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公开(公告)号:KR1020120037613A
公开(公告)日:2012-04-20
申请号:KR1020100099169
申请日:2010-10-12
Applicant: 박사룡
Inventor: 박사룡
Abstract: PURPOSE: A novel type band-aid containing lysozyme without causing tolerance is provided to sterilize bacteria by hydrolyzing substances forming the cell membrane of the bacteria. CONSTITUTION: A novel type band-aid containing lysozyme includes a supporting body(1), a drug layer(2), and a releasing film(3). The supporting body includes an adhesive and a lysozyme hydrochloride layer. The lysozyme hydrochloride layer is formed by soaking a piece of gauze or cotton with a solution of lysozyme hydrochloride, or spreading the lysozyme hydrochloride solution on the gauze or the cotton.
Abstract translation: 目的:提供一种不引起耐受性的含有溶菌酶的新型助剂,通过水解形成细菌细胞膜的物质对细菌进行灭菌。 构成:含有溶菌酶的新型助剂包括支撑体(1),药物层(2)和脱模膜(3)。 支撑体包括粘合剂和盐酸溶菌酶层。 通过将一块纱布或棉布与溶菌酶盐酸盐溶液浸泡,或将溶菌酶盐酸盐溶液铺展在纱布或棉布上形成盐酸溶菌酶层。
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公开(公告)号:KR1020110050881A
公开(公告)日:2011-05-17
申请号:KR1020090107454
申请日:2009-11-09
Applicant: 박사룡
Inventor: 박사룡
IPC: C07D403/12 , C07D401/12 , C07D403/02
Abstract: PURPOSE: A composition containing non-hygroscopic acid addition salt of (S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid is provided to ensure anti-histamine activity and anti-allergic activity. CONSTITUTION: A novel pivalate of (S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic acid is a compound I and is stable without hygroscopicity. A pharmaceutical composition contains the novel pivalate as an active ingredient. A method for preparing the pivalate comprises: a step of dissolving a compound of structural formula I in an organic solvent of methyl acetate, ethyl acetate, chloroform, benzene, acetonitrile, methanol, and ethanol; a step of reacting with toluic acid or toluene sulfonic acid; and a step of concentrating and crystallizing.
Abstract translation: 目的:提供含(S)-4- [4 - [(4-氯苯基)(2-吡啶基)甲氧基]哌啶子基]丁酸的非吸湿性酸加成盐的组合物,以确保抗组胺活性和抗过敏 活动。 构成:(S)-4- [4 - [(4-氯苯基)(2-吡啶基)甲氧基]哌啶子基]丁酸的新颖的新戊酸是化合物I,并且在没有吸湿性的情况下是稳定的。 药物组合物含有新戊酸酯作为活性成分。 一种制备新戊酸的方法包括:将结构式I的化合物溶于乙酸甲酯,乙酸乙酯,氯仿,苯,乙腈,甲醇和乙醇的有机溶剂中的步骤; 与甲苯甲酸或甲苯磺酸反应的步骤; 和浓缩和结晶的步骤。
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