公开(公告)号：EP4212857A1

公开(公告)日：2023-07-19

申请号：EP20953146.6

申请日：2020-12-19

Applicant: Institute of Medical Devices (Suzhou) Southeast University

Inventor： GU, Zhongze ,  LI, Qiwei ,  CHEN, Zaozao

IPC: G01N21/84 ,  G01N21/01 ,  G02B21/34 ,  G02B21/06 ,  G02B21/02

Abstract: Disclosed are a photonic crystal microscope and a method of measuring cellular forces. The photonic crystal substrate includes a photonic crystal substrate, a stage, a probe light source, and an imaging assembly, the photonic crystal substrate being disposed above the stage, the probe light source and the imaging assembly being sequentially disposed at a side of the stage opposite the photonic crystal substrate, the photonic crystal substrate being configured to culture a to-be-measured cell, the photonic crystal substrate being deformable when the to-be-measured cell grows on the photonic crystal substrate; the probe light source is configured to emit probe light to the photonic crystal substrate; the photonic crystal substrate is configured to reflect the probe light to the imaging assembly; the imaging assembly is configured to receive the light reflected from the photonic crystal substrate to perform imaging, whereby force information between the to-be-measured cell and the photonic crystal substrate is obtained via a resultant image. The disclosure realizes significant increase of flux while ensuring subcellular measurement precision, simplifies algorithm complexity, enhances temporal resolution, and reduces equipment cost and experiment complexity.

公开(公告)号：EP4086827A1

公开(公告)日：2022-11-09

申请号：EP21921683.5

申请日：2021-04-28

Applicant: Southeast University

Inventor： YANG, Fan

IPC: G06Q10/06

Abstract: The present invention belongs to the field of environmental economy, and discloses a method for studying resource endowments and economic growth. The method includes the following steps: construction of a structural benchmark model, structural effect sorting, environmental effect sorting, overall growth effect and conclusion analysis. According to the present invention, through construction of a multi-path structural benchmark equation model, structural effects, environmental effects and growth effects of resource endowments affecting economic development are horizontally sorted; direct, indirect and overall actions in the different effects are longitudinally deconstructed; the multi-channel influence of natural resource endowments on economic growth is systematically analyzed; and a complex influence path of natural resources on economic growth is analyzed, and it is of great significance to transforming the economic structure, guaranteeing energy safety and constructing a resource-conserving society.

公开(公告)号：EP3989292A1

公开(公告)日：2022-04-27

申请号：EP20884449.8

申请日：2020-08-26

Applicant: Southeast University ,  CSMC Technologies Fab2 Co., Ltd.

Inventor： ZHANG, Long ,  MA, Jie ,  GU, Yan ,  ZHANG, Sen ,  ZHU, Jing ,  GONG, Jinli ,  SUN, Weifeng ,  SHI, Longxing

IPC: H01L29/739 ,  H01L29/06

Abstract: An insulated gate bipolar transistor, comprising an anode second conductivity-type region and an anode first conductivity-type region provided on a drift region (3); the anode first conductivity-type region comprises a first region (17) and a second region (16), and the anode second conductivity-type region comprises a third region (15) and a fourth region (8), the dopant concentration of the first region (17) being less than that of the second region (16), the dopant concentration of the third region (15) being less than that of the fourth region (8), the third region (15) being provided between the fourth region (8) and a body region (4), the first region (17) being provided below the fourth region (8), and the second region (16) being provided below the third region (15) and located between the first region (17) and the body region (4).

公开(公告)号：EP3884981A1

公开(公告)日：2021-09-29

申请号：EP18940745.5

申请日：2018-11-23

Applicant: Shenzhen Mindray Bio-Medical Electronics Co., Ltd. ,  Zhongda Hospital Southeast University

Inventor： LIU, Ling ,  LIU, Jinglei ,  YANG, Yi ,  ZHOU, Xiaoyong ,  QIU, Haibo ,  WAN, Congying ,  PAN, Chun ,  CHEN, Jun ,  XIE, Jianfeng

IPC: A61M16/00

Abstract: A positive end expiratory pressure (PEEP) determining method and apparatus, an aeration device, and a storage medium. The method comprises: changing a PEEP value for aeration of the aeration device to the patient stepwise (S 101); monitoring at least one physiological parameter of the patient (S 102); calculating a change in at least one physiological parameter every time the PEEP value changes (S 103); and determining a preferred PEEP value for aeration to the patient on the basis of the change in at least one physiological parameter (S 104).

公开(公告)号：EP3401464A1

公开(公告)日：2018-11-14

申请号：EP17798551.2

申请日：2017-03-30

Applicant: Southeast University

Inventor： WU, Gang ,  LI, Xinghua

IPC: E04G21/12 ,  E04C5/12 ,  E01D22/00

CPC classification number: E04G23/0244 ,  E01D22/00 ,  E04C5/12 ,  E04G21/12 ,  E04G23/0237 ,  E04G2023/0259

Abstract: An automatic tensioning system for strengthening a beam, a slab and a column by a pre-stressed FRP plate comprises a tensioning end anchor (1), a fixed end anchor (10), and a tensioning bracket (3) connected to the tensioning end anchor (1). A centre-hole jack (16) is provided in the middle of the tensioning bracket (3), a threaded rod (8) passes through the tensioning bracket (3) and is then connected to the centre-hole jack (16), and an upper toothed nut (13) and a lower toothed nut (19) respectively driven by a driving mechanism are provided on two sides of the tensioning bracket (3) on the threaded rod (8). A binary clip-type fixture (4) is further comprised, an upper surface thereof is provided with a cylinder (6), and a sleeve (7) nested outside the cylinder (6) is connected to the threaded rod (8). One end of an FRP plate (9) is clamped into the clip-type fixture (4), and the other end of the FRP plate (9) is anchored to the fixed end anchor (10). A method for strengthening a beam, a slab and a column by a pre-stressed FRP plate is also disclosed. The system saves a great deal of labour costs, and can speed up the entire construction process.

公开(公告)号：EP2502916A1

公开(公告)日：2012-09-26

申请号：EP10829544.5

申请日：2010-11-12

Applicant: Southeast University ,  Nanjing Medical University ,  Zhejiang Shapuaisi Pharmacy Ltd.

Inventor： GOU, Shaohua ,  SHEN, Hong ,  ZHANG, Yindi ,  SHEN, Jianping ,  ZHU, Yanqin ,  FENG, Luzhong ,  WU, Jianwei ,  CHEN, Dekang

IPC: C07D231/56 ,  A61K31/416 ,  A61P27/12

CPC classification number: C07D231/56

Abstract: Organic dicarboxylic acid compounds, salts and preparation methods thereof. The said compounds have activity of resisting oxidation damage to crystalline lens of eyes. The structures of the above organic dicarboxylic acid compounds are shown as formula (1).

Abstract translation: 有机二羧酸化合物，其盐及其制备方法。 所述化合物具有抵抗眼睛晶状体的氧化损伤的活性。 上述有机二羧酸化合物的结构如式（1）所示。

公开(公告)号：EP2461327A1

公开(公告)日：2012-06-06

申请号：EP09848173.2

申请日：2009-08-13

Applicant: Southeast University

Inventor： YANG, Jun ,  BAI, Na ,  LI, Jie ,  HU, Chen ,  SHI, Longxing

IPC: G11C11/00

CPC classification number: G11C11/412

Abstract: A high-density and high-robustness sub-threshold memory cell circuit, having two PMOS transistors P1 and P2 and five NMOS transistors N1∼N5, wherein, the each base electrode of the two PMOS transistors and NMOS transistors N3, N4, and N5 is connected with the local grid electrode respectively; the base electrode of the NMOS transistors N1 and N2, are grounded respectively; the NMOS transistor N1 form an phase inverter with the PMOS transistor P1, and the NMOS transistor N2 form another phase inverter with the PMOS transistor P2; the two phase inverters are connected with each other in a cross coupling manner via the cut-off NMOS transistor N5, the output end of the phase inverter N1 and P1 directly connected to the input end of the phase inverter N2 and P2, and the output end of the phase inverter N2 and P2 connected to the input end of the phase inverter N1 and P1 via the cut-off NMOS transistor N5; the NMOS transistor N3 is connected with the write bit line (WBL) of the phase inverter N1 and P1, and the NMOS transistor N4 is connected with the NOT WBL and read word line (RWL) of the phase inverter N2 and P2.

Abstract translation: 具有两个PMOS晶体管P1和P2以及五个NMOS晶体管N1¼N5的高密度和高鲁棒性子阈值存储单元电路，其中，两个PMOS晶体管和NMOS晶体管N3，N4和N5的每个基极连接 分别与本地栅电极; NMOS晶体管N1和N2的基极分别接地; NMOS晶体管N1与PMOS晶体管P1形成相位逆变器，并且NMOS晶体管N2与PMOS晶体管P2形成另一相反相器; 两相逆变器通过截止NMOS晶体管N5，直流连接到相位逆变器N2和P2的输入端的相位反相器N1和P1的输出端以交叉耦合方式相互连接，输出端 通过截止NMOS晶体管N5连接到相位反相器N1和P1的输入端的相位逆变器N2和P2的端部; NMOS晶体管N3与相位反相器N1和P1的写入位线（WBL）连接，并且NMOS晶体管N4与相位逆变器N2和P2的NOT WBL和读出字线（RWL）连接。

公开(公告)号：EP1621610A1

公开(公告)日：2006-02-01

申请号：EP04726083.1

申请日：2004-04-07

Applicant: Southeast University ,  Polifarma (Nanjingo) Co.. Ltd.

Inventor： MAO, Xi ,  MO, Yingru ,  PU, Yuepu ,  HUANG, Jinglong

IPC: C12N5/00 ,  C12N5/06 ,  C12N15/00

CPC classification number: C12N5/0606 ,  C12N15/877 ,  C12N2517/04

Abstract: The method of producing nuclear transfer embryonic stem cell by somatic cell nuclear transplantation technique is a method of producing cell by somatic cell nuclear transplantation technique, which comprises transferring the nucleus of nerve cell of adult animal into the cytoplast of enucleated embryonic stem cell of animal embryo using micromanipulator, reconstituting nuclear transfer embryonic stem cell having novel genotype, and culturing nuclear transfer embryonic stem cell to make it dissociate and proliferate up to 2 8 , which embryonic stem cell and nerve cell are allogenic, and the resultant cell is nuclear transfer embryonic stem cell having donor nuclear cell-nerve cell genotype. The present invention resolves not only the ethical problem of the use of embryonic stem cell in medicine, but also the problem of immunological rejection, which occurs in cell transplantation. It still resolves the cell cycle synchronization of donor nuclear cell and recipient nuclear cell and the source problem of recipient nuclear cell in somatic cell nuclear transplantation, so it would doubtless accelerate the development of human embryonic stem cell including the development of cell engineering and tissue engineering from this.

Abstract translation: 生产通过体细胞核移植技术，核移植胚胎干细胞的方法是通过体细胞核移植技术，包括转环成年动物的神经细胞的细胞核为动物胚胎的去核胚胎干细胞的胞质生产细胞的方法 使用微操纵器，重构具有新颖基因型核移植胚胎干细胞，并培养核移植胚胎干细胞，使其解离和增殖多达2 8，其中胚胎干细胞和神经细胞是同种异体，将所得的细胞是核移植胚胎干 有供体细胞核的细胞神经细胞的基因型。 本发明不仅有效地解决了使用中医药的胚胎干细胞，所以，但免疫排斥的麻烦，它在细胞移植中发生问题的伦理。 它仍然解析供体核细胞和受体核细胞和源的体细胞核移植接受者核细胞问题的细胞周期同步，因此它无疑将加速人类胚胎干细胞，包括细胞工程和组织工程的发展而发展 源于此。

公开(公告)号：US20250155569A1

公开(公告)日：2025-05-15

申请号：US18940840

申请日：2024-11-08

Applicant: Southeast University

Inventor： Yanan DU ,  Decheng FENG ,  Gang WU

IPC: G01S13/90 ,  G06T7/11 ,  G06T7/521 ,  G06T7/55 ,  G06T17/05 ,  G06V20/10 ,  G06V20/17 ,  G06V20/50

Abstract: The present invention discloses a method and system for evaluating post-earthquake damage of building groups based on interferometric synthetic aperture radar (InSAR). Method includes: determining an investigation region, acquiring pre- and post-earthquake radar images of a corresponding district, and acquiring radar datasets included in radar images; acquiring a radar line-of-sight (LOS)-direction deformation map of investigation region by processing pre- and post-earthquake radar images using D-InSAR; acquiring a deformation in a main earthquake direction by decomposing an LOS-direction deformation; drawing a deformation classification map of buildings; acquiring pre- and post-earthquake optical remote sensing images of investigation region, and locating post-earthquake collapsed buildings; locating collapsed buildings in deformation classification map, comparing optical remote sensing images with deformation classification map, and locating exact positions of collapsed buildings; and evaluating post-earthquake damage of the buildings by evaluating post-earthquake damage conditions based on position information of collapsed buildings and the deformation classification map.

公开(公告)号：US20250122633A1

公开(公告)日：2025-04-17

申请号：US18940787

申请日：2024-11-07

Applicant: SOUTHEAST UNIVERSITY

Inventor： Xuhai ZHANG ,  Tongheng WANG ,  Yuqiao ZENG ,  Peng CUI ,  Chongyang BA ,  Feng FANG ,  Qiyue SHAO ,  Haoran ZHENG ,  Pengcheng ZHAO ,  Jianqing JIANG

IPC: C25B11/089 ,  C22C30/02 ,  C25B11/031 ,  C25D3/56 ,  C25D5/00 ,  C25D5/48

Abstract: Six-membered high-entropy foam for hydrogen production by water splitting and preparation method are provided. The foam consists of Ni, Fe, Cu, Co, Mo, and Pt, comprising 10 at %-25 at % of Ni, 10 at %-25 at % of Fe, 10 at %-25 at % of Cu, 10 at %-25 at % of Co, 10 at %-25 at % of Mo, and 10 at %-25 at % of Pt. Catalyst loading of the foam can reach a range of 0.8 mg/cm2-3.2 mg/cm2, which is much higher than the effective catalyst loading of most nano-catalysts. When used as catalyst for hydrogen production by water splitting, the hydrogen evolution overpotential of the surface of the six-membered high-entropy foam is within a range of 36 mV-60 mV, and the foam operates stably at industrial-level current density (500 mA/cm2). The preparation method does not require harsh environment such as high temperature or high vacuum, making the method simple and easy to implement, with low-cost raw materials.