公开(公告)号：US20230018499A1

公开(公告)日：2023-01-19

申请号：US17862991

申请日：2022-07-12

Applicant: LightLab Imaging, Inc.

Inventor： Justin Akira Blaber ,  Ajay Gopinath ,  Humphrey Chen ,  Kyle Edward Savidge ,  Angela Zhang ,  Gregory Patrick Amis

IPC: G06T7/00 ,  G16H50/20 ,  G16H30/40

Abstract: Aspects of the disclosure relate to systems, methods, and algorithms to train a machine learning model or neural network to classify OCT images. The neural network or machine learning model can receive annotated OCT images indicating which portions of the OCT image are blocked and which are clear as well as a classification of the OCT image as clear or blocked. After training, the neural network can be used to classify one or more new OCT images. A user interface can be provided to output the results of the classification and summarize the analysis of the one or more OCT images.

公开(公告)号：US11311200B1

公开(公告)日：2022-04-26

申请号：US16186040

申请日：2018-11-09

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Samir Farah ,  Johan Svanerudh

IPC: A61B5/0215 ,  A61B5/02 ,  A61B5/00 ,  A61B5/026

Abstract: In part, the disclosure relates to computer-based methods, and systems suitable for evaluating a subject to determine the appropriate diagnostic tools for assessing coronary arteries. This can include assessing various blood pressure values during a resting state (without inducing hyperemia). These systems and methods can assess a patient and identify coronary dominance on per patient basis. In turn, this assessment can be used to recommend whether a resting index is appropriate or if another index such as FFR or others such be obtained diagnostic metric such as a pressure value-based ratio.

公开(公告)号：US20210085275A1

公开(公告)日：2021-03-25

申请号：US17025473

申请日：2020-09-18

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: A61B6/00 ,  A61B5/0402 ,  A61B90/00

Abstract: Aspects of the disclosure relate to the combination and display of both live and non-live patient images. The features described include collecting angiographic image data, and correlating angiographic image frames to time-varying data relating to the patient's heart cycle. This time-varying data may then be compared with the patient's live heart cycle data so that the collected angiographic image frames can be interlaced within a display of live fluoroscopic images of the patient.

公开(公告)号：US20210042927A1

公开(公告)日：2021-02-11

申请号：US16985623

申请日：2020-08-05

Applicant: LightLab Imaging, Inc.

Inventor： Gregory Patrick Amis ,  Ajay Gopinath ,  Mark Hoeveler

IPC: G06T7/00 ,  G06T11/00 ,  G06T7/38 ,  G16H50/30 ,  G16H30/40 ,  G16H50/50 ,  A61B5/02 ,  A61B5/00

Abstract: The present disclosure provides systems and methods to receiving OCT or IVUS image data frames to output one or more representations of a blood vessel segment. The image data frames may be stretched and/or aligned using various windows or bins or alignment features. Arterial features, such as the calcium burden, may be detected in each of the image data frames. The arterial features may be scored. The score may be a stent under-expansion risk. The representation may include an indication of the arterial features and their respective score. The indication may be a color coded indication.

公开(公告)号：US20200294659A1

公开(公告)日：2020-09-17

申请号：US16821877

申请日：2020-03-17

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Mark Hoeveler

IPC: G16H40/63 ,  G06T7/13 ,  G06K9/78 ,  G06T7/62 ,  G06T7/00 ,  G16H30/20 ,  G16H30/40 ,  G16H40/40 ,  A61B34/10 ,  A61B34/00 ,  G06F3/0484

Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.

公开(公告)号：US20200167923A1

公开(公告)日：2020-05-28

申请号：US16778252

申请日：2020-01-31

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: G06T7/00 ,  G06T5/00 ,  A61B5/00 ,  A61B5/02 ,  G06T7/13 ,  G06T7/11

Abstract: In part, the disclosure relates to an automated method of branch detection with regard to a blood vessel imaged using an intravascular modality such as OCT, IVUS, or other imaging modalities. In one embodiment, a representation of A-lines and frames generated using an intravascular imaging system is used to identify candidate branches of a blood vessel. One or more operators such as filters can be applied to remove false positives associated with other detections.

公开(公告)号：US10338795B2

公开(公告)日：2019-07-02

申请号：US15219197

申请日：2016-07-25

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Denis Dion ,  Christopher E. Griffin ,  Desmond Adler

IPC: G06T7/00 ,  G06F3/0484 ,  A61B34/10 ,  A61B5/00 ,  A61B34/20 ,  A61B8/12 ,  G06T15/08 ,  G06T19/00 ,  G06F3/0481 ,  A61B5/02 ,  G16H30/40 ,  G16H50/20 ,  G16H20/40

Abstract: In part, the disclosure relates to intravascular data collection systems and the software-based visualization and display of intravascular data relating to detected side branches and detected stent struts. Levels of stent malapposition can be defined using a user interface such as a slider, toggle, button, field, or other interface to specify how indicia are displayed relative to detected stent struts. In addition, the disclosure relates to methods to automatically provide a two or three-dimensional visualization suitable for assessing side branch and/or guide wire location during stenting. The method can use one or more a computed side branch location, a branch takeoff angle, one or more stent strut locations, and one or more lumen contours.

公开(公告)号：US10222956B2

公开(公告)日：2019-03-05

申请号：US14975671

申请日：2015-12-18

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Subhan Khan ,  Denis Dion

IPC: G06F3/0484 ,  A61B5/00 ,  A61B5/02 ,  G06T19/00

Abstract: In part, the disclosure relates to intravascular data collections and generation of representations thereof include one or more view of regions associated with side branches or arteries such as a carina or bifurcation. In one embodiment, accessing a set of intravascular data stored in machine readable memory; performing side branch detection with regard to the intravascular data to identify one or more side branches; and identifying a plurality of frames for the one or more side branches is performed. An automatic viewing angle that is toggleable is used in one embodiment.