公开(公告)号：KR101810078B1

公开(公告)日：2017-12-18

申请号：KR1020160176593

申请日：2016-12-22

Applicant: 주식회사 에타맥스

Inventor： 정현돈 ,  김영범 ,  김정민

IPC: G01N21/64 ,  G01N21/88 ,  G01N27/10

CPC classification number: G01N21/6489 ,  G01N21/8806 ,  G01N27/10 ,  G01N2021/6495 ,  G01N2021/8845 ,  G01N2201/06113 ,  G01N2201/0662

Abstract: 본발명은기판내부의결함은광루미네선스로검출하고기판외부의결함은광루미네선스발생용입사광의산란을이용해검출하는기판결함측정장치에관한것으로, 광루미네선스를측정하는과정에서산란및/또는반사광을함께측정할수 있도록광학계를구성하여측정시간을단축하는장치를제공한다.

Abstract translation: 本发明涉及一种基板缺陷测量装置，用于通过光学发光来检测基板内部的缺陷并且通过使用入射光的散射来检测基板外部的缺陷以产生发光发光， 和/或通过构建光学系统缩短测量时间的装置，以便可以一起测量反射光。

公开(公告)号：KR100580622B1

公开(公告)日：2006-05-16

申请号：KR1020030017137

申请日：2003-03-19

Applicant: 삼성전자주식회사

Inventor： 전계진 ,  윤길원 ,  황인덕 ,  한상준

IPC: A61B5/145

CPC classification number: A61B5/14532 ,  A61B5/0053 ,  A61B5/107 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B2560/0223 ,  G01N21/359 ,  G01N2021/036 ,  G01N2021/3144 ,  G01N2201/0662

Abstract: 비침습적 혈액성분 측정방법 및 장치가 개시된다. 비침습적 혈액성분 측정방법은 (a) 소정의 과도압력에 해당하는 초기두께보다 두꺼운 범위에서, 피검체의 측정하고자 하는 특정 부위의 두께를 가변시키고, 가변된 각 두께에서 측정된 흡수 스펙트럼들의 차이 흡수 스펙트럼과 실측된 특정 혈액성분의 농도를 이용하여 상기 혈액성분에 대한 통계모델을 수립하는 단계, 및 (b) 상기 통계모델에 근거하여, 상기 피검체의 특정 부위에서 측정된 차이 흡수 스펙트럼으로부터 해당 혈액성분을 예측하는 단계로 이루어진다.

公开(公告)号：US20190195770A1

公开(公告)日：2019-06-27

申请号：US16196479

申请日：2018-11-20

Applicant: MINITÜB GMBH

Inventor： Georg WIPPENBECK ,  Christian SIMMET

IPC: G01N15/14 ,  C12Q1/06 ,  B01L3/00 ,  G02B21/34

CPC classification number: G01N15/1404 ,  B01L3/5027 ,  B01L2200/021 ,  B01L2200/026 ,  B01L2200/14 ,  C12Q1/06 ,  G01N15/06 ,  G01N2015/0693 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2201/0662 ,  G02B21/16 ,  G02B21/34

Abstract: The present invention relates to a method for analyzing samples comprising spermatozoa, said method comprising the use of a flow-through counting compartment, wherein the time period between the end of loading and closing is carried out in a controlled and specified time period. The present invention further relates to a counting compartment or chamber suitable for said method and to a counting device comprising said counting compartment.

公开(公告)号：US09678010B2

公开(公告)日：2017-06-13

申请号：US14317070

申请日：2014-06-27

Applicant: MSA TECHNOLOGY, LLC.

Inventor： Christopher D. Starta ,  Robert E. Uber ,  Thomas Trautzsch ,  Frederick J. Schuler

IPC: G01N21/3504 ,  G01N21/59 ,  G01N21/31

CPC classification number: G01N21/59 ,  G01N21/3151 ,  G01N21/3504 ,  G01N2201/023 ,  G01N2201/0636 ,  G01N2201/0662

Abstract: A closed path infrared sensor includes an enclosure, a first energy source within the enclosure, at least a second energy source within the enclosure, at least one detector system within the enclosure and a mirror system external to the enclosure and spaced from the enclosure. The mirror system reflects energy from the first energy source to the at least one detector system via a first analytical path and reflects energy from the second energy source to the at least one detector system via a second analytical path. Each of the first analytical path and the second analytical path are less than two feet in length.

公开(公告)号：US09638608B2

公开(公告)日：2017-05-02

申请号：US15112792

申请日：2015-06-30

Applicant: Beacon Technologies, LLC

Inventor： Dale Lee Heintzelman, Jr.

IPC: G01N1/10 ,  G01N1/14 ,  G01N35/10 ,  B01L3/02 ,  G01N21/01

CPC classification number: B01L3/0275 ,  B01L3/021 ,  B01L9/543 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2300/0654 ,  B01L2300/0858 ,  B01L2300/123 ,  B01L2300/168 ,  G01N1/14 ,  G01N21/01 ,  G01N21/0303 ,  G01N21/13 ,  G01N21/59 ,  G01N35/10 ,  G01N2021/0367 ,  G01N2035/1062 ,  G01N2201/0662

Abstract: This disclosure is directed to exemplary embodiments of systems, methods, techniques, processes, products and product components that can facilitate users making improved absorbance or fluorescence measurements in the field of spectroscopy with reduced (minimal) sample waste, and increased throughput, particularly in the study of biological sciences. A measuring system is provided having: a base unit with a means for locating a pipette tip; a pipette tip designed to interact with the base unit for purposes of accurate pipette tip positioning; at least one light supplying unit positioned to supply light to a liquid sample in the pipette tip and at least one light collecting unit positioned to collect light from a liquid sample in the pipette tip.

公开(公告)号：US20140231680A1

公开(公告)日：2014-08-21

申请号：US14174964

申请日：2014-02-07

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Darko Klinec

IPC: G01N33/49

CPC classification number: G01N33/491 ,  G01N15/06 ,  G01N21/13 ,  G01N21/253 ,  G01N21/3151 ,  G01N21/51 ,  G01N35/02 ,  G01N35/1016 ,  G01N2015/045 ,  G01N2015/0693 ,  G01N2035/0406 ,  G01N2035/1018 ,  G01N2201/066 ,  G01N2201/0662 ,  G01N2201/0668

Abstract: A method for detecting clots in a liquid is presented. The liquid is in a sample container. Light is irradiated having a first wavelength to the sample container by a first light source at a changeable vertical irradiating position (P—0 to P_n) such that the light irradiated by the first light source passes through the sample container along a first measurement path. An intensity of light having the first wavelength passing along the first measurement path and exiting the sample container is measured. Clots are detected in response to the measured intensity.

Abstract translation: 提出了一种用于检测液体中凝块的方法。 液体在样品容器中。 通过在可变的垂直照射位置（P-0至P_n）处的第一光源将具有第一波长的光照射到第一光源，使得由第一光源照射的光沿第一测量路径通过样品容器。 测量具有沿着第一测量路径通过并离开样品容器的第一波长的光的强度。 根据测量的强度检测到凝块。

公开(公告)号：US08213016B2

公开(公告)日：2012-07-03

申请号：US12805071

申请日：2010-07-12

Applicant: Andreas Muller ,  Rudiger Frank

Inventor： Andreas Muller ,  Rudiger Frank

IPC: G01N21/00

CPC classification number: G01N21/53 ,  G01N15/06 ,  G01N21/274 ,  G01N2015/0693 ,  G01N2201/061 ,  G01N2201/0662

Abstract: A turbidity measuring device having a four-beam, alternating light arrangement for registering turbidity of a measured medium includes first and second light sources L1, L2; and first and second receivers R1, R2. The direct measuring paths extend from light sources Li, through a measured medium, to receivers Ri, and indirect measuring paths extend from light sources Li, through the measured medium, to second receivers Rj; wherein i≠j; wherein turbidity can be ascertained as a function of a quotient A/B by means of an evaluating circuit; wherein A and B are functions at least of signals registered via the direct or indirect measuring paths; wherein at least a first monitor signal, which depends on the first light source, enters into one of the two terms A or B; wherein the light reaches the monitor from the first light source without interaction with the measured medium; and wherein the monitor signal is added to at least one of the signals registered via the measuring paths and entering into the term A or B.

Abstract translation: 具有用于记录测量介质的浊度的四光束交替光布置的浊度测量装置包括第一和第二光源L1，L2; 以及第一和第二接收器R1，R2。 直接测量路径从光源Li延伸通过测量介质到接收器Ri，并且间接测量路径从光源Li延伸通过测量的介质到第二接收器Rj; 其中i≠j; 其中可以通过评估电路将浊度确定为商A / B的函数; 其中A和B至少是经由直接或间接测量路径登记的信号的功能; 其中依赖于第一光源的至少第一监视信号进入两个项A或B中的一个; 其中所述光从所述第一光源到达所述监视器，而不与所述测量介质相互作用; 并且其中所述监视信号被添加到经由所述测量路径登记的信号中的至少一个并输入到所述术语A或B.

公开(公告)号：US20110172513A1

公开(公告)日：2011-07-14

申请号：US13063703

申请日：2009-11-09

Applicant: Takao Nakajima ,  Kazuhiko Fukutani

Inventor： Takao Nakajima ,  Kazuhiko Fukutani

IPC: A61B5/05

CPC classification number: G01N21/1702 ,  A61B5/0059 ,  A61B5/0095 ,  A61B5/02007 ,  G01N2201/0662

Abstract: The biological information imaging apparatus includes an acoustic wave detector 107 that detects an acoustic wave that is generated from a light absorber 105 and converts it to a first electrical signal; a photo-detector 110 that detects intensities of the light corresponding to a plurality of propagation distances of the light which propagates through the specimen 110 and converts it to a second electrical signal; a signal processing apparatus 111 that derives an average effective attenuation coefficient μeff of the specimen 110 based on the second electrical signal and derives an optical absorption coefficient μa of the specimen 110 based on the first electrical signal and the average effective attenuation coefficient μeff; and an image constructing apparatus 111 that constructs an image of the distribution of the optical absorption coefficient μa based on the distribution of the optical absorption coefficient μa.

Abstract translation: 生物信息成像装置包括声波检测器107，其检测从光吸收体105产生的声波并将其转换为第一电信号; 光检测器110，其检测与通过样本110传播的光的多个传播距离相对应的光的强度，并将其转换为第二电信号; 信号处理装置111，其基于第二电信号导出样本110的平均有效衰减系数μeff，并根据第一电信号和平均有效衰减系数μeff导出样本110的光吸收系数μa; 以及基于光吸收系数μa的分布构建光吸收系数μa的分布的图像的图像构造装置111。

公开(公告)号：US20110019194A1

公开(公告)日：2011-01-27

申请号：US12805071

申请日：2010-07-12

Applicant: Andreas Müller ,  Rüdiger Frank

Inventor： Andreas Müller ,  Rüdiger Frank

IPC: G01N21/00

CPC classification number: G01N21/53 ,  G01N15/06 ,  G01N21/274 ,  G01N2015/0693 ,  G01N2201/061 ,  G01N2201/0662

Abstract: A turbidity measuring device having a four-beam, alternating light arrangement for registering turbidity of a measured medium includes first and second light sources L1, L2; and first and second receivers R1, R2. The direct measuring paths extend from light sources Li, through a measured medium, to receivers Ri, and indirect measuring paths extend from light sources Li, through the measured medium, to second receivers Rj; wherein i≠j; wherein turbidity can be ascertained as a function of a quotient A/B by means of an evaluating circuit; wherein A and B are functions at least of signals registered via the direct or indirect measuring paths; wherein at least a first monitor signal, which depends on the first light source, enters into one of the two terms A or B; wherein the light reaches the monitor from the first light source without interaction with the measured medium; and wherein the monitor signal is added to at least one of the signals registered via the measuring paths and entering into the term A or B.

Abstract translation: 具有用于记录测量介质的浊度的四光束交替光布置的浊度测量装置包括第一和第二光源L1，L2; 以及第一和第二接收器R1，R2。 直接测量路径从光源Li延伸通过测量介质到接收器Ri，并且间接测量路径从光源Li延伸通过测量的介质到第二接收器Rj; 其中i≠j; 其中可以通过评估电路将浊度确定为商A / B的函数; 其中A和B至少是经由直接或间接测量路径登记的信号的功能; 其中依赖于第一光源的至少第一监视信号进入两个项A或B中的一个; 其中所述光从所述第一光源到达所述监视器，而不与所述测量介质相互作用; 并且其中所述监视信号被添加到经由所述测量路径登记的信号中的至少一个并输入到所述术语A或B.

公开(公告)号：US07796261B2

公开(公告)日：2010-09-14

申请号：US11792097

申请日：2005-12-01

Applicant: Henrik Vilstrup Juhl

Inventor： Henrik Vilstrup Juhl

IPC: G01N21/00

CPC classification number: G01N21/0303 ,  G01N21/31 ,  G01N2021/036 ,  G01N2201/066 ,  G01N2201/0662 ,  G01N2201/1293

Abstract: A spectrophotometer (2) comprising a source of radiation (6), preferably optical radiation, disposed to emit radiation at a plurality of wavelengths towards a sample in a sample holder (4) and a detection arrangement 8 for detecting the radiation after its interaction with the sample. The sample holder (4) is adapted to present a plurality of different path lengths for the emitted radiation through the sample. An arithmetic unit (10;10b) is operably connected to receive an intensity dependent output from the detection arrangement (8) and is adapted to store an intensity value of the detected emitted radiation indexed to its wavelength at two or more path lengths of the plurality of different path lengths and to calculate a value dependent on the ratio of the indexed intensity values at each of two path lengths by which an indication of the presence of a substance of interest withiA spectrophotometer (2) comprise a source of radiation (6), preferably optical radiation, disposed to emit radiation at a plurality of wavelengths towards a sample in a sample holder (4) and a detection arrangement 8 for detecting the radiation after its interaction with the sample. The sample holder (4) is adapted to present a plurality of different path lengths for the emitted radiation through the sample. An arithmetic unit (10;10b) is operably connected to receive an intensity dependent output from the detection arrangement (8) and is adapted to store an intensity value of the detected emitted radiation indexed to its wavelength at two or more path lengths of the plurality of different path lengths and to calculate a value dependent on the ratio of the indexed intensity values at each of two path lengths by which an indication of the presence of a substance of interest within the retained sample can be obtained.

Abstract translation: 一种分光光度计（2），包括辐射源（6），优选光辐射，被设置成朝向样品保持器（4）中的样品发射多个波长的辐射;以及检测装置8，用于在与 例子。 样品保持器（4）适于对通过样品的发射辐射呈现多个不同的路径长度。 算术单元（10; 10b）可操作地连接以接收来自检测装置（8）的与强度相关的输出，并且适于将检测到的发射的辐射的强度值存储在其波长的两个或更多个路径长度上 并且计算取决于两个路径长度中的每一个处的索引强度值的比率的值，通过该值，用分光光度计（2）存在感兴趣的物质的指示包括辐射源（6）， 优选地，光辐射被设置为以多个波长朝向样品保持器（4）中的样品发射辐射;以及检测装置8，用于在与样品相互作用之后检测辐射。 样品保持器（4）适于对通过样品的发射辐射呈现多个不同的路径长度。 算术单元（10; 10b）可操作地连接以接收来自检测装置（8）的与强度相关的输出，并且适于将检测到的发射的辐射的强度值存储在其波长的两个或更多个路径长度上 并且计算取决于两个路径长度中的每一个处的索引强度值的比率的值，通过该值，可以获得在保留的样品内存在感兴趣物质的指示。