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    Method and system for setting up a bearer
    41.
    发明授权
    Method and system for setting up a bearer 有权
    建立承载的方法和系统

    公开(公告)号：US08243675B2

    公开(公告)日：2012-08-14

    申请号：US12757638

    申请日：2010-04-09

    Applicant: Jinyi Zhou ,  Lan Liu ,  Xiaolong Guo ,  Ming Li ,  Zhe Chen ,  Qi Yu

    Inventor： Jinyi Zhou ,  Lan Liu ,  Xiaolong Guo ,  Ming Li ,  Zhe Chen ,  Qi Yu

    IPC: H04W4/00

    CPC classification number: H04L12/66 ,  H04W28/0268 ,  H04W72/087 ,  H04W76/10 ,  H04W76/11 ,  H04W76/12

    Abstract: Method and system for setting up a bearer are disclosed. The bearer setup method includes these steps: a packet data network gateway (PGW) obtains first quality of service (QoS) information and a first bearer identifier (ID), and sets up a bearer between the PGW and a radio access network (RAN) according to the first QoS information, where the bearer is associated with the first bearer ID; the RAN sets up a radio bearer (RB) with a user equipment (UE) according to second QoS information associated with the first QoS information, where the RB is associated with a second bearer ID associated with the first bearer ID. According to the technical solution of the present invention, when the UE is connected to a serving gateway (SGW) through a serving general packet radio service support node (SGSN), the SGSN and the SGW set up a bearer between the UE and the PGW. Thus, resources of each network entity in a network are fully utilized.

    Abstract translation: 公开了建立承载的方法和系统。 承载建立方法包括以下步骤：分组数据网络网关（PGW）获得第一服务质量（QoS）信息和第一承载标识符（ID），并且在PGW和无线接入网络（RAN）之间建立承载， 根据第一QoS信息，其中承载与第一承载ID相关联; RAN根据与第一QoS信息相关联的第二QoS信息与用户设备（UE）建立无线承载（RB），其中RB与与第一承载ID相关联的第二承载ID相关联。 根据本发明的技术方案，当UE通过服务通用分组无线业务支持节点（SGSN）连接到服务网关（SGW）时，SGSN和SGW建立UE与PGW之间的承载 。 因此，网络中的每个网络实体的资源被充分利用。

    Wound Heat Exchanger
    43.
    发明申请
    Wound Heat Exchanger 有权
    伤口换热器

    公开(公告)号：US20120197363A1

    公开(公告)日：2012-08-02

    申请号：US13015398

    申请日：2011-01-27

    Applicant: Patrick Cloutier ,  Robert Olsen ,  Stephen Roller ,  Chris Plott ,  Al McLevish ,  Ming Li ,  Michael Laxen ,  John Knoll ,  Gregory Hake

    Inventor： Patrick Cloutier ,  Robert Olsen ,  Stephen Roller ,  Chris Plott ,  Al McLevish ,  Ming Li ,  Michael Laxen ,  John Knoll ,  Gregory Hake

    IPC: A61M1/36 ,  B21D53/02 ,  F28D15/04

    CPC classification number: F28D15/046 ,  A61M1/1698 ,  A61M1/367 ,  A61M1/369 ,  B01D63/025 ,  B01D2313/38 ,  B29C53/083 ,  B29L2031/18 ,  Y10T29/49353

    Abstract: A capillary tube bundle sub-assembly for use in an extracorporeal heat exchanger includes a continuous capillary tubing wound about a core to define a plurality of capillary layers each including a plurality of capillary segments. The capillary segments each define opposing terminal ends adjacent opposing ends of the core. The capillary segments of each layer are circumferentially aligned relative to an axis of the core, with each successive layer being radially outward of an immediately preceding layer. The capillary segments are non-parallel with the axis, spiraling partially about the axis in extension between the opposing terminal ends. Each capillary segment forms less than one complete revolution (i.e., winds less than 360°). The segments within each layer are substantially parallel with one another; however, an orientation of the segments differs from layer-to-layer such as by pitch or angle.

    Abstract translation: 用于体外热交换器的毛细管束子组件包括围绕芯缠绕的连续毛细管，以限定多个毛细管层，每个毛细管层包括多个毛细管段。 毛细管段各自限定与芯的相对端相邻的相对的末端。 每个层的毛细管段相对于芯的轴线周向对准，每个连续层在紧邻的前一层的径向外侧。 毛细管段与轴不平行，部分地围绕相对端部之间延伸的轴线螺旋形。 每个毛细管段形成少于一个完整的旋转（即，风小于360°）。 每个层内的段基本上彼此平行; 然而，片段的取向不同于层间层，例如通过间距或角度。

    Compositions And Methods For Modulating The Pharmacokinetics and Pharmacodynamics of Insulin
    45.
    发明申请
    Compositions And Methods For Modulating The Pharmacokinetics and Pharmacodynamics of Insulin 审中-公开
    用于调节胰岛素的药代动力学和药效学的组合物和方法

    公开(公告)号：US20120178675A1

    公开(公告)日：2012-07-12

    申请号：US13176435

    申请日：2011-07-05

    Applicant: Roderike Pohl ,  Solomon Steiner ,  Robert Hauser ,  Richard Seibert ,  Ming Li

    Inventor： Roderike Pohl ,  Solomon Steiner ,  Robert Hauser ,  Richard Seibert ,  Ming Li

    IPC: A61K38/28 ,  A61P25/00 ,  A61P3/10

    CPC classification number: C07K14/62 ,  A61K9/0019 ,  A61K38/28 ,  A61K47/183

    Abstract: Compositions and methods for modulating the pharmacokinetics and pharmacodynamics of rapid acting injectable insulin formulations are described herein. In the preferred embodiment, the formulations are administered via subcutaneous injection. The formulations contain insulin in combination with a zinc chelator such as ethylenediaminetetraacetic acid (“EDTA”) and a dissolution/stabilization agent, and optionally additional excipients. Calcium disodium EDTA is less likely to remove calcium from the body, and typically has less pain on injection in the subcutaneous tissue. Modulating the type and quantity of EDTA can change the insulin absorption profile. Increasing the quantity of citrate can further enhance absorption and chemically stabilize the formulation. In the preferred embodiment, the formulation contains human insulin, calcium disodium EDTA and a dissolution/stabilization agent such as citric acid or sodium citrate. These formulations are rapidly absorbed into the blood stream when administered by subcutaneous injection.

    Abstract translation: 本文描述了用于调节快速作用的可注射胰岛素制剂的药代动力学和药效学的组合物和方法。 在优选的实施方案中，通过皮下注射施用制剂。 制剂含有与锌螯合剂如乙二胺四乙酸（“EDTA”）和溶解/稳定剂以及任选的其它赋形剂组合的胰岛素。 EDTA二钠不太可能从体内去除钙，并且通常在皮下组织中注射时疼痛较少。 调节EDTA的类型和数量可以改变胰岛素吸收特征。 增加柠檬酸盐的量可以进一步增强吸收和化学稳定制剂。 在优选的实施方案中，制剂含有人胰岛素，EDTA二钠钙和溶解/稳定剂如柠檬酸或柠檬酸钠。 当通过皮下注射给药时，这些制剂被快速地吸收到血流中。

    COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF HEART FAILURE
    49.
    发明申请
    COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF HEART FAILURE 有权
    预防和治疗心脏衰竭的组合物和方法

    公开(公告)号：US20120077762A1

    公开(公告)日：2012-03-29

    申请号：US13377483

    申请日：2010-06-11

    Applicant: Ming Li ,  Zhongyu Li

    Inventor： Ming Li ,  Zhongyu Li

    IPC: A61K31/704 ,  A61P9/00

    CPC classification number: A61K36/00 ,  A61K31/56 ,  A61K31/565 ,  A61K31/7028 ,  A61K31/7032 ,  A61K31/7034 ,  A61K36/23 ,  A61K36/73 ,  A61K2300/00 ,  Y02A50/411

    Abstract: Disclosed herein are compounds, extracts, and active fractions of the plant Geum japonicum alone or in combination with Centella Asiatica and methods for preventing or treating heart failure. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments.

    Abstract translation: 本文公开了单独或与积雪草组合的植物天麻的化合物，提取物和活性级分以及用于预防或治疗心力衰竭的方法。 本文提供的化合物可以配制成在所公开的方法中有用的药物组合物和药物。 还提供了化合物和提取物在制备药物制剂和药物中的用途。

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