公开(公告)号：WO2005101277A2

公开(公告)日：2005-10-27

申请号：PCT/IB2005051186

申请日：2005-04-11

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  ECK KAI ,  GROTH ALEXANDRA ,  KIEFER GUNDOLF ,  LEHMANN HELKO ,  BREDNO JOERG ,  WEESE JUERGEN

Inventor： ECK KAI ,  GROTH ALEXANDRA ,  KIEFER GUNDOLF ,  LEHMANN HELKO ,  BREDNO JOERG ,  WEESE JUERGEN

IPC: A61B5/055 ,  A61B6/00 ,  A61B6/03 ,  A61B8/08 ,  A61B10/00 ,  A61B10/02 ,  A61B19/00 ,  G06F19/00

CPC classification number: G06F19/321 ,  A61B5/055 ,  A61B6/03 ,  A61B6/541 ,  A61B8/0833 ,  A61B8/0841 ,  A61B8/463 ,  A61B8/466 ,  A61B10/0233 ,  A61B90/36 ,  G16H50/50

Abstract: In real-time three-dimensional imaging the choice of the visualization method and orientation is crucial for intervention success. The key question is what to ignore and what to show in real-time applications, where user control is not appropriate. The invention addresses this problem by visualizing an intervention (caused by a user) to an object of interest without the requirement of an interactive input by the user. Advantageously, according to an exemplary embodiment of the present invention, parameters for a visualization procedure are automatically chosen during data acquisition which may allow for an efficient tracking of the actual orientation and relative position of the structure with respect to the object of interest.

Abstract translation: 在实时三维成像中，可视化方法和方向的选择对于干预成功至关重要。 关键的问题是什么要忽略，什么显示在实时应用程序，用户控制不合适。 本发明通过将干预（由用户引起）视觉化为感兴趣的对象而不需要用户的交互式输入来解决该问题。 有利地，根据本发明的示例性实施例，在数据获取期间自动选择用于可视化过程的参数，这可以有效地跟踪结构相对于感兴趣对象的实际取向和相对位置。

公开(公告)号：WO2004051579A3

公开(公告)日：2004-08-05

申请号：PCT/IB0305442

申请日：2003-11-27

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  WEESE JUERGEN

Inventor： WEESE JUERGEN

IPC: A61B8/00 ,  A61B8/12 ,  G06T17/00 ,  G06T17/40

CPC classification number: A61B8/12 ,  A61B5/0066 ,  G06T19/00 ,  G06T2210/41

Abstract: The invention relates to the assistance of the navigation of a catheter (1) in a vessel (2). A sequence of cross-sectional images of the portion of the vessel that is of interest is first obtained with the help of an intravascular ultrasound (IVUS) probe (3) and stored as a roadmap of the vessel. A cross-sectional image (10) that is obtained at the current position of the IVUS probe (3) can then be sorted to the position on the roadmap that is the best fit. A model (3') of the probe, and a model (11') of the instrument (a stent (11), for example) coupled to the probe, can be shown on a display (6) at the corresponding position on the roadmap.

Abstract translation: 本发明涉及导管（1）在血管（2）中导航的辅助。 首先通过血管内超声（IVUS）探针（3）的帮助首先获得感兴趣的血管部分的横截面图像序列，并将其存储为血管的路线图。 在IVUS探头（3）的当前位置处获得的横截面图像（10）可以被分类到路线图上最适合的位置。 耦合到探针的探针的模型（3'）和与仪器（例如支架）相连的模型（11'）可以在显示器（6）上显示在 路线图。

公开(公告)号：WO2013088326A3

公开(公告)日：2013-09-19

申请号：PCT/IB2012057137

申请日：2012-12-10

Applicant: KONINKL PHILIPS NV ,  PHILIPS INTELLECTUAL PROPERTY

Inventor： RADULESCU EMIL GEORGE ,  WEESE JUERGEN ,  SALGO IVAN

IPC: A61B8/00 ,  A61B8/08 ,  A61B8/12

CPC classification number: A61B8/0883 ,  A61B8/12 ,  A61B8/145 ,  A61B8/483 ,  A61B8/488 ,  A61B8/5215 ,  A61B8/585

Abstract: Based on anatomy recognition from three-dimensionallive imaging of a volume, one or more portions (204, 208) of the volume are selected in real time. In further real time response, live imaging or the portion(s) is performed with a beam density (156) higher than that used in the volume imaging. The one or more portion may be one or more imaging plane selected for optimal orientation in making an anatomical measurement(424) or display. The recognition can be based on an anatomical model,such as a cardiac mesh model. The model may be pre-encoded with information that can be associated with image locations to provide the basis for portion selection,and for placement of indicia (416, 420, 432, 436) displayable for initiating measurement within an image provided by the live portion imaging. A single TEE or TTE imaging probe (112) may be used throughout. On request, periodically or based on detected motion of the probe with respect to the anatomy, the whole process can be re-executed, starting back from volume acquisition(S508).

Abstract translation: 基于来自体积的三维成像的解剖识别，实时地选择体积的一个或多个部分（204,208）。 在进一步的实时响应中，使用比体积成像中使用的光束密度（156）更高的光束密度（156）进行实时成像或部分。 所述一个或多个部分可以是在进行解剖测量（424）或显示时被选择用于最佳取向的一个或多个成像平面。 识别可以基于解剖模型，例如心脏网格模型。 可以对可以与图像位置相关联的信息对模型进行预编码，以提供部分选择的基础，以及用于放置可由用于在由活体部分提供的图像内启动测量的标记（416,420,432,436） 成像。 可以使用单个TEE或TTE成像探针（112）。 根据请求，定期地或基于探测器相对于解剖结构的检测到的运动，可以从体积获取开始重新执行整个过程（S508）。

公开(公告)号：WO2010018477A3

公开(公告)日：2011-04-07

申请号：PCT/IB2009053192

申请日：2009-07-22

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  SABCZYNSKI JOERG ,  RENISCH STEFFEN ,  CARLSEN INGWER-CURT ,  KABUS SVEN ,  OPFER ROLAND ,  KAUS MICHAEL ,  BZDUSEK KARL ANTONIN ,  WEESE JUERGEN ,  PEKAR VLADIMIR

Inventor： SABCZYNSKI JOERG ,  RENISCH STEFFEN ,  CARLSEN INGWER-CURT ,  KABUS SVEN ,  OPFER ROLAND ,  KAUS MICHAEL ,  BZDUSEK KARL ANTONIN ,  WEESE JUERGEN ,  PEKAR VLADIMIR

IPC: G06F19/00

CPC classification number: G06F19/3481 ,  A61B2034/105 ,  A61B2090/374 ,  A61B2090/3762 ,  A61N5/103 ,  A61N7/02 ,  A61N2005/1041 ,  G06F19/321 ,  G06F19/324 ,  G16H10/60 ,  G16H50/20 ,  G16H50/50

Abstract: A therapy treatment response simulator includes a modeler (202) that generates a model of a structure of an object or subject based on information about the object or subject and a predictor (204) that generates a prediction indicative of how the structure is likely to respond to treatment based on the model and a therapy treatment plan. In another aspect, a system includes performing a patient state determining in silico simulation for a patient using a candidate set of parameters corresponding to another patient and producing a first signal indicative of a predicted state of the patient, and generating a second signal indicative of whether the candidate set of parameters are suitable for the patient based on a known state of the patient.

Abstract translation: 治疗治疗反应模拟器包括基于关于对象或对象的信息生成对象或对象的结构的模型的建模器（202），以及生成表示结构如何响应的预测的预测器（204） 基于模型治疗和治疗方案。 在另一方面，一种系统包括使用与另一患者相对应的参数的候选组来执行患者状态的计算机模拟，并产生指示患者的预测状态的第一信号，以及产生指示是否 基于患者的已知状态，候选参数组适合于患者。

公开(公告)号：WO2009109887A1

公开(公告)日：2009-09-11

申请号：PCT/IB2009050819

申请日：2009-03-02

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINGLIJKE PHILIPS ELECTRONIC ,  MOLLUS SABINE ,  BREDNO JOERG ,  WEESE JUERGEN ,  BABIC DRAZENKO

Inventor： MOLLUS SABINE ,  BREDNO JOERG ,  WEESE JUERGEN ,  BABIC DRAZENKO

IPC: G06T17/00

CPC classification number: G06T17/00 ,  G16H50/50

Abstract: A method of analyzing a tube system in particular by image processing of images of the tube system is provided by the present invention. In order to achieve a simulation of a medium flow through a calculated tube model, the present invention gathers a tube model from a specific tube data set. By defining the necessary parameters of a virtual injection of the medium by the user, the medium flows through the model. Using this displayed simulation for generating at least two images leads to an artificial image sequence that might support a person, which wants to examine a real structure, that corresponds to the calculated model. This might be seen in.

Abstract translation: 通过本发明提供了一种分析管系统的方法，特别是通过管系统的图像的图像处理来分析管系统。 为了通过计算的管模型实现介质流的模拟，本发明从特定的管数据集中收集管模型。 通过定义用户对介质的虚拟注入的必要参数，介质流经模型。 使用该显示的模拟来生成至少两个图像，导致可能支持想要检查与计算出的模型相对应的真实结构的人的人造图像序列。 这可能在。

公开(公告)号：WO2008120177A3

公开(公告)日：2009-01-08

申请号：PCT/IB2008051631

申请日：2008-04-28

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  PETERS JOCHEN ,  ECABERT OLIVIER ,  SCHRAMM HAUKE ,  WEESE JUERGEN ,  BERG JENS VON ,  LORENZ CRISTIAN

Inventor： PETERS JOCHEN ,  ECABERT OLIVIER ,  SCHRAMM HAUKE ,  WEESE JUERGEN ,  BERG JENS VON ,  LORENZ CRISTIAN

IPC: G06T7/00

CPC classification number: G06T7/149 ,  G06T7/12 ,  G06T2207/10072 ,  G06T2207/30048 ,  G06T2207/30101

Abstract: The invention relates to an adaptation system for adapting a deformable model to an object of interest in an image data set, the system comprising a propagator for propagating a set of predetermined transformation parameters to the model segments that have not yet been activated for adaptation to the image; an activator for activating at least one model segment from the model segments that have not yet been activated for adaptation to the image; and an adapter for adapting the deformable model by optimizing model energy of the deformable model, said model energy comprising internal energy of the plurality of model segments and external energy of at least the latest activated model segment(s). By enabling propagation of the transformation parameters from the model segments that have been adapted to the image to the model segments that have not been adapted to the image, this invention can improve the robustness and flexibility of the adaptation.

Abstract translation: 本发明涉及一种用于将可变形模型适应于图像数据集中的感兴趣对象的自适应系统，该系统包括传播器，用于将一组预定变换参数传播到尚未被激活以适应于 图片; 用于激活来自尚未被激活用于适应图像的模型段的至少一个模型段的激活器; 以及用于通过优化所述可变形模型的模型能量来适配所述可变形模型的适配器，所述模型能量包括所述多个模型段的内部能量和至少最近激活的模型段的外部能量。 通过使来自已经适应于图像的模型段的变换参数能够传播到尚未适应于图像的模型段，本发明可以提高适应性的鲁棒性和灵活性。

公开(公告)号：WO2008041165A3

公开(公告)日：2008-11-20

申请号：PCT/IB2007053949

申请日：2007-09-28

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  VON BERG JENS ,  HOFMANN BERND ,  LORENZ CRISTIAN ,  ECABERT OLIVIER ,  PETERS JOCHEN ,  WEESE JUERGEN

Inventor： VON BERG JENS ,  HOFMANN BERND ,  LORENZ CRISTIAN ,  ECABERT OLIVIER ,  PETERS JOCHEN ,  WEESE JUERGEN

IPC: G06T7/00

CPC classification number: G06T7/30 ,  A61B5/055 ,  A61B6/504 ,  A61B6/5229 ,  A61B8/0891 ,  A61B8/5238 ,  G06T2207/20044 ,  G06T2207/30101 ,  Y10S128/922

Abstract: The invention relates to a system (100) for registering a vessel model with an image data set based on a joined model comprising a reference object model and the vessel model, the system comprising: a placement unit (110) for placing the joined model in a space of the image data set, thereby creating a placed joined model comprising a placed reference object model and a placed vessel model; a computation unit (120) for computing a deformation field based on a landmark displacement field comprising displacements of landmarks of the placed reference object model relative to corresponding landmarks in the image data set; a transformation unit (130) for transforming the placed joined model using the deformation field, thereby creating a transformed joined model comprising a transformed reference object model and a transformed vessel model; and a registration unit (140) for registering the transformed vessel model with the image data set based on modifying the transformed vessel model and optimizing an objective function of the modified transformed vessel model, wherein the objective function comprises a location-prior term based on a localization of the modified transformed vessel model relative to the transformed joined model. Hence, the system is arranged to model a vessel taking into account the localization of a vessel model relative to a reference anatomical structure described by a reference model.

Abstract translation: 本发明涉及一种用于基于包括参考对象模型和血管模型的结合模型将血管模型与图像数据集配准的系统（100），所述系统包括：放置单元（110），用于将所述结合模型放入 图像数据集的空间，由此创建包括放置的参考对象模型和放置的船模型的放置的连接模型; 计算单元（120），用于基于地标位移场来计算变形场，所述地标位移场包括所放置的参考对象模型的地标相对于所述图像数据集中的对应地标的位移; 变换单元（130），用于使用所述变形场来变换所放置的结合模型，从而创建包括变换的参考对象模型和变换的血管模型的变换的结合模型; 以及注册单元（140），用于基于修改所述变换的血管模型并优化所述修改的变换的血管模型的目标函数来将所述变换的血管模型与所述图像数据集配准，其中所述目标函数包括基于 修改后的转化血管模型相对于转化的连接模型的定位。 因此，该系统被设置成考虑到血管模型相对于由参考模型描述的参考解剖结构的定位来对血管进行建模。

公开(公告)号：WO2008018014A3

公开(公告)日：2008-04-10

申请号：PCT/IB2007053101

申请日：2007-08-07

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  KIEFER GUNDOLF ,  LEHMANN HELKO ,  GELLER DIETER ,  SCHRAMM HAUKE ,  PETERS JOCHEN ,  ECABERT OLIVIER ,  WEESE JUERGEN

Inventor： KIEFER GUNDOLF ,  LEHMANN HELKO ,  GELLER DIETER ,  SCHRAMM HAUKE ,  PETERS JOCHEN ,  ECABERT OLIVIER ,  WEESE JUERGEN

IPC: G06F19/00

CPC classification number: G16H40/63

Abstract: The invention relates to a system (100) for obtaining information relating to segmented volumetric medical image data, the system comprising: a display unit (110) for displaying a view of the segmented volumetric medical image data on a display; an indication unit (115) for indicating a location on the displayed view; a trigger unit (120) for triggering an event; an identification unit (125) for identifying a segmented anatomical structure comprised in the segmented volumetric medical image data based on the indicated location on the displayed view in response to the triggered event; and an execution unit (130) for executing an action associated with the identified segmented anatomical structure, thereby obtaining information relating to the segmented volumetric medical image data. The action executed by the execution unit (130) may be displaying a name of the segmented anatomical structure, a short description of the segmented anatomical structure, or a hint on a potential malformation or malfunction of the segmented anatomical structure. Thus, the system (100) allows obtaining valuable information relating to the volumetric medical image data viewed by a physician on the display, thereby assisting the physician in medical diagnosing.

Abstract translation: 本发明涉及一种用于获取与分段体积医学图像数据相关的信息的系统（100），该系统包括：显示单元（110），用于在显示器上显示分割的体积医学图像数据的视图; 指示单元（115），用于指示所显示的视图上的位置; 触发单元（120），用于触发事件; 识别单元（125），用于响应于触发的事件，基于所显示的视图上的指示位置来识别包含在所述分段体积医学图像数据中的分段解剖结构; 以及执行单元（130），用于执行与所识别的分段解剖结构相关联的动作，从而获得与分割的体积医学图像数据相关的信息。 由执行单元（130）执行的动作可以显示分割的解剖结构的名称，分割的解剖结构的简短描述，或对分割的解剖结构的潜在畸形或故障的提示。 因此，系统（100）允许获得与医生在显示器上观看的体积医学图像数据相关的有价值的信息，从而辅助医师进行医学诊断。

公开(公告)号：WO2008015611A2

公开(公告)日：2008-02-07

申请号：PCT/IB2007052854

申请日：2007-07-18

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  MOLLUS SABINE ,  WEESE JUERGEN ,  WIEGERT JENS ,  HOMAN ROBERT JOHANNES FREDERIK

Inventor： MOLLUS SABINE ,  WEESE JUERGEN ,  WIEGERT JENS ,  HOMAN ROBERT JOHANNES FREDERIK

IPC: A61B6/00

CPC classification number: A61B6/488 ,  A61B6/03 ,  A61B6/4441 ,  A61B6/469 ,  Y10S378/901

Abstract: In three-dimensional X-ray imaging, with C-arm systems, scan setup has to be performed manually under fluoroscopic control. According to an exemplary embodiment of the present invention, a scan planning system for planning a data acquisition process is provided, which is adapted to predict a field of view to be reconstructed and an image quality in the field of view with respect to the actual three- dimensional scan parameter set and previously acquired images or other information. The scan planning system may be accomplished by a stand control unit.

Abstract translation: 在三维X射线成像中，使用C型臂系统时，必须在透视控制下手动执行扫描设置。 根据本发明的示例性实施例，提供了一种用于规划数据获取过程的扫描计划系统，该扫描计划系统适于预测将被重构的视场和相对于实际的三个视场中的视场中的图像质量 - 二维扫描参数组和先前获取的图像或其他信息。 扫描计划系统可以由台架控制单元完成。

公开(公告)号：WO2007069223A3

公开(公告)日：2007-09-27

申请号：PCT/IB2006054894

申请日：2006-12-15

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  BERG JENS VON ,  GERRITSEN FRANS ANDREAS ,  WEESE JUERGEN ,  LORENZ CRISTIAN ,  PETERS JOCHEN ,  ECABERT OLIVIER

Inventor： BERG JENS VON ,  GERRITSEN FRANS ANDREAS ,  WEESE JUERGEN ,  LORENZ CRISTIAN ,  PETERS JOCHEN ,  ECABERT OLIVIER

IPC: G06T17/10 ,  G06T17/20

CPC classification number: G06T17/20 ,  G06T17/10 ,  G06T17/205

Abstract: The invention relates to a method (100) of and to a system (200) for determining a template mesh of a shape model on the basis of a plurality of instances of the shape model. The method of determining the template mesh of the shape model comprises an obtaining step (110) for obtaining the plurality of instances of the template mesh, a computing step (120) for computing a plurality of results on the basis of the plurality of instances of the shape model, a deciding step (130) for deriving a decision on the basis of the plurality of results, and a decimating step (140) for decimating the template mesh of the shape model on the basis of the decision, thereby determining the template mesh of the shape model. Thus, the template mesh of the shape model determined by the method of the invention better describes objects of interest at all locations.

Abstract translation: 本发明涉及用于基于形状模型的多个实例来确定形状模型的模板网格的系统（200）的方法（100）。 确定形状模型的模板网格的方法包括：获得步骤（110），用于获得模板网格的多个实例;计算步骤（120），用于基于多个实例的 形状模型，用于基于多个结果导出决定的决定步骤（130），以及用于基于该决定抽取形状模型的模板网格的抽取步骤（140），由此确定模板 形状模型的网格。 因此，通过本发明的方法确定的形状模型的模板网格更好地描述了在所有位置处感兴趣的对象。