公开(公告)号：KR101355019B1

公开(公告)日：2014-01-27

申请号：KR1020130022853

申请日：2013-03-04

Applicant: 한국과학기술연구원

Inventor： 김상경

IPC: G01Q60/38 ,  C07H21/00 ,  G01Q70/16

CPC classification number: G01Q60/40 ,  C07H21/00 ,  G01Q70/04 ,  G01Q70/18

Abstract: The present invention provides a cantilever sensor, for atomic force microscopy, having a cantilever including nucleic acid fixing unit in which nucleic acid is fixed in a lower end thereof and a manufacturing method for the same. According to the present invention, a probe tip can be used for one time by using a detachable probe tip according to temperature control, a method for attaching and detaching is very simple and economical, and is effectively applied to an array and a finger by simultaneously combining numerous sequences since DNA combination is selectively occurred.

Abstract translation: 本发明提供一种用于原子力显微镜的悬臂式传感器，其具有包括核酸固定在其下端的核酸定影单元的悬臂及其制造方法。 根据本发明，通过使用根据温度控制的可拆卸探针尖端可以使用探针尖端，附接和分离的方法非常简单和经济，并且同时被有效地应用于阵列和手指 结合许多序列，因为选择性地发生DNA组合。

公开(公告)号：KR1020130042341A

公开(公告)日：2013-04-26

申请号：KR1020110106589

申请日：2011-10-18

Applicant: 한국과학기술연구원

Inventor： 김상경 ,  박상휘

IPC: C23C18/42 ,  B82B3/00

CPC classification number: C22C5/02 ,  B22F1/0018 ,  B22F1/0062 ,  B22F2001/0037 ,  B22F2999/00 ,  B82Y30/00 ,  B82Y40/00 ,  C23C18/54 ,  G01N21/658 ,  B22F9/16 ,  C23C18/00

Abstract: PURPOSE: A manufacturing method for gold nanostructure using an electroless displacement plating method are provided to uniformly manufacture gold nanostructure on a large area, to manufacture without other mediators, and to facilitate to manufacture gold nanostructure without applying electric energy. CONSTITUTION: A manufacturing method for gold nanostructure using an electroless displacement plating method comprises the following steps: forming a metal layer by evaporating a metal with lower reduction potential than gold to a substrate; and reacting a plating solution which contains gold ions with the metal layer. The metal with lower reduction potential than gold indicates Ni, Pt, Ag, or Cu. The gold nanostructure is a nanoflower or nanolawns structure. [Reference numerals] (AA) Plating solution; (BB) Reaction in the solution; (CC) Seed metal ion; (DD) Au ion; (EE) Metal; (FF) Substrate; (GG) Metal nanostructure;

Abstract translation: 目的：提供一种使用无电位移镀法的金纳米结构的制造方法，以在大面积上均匀地制造金纳米结构，无需其他介体制造，并且有助于在不施加电能的情况下制造金纳米结构。 构成：使用无电位移镀法的金纳米结构的制造方法包括以下步骤：通过将具有比金的还原电位低的金属蒸发至基底来形成金属层; 并使含有金离子的镀液与金属层反应。 比金还原电位低的金属表示Ni，Pt，Ag或Cu。 金纳米结构是纳米花或纳米结构。 （附图标记）（AA）电镀液; （BB）溶液中的反应; （CC）种子金属离子; （DD）Au离子; （EE）金属; （FF）基材; （GG）金属纳米结构;

公开(公告)号：KR1020100052611A

公开(公告)日：2010-05-20

申请号：KR1020080111411

申请日：2008-11-11

Applicant: 한국과학기술연구원

Inventor： 황교선 ,  김태송 ,  김상경 ,  조원우

IPC: B81B7/02 ,  B81C1/00 ,  G01N33/00

Abstract: PURPOSE: A cantilever sensor, a manufacturing method thereof, bio material detecting apparatus using the sensor and a manufacturing method of the detecting apparatus are provided to measure the bio material collected in a cantilever in a quantitative manner through the power value applied to the upper and lower electrodes. CONSTITUTION: A cantilever sensor(110) comprises a front end section and a rear end section. The front end section is arranged at the location corresponding to the reference electrode. The front end section includes the electrode for the capacitance measurement. The capacitance measurement electrode is sequentially deposited by a bottom electrode, an insulating film(103) and an upper electrode(113a). At the rear end section, a bottom electrode(111), a piezoelectric film(112), and an upper electrode(113b) are successively deposited. The upper electrode of the capacitance measurement electrode is electrically insulated from the piezoelectric film. A protective film(104) is formed on the front side including the upper electrode.

Abstract translation: 目的：提供一种悬臂传感器及其制造方法，使用传感器的生物材料检测装置和检测装置的制造方法，通过施加到上部的功率值定量地测量悬臂中收集的生物材料， 下电极。 构成：悬臂传感器（110）包括前端部分和后端部分。 前端部配置在与参照电极对应的位置。 前端部分包括用于电容测量的电极。 电容测量电极由底部电极，绝缘膜（103）和上部电极（113a）依次沉积。 在后端部分，依次沉积底部电极（111），压电膜（112）和上部电极（113b）。 电容测量电极的上电极与压电膜电绝缘。 在包括上电极的前侧形成保护膜（104）。

公开(公告)号：KR1020100050071A

公开(公告)日：2010-05-13

申请号：KR1020080109184

申请日：2008-11-05

Applicant: 한국과학기술연구원

Inventor： 김태송 ,  황교선 ,  김상경

IPC: G01N33/50 ,  G01N33/48 ,  G01N33/68

Abstract: PURPOSE: A detection system of very small amount of biomass using a micro=cantilever is provided to improve detection sensitivity by amplifying output signal change and to easily perform protein analysis. CONSTITUTION: A micro-cantilever sensor-based protein detection system comprises: a micro-cantilever sensor; a monoclonal primary antibody layer which binds to one epitope; a protein layer formed on the monoclonal primary antibody layer; The system further comprises a self-assembled monolayer(SAM) between micro-cantilever sensor and monoclonal primary antibody layer. The micro-cantilever sensor contains PZT layer and comprises a gilt layer at lower side of the micro-cantilever sensor. The self-assembled monolayer comprises calixcrown, 11-mercaptoundecanoic acid, or thioctic acid.

Abstract translation: 目的：提供使用micro =悬臂的极小量生物质的检测系统，通过放大输出信号变化和轻松进行蛋白质分析来提高检测灵敏度。 构成：基于微悬臂传感器的蛋白质检测系统包括：微悬臂传感器; 结合一个表位的单克隆一级抗体层; 形成在单克隆一抗层上的蛋白质层; 该系统还包括微悬臂传感器和单克隆一级抗体层之间的自组装单层（SAM）。 微悬臂传感器包含PZT层，并在微悬臂传感器的下侧包括镀金层。 自组装单层包括杯状，11-巯基十一烷酸或硫辛酸。