公开(公告)号：KR1020100055733A

公开(公告)日：2010-05-27

申请号：KR1020080114594

申请日：2008-11-18

Applicant: (주)아모레퍼시픽

Inventor： 박준성 ,  박혜윤 ,  김동현 ,  이상민 ,  신동욱 ,  김신형 ,  노민수 ,  김덕희 ,  김한곤

IPC: A61K31/366 ,  A61K31/352 ,  A61P17/00

CPC classification number: A61K31/352 ,  A61K9/0014 ,  A61K31/366

Abstract: PURPOSE: An external use skin composition containing ortho-dihydroxyisoflavone derivative is provided to improve expression of DKK3 proein and FZD1 protein and to suppress hyperproliferation. CONSTITUTION: An external use skin composition for suppressing epidermis hyperproliferation and treating inflammatory skin diseases contains 0.001-30 weight% of ortho-dihydroxyisoflavone derivative, 4'6,7-trihydroxy isoflavone, 3',4'7-trihydroxyisoflavone, or mixture thereof as an active ingredient. The composition is used in the form of skin softener, astringent, lotion, eye cream, massage cream, cleansing cream, cleansing foam, cleansing water, powder, essence, or pack.

Abstract translation: 目的：提供含有邻二羟基异黄酮衍生物的外用皮肤组合物，以改善DKK3 proein和FZD1蛋白的表达，抑制过度增殖。 构成：用于抑制表皮过度增殖和治疗炎性皮肤病的外用皮肤组合物含有0.001-30重量％的邻二羟基异黄酮衍生物，4'6,7-三羟基异黄酮，3'，4,7-二羟基异黄酮，或其混合物 活性成分。 该组合物以皮肤柔软剂，收敛剂，洗剂，眼霜，按摩霜，清洁霜，清洁泡沫，清洁水，粉末，精华或包装的形式使用。

公开(公告)号：KR1020100042708A

公开(公告)日：2010-04-27

申请号：KR1020080101820

申请日：2008-10-17

Applicant: (주)아모레퍼시픽

Inventor： 이상민 ,  신동욱 ,  이찬우 ,  김한성 ,  김진웅 ,  김신형 ,  노민수 ,  김한곤

IPC: A61K31/352 ,  A61Q19/00

Abstract: PURPOSE: A composition containing amentoflavone as an active ingredient is provided to increase alpha-6 integrin and to promote kerationcyte stem cell proliferation. CONSTITUTION: A composition for promoting skin regeneration contains amentoflavone as an active ingredient of formula 1. The composition is a cosmetic composition. A cosmetic composition contains 0.001-10 weight% of amentoflavone. The cosmetic composition is contained in lotion type, cream type, and pack type formulation. The composition also is a pharmaceutical composition. The pharmaceutical composition contains 0.001-10 weight% of amentoflavone. The pharmaceutical composition is contained in soft capsule, tablet, or granule.

Abstract translation: 目的：提供含有黄酮黄酮作为活性成分的组合物以增加α-6整联蛋白并促进细胞干细胞增殖。 构成：用于促进皮肤再生的组合物含有作为式1的有效成分的黄酮黄酮。组合物是化妆品组合物。 化妆品组合物含有0.001-10重量％的叶黄酮。 化妆品组合物包含在洗剂型，奶油型和包装型制剂中。 组合物也是药物组合物。 药物组合物含有0.001-10重量％的黄酮黄酮。 药物组合物包含在软胶囊，片剂或颗粒中。

公开(公告)号：KR1020100012076A

公开(公告)日：2010-02-05

申请号：KR1020080073605

申请日：2008-07-28

Applicant: (주)아모레퍼시픽

Inventor： 박선미 ,  신동욱 ,  이상민 ,  송민정 ,  김신형 ,  노민수 ,  김한곤

IPC: A61K8/97 ,  A61K35/28 ,  A61Q19/08

CPC classification number: A61K8/97 ,  A61K35/28 ,  A61Q19/08

Abstract: PURPOSE: A composition containing medicinal herb extract for skin care or plastic surgery is provided to promote differentiation of human mesenchymal stem cells to adipocytes and improve adipose. CONSTITUTION: A composition for promoting differentiation of adipocytes contains Crassirhizomae Rhizoma, Linderae Radix, Cinnamomum cassia, and Saphora flavescens extract as an active ingredient. The medicinal herb extract is obtained using organic solvent such as water and ethanol. The composition enhances adipose. The composition promotes differentiation of human mesenchymal stem cells to adipocytes. The composition is used in the form of skin softener, nutrition lotion, massage cream, pack, gel, or skin viscosity type cosmetic product.

Abstract translation: 目的：提供含有用于护肤或整形手术的药用草药提取物的组合物，以促进人类间充质干细胞向脂肪细胞分化并改善脂肪。 构成：用于促进脂肪细胞分化的组合物含有Crassirhizomae Rhizoma，Linderae Radix，Cinnamomum Cassia和Saphora flavescens提取物作为活性成分。 使用有机溶剂如水和乙醇获得草药提取物。 组合物增强脂肪。 该组合物促进人间充质干细胞向脂肪细胞的分化。 该组合物以皮肤柔软剂，营养乳液，按摩霜，包装，凝胶或皮肤粘度型化妆品的形式使用。