Abstract:
Systems and methods for synthesizing molecules on a substrate surface are disclosed. In one aspect, a molecule synthesizing system (100) includes a crossbar array (102) with a planar arrangement of crossbar junctions. Each crossbar junction is independently switchable between a high-resistance state and a low-resistance state. The system also includes a slab (104) with a first surface (114) and a second surface (116) parallel to the first surface. The second surface is disposed on the crossbar array. A current applied to a crossbar junction in a high-resistance state creates an adjacent heated site on the first surface for attaching thermally reactive molecules for molecular synthesis.
Abstract:
A metallic-nanofinger device (101) for chemical sensing. The device (101) includes a substrate (110), and a plurality (120) of nanofingers. A nanofinger (120-1) includes a flexible column (120-1A), and a metallic cap (120-1B) coupled to an apex (120-1C) of the flexible column (120-1A). At least the nanofinger (120-1) and a second nanofinger (120-2) are to self-arrange into a close-packed configuration with at least one analyte molecule (220-1) disposed between at least the metallic cap (120-1B) and a second metallic cap (120-2B) of respective nanofinger (120-1) and second nanofinger (120-2). A morphology of the metallic cap (120-1B) is to generate a shifted plasmonic-resonance peak (622) associated with amplified luminescence from the analyte molecule (220-1). A coating (120-1D) encapsulating the metallic cap (120-1B) to respond upon exposure to a liquid (212), and a chemical-sensing chip (701) including the metallic-nanofinger device (101) are also provided.
Abstract:
An ionic device includes a layer (220) of an ionic conductor containing first and second species (222, 224) of impurities. The first species (222) of impurity in the layer (220) is mobile in the ionic conductor, and a concentration profile of the first species (222) determines a functional characteristic of the device (200). The second species (224) of impurity in the layer (220) interacts with the first species (222) within the layer (220) to create a structure (226) that limits mobility of the first species (222) in the layer (220).
Abstract:
A multi-pillar structure for molecular analysis is provided. The structure comprises at least two nanopoles, each nanopole attached at one end to a substrate and freely movable along its length. The opposite ends of the at least two nanopoles are each capable of movement toward each other to trap at least one analyte molecule at their opposite ends. Each nanopole is coated with a metal coating. An array of such multi-pillar structures is also provided. A method for preparing the multi-pillar structure is further provided.
Abstract:
A self-collecting substrate (10) for surface enhanced Raman spectroscopy having a first surface (10a) and a second surface (10b) opposed thereto, comprising: a waveguiding layer (10') supported on a support layer (10"), with the waveguiding layer associated with the first surface and the support layer associated with the second surface; and a plurality of metal nano-antennae (14) established on the first surface and operatively associated with the plurality of openings such that exposure of analyte (18) to the light causes preferential aggregation of the analytes in the vicinity of the nano-antennae. A system (50) for at least one of attracting the analytes 18) to the metal nano-antennae (14) and performing surface enhanced Raman spectroscopy using the substrate (10) and a method for increasing a signal for surface enhanced Raman spectroscopy are provided.
Abstract:
A light amplifying structure (100) for Raman spectroscopy includes a resonant cavity (108). A distance between a first portion (102B) and a second portion (102A) of the structure (100) forming the resonant (cavity (108) is used to amplify excitation light emitted from a light source (420) into the resonant cavity (108) at a first resonant frequency of the resonant cavity (108). Also, the resonant cavity (108) amplifies radiated light radiated from a predetermined molecule excited by the excitation light in the resonant cavity at a second resonant frequency of the resonant cavity (108).
Abstract:
Broad band structures (10, 10', 10") for surface enhanced Raman spectroscopy are disclosed herein. Each embodiment of the structure (10, 10', 10") is made up of a metal layer, and a dielectric layer (16A, 16S, 16P) established on at least a portion of the metal layer. The dielectric layer (16A, 16S, 16P) has a controlled thickness that varies from at least one portion of the dielectric layer (16A, 16s, 16p) to at least another portion of the dielectric layer. Nanostructures are established on the dielectric layer (16A, 16S, 16P) at least at the portion and the other portion, the nanostructures thus being configured to exhibit variable plasmon resonances.
Abstract:
Devices, systems, and methods for enhancing Raman spectroscopy and hyper-Raman are disclosed. A molecular analysis device (100', 100") for performing Raman spectroscopy comprises a substrate (110) and a laser source (120) disposed on the substrate (110). The laser source (120) may be configured for generating a laser radiation (125), which may irradiate an analyte (31 ) disposed on a Raman enhancement structure (300). The Raman enhancement structure (300) may be disposed in a waveguide (130). The molecular analysis device (100', 100") also includes a wavelength demultiplexer (240) and radiation sensors (290) disposed on the substrate (110) and configured for receiving a Raman scattered radiation (160), which may be generated by the irradiation of the analyte (310) and Raman enhancement structure (300).
Abstract:
An application having an associated and a graphical user interface is initiated. Thereafter, the widget determines a first state of the application. Once the first state of the application is determined, the widget calls at least one remote repository to retrieve one or more electronic annotations associated with the first state of the application. These electronic annotations are then displayed in connection with the graphical user interface of the application.