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公开(公告)号：US10436002B2
公开(公告)日：2019-10-08
申请号：US14433464
申请日：2013-09-23
Applicant: Texas Tech University System
Inventor： Mohamed Soliman , Mehdi Rafiee , Elias Pirayesh
Abstract: The present invention provides a method of hydraulically fracturing a well penetrating an subterranean formation by optimizing the spacing of fractures along a wellbore to form a complex network of hydraulically connected fractures by identifying a deviated wellbore in a subterranean formation; introducing a series of fractures in the deviated wellbore, wherein the series of fractures comprising at least a first fracture, a second fracture, a third fracture and a fourth fracture each separated by a non-uniformed and an increased spacing distance such that the spacing distance from each adjacent fracture in the series of fractures is at an increased distance; and forming one or more complex fractures extending from the series of fractures to form a complex fracture network.
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公开(公告)号：US20190274536A1
公开(公告)日：2019-09-12
申请号：US16294902
申请日：2019-03-06
Applicant: Texas Tech University System
Inventor： Behnam Askarian , Jo Woon Chong , Fatemehsadat Tabei
Abstract: Diagnostic tool for eye disease detection using a smartphone. At least some of the example embodiments are methods including capturing, by way of a camera lens on a device, an image of an eye to create a raw specimen; processing the raw specimen to create a processes specimen; performing edge detection on the processed specimen to detect a boundary of a cornea; extracting a region of interest of the cornea; identifying a boundary of the region of interest using a boundary tracing technique to identify a second boundary; analyzing the second boundary of the region of interest, by measuring a slope of the second boundary; and classifying the region of interest as including an eye disease, based on the analyzing the second boundary.
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公开(公告)号：US20190183905A1
公开(公告)日：2019-06-20
申请号：US16217752
申请日：2018-12-12
Applicant: Texas Tech University System
Inventor： John J. McGlone
IPC: A61K31/5685 , A61K31/568 , A61K31/47 , A61K47/10 , A61K47/44 , A61K9/00 , A61K9/12 , A61P15/08
CPC classification number: A61K31/5685 , A61K9/0043 , A61K9/122 , A61K31/47 , A61K31/568 , A61K47/10 , A61K47/44 , A61P15/08
Abstract: The present disclosure provides for pheromonal compositions and methods of using the compositions for stimulating early onset of estrus in a peri-pubertal suid and methods of improving performance of the peri-pubertal female suid. The composition may comprise at least one steroid hormone and a heterocyclic aromatic compound. The method comprises administering the pheromone composition to the suid for a period of time.
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公开(公告)号：US20190085679A1
公开(公告)日：2019-03-21
申请号：US16135585
申请日：2018-09-19
Applicant: Texas Tech University System
Inventor： Marshall Watson
Abstract: A system, method, and apparatus for separating liquid from gas in a horizontal well comprises a first tubing member comprising one of a screen-walled tube and a perforated tube, and a second tubing member configured inside the first tubing member, the second tubing member comprising a blank-walled tube section and one of a screen walled tube section and a perforated tube section, wherein the second tubing member has a smaller diameter than the first tubing member.
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公开(公告)号：US20190062469A1
公开(公告)日：2019-02-28
申请号：US16117073
申请日：2018-08-30
Applicant: Texas Tech University System
Inventor： Guillermo A. Altenberg , Hongjun Liang
Abstract: The present invention includes compositions, methods, and methods of making and using a polymer-encased nanodisc comprising: one or more integral membrane proteins in a lipid layer; and a polymer comprising zwitterionic styrene-maleic acid derivative repeating units that carry zero or nearly zero negative charge, and the polymer-encased nanodiscs.
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Patent Agency Ranking
公开(公告)号：US10107770B2
公开(公告)日：2018-10-23
申请号：US15319816
申请日：2015-06-18
Inventor： David Weindorf , Somsubhra Chakraborty
IPC: G01N23/22 , G01N33/24 , G01N21/3563 , G01N21/359 , G01N23/223 , G01N23/2206
Abstract: The present invention determines one or more properties of a soil sample by scanning a soil sample using a visible near infrared diffuse reflectance (VisNIR) spectroradiometer, scanning the soil sample using a x-ray fluorescence (PXRF) spectrometer, receiving a diffuse reflectance spectra from the VisNIR spectroradiometer and an elemental data from the PXRF spectrometer, determining one or more properties of the soil sample using one or more processors and a predictive model that relates the diffuse reflectance spectra and the elemental data to the one or more properties, and providing the one or more properties of the soil sample to one or more input/output interface.
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公开(公告)号：US20180112223A1
公开(公告)日：2018-04-26
申请号：US15838556
申请日：2017-12-12
Applicant: Texas Tech University System
Inventor： Mingtao Zeng , Maria T. Arevalo
IPC: C12N15/113 , C07K16/28
CPC classification number: C12N15/1138 , C07K16/28 , C07K2317/34 , C07K2317/76 , C12N2310/14 , C12N2320/30
Abstract: The present invention includes siRNAs and antibodies that block the interaction between TEM8 and/or CMG2 cell surface proteins and anthrax toxin and methods of treating anthrax exposure with the same.
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公开(公告)号：US09943502B2
公开(公告)日：2018-04-17
申请号：US15313339
申请日：2015-05-27
Applicant: Texas Tech University System
Inventor： Weimin Gao
IPC: A61K31/335 , A61K31/35 , A61K31/28 , A61K31/215 , A61K31/12 , A61K31/366 , A61K33/24 , C12Q1/68 , G01N33/574 , C12N15/113
CPC classification number: A61K31/366 , A61K31/12 , A61K31/222 , A61K31/282 , A61K31/352 , A61K31/4439 , A61K31/555 , A61K31/7105 , A61K33/24 , A61K45/06 , C12N15/113 , C12N2310/14 , C12N2310/531 , C12N2320/31 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N33/574 , G01N33/57423 , G01N33/57496 , G01N2333/47 , G01N2333/4748 , G01N2440/14 , A61K2300/00
Abstract: The present invention includes compositions and methods for the treatment of cancer comprising an antineoplastic drug and an inhibitor of chromosome maintenance region 1 (CRM1) protein expression or activity, wherein the inhibitor of CRM1 enhances the anti-neoplastic effect of the antineoplastic drug.
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69.发明申请公开(公告)号：US20180094300A1
公开(公告)日：2018-04-05
申请号：US15563838
申请日：2016-03-30
Applicant: Texas Tech University System
Inventor： Marie Bugarel , Kendra Nightingale , Guy Loneragan , Mindy M. Brashears
IPC: C12Q1/689 , C12Q1/6806 , C12Q1/686
CPC classification number: C12Q1/689 , C12Q1/6806 , C12Q1/686 , C12Q2600/158 , C12Q2600/16 , Y02A50/451
Abstract: The present invention provides a set of oligonucleotides to screen for the presence of targeted Salmonella serotypes in enrichment or to characterize presumptive colonies. The set of oligonucleotides includes at least one set of primers and probe for the detection of Salmonella serotype selected from Newport, Heidelberg, Infantis, and Hadar and to discriminate between. These new markers can be used after the initial screening assay described herein as a discrimination assay to differentiate S. Heidelberg from S. Infantis and S. Hadar from S. Newport.
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公开(公告)号：US20180092852A1
公开(公告)日：2018-04-05
申请号：US15725099
申请日：2017-10-04
Applicant: Texas Tech University System
Inventor： Harvinder Singh Gill , Shashwati U. Atwe , Pedro E. Gonzalez-Cruz
CPC classification number: A61K9/4816 , A61K9/1664 , A61K9/4858 , A61K9/5063 , A61K9/5068 , A61K36/00 , A61K38/00 , A61K39/00
Abstract: The present invention includes methods of making a hollow exine shell from pollen grains comprising the steps of: providing a plant pollen or spore; extracting organic matter from the plant pollen or spore with an organic solvent; after the organic extraction treating the plant pollen or spore with an acid solution; after the acid treatment treating the plant pollen or spore with an alkali solution; and isolating the plant pollen or spore, wherein the pollen or spore have open apertures on pollens with visible apertures that open to the interior hollow cavity, wherein the same apertures are closed in naturally occurring pollens.
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