ELECTRON INDUCED DISSOCIATION DEVICES AND METHODS
    48.
    发明公开
    ELECTRON INDUCED DISSOCIATION DEVICES AND METHODS 审中-公开
    电子诱发离散装置和方法

    公开(公告)号:EP3241231A1

    公开(公告)日:2017-11-08

    申请号:EP15875330.1

    申请日:2015-12-21

    Inventor: BABA, Takashi

    CPC classification number: H01J49/0072 H01J49/0054 H01J49/062 H01J49/063

    Abstract: A method and apparatus for conducting reactions between precursor ions and reagent ions, for example, a reaction between a precursor cation and an electron, such as ECD, are disclosed. The apparatus comprises first, second, and third pathways, each of which extends at least partially along a central axis, and wherein the second central axis is orthogonal to the first and third central axes. Charged species can be introduced into the second pathway as the ions are transmitted therethrough, thereby increasing precursor ion and charged species interaction without simultaneous trapping of the species.

    MULTIPLEXED PRECURSOR ISOLATION FOR MASS SPECTROMETRY
    49.
    发明公开
    MULTIPLEXED PRECURSOR ISOLATION FOR MASS SPECTROMETRY 审中-公开
    用于质谱分析的多重前体分离

    公开(公告)号:EP3157043A1

    公开(公告)日:2017-04-19

    申请号:EP16201479.9

    申请日:2014-10-07

    Inventor: BABA, Takashi

    Abstract: Systems and methods for multiplexed precursor ion selection are provided. A mass isolator includes a selection region of rods, a transmission region of rods, and a barrier electrode lens separating the selection and transmission regions. Two or more different precursor ions are selected by applying two or more different AC voltage frequencies to rods of a selection region in order to resonate the two or more different precursor ions from a continuous beam of ions. The two or more different precursor ions are transmitted by applying a DC voltage to the barrier electrode lens, creating an electric field potential barrier over which only the resonating ions are transmitted. Precursor ions of product ions from combined product ion spectra produced by multiplexed precursor ion selection are identified by grouping the target precursor ions.

    Abstract translation: 提供了用于多路复用前体离子选择的系统和方法。 质量隔离器包括杆的选择区域,杆的传输区域以及分隔选择区域和透射区域的屏障电极透镜。 通过对选择区域的棒施加两个或更多个不同的AC电压频率来选择两个或更多个不同的前体离子,以便使来自连续离子束的两种或更多种不同的前体离子共振。 通过向阻挡电极透镜施加直流电压来传输两种或更多种不同的前体离子,从而形成只有谐振离子才透过的电场势垒。 通过对靶前体离子进行分组来鉴定来自通过多重前体离子选择产生的组合产物离子谱的产物离子的前体离子。

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