公开(公告)号：WO2005057491A8

公开(公告)日：2006-08-03

申请号：PCT/IB2004052569

申请日：2004-11-26

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  BUELOW THOMAS ,  GRASS MICHAEL ,  LORENZ CHRISTIAN ,  MANZKE ROBERT

Inventor： BUELOW THOMAS ,  GRASS MICHAEL ,  LORENZ CHRISTIAN ,  MANZKE ROBERT

IPC: G06T5/00

CPC classification number: G06T7/11 ,  G06T2207/10081 ,  G06T2207/30101

Abstract: Coronary artery segmentation is a crucial task in cardiac CT image processing. This is often a tedious task performed manually by an operator. According to the present invention, a method is provided which combines data from multiple cardiac phases during the segmentation process in order to deliver a complete and continuous coronary vessel tree. Advantageously, this may allow for an improved visualization and segmentation of vessels, for example, in coronary CTA.

Abstract translation: 冠状动脉分割是心脏CT图像处理中的关键任务。 这通常是由操作员手动执行的繁琐的任务。 根据本发明，提供了一种在分割过程中组合来自多个心脏相的数据以递送完整且连续的冠状动脉血管树的方法。 有利地，这可以允许例如在冠状动脉CTA中改善血管的可视化和分割。

公开(公告)号：WO2006018817A3

公开(公告)日：2006-06-15

申请号：PCT/IB2005052714

申请日：2005-08-17

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  GRASS MICHAEL ,  RASCHE VOLKER

Inventor： GRASS MICHAEL ,  RASCHE VOLKER

IPC: A61B6/03

CPC classification number: A61B6/481 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/405 ,  A61B6/4441 ,  A61B6/463 ,  A61B6/466 ,  A61B6/482 ,  A61B6/504

Abstract: The invention relates to a method and an examination apparatus for the evaluation of X-ray projections (31-33, 41-43) that were generated with a rotational X-ray device (10) from different directions and with an energy level varying periodically from projection to projection. Said variation may for example be achieved by a continuously modulated tube voltage (V). Two different 3D-images (35, 45) may be reconstructed from the X-ray projections (31-33, 41-43) which belong to the different energy levels, and said 3D-images may then be compared voxel by voxel in order to segment structures (50) of interest due to contrast differences.

Abstract translation: 本发明涉及一种用于评估X射线投影（31-33,41-43）的方法和检查装置，所述X射线投影由旋转X射线装置（10）从不同方向产生并且能量水平周期性变化 从投影到投影。 所述变化例如可以通过连续调制的管电压（V）来实现。 可以根据属于不同能级的X射线投影（31-33,41-43）重建两个不同的3D图像（35,45），并且然后可以按照体素的顺序将所述3D图像与体素进行比较 由于对比度差异来分割感兴趣的结构（50）。

公开(公告)号：WO02073174A3

公开(公告)日：2003-02-06

申请号：PCT/IB0200697

申请日：2002-03-08

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  GRASS MICHAEL ,  KOEHLER THOMAS ,  PROKSA ROLAND

Inventor： GRASS MICHAEL ,  KOEHLER THOMAS ,  PROKSA ROLAND

IPC: A61B6/03 ,  G01N23/04 ,  G06T11/00

CPC classification number: G01N23/046 ,  A61B6/027 ,  G01N2223/419

Abstract: The invention relates to a computed tomography method for forming images of an object to be examined which is arranged in an examination zone. The examination zone is scanned by means of a conical X-ray beam. In order to enable images having a high image quality to be formed from a selected imaging zone while making an as small as possible computational effort, the invention proposes the following steps: a) selecting an imaging zone of the object to be examined, b) determining the sub-regions of the X-ray detector on which the imaging zone of the object to be examined is projected during the acquisition of the projection data, c) forming sub-projection data by selecting the projection data associated with the sub-regions from the acquired projection data, and d) reconstructing the desired image from the sub-projection data by backprojection.

Abstract translation: 本发明涉及一种用于形成布置在检查区中的被检查物体的图像的计算机断层摄影方法。 检查区域通过锥形X射线束扫描。 本发明提供以下步骤：a）选择待检查对象的成像区域，b）为了使所选择的成像区域能够形成具有高图像质量的图像， 确定在获取投影数据期间投影被检查物体的成像区域的X射线检测器的子区域，c）通过选择与子区域相关联的投影数据来形成子投影数据 并且d）通过反投影从副投影数据重建所需图像。

公开(公告)号：WO2007138526A2

公开(公告)日：2007-12-06

申请号：PCT/IB2007051915

申请日：2007-05-21

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  SCHAEFER DIRK ,  ENGLER ANDREAS ,  MOVASSAGHI BABAK ,  RASCHE VOLKER ,  GRASS MICHAEL

Inventor： SCHAEFER DIRK ,  ENGLER ANDREAS ,  MOVASSAGHI BABAK ,  RASCHE VOLKER ,  GRASS MICHAEL

CPC classification number: A61B6/504 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/481 ,  A61B6/5288 ,  A61B6/541 ,  G06T3/0037 ,  G06T7/20 ,  G06T2207/10081 ,  G06T2207/20016 ,  G06T2207/30101

Abstract: In three-dimensional rotational x-ray coronary imaging problems may arise when estimating the motion of small vessels. According to an exemplary embodiment of the present invention, an examination apparatus is provided which is adapted for performing a hierarchical motion estimation by global affine transformation for every heart phase, followed by vessel branch selective affine and non-affine transformations. This may provide for an improved image quality.

Abstract translation: 在估计小血管运动时可能出现三维旋转X射线冠状动脉成像问题。 根据本发明的示例性实施例，提供了一种检查装置，其适用于通过用于每个心脏相的全局仿射变换执行分层运动估计，随后是血管分支选择仿射和非仿射变换。 这可以提供改进的图像质量。

公开(公告)号：WO2007060572A3

公开(公告)日：2007-10-25

申请号：PCT/IB2006054232

申请日：2006-11-14

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  GRASS MICHAEL ,  SCHAEFER DIRK ,  VAN STEVENDAAL UDO

Inventor： GRASS MICHAEL ,  SCHAEFER DIRK ,  VAN STEVENDAAL UDO

IPC: G06T7/00 ,  A61B5/00 ,  G06T11/00

CPC classification number: A61B6/032 ,  A61B6/027 ,  A61B6/12 ,  A61B6/541 ,  G06T7/20 ,  G06T11/006 ,  G06T2207/10081 ,  G06T2207/30048 ,  G06T2211/412

Abstract: Cardiac CT imaging using gated reconstruction is currently limited in its temporal and spatial resolution. According to an exemplary embodiment of the present invention, an examination apparatus is provided in which an identification of a high contrast object is performed. This high contrast object is then followed through the phases, resulting in a motion vector field of the high contrast object, on the basis of which a motion compensated reconstruction is then performed.

Abstract translation: 使用门控重建的心脏CT成像目前在其时间和空间分辨率方面受到限制。 根据本发明的示例性实施例，提供一种检查装置，其中执行高对比度对象的识别。 然后，该对比度较高的对象随后进入相位，导致高对比度对象的运动矢量场，然后基于此进行运动补偿重建。

公开(公告)号：WO2007054876A2

公开(公告)日：2007-05-18

申请号：PCT/IB2006054119

申请日：2006-11-06

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  KOEHLER THOMAS ,  GRASS MICHAEL

Inventor： KOEHLER THOMAS ,  GRASS MICHAEL

IPC: A61B6/03 ,  A61B6/00

CPC classification number: A61B6/032 ,  A61B5/7289 ,  A61B6/5264

Abstract: An exemplary embodiment of the invention provides a signal processing unit for producing images of an object under examination based on data signals of a tomography system, the signal processing unit comprising a processor and an input interface, wherein the input interface is adapted to receive measured data signals. Furthermore, the processor is adapted to generate a pulmonary gating signal based on said measured data signals and is further adapted to generate an image based on said measured data signals by using the pulmonary gating signal.

Abstract translation: 本发明的示例性实施例提供了一种信号处理单元，用于基于断层摄影系统的数据信号产生被检查对象的图像，信号处理单元包括处理器和输入接口，其中输入接口适于接收测量数据 信号。 此外，处理器适于基于所述测量的数据信号产生肺门控信号，并且还适于通过使用肺门控信号基于所述测量的数据信号生成图像。

公开(公告)号：WO2006117720A2

公开(公告)日：2006-11-09

申请号：PCT/IB2006051285

申请日：2006-04-25

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  PROKSA ROLAND ,  GRASS MICHAEL

Inventor： PROKSA ROLAND ,  GRASS MICHAEL

CPC classification number: G01T1/2985 ,  G01N23/046 ,  G01N2223/419 ,  G01V5/0041 ,  G01V5/005

Abstract: Spectral CT systems require cheap detectors with high energy resolution. According to an aspect of the present invention, a computer tomography apparatus comprises a detector element which is segmented into a plurality of sub-pixels. Each sub-pixel has at least two thresholds and counting channels, wherein the second threshold for each sub-pixel varies over the nominal detector element. This may provide for an improved energy-resolved photon counting.

Abstract translation: 光谱CT系统需要具有高能量分辨率的廉价检测器。 根据本发明的一个方面，一种计算机断层摄影装置包括被分割成多个子像素的检测器元件。 每个子像素具有至少两个阈值和计数通道，其中每个子像素的第二阈值在标称检测器元件上变化。 这可以提供改进的能量分辨光子计数。

公开(公告)号：WO2006106470A2

公开(公告)日：2006-10-12

申请号：PCT/IB2006051004

申请日：2006-04-03

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  GRASS MICHAEL ,  SCHMITT HOLGER

Inventor： GRASS MICHAEL ,  SCHMITT HOLGER

IPC: G06T11/00

CPC classification number: G06T11/008 ,  G06T2211/404 ,  G06T2211/412

Abstract: The present invention relates to image processing device (5) for generating a time series of 3D volume images showing the blood flow in a vascular tree of an object (40), based on a first series of X-ray projection images (D) of the object acquired from different projection directions and a second and a third series of X-ray projections images (E, F) of the object acquired alternately at a first or second fixed projection plane, respectively, during inflow of contrast agent into the vascular tree of the object. In order to allow image reconstruction of unambiguous structures in the object of interest, and, in particular, the generation of 3D volume images showing the blood flow in a vascular tree of an object even if that vascular tree comprises non-tubular structures, such as aneurysms, an image processing device is proposed comprising: a reconstruction unit (51) for reconstruction of a 3D volume image of said object from said first series of X-ray projection images (D), a segmentation unit (52) for segmentation of the vessel tree from said 3D volume image, - a forward projection unit (54) for forward projection of the segmented vessel tree onto said first and projection plane (R 1 , R 2 ), respectively, and a mapping unit (55) for mapping of the image values of pixels of the vessel tree in said second and third, respectively, series of X-ray projection images onto corresponding voxels of said 3D volume image to obtain said time series of 3D volume images showing the blood flow in the vascular tree of the object.

Abstract translation: 本发明涉及一种图像处理装置（5），用于基于第一系列X射线投影图像（D）产生示出物体（40）的血管树中的血流的3D体积图像的时间序列， 在造影剂流入维管束期间，分别在第一或第二固定投影平面上交替地获取的物体从不同的投影方向获取的物体和第二和第三系列的X射线投影图像（E，F） 的对象。 为了允许感兴趣对象中的明确结构的图像重建，并且特别地，生成显示血液流在物体的血管树中的3D体积图像，即使该血管树包括非管状结构，例如 动脉瘤，提出了一种图像处理装置，包括：重建单元（51），用于从所述第一系列X射线投影图像（D）重建所述物体的3D体积图像，分割单元（52），用于分割 来自所述3D体积图像的容器树， - 前向投影单元（54），用于将分割的血管树向前投影到所述第一和投影平面上（R 1，R 2， ）和映射单元（55），用于将所述第二和第三分支X射线投影图像中的血管树的像素的图像值映射到所述3D体积图像的相应体素上，以获得所述时间 系列3D体积图像显示血液 在物体的血管树中流动。

公开(公告)号：WO2006051467A3

公开(公告)日：2006-08-17

申请号：PCT/IB2005053635

申请日：2005-11-07

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  KOEHLER THOMAS ,  GRASS MICHAEL

Inventor： KOEHLER THOMAS ,  GRASS MICHAEL

IPC: A61B6/03

CPC classification number: A61B6/541 ,  A61B6/032 ,  A61B6/4085

Abstract: The invention relates to a computer tomography method for the detection of a cyclically moved object in an examination zone. First, after the acquisition of the measured values, a rough image of the examination zone is reconstructed from which a region relevant for the further method is selected. For the generation of an image with reduced motion artifacts or improved temporal resolution, reconstruction windows in predefinable position are used, which are optimized in such a way that they are, on the one hand, smallest possible, on the other hand, however, sufficiently large, to be able to reconstruct all voxels of this region. Only measured values acquired within the reconstruction windows are taken into account for the reconstruction of a CT image of the region.

Abstract translation: 本发明涉及用于在检查区域中检测循环移动的物体的计算机断层摄影方法。 首先，在获取测量值之后，重建检查区域的粗略图像，从中选择与另一方法相关的区域。 为了生成具有减少的运动伪影或改进的时间分辨率的图像，使用可预定位置中的重建窗口，所述重建窗口被优化为使得它们一方面尽可能最小，另一方面充分地 大，能够重建这个地区的所有体素。 只有在重建窗口内采集的测量值被考虑用于该区域的CT图像的重建。

公开(公告)号：WO2004093684A8

公开(公告)日：2006-03-02

申请号：PCT/IB2004050476

申请日：2004-04-21

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  SCHMITT HOLGER ,  GRASS MICHAEL ,  RASCHE VOLKER

Inventor： SCHMITT HOLGER ,  GRASS MICHAEL ,  RASCHE VOLKER

IPC: A61B6/00

CPC classification number: A61B6/481 ,  A61B6/4441 ,  A61B6/504

Abstract: The invention relates to an X-ray photographic apparatus for imaging the blood flow in the coronary vessel tree of a patient. According to the invention, a first series (1) of X-ray projection images of the coronary tree in various phases of the heart cycle is recorded, at the same time as the ECG (2) of the patient is taken. The three-dimensional structure of the vessel tree in the various phases of the heart cycle is then reconstructed by means of suitable programming means of the computerised portion (17) of the claimed apparatus. A second series (6) of X-ray projection images is recorded while a contrast agent is administered, again at the same time as the ECG (7) is taken. In order to determine the time-dependent contrast agent concentration within the reconstructed three-dimensional structure of the vessel tree, the invention proposes locating local image regions which correspond to individual vessel segments (5, 8) within the X-ray projection images in the second series (6), according to the positions in space of the vessel segments (5, 8) in the relevant phase of the heart cycle. The contrast agent concentration in the area of the vessel segments (5, 8) is then determined by evaluation of X-ray absorption in the thus located local image regions.

Abstract translation: 本发明涉及一种X射线成像装置用于在患者的冠状血管树中的血液流动的可视化。 它是按照本发明采取的，在心动周期的不同阶段的血管树的X射线投影图像中的第一组（1）用ECG的同时记录（2）病人的。 然后，通过计算机的合适的程序的控制手段根据本发明的血管树的三维结构在心动周期的不同阶段的重构装置的装置（17）。 X射线投影图像的第二组（6）的造影剂的给药过程中被记录时，再次记录ECG（7）。 本发明提出以确定所述血管树中，每个容器的段的重构的三维结构内依赖于时间的造影剂浓度（5,8）与（6）对应于所述血管段的在相应的空间位置（8 5），第二组的x射线投影图像中的局部图像区域相关联的 发现心动周期的相位。 然后造影剂浓度的血管段的区域中的确定（5,8）由所述发现局部图像区域内评估Röntgenabsorbtion。