公开(公告)号：WO2007084667A2

公开(公告)日：2007-07-26

申请号：PCT/US2007/001439

申请日：2007-01-18

Applicant: OSI PHARMACEUTICAL, INC. ,  ARNOLD, Lee, D. ,  CHEN, Xin ,  DONG, Hanping ,  GARTON, Andrew ,  MULVIHILL, Mark, Joseph ,  SMITH, Colin Peter, Sambrook ,  THOMAS, Gerard, Hugh ,  KRULLE, Thomas, Martin ,  WANG, Jing

Inventor： ARNOLD, Lee, D. ,  CHEN, Xin ,  DONG, Hanping ,  GARTON, Andrew ,  MULVIHILL, Mark, Joseph ,  SMITH, Colin Peter, Sambrook ,  THOMAS, Gerard, Hugh ,  KRULLE, Thomas, Martin ,  WANG, Jing

IPC: C07D471/04 ,  A61K31/437 ,  A61P35/00

CPC classification number: C07D471/04

Abstract: Compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , R 1 , and Q 1 are defined herein, inhibit kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer. The compounds are also useful in the treatment of inflammation, allergy, asthma, disease and conditions of the immune system, disease and conditions of the nervous system, cardiovascular diseases, disease and conditions of the eye, dermatological diseases, osteoporosis, diabetes, multiple sclerosis, and infections.

Abstract translation: 式（I）化合物及其药学上可接受的盐，其中X 1，X 2，X 3，X 4， X 1，X 5，X 6，X 7，R 1和Q 1 本文定义抑制激酶，并且可用于治疗和/或预防过度增殖性疾病如癌症。 该化合物还可用于治疗炎症，过敏，哮喘，免疫系统的疾病和状况，神经系统的疾病和状况，心血管疾病，眼睛疾病和病症，皮肤病，骨质疏松症，糖尿病，多发性硬化 和感染。

公开(公告)号：WO2005095387A1

公开(公告)日：2005-10-13

申请号：PCT/US2005/009900

申请日：2005-03-24

Applicant: ABBOTT LABORATORIES ,  MAKOTO, Aoyama ,  ARNOLD, Lee, D. ,  DINGES, Jürgen ,  DIXON, Richard, W. ,  DJURIC, Stevan, W. ,  ERICSSON, Anna, M. ,  FISCHER, Kimba ,  GASIECKI, Alan, F. ,  GRACIAS, Vijaya, J. ,  HOLMS, James, H. ,  MICHAELIDES, Michael, R. ,  MUCKEY, Melanie, A. ,  RAFFERTY, Paul ,  STEINMAN, Douglas, H. ,  WADA, Carol, K. ,  XIA, Zhiren ,  AKRITOPOULOU-ZANZE, Irini ,  ZHANG, Henry, Q.

Inventor： MAKOTO, Aoyama ,  ARNOLD, Lee, D. ,  DINGES, Jürgen ,  DIXON, Richard, W. ,  DJURIC, Stevan, W. ,  ERICSSON, Anna, M. ,  FISCHER, Kimba ,  GASIECKI, Alan, F. ,  GRACIAS, Vijaya, J. ,  HOLMS, James, H. ,  MICHAELIDES, Michael, R. ,  MUCKEY, Melanie, A. ,  RAFFERTY, Paul ,  STEINMAN, Douglas, H. ,  WADA, Carol, K. ,  XIA, Zhiren ,  AKRITOPOULOU-ZANZE, Irini ,  ZHANG, Henry, Q.

IPC: C07D409/04

CPC classification number: C07D471/04 ,  C07D231/54 ,  C07D409/04 ,  C07D409/14 ,  C07D413/14 ,  C07D495/04 ,  C07D495/14

Abstract: Compounds of the present invention are useful for inhibiting protein tyrosine kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Abstract translation: 本发明的化合物可用于抑制蛋白酪氨酸激酶。 还公开了制备化合物，含有化合物的组合物和使用该化合物的处理方法的方法。

公开(公告)号：US20180142862A1

公开(公告)日：2018-05-24

申请号：US15359080

申请日：2016-11-22

Applicant: Arnold Lee Hufstetler, III

Inventor： Arnold Lee Hufstetler, III

IPC: F21V1/02 ,  F21V9/16 ,  F21S6/00 ,  F21S8/06

CPC classification number: F21V1/02 ,  F21S6/005 ,  F21S8/063 ,  F21V1/12 ,  F21V9/30 ,  F21V11/02

Abstract: A louvre system for a conical lampshade includes three or more separate rings of varying inner diameter. The rings are structured to be placed over the top of the lampshade so that they become seated on an exterior of the lampshade in a horizontal position and at vertically spaced intervals to diffuse light and enhance the appearance of the lampshade. A method of the invention is directed to enhancing the appearance and light diffusing characteristics of a conical lampshade including the steps of: determining multiple ring positions on the lampshade at vertically spaced intervals; determining the exterior diameter of the lampshade at each ring position; providing at least three rings having inner diameters corresponding to the ring position diameters; and dropping the rings over the top of the lampshade in an order of largest to smallest inner ring diameter so that the rings become seated at the ring positions.

公开(公告)号：USD531053S1

公开(公告)日：2006-10-31

申请号：US29244240

申请日：2005-12-07

Applicant: Su-Yon McConville ,  Michael John Bolander ,  Joel James Kashuba ,  Jonathan Arnold Lee ,  Matthew Luke Prancuk ,  Javier Verdura

Designer： Su-Yon McConville ,  Michael John Bolander ,  Joel James Kashuba ,  Jonathan Arnold Lee ,  Matthew Luke Prancuk ,  Javier Verdura

公开(公告)号：USD530222S1

公开(公告)日：2006-10-17

申请号：US29244202

申请日：2005-12-07

Applicant: Su-Yon McConville ,  Michael John Bolander ,  Joel James Kashuba ,  Jonathan Arnold Lee ,  Jesse Pierce DelGigante ,  Javier Verdura

Designer： Su-Yon McConville ,  Michael John Bolander ,  Joel James Kashuba ,  Jonathan Arnold Lee ,  Jesse Pierce DelGigante ,  Javier Verdura

公开(公告)号：USD584614S1

公开(公告)日：2009-01-13

申请号：US29308612

申请日：2008-06-26

Applicant: Carrie Lynn Russell ,  Alexis Marie Schrimpf ,  Deanna Lynn DeBrosse ,  Donna Joy Wilson ,  Jonathan Arnold Lee

Designer： Carrie Lynn Russell ,  Alexis Marie Schrimpf ,  Deanna Lynn DeBrosse ,  Donna Joy Wilson ,  Jonathan Arnold Lee

公开(公告)号：USD574246S1

公开(公告)日：2008-08-05

申请号：US29254167

申请日：2006-02-17

Applicant: Carrie Lynn Russell ,  Alexis Marie Schrimpf ,  Deanna Lynn DeBrosse ,  Donna Joy Wilson ,  Jonathan Arnold Lee

Designer： Carrie Lynn Russell ,  Alexis Marie Schrimpf ,  Deanna Lynn DeBrosse ,  Donna Joy Wilson ,  Jonathan Arnold Lee

公开(公告)号：US06707392B1

公开(公告)日：2004-03-16

申请号：US10256460

申请日：2002-09-26

Applicant: Arnold Lee Melton

Inventor： Arnold Lee Melton

IPC: G08G100

CPC classification number: G08G1/052 ,  B60W2050/0064 ,  G07C5/008

Abstract: A system for controlling a speed of a vehicle is provided. The system includes a first communications unit and a second communications unit. The first communications unit is coupled to an engine controller for controlling an engine of a first vehicle. Also, the first communications unit includes a first sending unit for sending a first message to the engine controller. The second communications unit is located remotely from the first communications unit and includes a second sending unit for sending a second message to the first communications unit to cause the first communications unit to send the first message to control the speed of the first vehicle. A method for remotely controlling the speed of a vehicle is also included which includes sending a controlling message from a remote communications unit to a proximal communications unit coupled to an engine of a vehicle. The method further includes receiving a controlling message at the proximal communications unit and controlling a speed of the vehicle based on the message.

Abstract translation: 提供一种用于控制车辆速度的系统。 该系统包括第一通信单元和第二通信单元。 第一通信单元耦合到用于控制第一车辆的发动机的发动机控制器。 此外，第一通信单元包括用于向发动机控制器发送第一消息的第一发送单元。 第二通信单元远离第一通信单元定位，并且包括第二发送单元，用于向第一通信单元发送第二消息，以使第一通信单元发送第一消息以控制第一车辆的速度。 还包括用于远程控制车辆速度的方法，其包括将控制消息从远程通信单元发送到耦合到车辆的发动机的近端通信单元。 该方法还包括在近端通信单元处接收控制消息并且基于该消息来控制车辆的速度。

公开(公告)号：US5320011A

公开(公告)日：1994-06-14

申请号：US959211

申请日：1992-10-09

Applicant: Arnold Lee

Inventor： Arnold Lee

IPC: B26D7/22 ,  F16P3/00 ,  B26D1/30

CPC classification number: B26D7/22 ,  F16P3/00 ,  Y10T83/04 ,  Y10T83/8812

Abstract: A safety latch device for a paper cutter movably attached to the cutting arm of the paper cutter. The safety latch has a base catch, an arm catch and a trigger. The base catch engages with an extended portion of the base of the paper cutter to prevent a user from raising the cutting arm. The arm catch engages with a top surface of the cutting arm to prevent the safety latch from interfering with the cutting arm during operation. The trigger allows the user to disengage the base catch from the extended portion of the base so the cutting arm can be lifted.

Abstract translation: 一种用于可移动地连接到切纸机的切割臂的切纸机的安全闩锁装置。 安全闩具有底座，手臂扣和扳机。 基座卡扣与切纸器的基部的延伸部分啮合，以防止使用者抬起切割臂。 手臂卡扣与切割臂的上表面接合，以防止安全闩锁在操作过程中与切割臂发生干扰。 触发器允许使用者将基座卡扣与基座的延伸部分脱开，使得切割臂能够被提升。