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    Method and device for monitoring the condition of a medium
    51.
    发明申请
    Method and device for monitoring the condition of a medium 审中-公开
    用于监测介质状态的方法和装置

    公开(公告)号：US20100045989A1

    公开(公告)日：2010-02-25

    申请号：US12311037

    申请日：2007-09-17

    Applicant: Jarmo Vanhanen ,  Marcus Rinkiö ,  Paivi Törmä ,  Jouko Korppi-Tommola ,  Kari Loberg ,  Jukka Elfström

    Inventor： Jarmo Vanhanen ,  Marcus Rinkiö ,  Paivi Törmä ,  Jouko Korppi-Tommola ,  Kari Loberg ,  Jukka Elfström

    IPC: G01N21/00

    CPC classification number: G01N21/8507 ,  G01N21/15 ,  G01N33/2888 ,  G01N2201/0662

    Abstract: The invention relates to a method for monitoring the condition of a medium in a channel, based on the transmission/emission of light, in which a light at a set wavelength is conducted through a medium layer defined by a measuring gap in a measuring head pushed in from an opening in the wall of the channel the intensity of the light passed through medium layer, or a variable proportional to it is measured, and the condition of the medium is evaluated, using measuring electronics, from the change of the intensity, according to established criteria. In the method, the wavelength of light used is such that the resolution of the aging phenomenon of the medium being monitored is optimal and the relationship of the temperature dependence of the medium to the measuring variable is taken into account. In addition, the invention also relates to a corresponding device.

    Abstract translation: 本发明涉及一种基于光的透射/发射来监视通道中的介质的状态的方法，其中设定波长的光通过由推动的测量头中的测量间隙限定的介质层传导 从通道壁的开口处，测量通过介质层的光的强度或与其成比例的变量，并且使用测量电子学根据强度的变化来评估介质的状态，根据 建立标准。 在该方法中，使用的光的波长使得被监测的介质的老化现象的分辨率是最佳的，并且考虑介质与测量变量的温度依赖性的关系。 此外，本发明还涉及相应的装置。

    OPTICAL ABSORPTION GAS ANALYSER
    52.
    发明申请
    OPTICAL ABSORPTION GAS ANALYSER 有权
    光学吸收气体分析仪

    公开(公告)号：US20090268204A1

    公开(公告)日：2009-10-29

    申请号：US12109254

    申请日：2008-04-24

    Applicant: Michael Tkachuk

    Inventor： Michael Tkachuk

    IPC: G01N21/00

    CPC classification number: G01N21/3504 ,  G01N2201/0662 ,  G01N2201/0668

    Abstract: An optical absorption gas analyser for determining the concentration of a target gas in a sample is disclosed. The analyser comprises a chamber for containing the sample in use; a radiation source assembly arranged to emit radiation into the chamber; a first radiation detector assembly arranged to detect radiation transmitted along a first optical path through the chamber and a second radiation detector assembly arranged to detect radiation transmitted along a second optical path through the chamber, wherein the length of the second optical path which the sample can intercept is shorter than that of the first optical path. The analyser further comprises a processor adapted to generate a sensing signal SS based on the detected radiation transmitted along the first optical path and a reference signal SR based on the detected radiation transmitted along the second optical path. The processor determines the concentration of the target gas in the sample based on a comparison of the sensing signal with the reference signal.

    Abstract translation: 公开了一种用于测定样品中目标气体浓度的光吸收气体分析仪。 分析仪包括用于容纳使用中的样品的室; 辐射源组件，被布置成将辐射发射到所述腔室中; 第一辐射检测器组件，被布置成检测沿着通过所述室的第一光路传输的辐射;以及第二辐射检测器组件，其布置成检测沿着通过所述室的第二光路传输的辐射，其中所述样品可以 截距比第一光路的截距短。 分析器还包括处理器，其适于基于沿着第一光路传输的检测到的辐射和基于沿着第二光路传输的检测到的辐射的参考信号SR生成感测信号SS。 处理器基于感测信号与参考信号的比较来确定样品中目标气体的浓度。

    Spectroscopic method and apparatus for measuring sugar concentrations
    53.
    发明授权
    Spectroscopic method and apparatus for measuring sugar concentrations 失效
    用于测量糖浓度的光谱法和仪器

    公开(公告)号：US4883953A

    公开(公告)日：1989-11-28

    申请号：US267109

    申请日：1988-11-01

    Applicant: Katsue Koashi ,  Hiroshi Yokota

    Inventor： Katsue Koashi ,  Hiroshi Yokota

    IPC: G01N21/35 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/31 ,  G01N21/359 ,  G01N21/49

    CPC classification number: A61B5/1455 ,  A61B5/14532 ,  G01N21/49 ,  G01N2021/1782 ,  G01N2021/3144 ,  G01N2021/3148 ,  G01N2021/4709 ,  G01N21/359 ,  G01N2201/065 ,  G01N2201/0662 ,  G01N2201/069 ,  Y10S250/91

    Abstract: This disclosure relates to a method for measuring the concentrations of sugars in liquids by the use of near infrared as well as an apparatus for practicing said method.The method comprises a step wherein the absorption spectrum of the sugar under investigation existing at a first depth relatively close to the surface in a sample is computed by using relatively weak power of near infrared, a step wherein the absorption spectrum of the sugar under investigation existing at a relatively deep second depth in the sample is computed by using relatively strong power of infrared, and a step wherein the concentration of the sugar under investigation in the sample is determined by computing the absorption spectrum of the sugar at a different depth between said first and second depths on the basis of the results of measurement in said first and second steps. The wavelengths for the use for said absorption spectrum are selected from anyone of wavelength bands of 950-1,150 nm, 1,150-1,300 nm, and 1,300-1,450 nm.Since, according to this method, wavelengths which are shorter and closer to the visible region than in the prior art are used, the method enables the measuring light beams to penetrate deeper in a living tissue and makes it possible to measure the concentrations of sugars existing in a deeper region non-invasively.

    SENSING OF COMPONENTS IN LIQUIDS
    54.
    发明授权
    SENSING OF COMPONENTS IN LIQUIDS 有权

    公开(公告)号：EP3074129B1

    公开(公告)日：2018-01-10

    申请号：EP14800099

    申请日：2014-11-21

    Applicant: UNIV GENT ,  IMEC VZW

    Inventor： BAETS ROELAND ,  RYCKEBOER EVA

    IPC: A61B5/145 ,  B01L3/00

    CPC classification number: A61B5/14532 ,  A61B5/14503 ,  A61B5/1459 ,  A61B5/150022 ,  A61B5/157 ,  A61B2562/04 ,  B01L3/5027 ,  G01N21/03 ,  G01N21/274 ,  G01N2201/0662

    Abstract: A sensing system and method for sensing a component in a liquid is disclosed. The system comprises a microfluidic channel, the microfluidic channel comprising a first end and a second end, wherein the microfluidic channel is open at the first end and closed at the second end. The system also comprises at least one measurement sensor positioned adjacent the first end, the measurement sensor being arranged for detecting a measurement signal and a reference sensor positioned in the microfluidic channel adjacent the second end, the reference sensor being arranged for detecting a reference signal of the liquid. The system further is configured for combining the measurement signal and the reference signal so as to filter out background influences.

    COUNTING COMPARTMENT AND METHOD FOR SAMPLE ANALYSIS
    55.
    发明公开
    COUNTING COMPARTMENT AND METHOD FOR SAMPLE ANALYSIS 审中-公开
    计数分区和样本分析方法

    公开(公告)号：EP3199937A1

    公开(公告)日：2017-08-02

    申请号：EP16153189.2

    申请日：2016-01-28

    Applicant: Minitüb GmbH

    Inventor： Wippenbeck, Georg ,  Simmet, Christian

    IPC: G01N15/06 ,  G01N21/03 ,  B01L3/00 ,  G02B21/26

    CPC classification number: G01N15/06 ,  B01L3/502715 ,  B01L2200/0647 ,  B01L2300/0816 ,  B01L2300/0851 ,  B01L2300/0854 ,  B01L2300/0877 ,  G01N21/0303 ,  G01N2015/0693 ,  G01N2015/1486 ,  G01N2021/0321 ,  G01N2021/0382 ,  G01N2021/0389 ,  G01N2201/066 ,  G01N2201/0662 ,  G02B21/26

    Abstract: The present invention relates to a counting compartment or counting chamber for analyzing samples comprising cells or particles, said counting compartment or chamber comprising at least two different depths provided by the bottom and top measurement window. The present invention further relates to a counting device comprising the counting compartment or counting chamber of the present invention. The present invention further relates to a method for analyzing samples comprising cells or particles, comprising the step of determining the difference between the value measured at the at least two different depths of a counting compartment or counting chamber. The present invention further relates to a method for analyzing samples comprising cells or particles, comprising the step of controlling the depth of a counting compartment.

    Abstract translation: 本发明涉及用于分析包含细胞或颗粒的样本的计数室或计数室，所述计数室或室包括由底部和顶部测量窗提供的至少两个不同深度。 本发明还涉及包括本发明的计数室或计数室的计数装置。 本发明进一步涉及分析包含细胞或颗粒的样品的方法，包括确定在计数室或计数室的至少两个不同深度处测量的值之间的差异的步骤。 本发明进一步涉及分析包含细胞或颗粒的样品的方法，包括控制计数隔室深度的步骤。

    Method and apparatus for noninvasively measuring a concentration of a blood component
    57.
    发明公开
    Method and apparatus for noninvasively measuring a concentration of a blood component 有权
    Gerätzur nichtinvasiven Konzentrationsmessung einer Blutkomponente

    公开(公告)号：EP1459679A1

    公开(公告)日：2004-09-22

    申请号：EP04251608.8

    申请日：2004-03-19

    Applicant: Samsung Electronics Co., Ltd.

    Inventor： Jeon, Kye-jin ,  Hwang, In-duk ,  Yoon, Gil-won ,  Han, Sang-joon

    IPC: A61B5/00 ,  G01N21/35

    CPC classification number: A61B5/14532 ,  A61B5/0053 ,  A61B5/107 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B2560/0223 ,  G01N21/359 ,  G01N2021/036 ,  G01N2021/3144 ,  G01N2201/0662

    Abstract: In an apparatus and method of noninvasively measuring a concentration of a blood component, the method includes (a) varying a thickness of a body part of a subject, measuring absorption spectrums at different thicknesses of the body part, obtaining a first differential absorption spectrum between the absorption spectrums measured at different thicknesses, actually measuring concentrations of the blood component, and establishing a statistical model using the first differential absorption spectrum and the actually measured concentrations; and (b) estimating the concentration of the blood component using a second differential absorption spectrum obtained with respect to the body part based on the statistical model.

    Abstract translation: 在非侵入性地测量血液成分浓度的装置和方法中，该方法包括：（a）改变被检体的身体部位的厚度，测量身体部位的不同厚度的吸收光谱，得到第一差分吸收光谱， 在不同厚度下测量的吸收光谱，实际测量血液成分的浓度，并使用第一个差示吸收光谱和实际测量的浓度建立统计模型; 和（b）基于统计模型使用相对于身体部位获得的第二差分吸收光谱来估计血液成分的浓度。

    Methods and apparatus for detecting microorganisms in blood culture vials
    58.
    发明公开
    Methods and apparatus for detecting microorganisms in blood culture vials 失效
    方法和装置用于检测在培养瓶中的微生物。

    公开(公告)号：EP0567230A3

    公开(公告)日：1995-04-26

    申请号：EP93302291.5

    申请日：1993-03-25

    Applicant: Becton Dickinson and Company

    Inventor： Berndt, Klaus W.

    IPC: C12M1/34 ,  G01N21/35

    CPC classification number: G01N21/274 ,  C12M41/46 ,  G01N21/3504 ,  G01N2021/5969 ,  G01N2201/06106 ,  G01N2201/066 ,  G01N2201/0662 ,  Y10S435/808

    Abstract: Methods and apparatus for detecting biological activity within a sample are disclosed. The present invention provides a combination of a first and a second infrared light source arranged on the side of a sample vial, and a first and a second narrow-band infrared detector similarly arranged on the side of the vial approximately opposite the sources. The disclosed arrangement cancels the sources of error while measuring the carbon dioxide content of the headspace gas above the sample. In operation, the present invention sequentially measures the photocurrents generated at each detector with no source turned on, with the first source turned on, and with the second source turned on and the first source turned off. The C0 2 absorption coefficient of the vial headspace gas is then calculated based on the photocurrents measured. This present invention allows compensation for source aging, detector aging, and vial wall thickness changes. Moreover, the present invention permits a determination of the absolute absorption coefficient at a selected wavelength, most preferably about 4.26 µm, which is the C0 2 absorption characteristic wavelength. The determination of the absolute C0 2 concentration within the headspace permits the detection of bacterial growth processes. Additionally, the disclosed source/detector combination can be produced at low cost. Thus, in preferred embodiments, the apparatus of the present invention comprises a plurality of vials that are simultaneously monitored by providing each of the plurality of vials with its own source/detector combination and activating and deactivating the sources and detectors using a multiplexer/demultiplexer arrangement.

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