-
公开(公告)号:US20150352512A1
公开(公告)日:2015-12-10
申请号:US14760416
申请日:2014-01-13
Applicant: DOUGLAS SCIENTIFIC
Inventor: Mark Whalen , Charles Gervais , Anthony Sanborn , Andrew Haug , Darren Cook , Satish Rai , Hans A. Mische , Stephen A. Judice , Daniel J. Shaffer
CPC classification number: B01J19/0046 , B01J2219/00313 , B01J2219/00351 , B01J2219/00495 , B01J2219/00585 , B01J2219/00722 , B01L7/00 , B01L2200/142 , B01L2300/0812 , B01L2300/1822 , B01L2300/1894 , C12Q1/6846 , G01N21/6456 , G01N35/00009 , G01N2035/00356 , G01N2035/0403 , G01N2035/1034
Abstract: A method for processing a biological material sample includes dispensing a sample into wells of an array tape from a sample plate, dispensing a reagent into the wells of the array tape from a reagent plate, and sealing the sample and the reagent in the array tape. The method further includes cooling the array tape and detecting biological material in the wells of the array tape.
Abstract translation: 一种用于处理生物材料样品的方法包括从样品板将样品分配到阵列带的孔中,从试剂板将试剂分配到阵列带的孔中,并将样品和试剂密封在阵列带中。 该方法还包括冷却阵列带并检测阵列带的孔中的生物材料。
-
公开(公告)号:US20220260603A1
公开(公告)日:2022-08-18
申请号:US17630471
申请日:2020-07-23
Applicant: DOUGLAS SCIENTIFIC, LLC
Inventor: Nathan Luther Westad , Andrew Richard Haug
Abstract: A controller configured to control one or more of aspiration and dispensing of a primary fluid by an aspirate-dispense apparatus, the aspirate-dispense apparatus comprising a secondary fluid in working communication with the primary fluid, wherein the controller is configured to: receive measurement signalling for a monitored flow parameter of the secondary fluid; determine, using calibration data, a volume of aspirated or dispensed primary fluid based on the received measurement signalling, the calibration data defining a relationship between the volume of aspirated or dispensed primary fluid and the monitored flow parameter of the secondary fluid; and control the flow of primary or secondary fluid based on the determined volume to aspirate or dispense a specific volume of primary fluid.
-
公开(公告)号:US10605657B2
公开(公告)日:2020-03-31
申请号:US15925453
申请日:2018-03-19
Applicant: DOUGLAS SCIENTIFIC, LLC
Inventor: Adnanul Haq , Richard J. Schoeneck
Abstract: Some embodiments include a scanning module with an optical reader coupled to a moveable carriage configured to move the optical reader in a first direction. In some embodiments, the optical reader includes excitation sources, emission detectors, emission energy conditioning elements, and a tape drive configured and arranged to selectively advance a tape in a second direction which is substantially perpendicular to the first direction. Further, some embodiments include a bar code reading station positioned adjacent to the moveable carriage. Other embodiments include an objective lens.
-
公开(公告)号:US10518267B2
公开(公告)日:2019-12-31
申请号:US15579887
申请日:2016-06-06
Applicant: DOUGLAS SCIENTIFIC, LLC
Inventor: Robert Hjelseth , Cory Hodgson , Andrew Bristow , Mark Baumgartner , David Sellnow , Cassie Keppel , John Steckelberg , Paul Newman
Abstract: Embodiments of the invention provide a filter kit including filters for processing a biological sample. Some embodiments include a filter cap in a tube kit with a first tube containing a buffer solution and a second tube containing a lyophilized master mix. Some embodiments include a method of processing a sample using the kit including mixing a biological sample in a first tube with the buffer solution, positioning the filter cap in the first tube, positioning a second tube on the filter cap, flipping the first tube, the filter cap, and the second cap to filter the biological sample and buffer solution mixture with the filter cap as it flows from the first tube to the second tube. Some embodiments include structure enabling transfer of materials through inline flow between the tubes. Some further embodiments include integrated structure for sample pulverization with integrated buffer and lyophilized master mix.
-
公开(公告)号:US20180245975A1
公开(公告)日:2018-08-30
申请号:US15925453
申请日:2018-03-19
Applicant: DOUGLAS SCIENTIFIC, LLC
Inventor: Adnanul Haq , Richard J. Schoeneck
CPC classification number: G01J1/58 , G01J3/10 , G01J3/4406 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
Abstract: Some embodiments include a scanning module with an optical reader coupled to a moveable carriage configured to move the optical reader in a first direction. In some embodiments, the optical reader includes excitation sources, emission detectors, emission energy conditioning elements, and a tape drive configured and arranged to selectively advance a tape in a second direction which is substantially perpendicular to the first direction. Further, some embodiments include a bar code reading station positioned adjacent to the moveable carriage. Other embodiments include an objective lens.
-
公开(公告)号:US09921101B2
公开(公告)日:2018-03-20
申请号:US14309435
申请日:2014-06-19
Applicant: Douglas Scientific, LLC
Inventor: Adnanul Haq , Richard J. Schoeneck
CPC classification number: G01J1/58 , G01J3/10 , G01J3/4406 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
Abstract: A scanning photometer and attendant methods are provided. The scanning photometer is generally characterized by first and second fluorophore excitation sources, an objective lens, and a common emission detector for the detection of first and second fluorophore emission originating from the excitation of the fluorophores via passage of excitation energy, via an optical path of the objective lens, from the excitation sources. Excitation energy and emission energy conditioning elements are likewise provided, operatively interposed before or after the objective lens as the case may be.
-
公开(公告)号:US20170028399A1
公开(公告)日:2017-02-02
申请号:US15290912
申请日:2016-10-11
Applicant: DOUGLAS SCIENTIFIC, LLC
Inventor: BRUCE PETERSON , Brent Urke
CPC classification number: B01L3/5085 , B01L3/50855 , B01L3/545 , B01L9/523 , B01L2200/025 , B01L2300/021 , B01L2300/0829 , B01L2300/0858 , B01L2300/123 , G01N35/00009
Abstract: A tape adaptor (8) includes a bottom plate (20) and a top plate (60) mounted to the bottom plate (20) with a space (40) defined between an upper side wall (26) of the bottom plate (20) and a lower face (68) of the top plate (60) for receiving a tape segment (100) remaining on or cut from a continuous array tape (10). The tape segment (100) includes an array of wells (54) between two edges (52). A slit (46) is formed between an end (62) of the top plate (60) and an end (22) of the bottom plate (20). The tape segment (100) is slideably extended through the slit (46) into the space (40) with the edges (52) sliding on two ridges (38) on two longitudinal edges (36) of the bottom plate (20). The bottom plate (20) can include at least one groove (30) to receive the array of wells (54) of the tape segment (100). The tape segment (100) is positioned relative to the tape adaptor (8) by the ridges (38) or the groove (30).
Abstract translation: 磁带适配器(8)包括底板(20)和安装到底板(20)的顶板(60),其中限定在底板(20)的上侧壁(26)之间的空间(40) 和顶板(60)的下表面(68),用于接纳残留在连续阵列带(10)上或从连续阵列带(10)切割的带段(100)。 带段(100)包括位于两个边缘(52)之间的孔阵列(54)。 在顶板(60)的端部(62)和底板(20)的端部(22)之间形成狭缝(46)。 所述带段(100)通过所述狭缝(46)可滑动地延伸到所述空间(40)中,所述边缘(52)在所述底板(20)的两个纵向边缘(36)上的两个脊(38)上滑动。 底板(20)可以包括至少一个凹槽(30),以容纳带段(100)的孔阵列(54)。 带段(100)通过脊(38)或槽(30)相对于带适配器(8)定位。
-
公开(公告)号:US08759795B2
公开(公告)日:2014-06-24
申请号:US13942135
申请日:2013-07-15
Applicant: Douglas Scientific, LLC.
Inventor: Adnanul Haq , Richard J. Schoeneck
CPC classification number: G01J1/58 , G01J3/10 , G01J3/4406 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
Abstract: A scanning photometer and attendant methods are provided. The scanning photometer is generally characterized by first and second fluorophore excitation sources, an objective lens, and a common emission detector for the detection of first and second fluorophore emission originating from the excitation of the fluorophores via passage of excitation energy, via an optical path of the objective lens, from the excitation sources. Excitation energy and emission energy conditioning elements are likewise provided, operatively interposed before or after the objective lens as the case may be.
Abstract translation: 提供了扫描光度计和附带的方法。 扫描光度计通常的特征在于第一和第二荧光团激发源,物镜和共同的发射检测器,用于通过激发能量经由经由激发能量的激发来检测源自荧光团的激发的第一和第二荧光团发射, 物镜,来自激发源。 激光能量和发射能量调节元件同样被提供,可操作地插入物镜之前或之后(视情况而定)。
-
-
-
-
-
-
-