公开(公告)号：DK2638175T3

公开(公告)日：2017-08-28

申请号：DK10790739

申请日：2010-11-09

Applicant: UNIVERSITA' DEGLI STUDI DI TRIESTE

Inventor： TONGIORGI ENRICO ,  VAGHI VALENTINA ,  VICARIO ANNALISA ,  BAJ GABRIELE

IPC: C12Q1/68 ,  G01N33/50 ,  G01N33/58

公开(公告)号：ITUB20159615A1

公开(公告)日：2017-06-29

申请号：ITUB20159615

申请日：2015-12-29

Applicant: UNIVERSITA’ DEGLI STUDI DI TRIESTE

Inventor： LONGO GIOVANNI ,  PELLEGRINO FELICE ANDREA ,  GIACOMINI CRISTIAN ,  FENU GIANFRANCO ,  ASSALONE ANDREA

IPC: G06T7/20

公开(公告)号：IT1391668B1

公开(公告)日：2012-01-17

申请号：ITPD20080219

申请日：2008-07-23

Applicant: UNIVERSITA' DEGLI STUDI DI TRIESTE

Inventor： PAOLETTI SERGIO ,  DONATI IVAN ,  MARSICH ELEONORA ,  TRAVAN ANDREA

IPC: C08B37/00 ,  C08L5/08

公开(公告)号：EP3909600A1

公开(公告)日：2021-11-17

申请号：EP20174045.3

申请日：2020-05-12

Applicant: International Centre For Genetic Engineering And Biotechnology - ICGEB ,  Universita Degli Studi di Trieste

Inventor： ZACCHIGNA, Serena ,  GIACCA, Mauro ,  CAPPELLETTO, Ambra

IPC: A61K38/39 ,  A61K48/00 ,  A61P35/00 ,  A61P35/04 ,  C07K14/78

Abstract: The present invention refers to the EMID2 protein or a nucleic acid coding thereof for use for the treatment of a tumor or for the treatment or prevention of metastasis.
Compositions, vectors and formulations for the administration of EMID2 or a nucleic acid coding thereof for the above mentioned uses are also within the scope of the invention.

公开(公告)号：EP3255420A3

公开(公告)日：2018-02-14

申请号：EP17175371.8

申请日：2017-06-09

Applicant: Universita' Degli Studi di Trieste

Inventor： Grassi, Gabriele ,  Grassi, Mario ,  Abrami, Michela

IPC: G01N24/00

Abstract: Method to carry out analyses on a sputum sample (11) comprising at least one component (C i ), that provides the following steps:
- making available said sputum sample (11);
- making available at least one set of reference data (14) associated with different microbial-based pulmonary pathological conditions;
- measuring at least a relaxation time of the hydrogen atoms (T 2i ) and an average relaxation time of the hydrogen atoms (T 2m );
- comparing said average relaxation time (T 2m ) and said relaxation times of the hydrogen atoms (T 2i ) with said reference data (14) in order to determine the pathological condition associated with said sputum sample (11);
- supplying information (17) correlated to the pathological condition associated with said sputum sample (11) and/or correlated to at least part of said components (C i ).

Abstract translation: 对包含至少一种组分（Ci）的痰样品（11）进行分析的方法，所述方法提供以下步骤： - 提供所述痰样品（11）; - 提供与不同的基于微生物的肺部病理状况相关的至少一组参考数据（14）; - - 至少测量氢原子的弛豫时间（T2i）和氢原子的平均弛豫时间（T2m）; - 将所述平均弛豫时间（T2m）和所述氢原子的弛豫时间（T2i）与所述参考数据（14）进行比较以确定与所述痰样品（11）相关的病理状况; - 提供与所述痰样品（11）相关的病理状况和/或与所述组分（Ci）的至少一部分相关的病理状况相关的信息（17）。

公开(公告)号：EP2419442B1

公开(公告)日：2016-11-16

申请号：EP10723778.6

申请日：2010-04-15

Applicant: Universita' Degli Studi Di Trieste

Inventor： BANDIERA, Antonella

IPC: A61L27/22 ,  C07K14/78 ,  A61K38/39 ,  A61L27/52

CPC classification number: C07K14/78 ,  A61L27/227 ,  A61L27/52

公开(公告)号：EP2649093B1

公开(公告)日：2016-08-10

申请号：EP11807881.5

申请日：2011-12-12

Applicant: Universita Degli Studi di Trieste

Inventor： EDOMI, Paolo ,  BEMBICH, Sara ,  CORTINI, Andrea

IPC: C07K14/47 ,  G01N33/564

CPC classification number: G01N33/6893 ,  C07K14/4702 ,  G01N33/564 ,  G01N2800/285 ,  G01N2800/52

公开(公告)号：EP2721178A1

公开(公告)日：2014-04-23

申请号：EP12738204.2

申请日：2012-06-15

Applicant: Universita' Degli Studi Di Trieste ,  University Of Dundee

Inventor： DEL SAL, Giannino ,  NAPOLI, Marco ,  GIRARDINI BROVELLI, Javier Enrique ,  PIAZZA, Silvano ,  THOMPSON, Alastair

IPC: C12Q1/68

CPC classification number: G01N33/57415 ,  C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158

Abstract: It is described the influence of the presence of mutations in the TP53 gene in association with high levels of the enzyme prolyl isomerase Pin1 and a molecular signature of 10 genes expression correlated with the expression of Pin1 and p53 for the prognosis of breast tumors. The association between overexpression of Pin1 and the presence of protein p53 mutants induces transcriptional programs which promote tumor aggressiveness and in a cohort of patients the overexpression of Pin1 has proved to influence the prognostic value of the presence of mutations in the gene TP53. The assessment of the expression of Pin1 in the presence of mutations of the gene TP53, together with the detection of the expression of the genes forming the molecular signature can therefore be used for the prognosis of breast cancer.

公开(公告)号：EP2638175A1

公开(公告)日：2013-09-18

申请号：EP10790739.6

申请日：2010-11-09

Applicant: Universita' Degli Studi di Trieste

Inventor： TONGIORGI, Enrico ,  VAGHI, Valentina ,  VICARIO, Annalisa ,  BAJ, Gabriele

IPC: C12Q1/68 ,  G01N33/50 ,  G01N33/58

CPC classification number: G01N33/5008 ,  C07K14/475

Abstract: The present invention concerns a method for the identification of specific compounds which modulate brain-derived neurotrophic factor, which can be used as drugs for the treatment of neurological and neuropsychiatric diseases and which are suitable for the treatment of deleterious effects caused to the nervous system by abuse of illegal or legal drugs.

公开(公告)号：EP2421922A1

公开(公告)日：2012-02-29

申请号：EP10723327.2

申请日：2010-04-22

Applicant: Universita' Degli Studi Di Trieste

Inventor： ADAMI, Gianpiero

IPC: C09D9/00

CPC classification number: C09D9/005

Abstract: The invention relates to a dimethylsulphoxide and limonene based paint stripping composition, preferably thickened by adding a thickener of cellulose type, and to a device for its application, formed from an absorbent layer in which the composition is included and a support layer. The device is suitable for a method of paint stripping by peeling.