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公开(公告)号：US20150318661A1
公开(公告)日：2015-11-05
申请号：US14441029
申请日：2013-10-31
Applicant: FUJIKURA LTD. , NIPPON TELEGRAPH AND TELEPHONE CORPORATION , OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION , NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY
Inventor： Shoichiro Matsuo , Katsuhiro Takenaga , Kentaro Ichii , Hirotaka Ono , Kyouzou Tsujikawa , Makoto Yamada , Hiroji Masuda
CPC classification number: H01S3/06754 , G02B6/02042 , G02B6/03605 , G02B6/03611 , H01S3/06729 , H01S3/06733 , H01S3/06737 , H01S3/091 , H01S3/094007 , H01S3/2383
Abstract: The first cladding 52 has a two-layer structure formed of a solid inner layer 62A passed through the center axis of the first cladding 52 and an outer layer 62B enclosing the inner layer 62A and the plurality of cores 51 with no gap. A refractive index n1 of the core 51 is provided higher than refractive indexes n2A and n2B of the inner layer 62A and the outer layer 62B, the refractive indexes n2A and n2B of the inner layer 62A and the outer layer 62B are provided higher than a refractive index n3 of the second cladding 53, and the refractive index n2A of the inner layer 62A is provided lower than the refractive index n2B of the outer layer 62B.
Abstract translation: 第一包层52具有由穿过第一包层52的中心轴线的实心内层62A和不间隙地包围内层62A和多个芯51的外层62B形成的两层结构。 芯体51的折射率n1比内层62A和外层62B的折射率n2A，n2B高，内层62A和外层62B的折射率n2A，n2B高于屈光度 第二包层53的折射率n3和内层62A的折射率n2A被设定为低于外层62B的折射率n2B。
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52.发明申请METHOD FOR METAL CONCENTRATION, METHOD FOR METAL RECOVERY, DEVICE FOR METAL CONCENTRATION, AND DEVICE FOR METAL RECOVERY 审中-公开用于金属浓度的方法，用于金属回收的方法，用于金属浓度的装置和用于金属回收的装置公开(公告)号：US20150315670A1
公开(公告)日：2015-11-05
申请号：US14651065
申请日：2014-01-21
Inventor： Yasuhiro KONISHI , Norizoh SAITOH , Takanori AMBO , Kaoru TERAZAWA , Koichiro RYUNO , Yasuhiro NINOMIYA
CPC classification number: C12P3/00 , B22F9/24 , B22F2301/25 , B22F2301/255 , B22F2304/058 , C02F3/00 , C02F3/006 , C02F3/1268 , C02F3/346 , C02F2101/20 , C02F2101/203 , C02F2305/06 , C22B3/18 , C22B3/22 , C22B11/04 , Y02P10/234 , Y02P20/582 , Y02W10/15
Abstract: An objective of invention is conveniently concentrating a metal in a metal ion-containing solution with high efficiency and to recover the metal from the metal ion-containing solution with high recovery efficiency. A method for concentrating or recovering a metal in a metal ion-containing solution in the present invention is the method comprising the following steps, a reduction and accumulation step to reduce the metal ion into a metal fine particle and also to accumulate the metal fine particle in the microorganism by allowing the microorganism and an electron donor B to act on a metal ion-containing solution W0 and thus to obtain a solution W1 that contains a microorganism having a metal fine particle accumulated therein; a concentration step to concentrate the solution W1 that contains the microorganism having a metal fine particle accumulated therein by a filtration membrane and thus to obtain a concentrated solution W2; and a return step to return the concentrated solution W2 to first step above and thus to circulate. Further, A device for metal concentration or recovering in the present invention comprises the following: a storage unit 2 to store the solution W1, a concentration unit 3 to concentrate the solution W1 that is transferred from the storage unit 2 by a filtration membrane, and a return unit 4 to return a concentrated solution W2 that is concentrated in the concentration unit 3 to the storage unit 2.
Abstract translation: 本发明的目的是方便地将金属浓缩到含金属离子的溶液中，并以高回收率从含金属离子的溶液中回收金属。 本发明的金属离子含有溶液中的金属浓缩或回收方法是将金属离子还原成金属微粒并还能积聚金属微粒的还原积累步骤 在微生物中通过使微生物和电子给体B作用于含有金属离子的溶液W0，从而得到含有其中积聚有金属微粒的微生物的溶液W1; 浓缩步骤，将含有通过过滤膜积聚有金属微粒的微生物的溶液W1浓缩，得到浓缩液W2; 以及将浓缩溶液W2返回到上述第一步骤并由此循环的返回步骤。 此外，本发明的金属浓缩或回收装置包括：存储单元2，用于存储溶液W1;浓缩单元3，用于通过过滤膜将从存储单元2转移的溶液W1浓缩;以及 返回单元4，将浓缩单元3中集中的浓缩液W2返回到存储单元2。
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公开(公告)号：US20150257701A1
公开(公告)日：2015-09-17
申请号：US14632906
申请日：2015-02-26
Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION , PUBLIC UNIVERSITY CORPORATION OSAKA CITY UNIVERSITY , ADVANTEST CORPORATION
Inventor： Hiromichi HORINAKA , Hiroyasu MORIKAWA
CPC classification number: A61B5/4872 , A61B8/085 , A61B8/0858 , A61B8/5207 , A61B8/5223 , A61B8/5246
Abstract: A body fat diagnostic apparatus, with which a change in the velocity of ultrasonic waves can be measured and fat can be diagnosed while suppressing the effects of a periodical change due to respiration and heartbeats of a subject, is formed of: a process unit for sequentially acquiring ultrasonic wave echo signals for a number of frames so as to form a group of B mode images; a data storage unit for storing the ultrasonic wave echo signals corresponding to the groups of B mode images; a sampling unit for sampling one frame as a standard image and another frame as a comparative image through the calculation of a cross correlation; and a velocity change analyzing unit for forming an image by calculating a change in the velocity of ultrasonic waves on the basis of the ultrasonic wave echo signals corresponding to the standard image and the comparative image.
Abstract translation: 一种身体脂肪诊断装置，通过该身体脂肪诊断装置，可以测量超声波的速度变化，并且可以在抑制由于对象的呼吸和心跳引起的周期性变化的影响的同时诊断脂肪，所述装置由以下部件构成：处理单元， 获取多个帧的超声波回波信号，以形成一组B模式图像; 数据存储单元，用于存储对应于B模式图像组的超声波回波信号; 采样单元，用于通过交叉相关的计算，将一帧作为标准图像进行采样，另一帧作为比较图像; 以及速度变化分析单元，用于通过基于与标准图像和比较图像相对应的超声波回波信号计算超声波的速度的变化来形成图像。
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54.发明申请DETECTION OF BACTERIA BELONGING TO THE GENUS CAMPYLOBACTER BY TARGETING CYTOLETHAL DISTENDING TOXIN 有权通过靶向CYTOLETHAL抑制毒素检测与基因型球菌相关的细菌公开(公告)号：US20150184230A1
公开(公告)日：2015-07-02
申请号：US14052434
申请日：2013-10-11
Inventor： Shinji YAMASAKI , Worada SAMOSORUNSUK , Masahiro ASAKURA
CPC classification number: C12Q1/689 , C07K16/1203 , C07K16/121 , C07K2317/76 , C12Q2600/158 , C12Q2600/16 , G01N33/56922 , G01N2333/205 , Y02A50/451
Abstract: An objective of the present invention is to provide the cytolethal distending toxin (CDT) of C. hyointestinalis and polynucleotides encoding it, and novel methods for detection of C. hyointestinalis using the cdt genes. The present inventors focused on the cytolethal distending toxin (CDT) of Campylobacter bacteria, and detected the cdt genes of a Campylobacter-like bacterium isolated from an enteritis patient in Thailand. The present inventors discovered a bacterial strain whose cdtB gene was amplified by common primers in C. jejuni, C. coli, and C. fetus, but not by multiplex PCR that can specifically detect the cdtA, cdtB, and cdtC genes of the three bacterial species. The bacterial strain was identified as C. hyointestinalis by 16S rRNA gene analysis. Furthermore, the entire nucleotide sequence of the cdt genes was determined by genome walking upstream and downstream of the cdtB gene.
Abstract translation: 本发明的目的是提供嗜肝绞胃细胞的细胞致死性扩张毒素（CDT）和编码它的多核苷酸，以及使用cdt基因检测猪肝炎的新方法。 本发明人专注于弯曲杆菌细菌的细胞致死性扩张毒素（CDT），并检测了从泰国肠炎患者分离的弯曲杆菌样细菌的cdt基因。 本发明人发现了一种细菌菌株，其cdtB基因在空肠弯曲杆菌，大肠杆菌和C.胎儿中被普通引物扩增，但不能通过可以特异性检测三种细菌的cdtA，cdtB和cdtC基因的多重PCR扩增 种类。 通过16S rRNA基因分析将细菌菌株鉴定为嗜肝菌。 此外，cdt基因的全部核苷酸序列通过cdtB基因的上游和下游的基因组走向来测定。
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公开(公告)号：US20190198870A1
公开(公告)日：2019-06-27
申请号：US16327015
申请日：2017-08-21
Inventor： Satoru WATANO , Hideya NAKAMURA
IPC: H01M4/40 , H01M10/0525 , H01M10/054 , H01M10/0562 , H01M4/485 , H01M4/505 , H01M4/525 , H01M4/587
CPC classification number: H01M4/405 , H01M4/36 , H01M4/40 , H01M4/48 , H01M4/485 , H01M4/505 , H01M4/525 , H01M4/58 , H01M4/587 , H01M10/052 , H01M10/0525 , H01M10/054 , H01M10/0562 , H01M2004/028 , Y02E60/122 , Y02T10/7011
Abstract: A composite positive electrode active material for an all-solid-state secondary battery containing particles of a positive electrode active material and a sulfide-based solid electrolyte layer coating surfaces of the particles, wherein the composite positive electrode active material has an average roundness that is 1.3 times or more of that of a positive electrode active material at an inner core of the composite positive electrode active material.
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Patent Agency Ranking
公开(公告)号：US20190041337A1
公开(公告)日：2019-02-07
申请号：US16076637
申请日：2017-02-09
Inventor： Yoshinori Akagi , Nobuhiko Inui , Kazuhiko Imamura , Takamasa Kouno , Shigeru Nomura , Tatsuro Endo
IPC: G01N21/77 , G01N33/579
Abstract: Provided is an implement for inspection capable of measuring the concentration of a test substance with high accuracy. The implement for inspection according to the present invention is an implement for inspection used for measuring the concentration of a test substance that includes a compound for reacting with a test substance to form a granular substance or a compound which is for being bound to the test substance and is a granular substance, and a wall portion having a periodic structure on its surface.
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公开(公告)号：US10137097B2
公开(公告)日：2018-11-27
申请号：US15574651
申请日：2016-06-08
Inventor： Hidemitsu Nakajima
IPC: A61K31/16 , A61K31/10 , A61P25/28 , A61P25/16 , A61K31/164 , C07C323/57
Abstract: [Problem] Provided is a non-peptide compound which can be used as a GAPDH aggregation inhibitor. [Solution] Provided is a GAPDH aggregation inhibitor including as an active ingredient a compound represented by the chemical formula 1 wherein R1, R2, and R3 are each independently a hydrogen atom, a halogen atom, or an aliphatic hydrocarbon group having a carbon number of from 1 to 10, a polysulfurized derivative thereof, or a pharmaceutically acceptable salt thereof. The present compound has a GAPDH aggregation inhibitory activity to suppress intracerebral aggregation of various proteins involved in cerebral neurodegenerative diseases, thereby contributing to improvement in various brain neurological diseases associated with aggregation of these proteins such as Alzheimer's disease, Parkinson's disease, and cerebral infarction, and prevention of advanced seriousness of these diseases.
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公开(公告)号：US10125406B2
公开(公告)日：2018-11-13
申请号：US15108406
申请日：2014-12-28
Inventor： Yasuhiro Konishi , Norizo Saito , Masao Kishida
Abstract: The present application provides a method to recover noble metal ions by reduction with using yeast. In the method, a liquid containing noble metal ions is provided. An electron donor and yeast are added into the liquid to bring the yeast in contact with the noble metal ions to reduce the noble metal ions. The noble metal can be accumulated in a fungus body of the yeast. The electron donor can be an organic acid, a salt thereof, an alcohol and hydrogen gas.
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59.发明申请公开(公告)号：US20180214528A1
公开(公告)日：2018-08-02
申请号：US15881452
申请日：2018-01-26
Inventor： Ikuhiko NAKASE , Kosuke NOGUCHI , Nahoko BAILEYKOBAYASHI , Tetsuhiko YOSHIDA
CPC classification number: A61K39/0011 , A61K9/127 , A61K35/36 , A61K35/54
Abstract: The pharmaceutical composition for inhibiting expression of CD47 in tumor cells provided by the present invention contains: exosomes produced by cultured tumor cells in an amount effective for inhibiting expression of the CD47; and a pharmaceutically acceptable carrier.
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公开(公告)号：US09903861B2
公开(公告)日：2018-02-27
申请号：US14894452
申请日：2014-05-30
Inventor： Takuya Iida , Shiho Tokonami
IPC: G01N21/21 , G01N33/543 , G01N21/552 , G01N21/65 , G01N33/53 , G01N33/553 , C12Q1/68
CPC classification number: G01N33/54346 , C12Q1/6834 , C12Q2563/155 , C12Q2565/628 , G01N21/21 , G01N21/554 , G01N21/658 , G01N33/5308 , G01N33/553 , G01N2201/061 , G01N2201/0683
Abstract: A detection device detects an analyte that may be contained in a specimen. The detection device includes a plurality of gold nanoparticles, an optical trapping light source, an illumination light source, an objective lens, an image pick-up device, and a computation unit. The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device receives light from the liquid. The computation unit detects an analyte based on a signal received from the image pick-up device.
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