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公开(公告)号：EP3180390A1
公开(公告)日：2017-06-21
申请号：EP15744854.9
申请日：2015-06-16
Applicant: Universität Linz , Biomed-Zet Life Science GmbH
Inventor： TEASDALE, Ian , WILFERT, Sandra , AIGNER, Tamara , ITURMENDI, Aiztiber , BRUEGGEMANN, Oliver , SCHROEDER, Klaus , OLAWALE, Gbenga , HILDNER, Florian , RIGAU DE LLOBET, Maria
CPC classification number: C08G79/025 , A61L27/18 , A61L27/52 , A61L27/56 , C08G79/02 , C08G2230/00 , C08J9/26 , C08J2201/0446 , C08J2205/10 , C08J2207/10 , C08J2385/02 , C08L85/02
Abstract: The invention relates to a polymer for tissue engineering composed of biodegradable polyphosphazenes with photopolymerizable side groups, wherein the side groups of the polyphosphazenes are exclusively formed of amino acids and/or amino acid derivatives, wherein said side groups are bound to the backbone of the polyphosphazene via the amino group of the amino acid, and comprising a spacer bound to the acid group having a carbon chain of length m which comprises a vinyl group at its free end, wherein m = 0 to 10.
Abstract translation: 本发明涉及用于组织工程的聚合物，其由具有可光聚合侧基的生物可降解聚磷腈组成，其中聚磷腈的侧基完全由氨基酸和/或氨基酸衍生物形成，其中所述侧基与聚磷腈的骨架结合 经由氨基酸的氨基基团并且包含与具有长度为m的碳链的酸基团结合的间隔基，所述间隔基团在其自由末端包含乙烯基，其中m = 0至10。
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公开(公告)号：EP2093256A3
公开(公告)日：2009-10-14
申请号：EP09004700.2
申请日：2006-07-28
Applicant: Carnegie Mellon University
Inventor： Campbell, Phil , Fisher, Gregory W. , Kumta, Prashant , Sipe, David M. , Smith, Jason , Weiss, Lee E.
CPC classification number: C09D11/30 , A61L27/225 , A61L27/50 , C08J3/24 , C08J5/18 , C08J9/0066 , C08J9/26 , C08J2201/024 , C08J2201/0446 , C08J2201/046 , C08J2207/10 , C08J2300/16 , C08J2389/00 , C08L5/00 , C08L89/00 , C09D7/65 , C09D11/08
Abstract: Compositions and methods for manufacturing polymers are disclosed. Compositions include novel plastics, including films and shaped forms comprising polymer matrices that are biologically compatible and biodegradable. Such plastics may comprise polymers derived from natural sources. Further, such plastics are useful in biological systems for wound repair, implants, stents, drug encapsulation and delivery, and other applications. The disclosed methods comprise mild manufacturing processes such that various additives, such as biologically active proteins, sugars, lipids, and the like may be incorporated into the polymer matrix without subsequent loss of bioactivity during processing. Additionally, methods of manufacture for controlling mechanical properties, such as elasticity, pliancy, and the porosity of such plastics are disclosed.
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公开(公告)号：EP1948722A2
公开(公告)日：2008-07-30
申请号：EP06804682.0
申请日：2006-11-06
Applicant: PPD Meditech
Inventor： MORRISSETTE, Daniel , CROTEAU, Patrick
CPC classification number: B32B5/145 , A61L27/18 , A61L27/48 , A61L27/56 , B32B5/22 , B32B27/00 , C08J9/26 , C08J2201/0446 , C08J2205/05 , C08J2371/12 , Y10T428/249953 , Y10T428/249981 , Y10T428/249991 , C08L71/00
Abstract: A method for fabricating a porous structure from a first material. The method comprises the acts of mixing the first material with a second material to form a mixture, the first material having a melting point which is lower than the second material, heating the mixture under pressure to a temperature between a melting point of the first material and a melting point of the second material, cooling the molten mixture until it hardens and removing the second material from the first material. The method may also include a subsequent annealing step. There is also described a material suitable for implant, illustratively vertebral or spinal implants, comprising a rigid biocompatible polymer such as PEEK comprising a plurality of interconnected pores. The polymer illustratively has a porosity of between 50% and 85% by volume and in a particular embodiment is able to withstand pressures of up to 20 MPa. The porous PEEK material may also have a minimum thickness in any dimension of one (1 ) inch.
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公开(公告)号：EP0532611B1
公开(公告)日：1996-04-03
申请号：EP91910979.3
申请日：1991-06-05
Applicant: Pharmacia AB (reg.number 556131-9608)
Inventor： EK, Bo, Ragnar , ERIKSSON, Kjell, Gunnar , NYQVIST, Per, Gustaf, Hakan , RAGNARSSON, Gert, Anders
CPC classification number: C08J9/26 , A61K9/1652 , A61K9/2054 , A61K9/2081 , C08B15/02 , C08J2201/0446 , C08J2301/02 , C08L1/02
Abstract: The invention discloses a process for the manufacture of porous cellulose particles, which have regular shape, and a capacity of sorbing 1.5-9 times of their own weight of water, a tap bulk density of less than 0.85 g/ml. The process for the manufacture of these porous cellulose matrices is performed by mechanically treatment of hydrolyzed cellulose in a wet stage. The cellulose matrices have preferable a size of at least 0.1 mm and a tap bulk density of 0.1-0.7 g/ml. A bioactive substance or bioactive substances could be sorbed, precipitated or sublimized into the porous structure of the matrices. The matrices can be admixed with drugs or drug containing granules in order to improve the tabletting and tablet properties and thereafter compressed. Drug loaded matrices can be used for direct compression of tablets.
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55.发明公开POROUS MATERIAL OF ULTRAHIGH MOLECULAR WEIGHT POLYETHYLENE AND PRODUCTION THEREOF 失效超高分子量聚异戊二烯的多孔材料及其生产
公开(公告)号：EP0556391A4
公开(公告)日：1993-09-22
申请号：EP91918934
申请日：1991-11-05
Applicant: KOMATSU LTD.
IPC: B29C45/00 , B29C45/46 , B29C45/70 , B29C45/76 , B29C67/20 , B29K23/00 , B29K105/04 , C08J9/24 , C08J9/26 , C08J9/22
CPC classification number: C08J9/26 , B29C45/0001 , B29C67/205 , B29K2023/0683 , C08J9/24 , C08J2201/0446 , C08J2323/06
Abstract: A porous material of ultrahigh molecular weight polyethylene containing numerous interconnected pores, having permeability and being useful as filters, carriers and so forth; and a process for effectively producing said material. This material comprises minute particles of plasticized ultrahigh molecular weight polyethylene fused with one another so as to form interconnected pores communicating with the outer atmosphere. It is produced by injecting the plasticized ultrahigh molecular weight polyethylene into the cavity of a mold at a shear rate of 5 x 104 sec-1 or above and filling therein in such a manner that the ratio of G¿0? to V0 will be 0.7 g/cm?3¿ or less, wherein G¿0? represents product weight (g) and V0 represents product volume (cm?3¿).
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Patent Agency Ranking
公开(公告)号：US12104035B2
公开(公告)日：2024-10-01
申请号：US18223795
申请日：2023-07-19
Applicant: Bridgestone Sports Co., Ltd.
Inventor： Katsunobu Mochizuki
CPC classification number: C08J9/26 , A63B37/0024 , A63B37/0094 , C08J2201/0446 , C08J2375/08
Abstract: A foam composition that includes a polymer material such as polyurethane or polyurea and a leachable water-soluble fine powder is provided. This composition can be used in a relatively simple process to obtain a foam body (porous body) that is uniform only at the surface or uniform throughout. The foam body can be suitably used as a golf ball member in golf balls required to have good controllability on approach shots. Also provided is a method for producing a foam member, which method includes the steps of molding the foam composition to obtain a solid molded body, and then leaching out and removing the water-soluble fine powder so as to obtain a foam-molded body.
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公开(公告)号：US09764502B2
公开(公告)日：2017-09-19
申请号：US15348323
申请日：2016-11-10
Applicant: Vertera, Inc.
Inventor： Wei-Hsiang Chang , Stephen Lee Laffoon , Christopher S. D. Lee
CPC classification number: B29C43/04 , B29C33/00 , B29C44/58 , B29C67/202 , B29K2071/00 , B29L2031/753 , B29L2031/7532 , C08J9/26 , C08J2201/0446 , C08J2205/05 , C08J2300/22 , C08J2371/00
Abstract: In general, in various embodiments, the present disclosure is directed systems and methods for producing a porous surface from a solid piece of polymer. In particular, the present disclosure is directed to systems that include a track assembly, mold assembly, press assembly, and methods for using the same for producing a porous surface from a solid piece of polymer. In some embodiments, the present systems and methods are directed to processing a polymer at a temperature below a melting point of the polymer to produce a solid piece of polymer with an integrated a porous surface.
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公开(公告)号：US20170202511A1
公开(公告)日：2017-07-20
申请号：US15479541
申请日：2017-04-05
Applicant: Vertera, Inc.
Inventor： Wei-Hsiang CHANG , Stephen Lee LAFFOON , Christopher S.D. LEE , David Lee SAFRANSKI
CPC classification number: A61B5/4851 , A61B6/12 , A61B90/39 , A61B2090/392 , A61B2090/3966 , A61B2090/397 , A61F2/0077 , A61F2/44 , A61F2002/0081 , A61F2002/0086 , A61F2002/30011 , A61F2002/3092 , A61F2002/3093 , A61F2002/30971 , A61F2210/0071 , A61F2250/0098 , B29C67/202 , B29K2071/00 , B29L2031/753 , B29L2031/7546 , C08J9/0085 , C08J9/26 , C08J2201/0446 , C08J2371/00 , A61L27/18 , C08L71/00
Abstract: A method for making a polymer with a porous layer from a solid piece of polymer is disclosed. In various embodiments, the method includes heating a surface of a solid piece of polymer to a processing temperature and holding the processing temperature while displacing a porogen layer through the surface of the polymer to create a matrix layer of the solid polymer body comprising the polymer and the porogen layer. In at least one embodiment, the method also includes removing at least a portion of the layer of porogen from the matrix layer to create a porous layer of the solid piece of polymer.
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公开(公告)号：US20170071718A1
公开(公告)日：2017-03-16
申请号：US15362223
申请日：2016-11-28
Applicant: Vertera, Inc.
Inventor： Wei-Hsiang CHANG , Stephen Lee LAFFOON , Christopher S.D. LEE , David Lee SAFRANSKI
IPC: A61F2/00 , A61B6/00 , A61F2/44 , B29C44/34 , A61L27/56 , A61L27/50 , C08J9/26 , B29C44/04 , A61B90/00 , A61L27/18
CPC classification number: A61F2/0077 , A61B6/12 , A61B6/50 , A61B90/39 , A61B2090/3966 , A61F2/44 , A61F2002/0081 , A61F2002/0086 , A61F2210/0071 , A61F2250/0098 , A61L27/18 , A61L27/50 , A61L27/56 , A61L31/06 , A61L2430/38 , B29C44/0461 , B29C44/3415 , B29C67/202 , B29K2071/00 , B29L2031/753 , B29L2031/7546 , C08J9/0085 , C08J9/26 , C08J2201/0446 , C08J2371/00 , C08L71/00
Abstract: A method for making a polymer with a porous layer from a solid piece of polymer is disclosed. In various embodiments, the method includes heating a surface of a solid piece of polymer to a processing temperature and holding the processing temperature while displacing a porogen layer through the surface of the polymer to create a matrix layer of the solid polymer body comprising the polymer and the porogen layer. In at least one embodiment, the method also includes removing at least a portion of the layer of porogen from the matrix layer to create a porous layer of the solid piece of polymer.
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公开(公告)号：US20170057128A1
公开(公告)日：2017-03-02
申请号：US15348323
申请日：2016-11-10
Applicant: Vertera, Inc.
Inventor： Wei-Hsiang Chang , Stephen Lee Laffoon , Christopher S.D. Lee
CPC classification number: B29C43/04 , B29C33/00 , B29C44/58 , B29C67/202 , B29K2071/00 , B29L2031/753 , B29L2031/7532 , C08J9/26 , C08J2201/0446 , C08J2205/05 , C08J2300/22 , C08J2371/00
Abstract: In general, in various embodiments, the present disclosure is directed systems and methods for producing a porous surface from a solid piece of polymer. In particular, the present disclosure is directed to systems that include a track assembly, mold assembly, press assembly, and methods for using the same for producing a porous surface from a solid piece of polymer. In some embodiments, the present systems and methods are directed to processing a polymer at a temperature below a melting point of the polymer to produce a solid piece of polymer with an integrated a porous surface.
Abstract translation: 通常，在各种实施例中，本公开是用于从固体聚合物片制造多孔表面的系统和方法。 特别地，本公开涉及包括轨道组件，模具组件，压力组件以及用于使用该组件从固体聚合物块制造多孔表面的方法的系统。 在一些实施方案中，本发明的系统和方法涉及在低于聚合物熔点的温度下加工聚合物以产生具有整体多孔表面的聚合物固体片。
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