公开(公告)号：US20120182964A1

公开(公告)日：2012-07-19

申请号：US13497150

申请日：2010-11-02

Applicant: Xiqi Gao ,  Bin Jiang ,  Xiaohu You ,  Teer Ba ,  Shi Jin ,  Jue Wang ,  Dongming Wang ,  Yanxiang Jiang

Inventor： Xiqi Gao ,  Bin Jiang ,  Xiaohu You ,  Teer Ba ,  Shi Jin ,  Jue Wang ,  Dongming Wang ,  Yanxiang Jiang

IPC: H04W72/04

CPC classification number: H04B7/0697 ,  H04J11/0033 ,  H04L25/0228

Abstract: A pilot and channel estimation method for SDMA MIMO transmission downlink is provided in the present invention, and the method provides possibility for saving the orthogonal pilot resources; the pilot signals of different users in the transmitting antenna domain can occupy the same time-frequency resources, and thereby the pilot overhead of system resources can be reduced greatly; the method includes: for the MIMO transmission downlink that employs pre-coding for SDMA, taking the quantity of orthogonal pilot resources occupied by the users in the pre-coding domain as the number of data streams that can be transmitted or the number of spatial dimensions occupied first, at the transmitting end of the base station; then, performing SDMA transmission pre-coding for the orthogonal pilots in the pre-coding domain in the same way as the data signals, to obtain the pilot signals of the users in the transmitting antenna domain; wherein, the pilots of the users in the pre-coding domain can be orthogonal in the frequency domain or code domain, and the pilots of different users in the pre-coding domain can be identical or not identical to each other; the pilot signals of different users in the transmitting antenna domain can occupy the same time-frequency resources.

Abstract translation: 本发明提供了一种用于SDMA MIMO传输下行链路的导频和信道估计方法，该方法提供了保存正交试验资源的可能性; 发射天线域中不同用户的导频信号可以占用相同的时频资源，从而大大降低系统资源的导频开销; 该方法包括：对于采用SDMA预编码的MIMO传输下行链路，将预编码域中的用户占用的正交导频资源的数量作为可以发送的数据流的数量或空间维数 首先占用基站的发射端; 然后以与数据信号相同的方式对预编码域中的正交导频执行SDMA传输预编码，以获得发射天线域中用户的导频信号; 其中，预编码域中的用户的导频可以在频域或码域中正交，并且预编码域中的不同用户的导频可以相同或不相同; 发射天线域中不同用户的导频信号可以占用相同的时频资源。

公开(公告)号：US20110002952A1

公开(公告)日：2011-01-06

申请号：US12866270

申请日：2009-02-05

Applicant: Jingwu Duan ,  David S. Weinstein ,  Bin Jiang

Inventor： Jingwu Duan ,  David S. Weinstein ,  Bin Jiang

IPC: A61K31/5377 ,  C07D491/147 ,  A61K31/4375 ,  A61K38/26 ,  A61K38/28 ,  A61K39/00 ,  A61P37/00 ,  A61P29/00 ,  A61P3/00 ,  A61P37/06 ,  A61P19/02 ,  A61P25/00 ,  A61P11/06 ,  A61P1/00 ,  A61P17/06

CPC classification number: C07D491/147

Abstract: Novel non-steroidal compounds are provided which are useful in treating diseases or disorders associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity, including metabolic and inflammatory and immune diseases or disorders, having the structure of formula (I): an enantiomer, diastereomer, or tautomer thereof, or a prodrug ester thereof, or a pharmaceutically-acceptable salt thereof, in which: Z is heterocyclo or heteroaryl; -A is a 5- to 8-membered carbocyclic ring or a 5- to 8-membered heterocyclic ring; B1 and B2 rings are pyridyl rings, wherein the B1 and B2 rings are each fused to the A ring and the B1 ring is optionally substituted by one to three groups which are the same or different and are independently selected from R1, R2, and R4, and the B2 ring is optionally substituted by one to three groups which are the same or different and are independently selected from R3, R7, and R3 71, J2, and J3 are at each occurrence the same or different and are independently -AIQA2-; Q is a bond, O, S, S(0), or S(O)2; A1 and A2 are the same or different and are at each occurrence independently selected from a bond, C1-3 alkylene, substituted C1-3 alkylene, C24 alkenylene, and substituted C24 alkenylene, provided that A1 and A2 are chosen so that ring A is a 5- to 8-membered carbocyclic or heterocyclic ring; R1 to R11 are as defined herein.

Abstract translation: 提供新的非甾体化合物，其可用于治疗与调节糖皮质激素受体，AP-1和/或NF-κB活性相关的疾病或病症，包括具有结构的代谢和炎症和免疫疾病或病症 式（I）的化合物：其对映异构体，非对映异构体或其互变异构体或其前药酯或其药学上可接受的盐，其中：Z是杂环基或杂芳基; -A是5-至8-元碳环或5-至8-元杂环; B1和B2环是吡啶环，其中B1和B2环各自与A环稠合，B1环任选被一至三个相同或不同并且独立地选自R 1，R 2和R 4的基团取代 并且B2环任选地被一至三个相同或不同并且独立地选自R3，R7和R371的基团取代，J2和J3在每次出现时相同或不同，并且独立地为-AIQA2- ; Q是键，O，S，S（0）或S（O）2; A1和A2相同或不同，并且在每次出现时独立地选自键，C1-3亚烷基，取代的C1-3亚烷基，C24亚烯基和取代的C24亚烯基，条件是选择A1和A2，使得环A为 5-至8-元碳环或杂环; R1至R11如本文所定义。

公开(公告)号：USD607435S1

公开(公告)日：2010-01-05

申请号：US29334661

申请日：2009-03-31

Applicant: Bin Jiang

Designer： Bin Jiang

公开(公告)号：US20090190619A1

公开(公告)日：2009-07-30

申请号：US12363103

申请日：2009-01-30

Applicant: Haihua Qi ,  Bifeng Xiong ,  Bin Jiang ,  Hong Ma

Inventor： Haihua Qi ,  Bifeng Xiong ,  Bin Jiang ,  Hong Ma

IPC: H01S5/024

CPC classification number: H01S5/4025 ,  H01S5/02272 ,  H01S5/024 ,  H01S5/4018

Abstract: The present invention provides a semiconductor laser package including a heat sink, a laser bar with a plurality of lasers on the heat sink, an insulated layer arranged between said heat sink and said laser bar, a solder layer combining said insulated layer with said laser bar, and a clearance crossing said solder layer defined between adjacent lasers.

Abstract translation: 本发明提供了一种半导体激光器封装，其包括散热器，在散热器上具有多个激光器的激光棒，布置在所述散热器和所述激光棒之间的绝缘层，将所述绝缘层与所述激光棒 以及在相邻激光器之间限定的焊料层的间隙。

公开(公告)号：US07294624B2

公开(公告)日：2007-11-13

申请号：US10321144

申请日：2002-12-17

Applicant: Jingwu Duan ,  Bin Jiang ,  Lihua Chen ,  Zhonghui Lu ,  Joseph Barbosa ,  William J. Pitts

Inventor： Jingwu Duan ,  Bin Jiang ,  Lihua Chen ,  Zhonghui Lu ,  Joseph Barbosa ,  William J. Pitts

IPC: A01N43/58 ,  A61K31/50 ,  C07D237/00 ,  C07D239/02

CPC classification number: C07D239/54 ,  C07D239/62 ,  C07D239/70 ,  C07D401/12 ,  C07D403/12 ,  C07D417/12 ,  C07D471/10 ,  C07D487/10 ,  C07D491/10

Abstract: The present application describes novel barbituric acid derivatives of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, L, R1, R2, R3, R4, R5, n, W, U, X, Y, Z, Ua, Xa, Ya, and Za are defined in the present specification, which are useful as TNF-α converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitors.

Abstract translation: 本申请描述了式I的新型巴比妥酸衍生物或其药学上可接受的盐或前药形式，其中A，B，L，R 1，R 2， R 4，R 4，R 5，n，W，U，X，Y，Z，U a， 在本说明书中定义，其可用作TNF-α转化酶（TACE）和/或 基质金属蛋白酶（MMP）抑制剂。

公开(公告)号：US09221826B2

公开(公告)日：2015-12-29

申请号：US14005572

申请日：2012-03-16

Applicant: Stephen T. Wrobleski ,  Jagabandhu Das ,  Lidia M. Doweyko ,  Junqing Guo ,  John Hynes ,  Bin Jiang ,  James Kempson ,  Shuqun Lin ,  Steven H. Spergel ,  John S. Tokarski ,  Hong Wu ,  Bingwei Vera Yang

Inventor： Stephen T. Wrobleski ,  Jagabandhu Das ,  Lidia M. Doweyko ,  Junqing Guo ,  John Hynes ,  Bin Jiang ,  James Kempson ,  Shuqun Lin ,  Steven H. Spergel ,  John S. Tokarski ,  Hong Wu ,  Bingwei Vera Yang

IPC: A61K31/5025 ,  A61K31/675 ,  C07D487/04 ,  C07F9/6561

CPC classification number: C07D487/04 ,  C07F9/6561

Abstract: Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof. The compounds of formula (I) inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

Abstract translation: 公开了式（I）的化合物及其药学上可接受的盐。 式（I）化合物抑制JAK3的酪氨酸激酶活性，从而使其可用于治疗炎性和自身免疫性疾病。

公开(公告)号：US08987268B2

公开(公告)日：2015-03-24

申请号：US14005568

申请日：2012-03-16

Applicant: Stephen T. Wrobleski ,  Jagabandhu Das ,  Jingwu Duan ,  Junqing Guo ,  John Hynes ,  Bin Jiang ,  James Kempson ,  Shuqun Lin ,  Zhonghui Lu ,  William J. Pitts ,  Steven H. Spergel ,  Hong Wu ,  Bingwei Vera Yang

Inventor： Stephen T. Wrobleski ,  Jagabandhu Das ,  Jingwu Duan ,  Junqing Guo ,  John Hynes ,  Bin Jiang ,  James Kempson ,  Shuqun Lin ,  Zhonghui Lu ,  William J. Pitts ,  Steven H. Spergel ,  Hong Wu ,  Bingwei Vera Yang

IPC: C07D487/04 ,  C07D471/04 ,  A01N43/58 ,  A61K31/50

CPC classification number: C07D487/04 ,  C07D519/00

Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

Abstract translation: 本发明提供式I化合物及其药学上可接受的盐。 式I化合物抑制JAK3的酪氨酸激酶活性，从而使其可用于治疗炎症和自身免疫性疾病。

公开(公告)号：US08846673B2

公开(公告)日：2014-09-30

申请号：US13388700

申请日：2010-08-11

Applicant: Jingwu Duan ,  Bin Jiang ,  Zhonghui Lu

Inventor： Jingwu Duan ,  Bin Jiang ,  Zhonghui Lu

IPC: A61K31/535 ,  C07D471/04

CPC classification number: C07D471/04

Abstract: Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, (I) are useful as kinase modulators, including Btk modulation, wherein A1, A2, A3, R4 are as defined herein.

Abstract translation: 具有式（I）的化合物及其对映异构体和非对映异构体，药学上可接受的盐，（I）可用作激酶调节剂，包括Btk调节，其中A1，A2，A3，R4如本文所定义。

公开(公告)号：US20140011795A1

公开(公告)日：2014-01-09

申请号：US14005570

申请日：2012-03-16

Applicant: Stephen T. Wrobleski ,  Gregory D. Brown ,  Lidia M. Doweyko ,  Jingwu Duan ,  Junqing Guo ,  John Hynes ,  Bin Jiang ,  James Kempson ,  Shuqun Lin ,  Zhonghui Lu ,  Steven H. Spergel ,  John S. Tokarski ,  Hong Wu ,  Bingwei Vera Yang

Inventor： Stephen T. Wrobleski ,  Gregory D. Brown ,  Lidia M. Doweyko ,  Jingwu Duan ,  Junqing Guo ,  John Hynes ,  Bin Jiang ,  James Kempson ,  Shuqun Lin ,  Zhonghui Lu ,  Steven H. Spergel ,  John S. Tokarski ,  Hong Wu ,  Bingwei Vera Yang

IPC: C07D487/04 ,  C07D471/04

CPC classification number: C07D487/04 ,  C07D471/04 ,  C07D519/00

Abstract: Disclosed are compounds of Formula (I), and pharmaceutically acceptable salts thereof. The compounds of formula (I) inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

Abstract translation: 公开了式（I）的化合物及其药学上可接受的盐。 式（I）化合物抑制JAK3的酪氨酸激酶活性，从而使其可用于治疗炎性和自身免疫性疾病。

公开(公告)号：US20130137235A1

公开(公告)日：2013-05-30

申请号：US13512415

申请日：2011-04-22

Applicant: Qi Yu ,  Xiangzhan Wang ,  Ning Ning ,  Jingchun Li ,  Hongdong Yang ,  Xianwei Ying ,  Weijie Zhou ,  Bin Jiang ,  Yong Wang

Inventor： Qi Yu ,  Xiangzhan Wang ,  Ning Ning ,  Jingchun Li ,  Hongdong Yang ,  Xianwei Ying ,  Weijie Zhou ,  Bin Jiang ,  Yong Wang

IPC: H01L29/66

CPC classification number: H01L29/4983 ,  H01L21/823807 ,  H01L21/823828 ,  H01L21/823864 ,  H01L29/0649 ,  H01L29/0653 ,  H01L29/7842 ,  H01L29/7843 ,  H01L29/7845 ,  H01L29/7848 ,  H01L29/7849

Abstract: A MOS transistor (60, 62) is provided. The structure of the transistor (60, 62) includes: a semiconductor substrate (10), a channel area (20, 24), source/drain regions (22, 26), a gate (30, 32), a gate insulating layer (11), a shallow trench isolation region (12), a passive layer (50, 52), and holes (40, 42) formed with a certain distance to the gate insulating layer (11). Wherein both the shapes of the holes (40, 42) and the Young's modulus' difference between the material in the holes (40, 42) and that around the holes (40, 42) contribute to the stress concentration effect, thus the stress in the channel area (20, 24) is enhanced. The structure of the transistor (60, 62) can greatly reduce the stress attenuation during the transmission from stress resource to the sensitive region, and concentrate the stress in the sensitive region. The structure can be involved in large size device, especially.

Abstract translation: 提供了MOS晶体管（60,62）。 晶体管（60,62）的结构包括：半导体衬底（10），沟道区（20,24），源极/漏极区（22,26），栅极（30,32），栅极绝缘层 （11），浅沟槽隔离区（12），钝化层（50,52）和与栅绝缘层（11）形成一定距离的孔（40,42）。 其中孔（40,42）的形状和孔（40,42）中的材料与孔（40,42）周围的材料之间的杨氏模量差都有助于应力集中效应，因此应力 增加了通道区域（20,24）。 晶体管（60,62）的结构可以大大降低从应力资源向敏感区域传输过程中的应力衰减，并将应力集中在敏感区域。 该结构可以涉及大尺寸装置，特别是。