公开(公告)号：WO2011043519A2

公开(公告)日：2011-04-14

申请号：PCT/KR2010/001633

申请日：2010-03-17

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  PAE, Ae Nim ,  CHOO, Hyunah ,  CHO, Yong Seo ,  JUN, Sun Ah ,  CHO, Hye Jin ,  PARK, Woo Kyu ,  KIM, Jeong Min

Inventor： PAE, Ae Nim ,  CHOO, Hyunah ,  CHO, Yong Seo ,  JUN, Sun Ah ,  CHO, Hye Jin ,  PARK, Woo Kyu ,  KIM, Jeong Min

IPC: C07C311/16

CPC classification number: C07C311/18 ,  C07C2601/08 ,  C07D207/09 ,  C07D207/14 ,  C07D211/14 ,  C07D295/13 ,  C07D409/12

Abstract: The present invention relates to sulfonamide derivatives as a serotonin receptor antagonist and serotonin reuptake inhibitor and a pharmaceutically acceptable salt thereof. The sulfonamide derivatives have serotonin 5-HT 2A and 5-HT 2C receptor antagonizing and serotonin reuptake inhibiting functions, and thus may be efficiently applied to a CNS-related disease such as depression, obesity, psychosis, schizophrenia, suicidal tendency, anxiety, obsessional neurosis, migraine, appetite disorders, sleep disorders, stroke, and withdrawal symptoms caused by drug abuse.

Abstract translation: 本发明涉及作为血清素受体拮抗剂和血清素再摄取抑制剂的磺酰胺衍生物及其药学上可接受的盐。 磺酰胺衍生物具有血清素5-HT 2A和5-HT 2C受体拮抗作用和5-羟色胺再摄取抑制功能，因此可以有效地应用于CNS相关疾病，例如 抑郁症，肥胖症，精神病，精神分裂症，自杀倾向，焦虑症，强迫症，偏头痛，食欲不振，睡眠障碍，中风和药物滥用引起的戒断症状。

公开(公告)号：WO2011025230A9

公开(公告)日：2011-03-03

申请号：PCT/KR2010/005653

申请日：2010-08-24

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Changjoon Justin ,  LEE, Soo-Jung ,  YOON, Bo-Eun

Inventor： LEE, Changjoon Justin ,  LEE, Soo-Jung ,  YOON, Bo-Eun

IPC: A61K31/465 ,  A61K31/7105 ,  A61P25/08 ,  A61P25/28

Abstract: A GABA (gamma-aminobutyric acid) release-inhibiting agent in the cerebellum and a composition for treating pathological symptoms caused by over-release of GABA in the cerebellum, each comprising a Bestrophin 1(Best1) channel inhibitor as an active ingredient; a GABA release-promoting agent in the cerebellum and a composition for treating pathological symptoms caused by the deficit of GABA in the cerebellum, each comprising a Best1 channel activator as an active ingredient; and a method for screening a GABA release-regulating agent in the cerebellum, which uses Best1 channel as target, are provided.

公开(公告)号：WO2010104249A1

公开(公告)日：2010-09-16

申请号：PCT/KR2009/004510

申请日：2009-08-12

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  WOO, Deok Ha ,  KIM, Sun Ho ,  LEE, Seok ,  BYUN, Young Tae ,  JHON, Young Min

Inventor： WOO, Deok Ha ,  KIM, Sun Ho ,  LEE, Seok ,  BYUN, Young Tae ,  JHON, Young Min

IPC: H01L33/12

CPC classification number: H01L33/0079

Abstract: Embodiments of a method for forming a light emitting device are disclosed. This method includes forming a stacked structure including a substrate, a lower semiconductor layer of a first conductivity type, an active layer, and an upper semiconductor layer of a second conductivity type, wherein the stacked structure includes a separation layer formed below the active layer by ion implantation, and performing a thermal process upon the stacked structure to divide the separation layer laterally such that the stacked structure is separated into an upper part and a lower part. The light emitting device may be fabricated with substrate separation by ion implantation to prevent cracking and enable fabrication of a large size light emitting device having high efficiency at low costs.

Abstract translation: 公开了一种用于形成发光器件的方法的实施例。 该方法包括形成包括基板，第一导电类型的下半导体层，有源层和第二导电类型的上半导体层的堆叠结构，其中堆叠结构包括通过在有源层下方形成的分离层 离子注入，并且在堆叠结构上进行热处理以横向划分分离层，使得层叠结构被分离成上部和下部。 发光器件可以通过离子注入的衬底分离来制造，以防止破裂，并且能够以低成本制造高效率的大尺寸发光器件。

公开(公告)号：WO2010041794A1

公开(公告)日：2010-04-15

申请号：PCT/KR2008/007671

申请日：2008-12-24

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  CHOI, Ji Hyun ,  SHIN, Hee Sup ,  KOCH, Klaus Peter

Inventor： CHOI, Ji Hyun ,  SHIN, Hee Sup ,  KOCH, Klaus Peter

IPC: A61B5/0478

CPC classification number: A61B5/0478 ,  A61B5/4094 ,  A61B2503/40 ,  A61B2562/0209 ,  A61B2562/046

Abstract: Disclosed are a novel, elastic, biocompatible, micro-sized, polyimide- based multi-channel microelectrode for recording of electroencephalography (EEG) from a laboratory animal including mouse, and a method for recording of laboratory animal EEG using the microelectrode. The microelectrode may include 2 grounding electrodes and 32 recording electrodes. A connector for signal transmission easily connects the microelectrode to a signal acquiring apparatus. The total weight of the microelectrode, including the connector, does not exceed 150 mg. Laboratory animal EEG, including that of mouse, provides the advantage of monitoring the brain state of a freely moving animal following a genetic or pharmaceutical manipulation. The microelectrode can be implanted without surgery and may be detached from wires while EEG is not recorded from the laboratory animal. The microelectrode can successfully acquire broadband EEG signals from the skull of the laboratory animal and is effective in monitoring spatial and temporal pattern of brain activities of the laboratory animal.

Abstract translation: 公开了一种用于从包括小鼠的实验室动物记录脑电图（EEG）的新型，弹性的，生物相容的，微尺寸的基于聚酰亚胺的多通道微电极，以及使用微电极记录实验动物脑电图的方法。 微电极可以包括2个接地电极和32个记录电极。 用于信号传输的连接器容易地将微电极连接到信号获取装置。 包括连接器在内的微电极的总重量不超过150mg。 包括小鼠在内的实验动物脑电图提供了在遗传或药物操作后监测自由移动的动物的脑状态的优点。 微电极可以手术植入，并且可能从电线脱离，而EEG未从实验室动物记录。 微电极可以从实验动物头骨中成功获取宽带脑电信号，有效监测实验动物脑部活动的时空格局。

公开(公告)号：WO2009157730A2

公开(公告)日：2009-12-30

申请号：PCT/KR2009/003450

申请日：2009-06-25

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Hyung Lae ,  PARK, Ji Hyung ,  JEONG, Hee Seok ,  YEOM, Ki Woon ,  LEE, Joong-Ho ,  SHIN, Hyun-jin

Inventor： LEE, Hyung Lae ,  PARK, Ji Hyung ,  JEONG, Hee Seok ,  YEOM, Ki Woon ,  LEE, Joong-Ho ,  SHIN, Hyun-jin

IPC: G06F3/01 ,  G06F3/03 ,  G06F15/00

CPC classification number: G06F3/017 ,  G06F19/00

Abstract: The disclosure relates to a system for controlling devices and information on a network by hand gestures, and more particularly, to a system for controlling devices and information on a network by hand gestures in which a device or a file to be controlled is selected by a user and a display device is pointed so that information and data can be shared and that various devices can be coupled to each other easily and can be controlled easily. The system for controlling devices and information on a network by hand gestures can remarkably improve the interaction between various input and display devices and a user under a ubiquitous computing environment.

Abstract translation: 本公开涉及一种用于通过手势来控制网络上的设备和信息的系统，更具体地，涉及一种用于通过手动手势来控制设备和网络上的信息的系统，其中要控制的设备或文件被 用户和显示设备被指向，使得可以共享信息和数据，并且可以容易地将各种设备彼此耦合并且可以容易地被控制。 通过手势控制网络上的设备和信息的系统可以显着提高各种输入和显示设备与无处不在的计算环境下的用户之间的交互。

公开(公告)号：WO2009096612A1

公开(公告)日：2009-08-06

申请号：PCT/KR2008/000564

申请日：2008-01-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Changjoon Justin ,  WOO, Dong-Ho ,  PARK, Hyung-Ju

Inventor： LEE, Changjoon Justin ,  WOO, Dong-Ho ,  PARK, Hyung-Ju

IPC: A61K48/00 ,  C12N15/11

CPC classification number: C12N15/1138 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53

Abstract: A novel use of anion channels, preferably Ca 2+ -activated anion channels (CAACs), in regulating release of neurotransmitters from neurons and/or astrocytes is provided. More specifically, CAAC activity regulators, agents for regulating neurotransmitter release comprising such CAAC activity regulators, and methods of screening agents for regulating neurotransmitter release using CAAC as a target.

Abstract translation: 提供阴离子通道，优选Ca2 +活化阴离子通道（CAAC）在调节神经元和/或星形胶质细胞释放神经递质中的新用途。 更具体地，CAAC活性调节剂，用于调节包含这种CAAC活性调节剂的神经递质释放剂，以及使用CAAC作为靶标调节神经递质释放调节剂的方法。

公开(公告)号：WO2009054701A2

公开(公告)日：2009-04-30

申请号：PCT/KR2008/006305

申请日：2008-10-24

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KIM, Su-Nam ,  UM, Byung Hun ,  KIM, Chul Young ,  LEE, Woo Jung ,  PARK, Yeon-Suk ,  KANG, Suk Woo

Inventor： KIM, Su-Nam ,  UM, Byung Hun ,  KIM, Chul Young ,  LEE, Woo Jung ,  PARK, Yeon-Suk ,  KANG, Suk Woo

IPC: A61K36/185

CPC classification number: A61K36/45 ,  A23L2/02 ,  A23L2/52 ,  A23L33/105 ,  A61K8/97 ,  A61K9/0095 ,  A61K9/1617 ,  A61K9/1623 ,  A61K9/2018 ,  A61K9/2059 ,  A61K2800/522 ,  A61K2800/782 ,  A61Q19/08

Abstract: The present invention relates to a composition containing Ortilia secunda extract as an active ingredient. Ortilia secunda extract of the present invention extracted by using water, alcohol or a mixture thereof as a solvent inhibits the activity of AP-I (activator protein-1), a MMP-I transcription factor, inhibits type I collagenase, a skin matrix decomposing enzyme, but increases collagen, a major component of skin, so that it can be effectively used as a preparation for skin external application including cosmetics owing to its wrinkle and elasticity improving effects. In addition, Ortilia secunda extract of the present invention has radial scavenging effect, so that it can also be effectively used as an antioxidative agent.

Abstract translation: 本发明涉及含有Ortilia secunda提取物作为活性成分的组合物。 通过使用水，醇或其混合物作为溶剂提取的本发明的Ortilia secunda提取物抑制MMP-1转录因子AP-1（激活蛋白-1）的活性，抑制I型胶原酶，皮肤基质分解 但增加了作为皮肤主要成分的胶原蛋白，由于其皱纹和弹性改善效果，它可以有效地用作包括化妆品在内的皮肤外用制剂。 另外，本发明的Ortilia secunda提取物具有径向清除作用，因此它也可以有效地用作抗氧化剂。

公开(公告)号：WO2009054560A1

公开(公告)日：2009-04-30

申请号：PCT/KR2007/005415

申请日：2007-10-31

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  PARK, Dong Jin ,  LEE, Yong Bok ,  KIM, Chang Ho

Inventor： PARK, Dong Jin ,  LEE, Yong Bok ,  KIM, Chang Ho

IPC: F16C33/78

CPC classification number: F16C17/024 ,  F16C33/74 ,  F16C2360/23

Abstract: A bearing seal for a gas turbine for reducing axial leakage of a working gas of a turbine and for supporting the vertical loads and shear forces efficiently. The seal is disposed on an inner surface of a bearing housing where a rotating shaft is positioned at the center of the bearing housing. The bearing seal includes an elastic porous foil for adjusting leakage of a working gas through the space between the rotating shaft and the bearing housing, wherein a density ratio of the porous foil increases along gas inflow direction. The porous foil is deformed elastically by a dynamic pressure of the working gas leaked around the rotating shaft during rotation of the rotating shaft for making a gap between the porous foil and the rotating shaft.

Abstract translation: 用于燃气轮机的轴承密封件，用于减少涡轮机的工作气体的轴向泄漏并有效地支撑垂直载荷和剪切力。 密封件设置在轴承壳体的内表面上，其中旋转轴定位在轴承壳体的中心。 轴承密封件包括用于调节工作气体通过旋转轴和轴承壳体之间的空间的泄漏的弹性多孔箔，其中多孔箔的密度比沿气体流入方向增加。 在旋转轴旋转期间，在多孔箔与旋转轴之间形成间隙时，多孔箔在旋转轴周围泄漏的工作气体的动态压力变形。

公开(公告)号：WO2009020357A1

公开(公告)日：2009-02-12

申请号：PCT/KR2008/004589

申请日：2008-08-07

Applicant: SODIFF ADVANCED MATERIALS CO., LTD. ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  CHO, Byung Won ,  LEE, Joong Kee ,  LEE, Kyeong Jik ,  CHOI, Hyun Ki

Inventor： CHO, Byung Won ,  LEE, Joong Kee ,  LEE, Kyeong Jik ,  CHOI, Hyun Ki

IPC: H01M4/58

CPC classification number: H01M10/052 ,  H01M4/587 ,  H01M10/0525 ,  H01M2004/021 ,  H01M2004/027

Abstract: An anode active material for a lithium secondary cell comprising a carbon material which is surface-treated with He, N 2 , CO 2 , O 2 , F 2 , NF 3 or a mixture thereof has a good wetting property for both a water-based binder and a non-aqueous electrolyte, and makes a thin and stable SEI to be formed on its surface, thereby improves the energy density, the reversible capacity and the durability of a lithium secondary cell.

Abstract translation: 用于锂二次电池的负极活性材料包括用He，N 2，CO 2，O 2，F 2，NF 3或其混合物进行表面处理的碳材料，对水性粘合剂和非水性粘合剂都具有良好的润湿性， 并且在其表面上形成薄而稳定的SEI，从而提高锂二次电池的能量密度，可逆容量和耐久性。

公开(公告)号：WO2008136622A1

公开(公告)日：2008-11-13

申请号：PCT/KR2008/002515

申请日：2008-05-02

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KIM, Il-Doo ,  HONG, Jae-Min ,  JO, Seong-Mu

Inventor： KIM, Il-Doo ,  HONG, Jae-Min ,  JO, Seong-Mu

IPC: H01M4/02

CPC classification number: H01M4/131 ,  B82Y30/00 ,  C04B35/62231 ,  C04B35/6225 ,  C04B35/62254 ,  C04B35/62259 ,  C04B35/624 ,  C04B35/63416 ,  C04B2235/3232 ,  C04B2235/3256 ,  C04B2235/3258 ,  C04B2235/3272 ,  C04B2235/3275 ,  C04B2235/3277 ,  C04B2235/3279 ,  C04B2235/3281 ,  C04B2235/3284 ,  C04B2235/3286 ,  C04B2235/3293 ,  C04B2235/441 ,  C04B2235/444 ,  C04B2235/449 ,  C04B2235/526 ,  C04B2235/5264 ,  C04B2235/5454 ,  D01D5/0007 ,  D01F9/10 ,  H01M4/0435 ,  H01M4/0471 ,  H01M4/1391 ,  H01M4/661 ,  H01M10/052 ,  H01M2004/027 ,  Y10S977/948

Abstract: There is provided a metal oxide having a continuous nano-fiber network structure as a negative active material for a secondary battery. A method for fabricating such negative active material for a secondary battery comprises spinning a mixed solution of a metal oxide precursor and a polymer onto a collector to form composite fibers mixed with the metal oxide precursor and the polymer, thermally compressing or thermally pressurizing the composite fibers, and thermally treating the thermally compressed or thermally pressurized composite fibers to remove the polymer from the composite fiber.

Abstract translation: 提供具有连续纳米纤维网络结构的金属氧化物作为二次电池的负极活性材料。 制造这种二次电池用负极活性物质的方法包括将金属氧化物前体和聚合物的混合溶液旋转到集电体上，以形成与金属氧化物前体和聚合物混合的复合纤维，热压缩或热加压复合纤维 并且热处理热压缩或热加压复合纤维以从复合纤维中除去聚合物。