公开(公告)号：WO1989011823A1

公开(公告)日：1989-12-14

申请号：PCT/US1989002505

申请日：1989-06-08

Applicant: VITAL SIGNALS, INC.

Inventor： VITAL SIGNALS, INC. ,  KORTEN, Jerome, B. ,  SCHULZE, Karl, F.

IPC: A61B05/08

CPC classification number: A61B5/087 ,  A61B5/7239 ,  G06F19/00 ,  G06F19/3481 ,  G16H40/63

Abstract: An apparatus and method are disclosed for monitoring physiological parameters associated with the ventilation of infants during assisted ventilation. The infant is placed in a plethysmograph and various sensor means are used to measure flow of gas into and out of the plethysmograph and infant respiration. The outputs of the sensor means are supplied to a microcomputer system for processing. A unique calibration system is provided which constantly corrects for changing system parameters such as plethysmographic chamber air leaks, compliance and the like. Additionally, a heating system which exhibits radiant as well as convective heating properties is provided to maintain the infant in a constant temperature environment with a minimal amount of temperature fluctuation. From this data, ventilator breaths are discriminated from infant breaths.

公开(公告)号：WO1985002104A1

公开(公告)日：1985-05-23

申请号：PCT/FR1984000258

申请日：1984-11-12

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE LOUIS PASTEUR (STRASBOURG I) ,  SPEICH, Jean-Pierre ,  ZOULOUMIAN, Pierre, Joseph

Inventor： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE LOUIS PASTEUR (STRASBOURG I)

IPC: A61B05/08

CPC classification number: A61M16/20 ,  A61B5/08 ,  A61B5/085 ,  A61M16/0858 ,  A61M2209/02

Abstract: A quick occlusion controlled device particularly intended to evaluate the sensitivity of respiratory centres comprises a body (1) connected to the respiratory apparatus of the patient through a buccal connector (2), provided with a pressure tap (3). According to the invention, the device is characterized in that the body (1) comprises an inspiration connector (4) which opens into the inner volume of the body (1) through a valve (5), as well as a respiration connector (6) which opens into the inner volume of the body (1) through a second valve (7), said device being further provided with an occlusion means of both/either of the valves (5) and (7).

Abstract translation: 特别旨在评估呼吸中枢的敏感性的快速阻塞控制装置包括通过设置有压力分接头（3）的颊部连接器（2）连接到患者的呼吸装置的主体（1）。 根据本发明，该装置的特征在于，主体（1）包括通过阀（5）向主体（1）的内部容积以及呼吸连接器（6）打开的吸气连接器（4） ），其通过第二阀（7）进入主体（1）的内部容积，所述装置还设置有两个/任一阀（5）和（7）的闭塞装置。

公开(公告)号：WO1984001704A1

公开(公告)日：1984-05-10

申请号：PCT/SE1983000370

申请日：1983-10-28

Applicant: KAROLINSKA INSTITUTET ,  LINNARSSON, Dag ,  RIBBE, Tommy ,  MATELL, Georg

Inventor： KAROLINSKA INSTITUTET

IPC: A61B05/08

CPC classification number: A61B5/087

Abstract: An arrangement for measuring bidirectional respiration flow, including a hose (1) which is connected to the breathing passages of a patient in which, via a Y-piece (2) is also connected to a tube (3) for inspiration gas and to a tube (4) for expiration gas. The tubes (3, 4) are connected to a breathing apparatus. Each tube has a venturi means arranged therein. According to the invention a pressure differential meter (8) having two inlets is connected with one inlet to each venturi means. A magnet valve (7) is arranged to periodically connect both inlets together, and there is provided an electronic means (9) for calculating the valve measured and for controlling the zero-setting, to which end the control means is connected electrically to the pressure differential meter (8) and to the magnet valve (7).

Abstract translation: 一种用于测量双向呼吸流量的装置，包括连接到患者的呼吸通道的软管（1），其中，通过Y型片（2）也连接到用于吸入气体的管（3）和 管（4）用于呼气。 管（3,4）连接到呼吸器。 每个管具有布置在其中的文丘里装置。 根据本发明，具有两个入口的压差计（8）与每个文氏管装置的一个入口连接。 电磁阀（7）被布置成周期性地将两个入口连接在一起，并且设置有用于计算所测量的阀并用于控制零点设置的电子装置（9），控制装置的哪一端电连接到压力 差速计（8）和磁阀（7）。

公开(公告)号：WO1981002512A1

公开(公告)日：1981-09-17

申请号：PCT/US1980000316

申请日：1980-03-10

Applicant: AMERICAN HOSPITAL SUPPLY CORP

Inventor： AMERICAN HOSPITAL SUPPLY CORP ,  ELINGS V ,  LEWIS F

IPC: A61B05/08

CPC classification number: A61B5/028

Abstract: Apparatus for providing a measure of extravascular lung water of a subject using a single thermal indicator, including means (16) for providing an injection of the thermal indicator into the bloodstream of the subject at a position proximal to or in the right heart (10) means (26) for detecting a first time-temperature concentration curve of the bloodstream at a position in the pulmonary artery, means (104) responsive to the first time-temperature concentration curve detected in the pulmonary artery for calculating a characteristic time for the first time-temperature concentration curve, means (28) for detecting a second time temperature concentration curve of the bloodstream at a position in a systemic artery, means (104) responsive to the second time-temperature concentration curve detected in the systemic artery for calculating a characteristic time for the second time-temperature concentration curve, means (104) for calculating the flow of blood through the heart and lungs, and means (104) for calculating a measure of extra-vascular lung water in accordance with the difference between the products of the blood flow times the first characteristic time and the blood flow times the second characteristic time.

Abstract translation: 用于使用单个热指示器提供受试者的血管外肺水的量度的装置，包括用于在靠近或右心脏（10）的位置处提供热指示器注射到受试者血流中的装置（16） 用于检测在肺动脉位置处的血流的第一时间 - 温度浓度曲线的装置（26），响应于在肺动脉中检测到的第一时间 - 温度浓度曲线来计算第一个 时间 - 温度浓度曲线，用于检测全身动脉位置处的血流的第二时间温度浓度曲线的装置（28），响应于在全身动脉中检测到的第二时间 - 温度浓度曲线计算 第二时间 - 温度浓度曲线的特征时间，用于计算通过心脏和肺的血流量的手段（104），以及 ns（104），用于根据血流量与第一特征时间之间的差异与血液流过第二特征时间计算血管外肺水的量度。

公开(公告)号：WO2005072618A1

公开(公告)日：2005-08-11

申请号：PCT/US2005/003398

申请日：2005-01-28

Applicant: EVEREST BIOMEDICAL INTRUMENTS CO. ,  JANSKI, Alvin ,  MARTINOSKY, Joe

Inventor： JANSKI, Alvin ,  MARTINOSKY, Joe

IPC: A61B05/08

CPC classification number: A61B5/4824 ,  A61B5/083 ,  A61B5/7275 ,  G06F19/00

Abstract: A method for predicting the onset of any (NO)-related negative influence of hemolysis, such as pain or the likely occurrence of a troske, in a human patient by detecting abnormal levels of hemolysis, through the measurement of one or more breath gas concentrations.

Abstract translation: 通过测量一种或多种呼吸气体浓度来预测人类患者中任何（NO）相关的溶血的负面影响（例如疼痛或可能发生的风疹）的发生的方法，通过检测异常的溶血水平 。

公开(公告)号：WO1997037591A1

公开(公告)日：1997-10-16

申请号：PCT/SG1997000013

申请日：1997-04-07

Applicant: RHEO-GRAPHIC PTE LTD ,  SCHOOKIN, Sergei, I. ,  ZUBENKO, Viatcheslav G. ,  BELIAEV, Konstantin R. ,  MOROZOV, Aleksandr A. ,  YONG, Wen, H.

Inventor： RHEO-GRAPHIC PTE LTD

IPC: A61B05/08

CPC classification number: A61B5/0809 ,  A61B5/0535 ,  A61B5/7239 ,  A61B5/7257

Abstract: A method and apparatus for determination of heart rate, heart stroke volume, and cardiac output from thoracic bioimpedance signals and electrocardiograms. A unique bioimpedance electrode arrangement is employed, and the bioimpedance signals are corrected for gain phase-frequency distortion through the use of sinusoidal test signals through the measuring or detection electrodes to identify distortions and correct for same during actual measurements. Time-derivative bioimpedance signals are employed, the power spectrum calculated, and a novel autoconvolution procedure used to emphasize the heart rate harmonic. Breath waves and other signals not indicative of the patient's cardiocycles are removed. Left ventricular ejection time is derived from the bioimpedance signals, and an improved version of Kubicek's equation is employed to derive heart stroke volume and thus cardiac output.

Abstract translation: 用于确定胸部生物阻抗信号和心电图的心率，心脏搏动量和心输出量的方法和装置。 采用独特的生物阻抗电极布置，并且通过使用正弦测试信号通过测量或检测电极来校正生物阻抗信号以获得增益相位频率失真，以在实际测量期间识别失真并对其进行校正。 采用时间导数生物阻抗信号，计算功率谱，并采用一种用于强调心率谐波的新型自动卷积程序。 呼吸波和其他不能指示患者心脏的信号被去除。 左心室射血时间来自生物阻抗信号，采用Kubicek方程的改进版本来导出心脏搏动量，从而导致心输出量。

公开(公告)号：WO1997025920A1

公开(公告)日：1997-07-24

申请号：PCT/IB1997000012

申请日：1997-01-13

Applicant: BIOMEDIN ,  TORRESIN, Giuseppe

Inventor： BIOMEDIN

IPC: A61B05/08

CPC classification number: G01F1/6986 ,  A61B5/0878 ,  G01F1/692

Abstract: It is disclosed a device based on active element(s) (1, 25) that can both monitor/measure and control the temperature of a given environment. Such element(s) are characterized by a low thermal capacity and are supplied power by means of a pulse width modulating technique. Monitoring is performed - on the same element(s) - by means of analysis of the temperature relaxation between heating pulses. The element(s) can be controlled to body temperature, thus resulting in a low-power, high-precision, pocket-size and light-weight instrument (pneumotacograph) suitable to perform accurate spirometry measurements. The device can be easily adapted for applications in high precision flow rate measurements and high sensitivity calorimetry as well.

Abstract translation: 公开了一种基于有源元件（1,25）的装置，其可以监测/测量和控制给定环境的温度。 这种元件的特征在于低热容量，并且通过脉冲宽度调制技术供电。 通过分析加热脉冲之间的温度弛豫，在相同的元件上进行监控。 可以将元件控制到体温，从而产生适于执行精确肺量计测量的低功率，高精度，口袋尺寸和重量轻的仪器（aerotacograph）。 该装置可以轻松适应高精度流量测量和高灵敏度量热法的应用。

公开(公告)号：WO1996019142A1

公开(公告)日：1996-06-27

申请号：PCT/US1995016735

申请日：1995-12-19

Applicant: SNAP LABORATORIES L.L.C.

Inventor： SNAP LABORATORIES L.L.C. ,  RAVIV, Gil ,  WEINGARTEN, Charles, Z.

IPC: A61B05/08

CPC classification number: A61B7/003

Abstract: The invention provides a method of classifying respiratory sounds. The method provides the steps of selecting a first set of respiratory sounds (102) and manually determining a classification content of the first set of respiratory events. The method further includes extrapolating the classification content (109) of the first set of respiratory events (110) to an at least second set of respiratory events (111).

Abstract translation: 本发明提供了一种分类呼吸音的方法。 该方法提供了选择第一组呼吸音（102）并手动确定第一组呼吸事件的分类内容的步骤。 该方法还包括将第一组呼吸事件（110）的分类内容（109）外推到至少第二组呼吸事件（111）。

公开(公告)号：WO1996003074A1

公开(公告)日：1996-02-08

申请号：PCT/US1995009363

申请日：1995-07-24

Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA ,  WILSON, David, F. ,  PAWLOWSKI, Marek

Inventor： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

IPC: A61B05/08

CPC classification number: A61B5/14556 ,  A61B5/0059 ,  A61B5/14552 ,  A61B5/1491 ,  A61B5/6833 ,  A61B2562/146 ,  G01N21/6408 ,  G01N21/6456 ,  G01N21/6458 ,  G01N21/6486 ,  Y10T436/20

Abstract: Apparatus and method for measuring tissue oxygenation using oxygen dependent quenching phosphorescence. The apparatus (10) comprises a phosphorescent probe (14) applied to the surface of the skin (15); an oxygen impermeable film (16) placed over the probe (14) and the apparatus (10); a light excitation means (12) for exciting the probe (14); a heating element (22) for heating the probe (14); and an analyzer circuit (26) for analyzing the output.

Abstract translation: 使用氧依赖性猝灭磷光测量组织氧合的装置和方法。 装置（10）包括施加到皮肤表面（15）的磷光探针（14）。 放置在探针（14）和装置（10）上方的不透氧薄膜（16）; 用于激发探头（14）的光激励装置（12）; 用于加热探针（14）的加热元件（22）。 以及用于分析输出的分析器电路（26）。

公开(公告)号：WO1995005119A2

公开(公告)日：1995-02-23

申请号：PCT/US1994009004

申请日：1994-08-11

Applicant: STEPHENS, David, L.

IPC: A61B05/08

CPC classification number: A61B5/6805 ,  A61B5/1135

Abstract: A breathing monitor article of wearing apparel, adapted for child users in order to monitor breathing conditions of a child user. The apparatus and the method of the invention are particularly adaptable for infant child users in order to prevent conditions such as Sudden Infant Death Syndrom and similar conditions arising from apnea. The article of wearing apparel comprises a shirt or like garment adapted to extend around the chest and/or abdomen portion of the child user and which contains a pocket having a monitor therein. An elastic belt extends about the chest and/or abdomen of the user and, particularly, in the region of the user's lungs. A strain gauge is secured to the elastic belt and detects breathing movement through the expansion and contraction of the chest wall. The monitor is electronically operated and constructed so as to generate an alarm signal if there is a cessation of breathing for a minimum predetermined time period. The shirt, or like garment, is also constructed so that when it is secured to the child user, it automatically energizes the monitor, thereby eliminating the necessity of an attendant to the child from turning the monitor on or off.

Abstract translation: 一种适合儿童使用者的呼吸监护仪，用于监测儿童使用者的呼吸状况。 本发明的装置和方法特别适用于婴儿儿童用户，以防止诸如突发性婴儿死亡综合症等症状以及由呼吸暂停引起的类似病症。 穿着物品包括适于在儿童使用者的胸部和/或腹部部分周围延伸并且包含其中具有监视器的口袋的衬衫或类似服装。 弹性带围绕使用者的胸部和/或腹部延伸，并且特别是在使用者的肺部的区域中延伸。 应变计固定在弹性带上，并通过胸壁的膨胀和收缩来检测呼吸运动。 监视器是电子操作和构造的，以便在最短预定时间段内停止呼吸时产生报警信号。 衬衫或类似的衣服也被构造成使得当它被固定到儿童使用者时，它自动激励监视器，从而消除了对孩子的服务员不必打开或关闭监视器的需要。