公开(公告)号：WO2006097867A8

公开(公告)日：2008-05-29

申请号：PCT/IB2006050699

申请日：2006-03-07

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  ZIEGLER ANDY ,  KOEHLER THOMAS ,  PROKSA ROLAND

Inventor： ZIEGLER ANDY ,  KOEHLER THOMAS ,  PROKSA ROLAND

IPC: G06T11/00

CPC classification number: G06T11/006 ,  G06T2211/424

公开(公告)号：WO2007129244A3

公开(公告)日：2008-01-10

申请号：PCT/IB2007051525

申请日：2007-04-25

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  FORTHMANN PETER ,  BONTUS CLAAS ,  KOEHLER THOMAS

Inventor： FORTHMANN PETER ,  BONTUS CLAAS ,  KOEHLER THOMAS

IPC: A61B6/03 ,  H01J35/28

CPC classification number: A61B6/032 ,  A61B6/4021 ,  H01J35/101 ,  H01J35/26 ,  H01J35/28 ,  H01J2235/10

Abstract: It is described an X-ray tube (205), in particular for use in computed tomography, comprising an electron source (250), for generating an electron beam (255), an electron deflection device (256) for deflecting the generated electron beam (255), a control unit (257) being coupled to the electron deflection device (256) for spatially controlling the deflection, and an anode (206), which is arranged such that the electron beam (255) impinges onto a focal spot of a surface of the anode (206). Thereby the anode (206) is movable along a z-axis in an oscillating manner, the surface of the anode (206) is oriented oblique with respect to the z-axis, and the control unit (257) is adapted to spatially control the focal spot (255 a) in such a manner that the focal spot moves essentially in a discrete manner between a first focal spot position (106a, 406a) having a first z-coordinate and a second focal spot position (106b, 406b) having a second z-coordinate being different from the first z-coordinate.

Abstract translation: 描述了一种特别用于计算机断层摄影的X射线管（205），包括用于产生电子束（255）的电子源（250），用于使所产生的电子束偏转的电子偏转装置（256） （255），耦合到电子偏转装置（256）的空间控制偏转的控制单元（257）和阳极（206），其布置成使得电子束（255）撞击到 阳极的表面（206）。 因此，阳极（206）可以以振荡方式沿z轴移动，阳极（206）的表面相对于z轴倾斜定向，并且控制单元（257）适于空间控制 焦点（255a），使得焦点基本上以离散的方式移动在具有第一z坐标的第一焦斑位置（106a，406a）和具有第一焦点位置（106b，406b）之间的焦点 第二z坐标与第一z坐标不同。

公开(公告)号：WO2007144830A2

公开(公告)日：2007-12-21

申请号：PCT/IB2007052230

申请日：2007-06-13

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  NIELSEN TIM ,  KOEHLER THOMAS

Inventor： NIELSEN TIM ,  KOEHLER THOMAS

IPC: G02B6/26

CPC classification number: A61B5/4312 ,  A61B5/0091 ,  A61B2560/0233 ,  G01N21/278 ,  G01N21/4795 ,  G01N21/64

Abstract: The invention relates to a device for imaging an interior of a turbid medium and a medical image acquisition device comprising: a) a measurement volume (15) for accommodating the turbid medium (45); b) a light source (5 ) for irradiating the turbid medium (45); c) a photodetector unit 10 for detecting light emanating from the measurement volume (15). The device for imaging an interior of the turbid medium and the medical image acquisition device are adapted such that the devices further comprise a calibration device (55, 60) arranged to be optically coupled to the measurement volume (15) and comprising a calibration light source (65) arranged to simultaneously generate the excitation light and further light corresponding to the fluorescence light. The invention also relates to a calibration device (60) arranged to be inserted into a receptacle (20) that comprises a measurement volume (15) for receiving a turbid medium (45) in a device for imaging an interior of a turbid medium (45), having a contact part (70) comprising a contact surface (75) that fits at least a part of the surface of the receptacle (20) facing the measurement volume (15), and having a calibration light source (65) arranged to simultaneously generate light that causes fluorescent emission in a fluorescent agent present in the turbid medium and further light corresponding to the fluorescence light. The contact part (70) may be removable.

Abstract translation: 本发明涉及一种用于对浑浊介质内部进行成像的装置和医用图像采集装置，包括：a）用于容纳混浊介质的测量体积（15）; b）用于照射混浊介质（45）的光源（5）; c）用于检测从测量体积（15）发出的光的光电检测器单元10。 用于对浑浊介质和医学图像采集装置的内部进行成像的装置适于使得装置还包括校准装置（55,60），该校准装置被布置成光学耦合到测量体积（15），并且包括校准光源 （65），其被布置成同时产生对应于所述荧光的激发光和另外的光。 本发明还涉及一种被布置成插入到容器（20）中的校准装置（60），该容器包括用于在混浊介质（45）的内部成像的装置中接收混浊介质（45）的测量体积 ），其具有接触部分（70），所述接触部分（70）包括接合表面（75），所述接触表面（75）适合面向所述测量体积（15）的所述容器（20）的表面的至少一部分，并且具有校准光源（65） 同时产生在混浊介质中存在的荧光剂中引起荧光发射的光，并且产生对应于荧光的另外的光。 接触部分（70）可以是可移除的。

公开(公告)号：WO2005004063A3

公开(公告)日：2005-12-01

申请号：PCT/IB2004050995

申请日：2004-06-24

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  BONTUS CLASS ,  KOEHLER THOMAS

Inventor： BONTUS CLASS ,  KOEHLER THOMAS

IPC: G06T11/00

CPC classification number: G06T11/005 ,  A61B6/027 ,  G06T11/006 ,  G06T11/008 ,  G06T2211/412 ,  G06T2211/421

Abstract: The invention relates to a computer tomography method in which a radiation source, which emits a cone-shaped beam, moves relative to an investigation area in which an object is arranged, in particular on a helical or circular trajectory. Measured values are acquired with a detector unit, wherein a CT image of the investigation area is reconstructed from these measured values using an nPI reconstruction method, in particular using an exact reconstruction method. In addition, a corrective image is reconstructed from the measured values using an approximative reconstruction method, and added voxel-wise to the CT image.

Abstract translation: 本发明涉及一种计算机断层摄影方法，其中发射锥形束的辐射源相对于其中布置物体的调查区域，特别是在螺旋或圆形轨迹上移动。 使用检测器单元获取测量值，其中使用nPI重建方法，特别是使用精确重建方法，从这些测量值重建调查区域的CT图像。 此外，使用近似重建方法从测量值重建校正图像，并且将体素添加到CT图像。

公开(公告)号：WO2005008597A3

公开(公告)日：2005-08-25

申请号：PCT/IB2004051150

申请日：2004-07-07

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  KOEHLER THOMAS ,  GRASS MICHAEL ,  KUHN MICHAEL HARALD ,  PROKSA ROLAND

Inventor： KOEHLER THOMAS ,  GRASS MICHAEL ,  KUHN MICHAEL HARALD ,  PROKSA ROLAND

IPC: G06T7/20 ,  G06T11/00

CPC classification number: G06T7/20 ,  G06T11/005 ,  G06T2207/10081 ,  G06T2207/30048 ,  G06T2211/404 ,  G06T2211/412

Abstract: In the CT imaging of non-homogeneously moving objects such as the heart or the coronary vessel tree, there is a problem that different parts of the objects are at rest at different points in time. Thus, a gated reconstruction with a globally selected time point does not yield a sharp image of such objects. According to the present invention, a motion of the object is estimated, describing the motion of selected regions of these objects. Then, on the basis of the estimated motion, time points are determined, where these areas have minimal motion. Then, an image is reconstructed, wherein the data from which the respective regions are reconstructed, correspond to the respective time points, where the regions have minimal motion. Due to this, an improved image qualify maybe provided.

Abstract translation: 在诸如心脏或冠状血管树之类的非均匀运动物体的CT成像中，存在不同部分的物体在不同时间点处于静止状态的问题。 因此，具有全局选择的时间点的门控重构不会产生这样的对象的清晰图像。 根据本发明，估计对象的运动，描述这些对象的选定区域的运动。 然后，在估计运动的基础上，确定这些区域具有最小运动的时间点。 然后，重建图像，其中各个区域被重构的数据对应于各个时间点，其中区域具有最小的运动。 因此，可以提供改进的图像资格。

公开(公告)号：WO2010052615A3

公开(公告)日：2011-05-12

申请号：PCT/IB2009054792

申请日：2009-10-28

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  FORTHMANN PETER ,  SCHMITT HOLGER ,  VAN STEVENDAAL UDO ,  KOEHLER THOMAS

Inventor： FORTHMANN PETER ,  SCHMITT HOLGER ,  VAN STEVENDAAL UDO ,  KOEHLER THOMAS

IPC: G06T5/00 ,  G06T7/00 ,  G06T7/20

CPC classification number: G06T11/005 ,  G06T7/11 ,  G06T7/174 ,  G06T7/215 ,  G06T2207/10081 ,  G06T2207/20224 ,  G06T2207/30004 ,  G06T2211/412

Abstract: A method includes creating a second set of projection data that includes substantially only selected structure of interest based on a first set of projection data that includes the selected structure of interest and other structure. Another method includes generating a second plurality of sliding window slices for a last slice of a first plurality of slices, selecting a second sliding window slice from the second plurality of sliding window slices based on the last slice of the first plurality of slices, and generating a second plurality of slices, including a first slice and a last slice, from a range of projection data around projection data corresponding to the last slice of the first plurality of slices.

Abstract translation: 一种方法包括创建第二组投影数据，该投影数据基于包括所选择的感兴趣结构和其他结构的第一组投影数据基本上仅包括所选择的感兴趣结构。 另一种方法包括为第一多个片段的最后片段生成第二多个滑动窗口片段，基于第一多个片段的最后片段从第二多个滑动窗口片段中选择第二滑动窗口片段，以及生成 从与所述第一多个片段的最后片段相对应的投影数据周围的投影数据的范围的第二多个片段，包括第一片段和最后片段。

公开(公告)号：WO2008152593A2

公开(公告)日：2008-12-18

申请号：PCT/IB2008052308

申请日：2008-06-11

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  FORTMANN PETER ,  KOEHLER THOMAS ,  SCHMITT HOLGER

Inventor： FORTMANN PETER ,  KOEHLER THOMAS ,  SCHMITT HOLGER

IPC: G06T11/00

CPC classification number: G06T11/005 ,  A61B6/5258

Abstract: The invention relates to an apparatus for determining a high density region in an image, wherein the apparatus comprises a provision unit (1, 2, 6, 7, 8) for providing projection data for reconstructing the image. The apparatus comprises further a high density shadow determination unit (12) for determining a high density shadow in the projection data and a backprojection unit (13) for backprojecting the determined high density shadow resulting in a high density image showing the high density region. The inventions relates further to a corresponding method and computer program for determining a high density region in an image.

Abstract translation: 本发明涉及一种用于确定图像中的高密度区域的装置，其中所述装置包括用于提供用于重建图像的投影数据的提供单元（1,2,6,7,8）。 该装置还包括用于确定投影数据中的高密度阴影的高密度阴影确定单元（12）和用于反向投影所确定的高密度阴影的反投影单元（13），导致显示高密度区域的高密度图像。 本发明进一步涉及用于确定图像中的高密度区域的相应方法和计算机程序。

公开(公告)号：WO2007113704A3

公开(公告)日：2008-11-06

申请号：PCT/IB2007050896

申请日：2007-03-15

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  KOEHLER THOMAS ,  FORTHMANN PETER

Inventor： KOEHLER THOMAS ,  FORTHMANN PETER

IPC: G06T11/00 ,  G06T7/00

CPC classification number: G06T11/005 ,  A61B6/027 ,  G06T7/30 ,  G06T2207/30004

Abstract: A reconstruction method for an image of an object, the reconstruction method comprising receiving a first projection data set representing information about said object, receiving a second projection data set representing information about said object, reconstructing a first image of said object using the first projection data set, reconstructing a second image of said object using the second projection data set, performing a registration between the first image and the second image, and fusing the first image and the second image to said image of said object, wherein the first projecting data set and the second projecting data set are achieved by using a single radiation type.

Abstract translation: 一种用于对象的图像的重建方法，所述重建方法包括接收表示关于所述对象的信息的第一投影数据集，接收表示关于所述对象的信息的第二投影数据集，使用所述第一投影数据重建所述对象的第一图像 使用所述第二投影数据集重建所述对象的第二图像，执行所述第一图像和所述第二图像之间的对准，以及将所述第一图像和所述第二图像融合到所述对象的所述图像，其中，所述第一投影数据集 并且通过使用单个辐射类型来实现第二投影数据集。

公开(公告)号：WO2008099314A2

公开(公告)日：2008-08-21

申请号：PCT/IB2008050458

申请日：2008-02-08

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  KOEHLER THOMAS ,  FORTHMANN PETER ,  SCHMITT HOLGER

Inventor： KOEHLER THOMAS ,  FORTHMANN PETER ,  SCHMITT HOLGER

CPC classification number: G06T11/005 ,  A61B6/032 ,  A61B6/4233 ,  G06T7/11 ,  G06T7/174 ,  G06T2207/10081 ,  G06T2207/10124 ,  G06T2207/20224 ,  G06T2207/30004

Abstract: The invention relates to an apparatus for determining high density shadows in projection data, wherein the apparatus comprises a first projection data providing unit (1, 2, 3, 6, 7, 8) for providing first projection data, which correspond to a projection through an object having an amount of high density elements. The apparatus comprises further a second projection data providing unit (12) for providing second projection data, which correspond to a projection through a model of the object, in which the amount of high density elements is reduced. The apparatus further comprises a determination unit (13) for determining high density shadows in the first projection data by comparing the first projection data with the second projection data.

Abstract translation: 本发明涉及一种用于确定投影数据中的高密度阴影的装置，其中所述装置包括第一投影数据提供单元（1,2,3,6,7,8），用于提供第一投影数据，所述第一投影数据对应于通过 具有高密度元素量的物体。 该装置还包括第二投影数据提供单元（12），用于提供第二投影数据，第二投影数据对应于通过对象的模型的投影，其中高密度元素的量被减少。 该装置还包括：确定单元，用于通过将第一投影数据与第二投影数据进行比较来确定第一投影数据中的高密度阴影。

公开(公告)号：WO2007031911A3

公开(公告)日：2007-06-07

申请号：PCT/IB2006053144

申请日：2006-09-07

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  NIELSEN TIM ,  KOEHLER THOMAS

Inventor： NIELSEN TIM ,  KOEHLER THOMAS

IPC: A61B5/00

CPC classification number: A61B5/0073 ,  A61B5/14551 ,  A61B5/1495

Abstract: In optical tomography, a calibration of the data may be necessary for image reconstruction. According to an exemplary embodiment of the present invention, the object of interest is used for calibration, wherein the image data is acquired during a highly oxygenated phase of the object of interest and wherein the calibration data is acquired during a low oxygenated phase of the object of interest. This may provide for an improved calibration, resulting in improved image quality.

Abstract translation: 在光学层析成像中，图像重构可能需要校准数据。 根据本发明的示例性实施例，感兴趣的对象被用于校准，其中在感兴趣对象的高度充氧阶段期间获取图像数据，并且其中在对象的低氧合期期间获取校准数据 出于兴趣。 这可以提供改进的校准，导致改善的图像质量。