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    METHOD FOR DIAGNOSING PROSTATE CANCER
    51.
    发明申请
    METHOD FOR DIAGNOSING PROSTATE CANCER 审中-公开
    诊断前列腺癌的方法

    公开(公告)号：WO2004031414A3

    公开(公告)日：2004-07-08

    申请号：PCT/JP0312073

    申请日：2003-09-22

    Applicant: ONCOTHERAPY SCIENCE INC ,  JAPAN AS REPRESENTED BY THE PR ,  NAKAMURA YUSUKE ,  KATAGIRI TOYOMASA ,  NAKAGAWA HIDEWAKI ,  NAKATSURU SHUICHI

    Inventor： NAKAMURA YUSUKE ,  KATAGIRI TOYOMASA ,  NAKAGAWA HIDEWAKI ,  NAKATSURU SHUICHI

    IPC: C07K14/47 ,  C12Q1/68

    CPC classification number: C07K14/47 ,  C12Q1/6886 ,  C12Q2600/136

    Abstract: Objective methods for detecting and diagnosing prostate cancer (PRC) or prostatic intraepithelial neoplasia (PIN) are described herein. In one embodiment, the diagnostic method involves the determining a expression level of PRC -associated gene that discriminate between PRC or PIN and nomal cell. The present invention further provides methods of screening for therapeutic agents useful in the treatment of either or both of PRC and PIN, methods of treating either or both of PRC and PIN and method of vaccinating a subject against either or both of PRC and PIN.

    Abstract translation: 本文描述了用于检测和诊断前列腺癌（PRC）或前列腺上皮内瘤变（PIN）的客观方法。 在一个实施方案中，诊断方法涉及确定区分PRC或PIN和正常细胞的PRC相关基因的表达水平。 本发明还提供筛选用于治疗PRC和PIN中的任一者或两者的治疗剂的方法，治疗PRC和PIN中的任一者或两者的方法以及针对PRC和PIN中的任一者或两者接种受试者的方法。

    METHOD FOR DIAGNOSING TESTICULAR SEMINOMAS
    52.
    发明申请
    METHOD FOR DIAGNOSING TESTICULAR SEMINOMAS 审中-公开
    用于诊断特征SEMNOMAS的方法

    公开(公告)号：WO2004031410A3

    公开(公告)日：2004-07-08

    申请号：PCT/JP0311711

    申请日：2003-09-12

    Applicant: ONCOTHERAPY SCIENCE INC ,  JAPAN AS REPRESENTED BY THE PR ,  NAKAMURA YUSUKE ,  KATAGIRI TOYOMASA

    Inventor： NAKAMURA YUSUKE ,  KATAGIRI TOYOMASA

    IPC: C12Q1/68

    CPC classification number: C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/158

    Abstract: Objective methods for detecting and diagnosing testicular seminoma (TS) are described herein. In one embodiment, the diagnostic method involves the determining a expression level of TS -associated gene that discriminate between TS and nomal cell. The present invention further provides methods of screening for therapeutic agents useful in the treatment of TS, methods of treating TS and method of vaccinating a subject against TS.

    Abstract translation: 本文描述了用于检测和诊断睾丸精原细胞瘤（TS）的客观方法。 在一个实施方案中，诊断方法涉及确定区分TS和正常细胞的TS相关基因的表达水平。 本发明进一步提供筛选用于治疗TS的治疗剂，治疗TS的方法和接种个体接种TS的方法的方法。

    GEN Y POLIPEPTIDO RELACIONADOS CON EL CANCER DE MAMA.
    54.
    发明专利
    GEN Y POLIPEPTIDO RELACIONADOS CON EL CANCER DE MAMA. 未知

    公开(公告)号：ES2364078T3

    公开(公告)日：2011-08-24

    申请号：ES06782210

    申请日：2006-07-26

    Applicant: ONCOTHERAPY SCIENCE INC

    Inventor： NAKAMURA YUSUKE ,  KATAGIRI TOYOMASA ,  NAKATSURU SHUICHI

    IPC: C12Q1/68 ,  C12N15/113

    Abstract: Un método in vitro de cribado en busca de un compuesto para el tratamiento o la prevención del cáncer de mama, y dicho método comprende las etapas de: (a) poner en contacto un compuesto de ensayo con un polipéptido seleccionado del grupo que consiste en: (1) un polipéptido que comprende la secuencia de aminoácidos de SEQ ID NO: 25; (2) un polipéptido que comprende la secuencia de aminoácidos de SEQ ID NO: 25 o una secuencia que tiene al menos una homología del 80% respecto de SEQ ID NO: 25; y (3) un polipéptido codificado por un polinucleótido que hibrida en condiciones rigurosas a un polinucleótido que consiste en la secuencia nucleotídica de SEQ ID NO: 24 ó 26, en el que el polipéptido tiene una actividad biológica equivalente a un polipéptido que consiste en la secuencia de aminoácidos de SEQ ID NO: 25; (b) detectar la actividad de unión entre el polipéptido y el compuesto de ensayo; y (c) seleccionar un compuesto que se une al polipéptido.

    GENES AND POLYPEPTIDES RELATING TO BREAST CANCERS
    58.
    发明专利
    GENES AND POLYPEPTIDES RELATING TO BREAST CANCERS 未知

    公开(公告)号：CA2660438A1

    公开(公告)日：2008-02-14

    申请号：CA2660438

    申请日：2007-08-10

    Applicant: ONCOTHERAPY SCIENCE INC

    Inventor： NAKATSURU SHUICHI ,  KATAGIRI TOYOMASA ,  NAKAMURA YUSUKE

    IPC: C07K14/43 ,  C12N15/12 ,  G01N33/00

    Abstract: The present application provides novel human genes A7322, whose expressio n is markedly elevated in breast cancer. The present application also provid es human genes F3374 whose expression is markedly elevated in breast cancer. These genes and polypeptides encoded thereby can be used, for example, in t he diagnosis of breast cancer, and as target molecules for developing drugs against breast cancer. The invention features methods of screening for modul ators of the kinase activity of PBK/TOPK. The invention further provides met hods of screening for agents to prevent or treat cancer, such as breast canc er.

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