-
公开(公告)号：KR1020140133795A
公开(公告)日：2014-11-20
申请号：KR1020140139600
申请日：2014-10-16
Applicant: (주)아모레퍼시픽
IPC: A61K8/97 , A61K36/483 , A61Q19/00 , A61P17/00
Abstract: 본 발명은 인간 중간엽 줄기세포의 지방세포로의 분화를 촉진하는 조성물에 관한 것으로, 보다 상세하게는 건율, 권백, 노회, 단삼, 박하, 반하, 소맥, 어성초, 원지 및 조각인 추출물 중 1종 이상을 유효성분으로 함유하여 인간 중간엽줄기세포를 지방세포로 분화하는 것을 촉진시킴으로써 지방체(Lipid droplet)를 생성하여, 특정 부위의 피부의 볼륨감을 증대시키는 미용 또는 성형용 조성물에 관한 것이다.
Abstract translation: 本发明涉及促进人类间充质干细胞向脂肪细胞分化的组合物，更具体地说，涉及一种化妆品或整容手术组合物，其包括蓖麻，s ella，芦荟，薄荷， ，小麦，葫芦科，枸杞子和Gleditsiae Semen提取物作为活性成分，促进人间质干细胞分化为脂肪细胞，并产生脂滴，从而增加皮肤特定面积的体积。
-
公开(公告)号：KR1020140064593A
公开(公告)日：2014-05-28
申请号：KR1020130040842
申请日：2013-04-15
Applicant: (주)아모레퍼시픽
Abstract: The specification provides a light source irradiator which irradiates visible light, a kit for lipolysis with a manual described with a method for lipolysis by irradiating visible light, and a slimming method for irradiating visible light to the skin. According to the specification, the method can safely and effectively dissolve fat by dissolving triglyceride in fat cells by irradiating light with a visible light wavelength harmless to a human body and can be used for a slimming method since the method is more economical and convenient than an existing lipolysis method.
Abstract translation: 本说明书提供了照射可见光的光源照射器，用用于通过照射可见光的脂肪分解方法描述的手动进行脂肪分解的试剂盒，以及用于将可见光照射到皮肤上的减肥方法。 根据本说明书，该方法可以通过用对人体无害的可见光波长的光照射而将甘油三酯溶解在脂肪细胞中而可以安全有效地溶解脂肪，并且可以用于减肥方法，因为该方法比一种方法更经济和方便 现有脂肪分解法。
-
公开(公告)号：KR101349187B1
公开(公告)日：2014-01-10
申请号：KR1020060121955
申请日：2006-12-05
Applicant: (주)아모레퍼시픽
IPC: A61K31/12 , A61K31/05 , A61K31/136 , A61P3/04
Abstract: 본 발명은 지방대사 이상질환의 치료 및 예방용 약학 조성물에 관한 것으로, 화학식 1의 화합물을 유효성분으로 포함하는 본 발명의 약학 조성물은 인간 간세포에서 생체내 에너지 대사에 중요한 역할을 하는 아이소싸이트레이트 탈수소효소 3α (IDH3α) 프로모터와 카르니틴 팔미토일 트랜스퍼레이즈 1A (CPT1A) 프로모터의 활성을 증가시켜, 혈당 및 중성지방의 감소 및 결과적으로 체중의 감소를 가져오므로, 비만, 고지혈증, 당뇨병 등의 지방대사 이상질환의 예방 및 치료에 유용하게 사용될 수 있다.
-
公开(公告)号：KR1020130142814A
公开(公告)日：2013-12-30
申请号：KR1020120066352
申请日：2012-06-20
Applicant: (주)아모레퍼시픽
Abstract: The present invention relates to a medium composition for adult stem cells derived from dermis maintaining the stemness of the adult stem cells, and a culturing method of the adult stem cells. The composition contains 10-50 ng/ml of more than one compound selected from the group consisting of VEGF-D, activin-A, and activin-AB for the total volume of the composition. [Reference numerals] (AA) Relative expression amount of Sox2;(BB,EE) Control group;(CC,FF) Relative expression amount of Nanog;
Abstract translation: 本发明涉及一种维持成体干细胞干细胞的真皮成体干细胞培养基组合物和成体干细胞的培养方法。 组合物含有10-50ng / ml多于一种选自组合物总体积的VEGF-D，激活素-A和激活素-AB的化合物。 （AA）相对表达量的Sox2;（BB，EE）对照组;（CC，FF）相对表达量的Nanog;
-
公开(公告)号：KR1020130132508A
公开(公告)日：2013-12-04
申请号：KR1020137016899
申请日：2011-01-03
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q19/00 , A61K8/97 , A61K36/58 , A61K36/62 , A61K2300/00
Abstract: The present invention relates to a composition for combating oxidation and alleviating detrimental effects on skin caused by yellow sand including a Meliae Cortex extract and a lotus flower extract, and more specifically, the present invention includes a Meliae Cortex extract and a lotus flower extract, detoxicates and discharges a toxin by increasing the expression of NQO1 which is an enzyme for detoxicating a toxin and GSTT1 which is an enzyme for discharging a toxin, protects the skin by increasing the expression of antimicrobial peptide hBD3 which is a natural immune factor, and protects the skin and suppresses aging by suppressing the generation of active oxygen by increasing the expression of anti-oxidizing protein of GPX1, catalase, Trx1, and Prdx1.
Abstract translation: 本发明涉及一种用于抵抗氧化并减轻由黄砂（包括堇菜皮提取物和莲花提取物）引起的对皮肤的有害影响的组合物，更具体地说，本发明包括Meliae Cortex提取物和莲花提取物，解毒 并通过增加作为毒素解毒酶的NQO1的表达和作为排出毒素的酶的GSTT1的表达来释放毒素，通过增加作为天然免疫因子的抗微生物肽hBD3的表达来保护皮肤，并保护 通过增加GPX1，过氧化氢酶，Trx1和Prdx1的抗氧化蛋白的表达来抑制活性氧的产生来抑制老化。
-
Patent Agency Ranking
公开(公告)号：KR101309335B1
公开(公告)日：2013-09-16
申请号：KR1020110064247
申请日：2011-06-30
Applicant: (주)아모레퍼시픽
IPC: A61K38/16 , A61K31/7105 , A61P17/00
Abstract: 본 발명은 miRNA-526b 기능의 저해제(inhibitor)로 작용하는 올리고뉴클레오티드 또는 모방체(mimic)로 작용하는 올리고뉴클레오티드를 포함하는 콜라겐 조절용 조성물을 제공한다. 본 발명의 조성물은 콜라겐 분해효소(collagenase) 중의 하나인 MMP1(matrix metalloproteinase 1)의 발현을 조절하여 진피층을 채우는 콜라겐 생성을 조절하므로 노화 개선, 예방 또는 치료에 사용될 수 있다.
-
公开(公告)号：KR1020130030833A
公开(公告)日：2013-03-28
申请号：KR1020110094352
申请日：2011-09-20
Applicant: (주)아모레퍼시픽
IPC: A61K36/9066 , C12N5/0775 , A61P17/00
Abstract: PURPOSE: An external use skin composition is provided to promote differentiation of mesenchymal stem cells into adipocytes, to enhance skin elasticity, and to improve anti-wrinkling effect. CONSTITUTION: An external use skin composition for promoting differentiation into adipocytes contains 0.0001-30 wt% of a Curcuma longa extract as an active ingredient. The composition promotes differentiation of mesenchymal stem cells into adipocytes. The mesenchymal stem cell is a human mesenchymal stem cell. A pharmaceutical composition for promoting differentiation into adipocytes contains the Curcuma longa extract as an active ingredient. [Reference numerals] (AA) Relative differentiation rate; (BB) Negative control group; (CC) Borneolum; (DD) Achuranthis Radix; (EE) Curcumae longae Rhizoma
Abstract translation: 目的：提供外用皮肤组合物，以促进间充质干细胞分化为脂肪细胞，增强皮肤弹性，改善抗皱效果。 构成：用于促进脂肪细胞分化的外用皮肤组合物含有0.0001-30重量％的姜黄提取物作为活性成分。 该组合物促进间充质干细胞分化为脂肪细胞。 间充质干细胞是人间充质干细胞。 用于促进脂肪细胞分化的药物组合物含有姜黄提取物作为活性成分。 （附图标记）（AA）相对分化率; （BB）阴性对照组; （CC）冰片; （DD）Achuranthis Radix; （EE）Curcumae longae Rhizoma
-
公开(公告)号：KR1020130030546A
公开(公告)日：2013-03-27
申请号：KR1020110094094
申请日：2011-09-19
Abstract: PURPOSE: A light emitting apparatus for a thermostatic chamber is provided to effectively release heat generated by a light source and to constantly maintain temperature, humidity, and CO2 concentration. CONSTITUTION: A light emitting apparatus for a thermostatic chamber comprises: a light source(10) for irradiating by light; a housing(20) which surrounds the light source and releases the heat generated from the light source; a heat sink(30) which is mounted outside the housing and stores and releases the heat; and a heat buffer member(40) which is placed between the housing and heat sink and has lower thermal conduction rate than the housing and the heat sink. The housing, the heat sink, and the heat buffer member are formed of a metal material.
Abstract translation: 目的：提供一种用于恒温室的发光装置，以有效地释放由光源产生的热量并且恒定地保持温度，湿度和CO 2浓度。 构成：用于恒温室的发光装置包括：用于照射光的光源（10）; 壳体（20），其围绕光源并释放从光源产生的热量; 散热器（30），其安装在所述壳体外部并储存和释放热量; 以及放置在壳体和散热器之间的热缓冲构件（40），并且具有比壳体和散热器更低的导热率。 壳体，散热器和热缓冲构件由金属材料形成。
-
59.发明公开비피더스균 추출물을 함유하는 지방유래 줄기세포의 줄기세포성 증진용 및 피부세포 증식용 조성물 有权用于促进ADIPOSE衍生的干细胞和增加含有双歧杆菌提取物的皮肤细胞的稳定性的化妆品组合物
公开(公告)号：KR1020120058864A
公开(公告)日：2012-06-08
申请号：KR1020100120371
申请日：2010-11-30
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing Bifidobacteria extract is provided to enhance the stemness of stem cells and to enhance adipose for beauty. CONSTITUTION: A composition for enhancing the stemness of adipose-derived stem cells contains 0.0001-10 wt% of Bifidobacteria extract as an active ingredient. The stem cell is human adipose-derived stem cells(hADSCs). A composition for enhancing skin cells contains 0.0001-10 wt% of extract as an active ingredient. The skin cells are keratinocyte stem cells(KSCs) or transit-amplifying cells(TA cells). The extract is prepared by culturing and crushing the bacteria with a homogenizer.
Abstract translation: 目的：提供含有双歧杆菌提取物的组合物，以增强干细胞的干性和增强美容的脂肪。 构成：用于增强脂肪干细胞的干性的组合物含有0.0001-10重量％的双歧杆菌提取物作为活性成分。 干细胞是人类脂肪来源的干细胞（hADSCs）。 用于增强皮肤细胞的组合物含有0.0001-10重量％的提取物作为活性成分。 皮肤细胞是角质形成细胞干细胞（KSC）或转运扩增细胞（TA细胞）。 通过用均化器培养和破碎细菌来制备提取物。
-
公开(公告)号：KR1020120026689A
公开(公告)日：2012-03-20
申请号：KR1020100088716
申请日：2010-09-10
Applicant: (주)아모레퍼시픽
IPC: A61K36/282 , A61K8/97 , C12N5/077 , A61Q19/08
CPC classification number: A61K36/282 , A61K8/97 , A61K2800/86 , A61Q19/08 , C12N5/0669 , C12N2506/1353
Abstract: PURPOSE: A composition for promoting human mesenchymal stem cell differentiation is provided to enhance skin volume and elasticity and to improve anti-wrinkling. CONSTITUTION: An external use skin composition for promoting adipocytes contains 0.0001-30 wt% of Artemisia asiatica extract as an active ingredient. The composition promotes differentiation of mesenchymal stem cells into adipocytes. The mesenchymal stem cells are derived from human body. A pharmaceutical composition for promoting differentiation into adipocytes contains the extract as an active ingredient. The dose of the extract is 0.001 mg/kg/day-2,000 mg/kg/day.
Abstract translation: 目的：提供促进人间质干细胞分化的组合物，以增强皮肤体积和弹性，并改善抗皱纹。 构成：用于促进脂肪细胞的外用皮肤组合物含有0.0001-30重量％的亚洲艾蒿提取物作为活性成分。 该组合物促进间充质干细胞分化为脂肪细胞。 间充质干细胞来源于人体。 用于促进脂肪细胞分化的药物组合物含有提取物作为活性成分。 提取物的剂量为0.001mg / kg /天-2000mg / kg /天。
-
-
-
-
-
-
-
-
-
Search Results
155
records
(took 0.035 seconds)
