C07C279/12 , C07C279/14
CPC classification number: C07C279/12 , B01D39/1676 , B01J20/285 , C07C277/08 , C07C279/14 , C07C281/16 , C07K1/34 , C08F259/08 , C08F283/04 , C08G69/48 , C08J7/18 , C08J9/283 , C08J9/42 , C08J2327/16 , C08J2377/00 , C12N7/00 , Y02C10/08 , Y10T428/31855
Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
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公开(公告)号：US20140046029A1
公开(公告)日：2014-02-13
申请号：US14058561
申请日：2013-10-21
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Simon K. Shannon , Catherine A. Bothof , Babu N. Gaddam , Jerald K. Rasmussen , Richard B. Ross
IPC: C08F271/02 , C07K1/22
CPC classification number: C07K17/08 , B01D15/08 , B01D15/3804 , B01D15/3809 , B01J20/264 , B01J20/286 , B01J20/287 , B01J20/3204 , B01J20/3208 , B01J20/3219 , B01J20/3242 , B01J20/3255 , B01J20/3276 , B01J20/3278 , B01J20/328 , B01J39/17 , B01J39/18 , B01J39/20 , B01J41/12 , B01J41/14 , B01J2220/52 , B01J2220/54 , B01J2220/58 , B01J2220/62 , C07K1/22 , C08F271/02
Abstract: Articles that contain a solid support with a grafted chain extending from the solid support, methods of making these articles, and various uses of the articles are described. More specifically, the grafted chain has a functional group that can react with or interact with target compound. Alternatively, the functional group on the grafted chain can react with a modifying agent to provide another group that can react with or interact with the target compound. The grafted chains are attached to the solid support through a ring-opened azlactone group. The articles can be used to purify the target compound or to separate the target compound from other molecules in a sample.
Abstract translation: 描述了含有从固体支持物延伸的接枝链的固体支持物的制品，制造这些制品的方法以及制品的各种用途。 更具体地，接枝链具有可与目标化合物反应或与其相互作用的官能团。 或者，接枝链上的官能团可以与改性剂反应，以提供可与目标化合物反应或与目标化合物相互作用的另一个基团。 接枝的链通过开环的吖内酯基团连接到固体支持物上。 该制品可用于纯化目标化合物或将目标化合物与样品中的其它分子分离。
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公开(公告)号：US08459470B2
公开(公告)日：2013-06-11
申请号：US13708653
申请日：2012-12-07
Applicant: 3M Innovative Properties Company
Inventor： Douglas E. Weiss , Clinton P. Waller, Jr. , Michael R. Berrigan , Andrew W. Rabins , Jeffrey A. Lucas , Kannan Seshadri , Catherine A. Bothof
CPC classification number: B01D39/163 , C08F255/00 , C08F289/00 , C08F291/00 , C08L51/08 , C08L2666/02
Abstract: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising cationic aminoalkyl(meth)acryloyl monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as oligonucleotides or monoclonal antibodies (MAb), from a fluid mixture.
Abstract translation: 公开了接枝非织造基材，其平均纤维尺寸为0.7-15微米，空隙体积为50至95％，以及包含接枝到非织造基材表面的阳离子氨基烷基（甲基）丙烯酰基单体单元的聚合物。 该制品可以用作过滤元件以从流体混合物纯化或分离靶物质，例如寡核苷酸或单克隆抗体（MAb）。
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