公开(公告)号：US20100144052A1

公开(公告)日：2010-06-10

申请号：US12305950

申请日：2006-12-11

Applicant: Bo Pi

Inventor： Bo Pi

IPC: G01N21/75 ,  G01N21/01 ,  G01N21/03 ,  G01N21/17

CPC classification number: G01N21/253 ,  G01N21/274 ,  G06F19/00

Abstract: Optical detection of molecules using a biochip having at least one reagent immobilizing area designed to receive one or more reagents and at least one calibration structure with a predetermined height to provide a height reference for optical measurement is disclosed. When the calibration structure is illuminated by a probe beam of light, a first reflected beam of light is reflected off the calibration structure, and a second reflected beam of light is reflected off the reagent immobilizing area. The first reflected beam and the second reflected beam are compared to determine a height at the reagent immobilizing area.

Abstract translation: 公开了使用具有设计成接收一种或多种试剂的至少一个试剂固定区域和具有预定高度的至少一个校准结构以提供用于光学测量的高度参考的生物芯片的分子的光学检测。 当校准结构被探测光束照射时，第一反射光束从校准结构反射，第二反射光束从试剂固定区域反射出来。 比较第一反射光束和第二反射光束以确定试剂固定区域的高度。

公开(公告)号：US07085452B1

公开(公告)日：2006-08-01

申请号：US10804279

申请日：2004-03-18

Applicant: Wei-Cheng Wilson Lin ,  Bo Pi

Inventor： Wei-Cheng Wilson Lin ,  Bo Pi

IPC: G02B6/26 ,  G02B6/42

CPC classification number: G02B6/4215 ,  G01K11/32 ,  G01N21/7746 ,  G02B6/022 ,  G02B6/2852 ,  G02B6/29341 ,  G02B6/30 ,  G02B6/34 ,  G02B2006/12107

Abstract: Optical devices having at least one whispering gallery mode cavity formed on a side-polished coupling port of a fiber or waveguide based on evanescent coupling are described.

Abstract translation: 描述了在基于ev逝耦合的光纤或波导的侧面抛光耦合端口上形成有至少一个耳语画廊模式空腔的光学装置。