公开(公告)号：JPS6429379A

公开(公告)日：1989-01-31

申请号：JP18462187

申请日：1987-07-23

Applicant: KUMIAI CHEMICAL INDUSTRY CO

Inventor： KATO HIDEKI ,  KOBAYASHI MINESUKE ,  SHIMAZU HOTOKU ,  SUZUKI AKINORI ,  ISOGAI AKIRA ,  TADA OSAMU

IPC: C12P17/18 ,  A61K31/365 ,  A61P33/00 ,  A61P33/10 ,  C07D307/00 ,  C07D309/00 ,  C07D313/00 ,  C07D493/22 ,  C12R1/55

Abstract: NEW MATERIAL:Physiologically active substances KSB-1939H3 (n is 1) and KSB-1939H5 (n is 2) expressed by the formula (n is 1 or 2). USE:A natural physiologically active substance capable of exhibiting insecticidal, acaricidal and anthelmintic action. PREPARATION:A microorganism, belonging to the genus Streptomyces and capable of producing the compounds expressed by the formula, e.g. strain KSB-1939 (FERM-P No.1901), is cultivated to collect the aimed compounds expressed by the formula alone or as a mixture from the resultant culture.

公开(公告)号：JPS6429378A

公开(公告)日：1989-01-31

申请号：JP18462087

申请日：1987-07-23

Applicant: KUMIAI CHEMICAL INDUSTRY CO

Inventor： KATO HIDEKI ,  KOBAYASHI MINESUKE ,  SHIMAZU HOTOKU ,  SUZUKI AKINORI ,  ISOGAI AKIRA ,  TADA OSAMU

IPC: C12P17/18 ,  A61K31/365 ,  A61P33/00 ,  A61P33/10 ,  C07D307/00 ,  C07D309/00 ,  C07D313/00 ,  C07D493/22 ,  C12R1/55

Abstract: NEW MATERIAL:Physiologically active substances KSB-1939H2 (R is methyl) and KSB-1939H4 (R is ethyl) expressed by the formula (R is methyl or ethyl). USE:A natural physiologically active substance capable of exhibiting powerful insecticidal, acaricidal and anthelmintic effects. PREPARATION:A microorganism, belonging to the genus Streptomyces and capable of producing the compounds expressed by the formula, e.g. strain KSB-1939 (FERM-P No.1901), is cultivated to collect the compounds expressed by the formula alone or as a mixture from the resultant culture.

公开(公告)号：JPS6041677B2

公开(公告)日：1985-09-18

申请号：JP8023679

申请日：1979-06-27

Applicant: KUMIAI CHEMICAL INDUSTRY CO

Inventor： CHOMARU ISAO ,  SUGYAMA HIDETOSHI ,  NITSUTA YASUYATA ,  FUJIMORI KUNIHIKO ,  HIRANO TADAMI ,  TADA OSAMU

IPC: A01N57/16 ,  C07F9/09 ,  C07F9/165 ,  C07F9/655

公开(公告)号：JPS58124795A

公开(公告)日：1983-07-25

申请号：JP558582

申请日：1982-01-18

Applicant: KUMIAI CHEMICAL INDUSTRY CO

Inventor： NISHIMURA TATSUMI ,  HORII TETSUO ,  HIRANO TADAMI ,  TADA OSAMU

IPC: A01N57/12 ,  C07F9/17

Abstract: NEW MATERIAL:A compound of formulaI[R and R are lower alkyl; R is 5-12C alkyl or formula II (X is halogen)]. USE:An insecticide, acaricide, nematocide and germicide. PROCESS:A compound of formula III, e.g. O-methyl-S-sec-butylchloride phosphorothiolate of formula IV, is reacted with a compound of formula V, e.g. 2,2,2- trichloro-1-iso-pentylthioethanol, in the presence of an acid acceptor, e.g. triethylamine.

公开(公告)号：JPS5841891A

公开(公告)日：1983-03-11

申请号：JP14136881

申请日：1981-09-08

Applicant: KUMIAI CHEMICAL INDUSTRY CO

Inventor： NISHIMURA TATSUMI ,  HORII TETSUO ,  HIRANO TADAMI ,  TADA OSAMU

IPC: C07F9/165 ,  A01N57/10

Abstract: NEW MATERIAL:A compound of formulaI[R , R are lower alkyl; R is lower alkyl, cyclohexyl, furfuryl, formula II (X is halogen, lower alkyl; n is 0-2), alkoxycarbonylmethyl]. EXAMPLE:O-Ethyl-S-n-propyl-O-( 2, 2, 2-trichloro-1-phenylthioethyl )-phosphorothioate of formula III. USE:Insecticide, acaricide, fungicide: it is free from environmental pollution. PREPARATION:For example, 2,2,2-trichloro-1-phenylthioethanol and triethylamine are dissolved in benzene and O-ethyl-S-n-propyl chloride phosphorothiolate is added thereto dropwise to effect the reaction to give the exemplified compound.

公开(公告)号：JPS54141752A

公开(公告)日：1979-11-05

申请号：JP4707578

申请日：1978-04-20

Applicant: KUMIAI CHEMICAL INDUSTRY CO

Inventor： CHIYOMARU ISAO ,  FUJIMORI KUNIHIKO ,  HORII TETSUO ,  HIRANO TADAMI ,  TADA OSAMU ,  KOYASU HIDEO

IPC: A01N57/14 ,  C07F9/165

Abstract: NEW MATERIAL:A compound of formula I (R is 1-4C alkyl; X is H, Cl). EXAMPLE:O-ethyl S-n-propyl S-(N-4-chlorobenzyl-N-sec-butylcarbamolymethyl) phosphorodithioate. USE:Insecticide having excellent effect especially to rice stem borer, green rice leafhopper, etc., compared with O-ethyl S-n-propyl S-(n-benzylcarbamoyl-methyl)phosphorodithioate. PROCESS:The compound I is prepared by reacting 1 mole of the compound III with 1.2 moles of the compound II (M is alkali metal, quaternary ammonium) at room temp.-100 deg.C, (pref. 30-80 deg.C) for 2-3 hours.