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    SYSTEMS, APPARATUSES, AND METHODS FOR ASSESSMENT OF LONG TERM STABILITY OF SAMPLES
    41.
    发明申请
    SYSTEMS, APPARATUSES, AND METHODS FOR ASSESSMENT OF LONG TERM STABILITY OF SAMPLES 审中-公开
    用于评估样品长期稳定性的系统，装置和方法

    公开(公告)号：WO2017151637A1

    公开(公告)日：2017-09-08

    申请号：PCT/US2017/019980

    申请日：2017-02-28

    Applicant: UNCHAINED LABS

    Inventor： FREIRE, Ernesto ,  BROWN, Richard

    IPC: G01N21/64 ,  G01N33/52 ,  G01N33/62 ,  G01N33/68 ,  A61B5/00

    CPC classification number: G01N33/68 ,  G01N21/6486 ,  G01N21/75 ,  G01N33/62 ,  G01N2021/755 ,  G01N2201/122

    Abstract: A method includes receiving a sample. The method also includes applying a denaturing agent to a first portion of the sample, and detecting, in response to the application of the denaturing agent, a first measure from the first portion of the sample. The method also includes modifying the temperature of a second portion of the sample and detecting, in response to the modifying the temperature of the second portion of the sample, a second measure from the second portion of the sample. The method also includes computing thermodynamic information for the sample based on the indication of the first measure, and computing kinetic information for the sample based on the indication of the second measure. The method also includes computing, based on the thermodynamic information and the kinetic information, an indication of temporal stability of the protein component of the sample.

    Abstract translation: 一种方法包括接收样本。 该方法还包括将变性剂施加到样品的第一部分，并且响应于变性剂的施加，检测来自样品的第一部分的第一量度。 该方法还包括修改样品的第二部分的温度并且响应于修改样品的第二部分的温度而从样品的第二部分检测第二测量。 该方法还包括基于第一测量的指示计算样本的热力学信息，并且基于第二测量的指示计算样本的动力学信息。 该方法还包括基于热力学信息和动力学信息计算样品的蛋白质组分的时间稳定性的指示。

    METHODS AND SYSTEMS FOR IN SITU PHYSICOCHEMICAL PROPERTY TESTING
    42.
    发明申请
    METHODS AND SYSTEMS FOR IN SITU PHYSICOCHEMICAL PROPERTY TESTING 审中-公开
    在物理化学性质测试中的方法和系统

    公开(公告)号：WO2009088781A1

    公开(公告)日：2009-07-16

    申请号：PCT/US2008/088211

    申请日：2008-12-23

    Applicant: PION INC. ,  AVDEEF, Alex ,  VOLOBOY, Dmytro ,  DOHODA, Deren, J. ,  NIELSEN, Per, E. ,  DEMARIA, Michael, J.

    Inventor： AVDEEF, Alex ,  VOLOBOY, Dmytro ,  DOHODA, Deren, J. ,  NIELSEN, Per, E. ,  DEMARIA, Michael, J.

    IPC: G01N33/15

    CPC classification number: G01N21/253 ,  G01N21/0332 ,  G01N21/272 ,  G01N21/82 ,  G01N2201/122

    Abstract: An apparatus for evaluating physicochemical properties of sample materials contained in an array of vessels includes: a light detector; a light source for transmitting a light beam through the sample material in a vessel to the light detector; an analyzer for processing data from the light detector to determine concentration-related properties of the sample material as a function of time; and a mixing system. The mixing system includes: a plurality of magnetic stirrer elements, each for being placed in a sample material in a different one of the array of vessels; an array of magnetic drive elements, each associated with a different one of the array of vessels and being magnetically coupled with a magnetic stirrer element in an associated vessel; and a drive mechanism coupled to the array of magnetic drive elements for simultaneously moving each of the magnetic drive elements relative to an associated vessel.

    Abstract translation: 用于评估包含在容器阵列中的样品材料的物理化学性质的装置包括：光检测器; 用于将光束通过容器中的样品材料传输到光检测器的光源; 用于处理来自光检测器的数据的分析器，以确定作为时间的函数的样品材料的浓度相关性质; 和混合系统。 混合系统包括：多个磁力搅拌器元件，每个磁力搅拌器元件被放置在不同容器阵列中的样品材料中; 一组磁性驱动元件，每个磁性驱动元件与不同的容器阵列相关联并且与相关联的容器中的磁力搅拌器元件磁耦合; 以及耦合到磁驱动元件阵列的驱动机构，用于相对于相关联的容器同时移动每个磁驱动元件。

    A HANDHELD DEVICE WITH A DISPOSABLE ELEMENT FOR CHEMICAL ANALYSIS OF MULTIPLE ANALYTES
    43.
    发明申请
    A HANDHELD DEVICE WITH A DISPOSABLE ELEMENT FOR CHEMICAL ANALYSIS OF MULTIPLE ANALYTES 审中-公开
    具有多种分析物化学分析的可拆卸元件的手持装置

    公开(公告)号：WO2005073696A1

    公开(公告)日：2005-08-11

    申请号：PCT/US2005/000092

    申请日：2005-01-04

    Applicant: GENERAL ELECTRIC COMPANY ,  XIAO, Caibin ,  BOYETTE, Scott, M. ,  POTYRAILO, Radislav, A.

    Inventor： XIAO, Caibin ,  BOYETTE, Scott, M. ,  POTYRAILO, Radislav, A.

    IPC: G01N21/55

    CPC classification number: G01N21/7703 ,  G01N21/253 ,  G01N21/272 ,  G01N21/274 ,  G01N21/314 ,  G01N21/552 ,  G01N21/8483 ,  G01N2021/7783 ,  G01N2021/8488 ,  G01N2201/0221 ,  G01N2201/0245 ,  G01N2201/0461 ,  G01N2201/122

    Abstract: A portable system and method for measuring the concentration of multiple chemical or biological substances where an onsite analysis of such substances is needed. The new and original handheld sensor system uses a disposable optical test element and a spectroscopic detector that measures the test element response to specific analytes through a change in light absorbance, luminescence, and other forms of light-based response. In this way, reflection light intensities indicative of the test element response can be used to measure the concentration of the target analytes. The sensor system is also capable of being interfaced to an information processing unit or computer so that analytical data can be manipulated or stored electronically.

    Abstract translation: 用于测量需要对这些物质进行现场分析的多种化学或生物物质的浓度的便携式系统和方法。 新的和原始的手持传感器系统使用一次性光学测试元件和光谱检测器，其通过光吸收，发光和其他形式的基于光的响应的变化来测量测试元件对特定分析物的响应。 以这种方式，可以使用指示测试元件响应的反射光强度来测量目标分析物的浓度。 传感器系统还能够连接到信息处理单元或计算机，从而可以电子地操纵或存储分析数据。

    에칭 모니터 방법 및 장치
    46.
    发明授权
    에칭 모니터 방법 및 장치 失效
    用于监测蚀刻的方法和装置

    公开(公告)号：KR1019900000613B1

    公开(公告)日：1990-02-01

    申请号：KR1019850003560

    申请日：1985-05-23

    Applicant: 가부시끼가이샤 히다치 세이사꾸쇼

    Inventor： 오가와요시후미 ,  니시우미마사하루 ,  다나까요시에 ,  오꾸다이라사다유끼 ,  니시마쓰시게루

    IPC: H01L21/145

    CPC classification number: H01J37/32935 ,  G01N21/62 ,  G01N2201/122

    Abstract: (i) regulating gas pressure in a treating chamber, where a sample is being dry etched at a pressure at which a clear emission line spectrum can be contained; (ii) converting the gas to a plasma; and (iii) monitoring the etching state of the sample from the change of intensity of the emission line spectrum of the plasma with time. The monitoring apparatus comprises (a) an wxhaust discharging gas from the treating chamber to a subchamber; (b) a plasma generator converting the discharged gas to a plasma; (c) a pressure regulator regulating fag pressure in the subchamber; and (d) a spectrum detector for detecting the emission line spectrum of the plasma and changes in its intensity with time.

    Abstract translation: （i）调节处理室中的气体压力，其中样品在可以包含清晰发射线光谱的压力下被干蚀刻; （ii）将气体转化为等离子体; 和（iii）随着时间从等离子体的发射谱线的强度的变化监测样品的蚀刻状态。 监测装置包括（a）从处理室向子室排放废气; （b）等离子体发生器将排出的气体转换成等离子体; （c）压力调节器调节子室内的压力; 和（d）用于检测等离子体的发射谱线的频谱检测器和其强度随时间的变化。

    SPECTROSCOPY APPARATUS AND METHODS
    49.
    发明申请
    SPECTROSCOPY APPARATUS AND METHODS 审中-公开
    光谱仪器和方法

    公开(公告)号：WO2015049494A1

    公开(公告)日：2015-04-09

    申请号：PCT/GB2014/052937

    申请日：2014-09-30

    Applicant: RENISHAW PLC

    Inventor： MASON, Thomas Anthony

    IPC: G01N21/65 ,  G01J3/44 ,  G01J3/28

    CPC classification number: G01N21/65 ,  G01J3/0208 ,  G01J3/0237 ,  G01J3/0248 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/44 ,  G01J2003/2826 ,  G01N2201/025 ,  G01N2201/06113 ,  G01N2201/103 ,  G01N2201/11 ,  G01N2201/117 ,  G01N2201/122

    Abstract: This invention concerns spectroscopy apparatus comprising a light source (101) arranged to generate a light profile (110) on a sample, a photodetector (103) having at least one photodetector element (104) for detecting characteristic light generated from interaction of the sample with light from the light source (101), a support (109) for supporting the sample, the support (109) movable relative to the light profile (110), and a processing unit (121). The processing unit (121) is arranged to associate a spectral value recorded by the photodetector element (104) at a particular time with a point on the sample predicted to have generated the characteristic light recorded by the photodetector element (104) at the particular time based on relative motion anticipated to have occurred between the support (109) and the light profile (110).

    Abstract translation: 本发明涉及光谱设备，其包括被布置成在样品上产生光谱（110）的光源（101），具有至少一个光电检测器元件（104）的光电检测器（103），用于检测由样品与 来自光源（101）的光，用于支撑样品的支撑件（109），可相对于光轮廓（110）移动的支撑件（109）和处理单元（121）。 处理单元（121）被布置为将由特定时间的光电检测器元件（104）记录的光谱值与预测在特定时间产生由光电检测器元件（104）记录的特征光的样品上的点相关联 基于预期在支撑件（109）和光轮廓（110）之间发生的相对运动。

    PROCESS AND APPARATUS FOR THE DETERMINATION OF ANALYTES IN LIQUID SAMPLES
    50.
    发明申请
    PROCESS AND APPARATUS FOR THE DETERMINATION OF ANALYTES IN LIQUID SAMPLES 审中-公开
    用于确定液体样品中分析物的方法和装置

    公开(公告)号：WO1993003345A1

    公开(公告)日：1993-02-18

    申请号：PCT/IT1992000093

    申请日：1992-08-05

    Applicant: MOSCETTA, Pompeo

    IPC: G01N01/00

    CPC classification number: G01N35/1097 ,  G01N35/08 ,  G01N2201/122 ,  Y10T436/11 ,  Y10T436/2575

    Abstract: An apparatus for the determination of analytes in liquid samples is disclosed. The apparatus comprises in fluid connection a positive-displacement pump (18), a chamber (16) in which the reagents specific for the analytes to be determined can be delivered, a detector (23), a second chamber (43) and a device (4) for the introduction of sample within the circuit and for the discharge. The apparatus also provides for controlling flow means and means (7) for the control of the operation of each component. A process for the determination of said analytes is also disclosed.

    Abstract translation: 公开了一种用于测定液体样品中分析物的装置。 该装置包括流体连接的容积式泵（18），其中特定于要确定的待分析物的试剂可以被输送的室（16），检测器（23），第二室（43）和装置 （4）用于在电路内引入样品并进行放电。 该装置还提供用于控制流量装置和装置（7），用于控制每个部件的操作。 还公开了用于确定所述分析物的方法。

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