公开(公告)号：EP0843735B2

公开(公告)日：2006-12-27

申请号：EP95942776.6

申请日：1995-12-21

Applicant: Forfas (trading as Bioresearch Ireland) ,  University College Cork-National University of Ireland, Cork

Inventor： McCARTHY, Thomas, Valentine ,  VAUGHAN, Patrick, Martin

IPC: C12Q1/68

CPC classification number: C12Q1/6834 ,  C12Q1/6827 ,  C12Q1/6853 ,  C12Q1/689 ,  C12Q2600/156

Abstract: A method for rapidly detecting the presence or absence of a particular nucleic acid sequence at a candidate locus in a target nucleic acid sample comprises the steps of: i) introducing a modified base which is a substrate for a DNA glycosylase into said candidate locus at one or more preselected positions; ii) excising the modified base by means of said DNA glycosylase so as to generate an abasic site; iii) cleaving phosphate linkages at abasic sites generated in step ii); and iv) analysing the cleavage products of step iii) so as to identify in said target nucleic acid sequence the presence or absence of said particular nucleic acid sequence at said candidate locus. The method has particular application for detecting specific mutations in a DNA sample, including the detection of multiple known mutations in DNA. Large throughput of sample can be achieved rapidly and easily.

公开(公告)号：EP1058092A3

公开(公告)日：2005-01-19

申请号：EP00650057.3

申请日：2000-05-24

Applicant: FORFAS, (trading as PEI Technologies)

Inventor： Leahy, Martin J. ,  Byrne, Catherine ,  Clothier, Stephen ,  O'Regan, Gerard ,  Samways, Philip ,  Punch, Jeffrey ,  Davies, Mark

IPC: G01D3/08 ,  G01D1/00

CPC classification number: G01D3/08

Abstract: A data capture system (1) has modular amplifier circuits (10) connected to modular capture circuits (11) within a rotor 2. Each capture circuit (11) has an FPGA (26) operation according to low-frequency and high-frequency state machines (M1, M2) to control ADCs (25) and upload from memories (30) to a host (15). During sampling, each FPGA (26) runs through a ready mode, a sampling mode, and again a ready mode according to a host command.

公开(公告)号：EP1164689A3

公开(公告)日：2003-09-10

申请号：EP01650072.0

申请日：2001-06-13

Applicant: FORFAS, (trading as PEI Technologies)

Inventor： O'Sullivan, Dara, Pei Technologies ,  Egan, Michael, Pei Technologies ,  Willers, Michael, Pei Technologies

IPC: H02M1/00 ,  H02M7/155

CPC classification number: H02M1/4258 ,  Y02B70/126

Abstract: An ac/dc converter (1) has a closed loop controller (3) to maintain a well regulated output voltage (V o ) with low peak-to-peak ripple. A resonant capacitor ( C in ) across the rectifier bridge ( D R1 -D R4 ), and a resonant inductor ( L R ) between the bridge and the isolation transformer provide inherent power factor correction. A clamping diode ( D CL ) is connected between the dc rectifier bridge positive terminal and the bulk capacitor ( C B ). There is also a second resonant capacitor ( C t ) across the isolation transformer. There is zero voltage switching of the power switches ( Q1 , Q2 ).

公开(公告)号：EP0466428A2

公开(公告)日：1992-01-15

申请号：EP91306167.7

申请日：1991-07-08

Applicant: FORFAS

Inventor： Reinhardt, Robert Christopher ,  Humphreys, Richard Macartan

IPC: F25C5/00 ,  B65G53/06

CPC classification number: B65G53/60 ,  B65G53/06 ,  B65G53/525 ,  F25C5/20

Abstract: In apparatus for conveying batches of ice lumps from a storage hopper (2) to remotely located ice dispensers (7), ice lumps from the storage hopper (2) are delivered into the main conduits (5) through corresponding main valves (20) and connecting conduits (25) extending between each main valve (20) and the storage hopper (2). Metering valves (14) meter batches of ice lumps of predetermined size into the main conduits (5). Conveying air from an air blower (10) is supplied to the main conduits (5) through the main valves (20) for conveying the batches of ice lumps. In use, batches of ice lumps are intermittently delivered into the main conduit (5), and the batches of ice lumps and conveying air are alternately supplied to the main conduit (5).

Abstract translation: 在用于将存储料斗（2）中的批块冰块输送到位于远处的分配器（7）的设备中，来自储存料斗（2）的冰块通过相应的主阀（20）和 在每个主阀（20）和存储料斗（2）之间延伸的连接管道（25）。 计量阀（14）将预定尺寸的冰块的批量计量到主管道（5）中。 通过主阀（20）将从空气鼓风机（10）输送的空气供给到主管道（5），以输送多个冰块。 在使用中，批量的冰块被间歇地输送到主管道（5）中，并且批量的冰块和输送空气交替地供应到主管道（5）。

公开(公告)号：DE69527444T3

公开(公告)日：2007-08-16

申请号：DE69527444

申请日：1995-12-21

Applicant: FORFAS TRADING AS BIORES IRELA ,  UNIV COLLEGE CORK NAT UNIV IE

Inventor： MCCARTHY VALENTINE ,  VAUGHAN MARTIN

IPC: C12N15/09 ,  C12Q1/68 ,  C12Q1/6827 ,  C12Q1/6834 ,  C12Q1/6853 ,  C12Q1/689

公开(公告)号：ES2176358T3

公开(公告)日：2002-12-01

申请号：ES95942776

申请日：1995-12-21

Applicant: FORFAS TRADING AS BIORES IRELA ,  UNIV COLLEGE CORK NAT UNIV IE

Inventor： MCCARTHY THOMAS VALENTINE ,  VAUGHAN PATRICK MARTIN

IPC: C12N15/09 ,  C12Q1/68 ,  C12Q1/6827 ,  C12Q1/6834 ,  C12Q1/6853 ,  C12Q1/689

公开(公告)号：DE69527444D1

公开(公告)日：2002-08-22

申请号：DE69527444

申请日：1995-12-21

Applicant: FORFAS TRADING AS BIORES IRELA ,  UNIV COLLEGE CORK NAT UNIV IE

Inventor： MCCARTHY VALENTINE ,  VAUGHAN MARTIN

IPC: C12N15/09 ,  C12Q1/68 ,  C12Q1/6827 ,  C12Q1/6834 ,  C12Q1/6853 ,  C12Q1/689

公开(公告)号：DE69126247T2

公开(公告)日：1998-01-08

申请号：DE69126247

申请日：1991-07-08

Applicant: FORFAS

Inventor： REINHARDT ROBERT CHRISTOPHER ,  HUMPHREYS RICHARD MACARTAN

IPC: B65G53/06 ,  F25C5/00

Abstract: In apparatus for conveying batches of ice lumps from a storage hopper (2) to remotely located ice dispensers (7), ice lumps from the storage hopper (2) are delivered into the main conduits (5) through corresponding main valves (20) and connecting conduits (25) extending between each main valve (20) and the storage hopper (2). Metering valves (14) meter batches of ice lumps of predetermined size into the main conduits (5). Conveying air from an air blower (10) is supplied to the main conduits (5) through the main valves (20) for conveying the batches of ice lumps. In use, batches of ice lumps are intermittently delivered into the main conduit (5), and the batches of ice lumps and conveying air are alternately supplied to the main conduit (5).

公开(公告)号：AU2305397A

公开(公告)日：1997-10-10

申请号：AU2305397

申请日：1997-03-19

Applicant: FORFAS

Inventor： MURRAY CHRISTOPHER PATRICK ,  O'MATHUNA SEAN CIAN

IPC: H01F41/16 ,  H01F41/02

公开(公告)号：IE970237A1

公开(公告)日：1997-10-08

申请号：IE970237

申请日：1997-03-27

Applicant: FORFAS

Inventor： DAVIES MARK

IPC: G01P3/36 ,  H02K11/00

Abstract: An optical slip ring system (1) has rotor interface (2) which can bolt on to a high speed rotor in a modular manner. The rotor interface (2) has circular circuit boards (7) containing the necessary drive circuits and power supply circuits for transducers mounted on the rotor. The drive circuit on the boards (7) drive three rings of emitter LEDs (9). The drive is frequency modulated and there are a number of transducers associated with each ring of emitter LEDs (9). These signals are frequency division multiplexed to ensure real time processing takes place. A fixed support (3) has a single receiver LED (15) associated with each ring of emitter LEDs (9). Contactless power is provided by an inductive power supply having a primary winding (16) on the fixed support bracket (3) and a secondary winding (10) on the rotor interface (2). .