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公开(公告)号：KR1020120009183A
公开(公告)日：2012-02-01
申请号：KR1020100071135
申请日：2010-07-23
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A composition containing Potulacae Grandiflorae Herba extract is provided to promote differentiation of human mesenchymal stem cells into adipocytes. CONSTITUTION: An external use skin composition for promoting differentiation of human mesenchymal stem cells into adipocytes contains 0.0001-30 wt% of Potulacae Grandiflorae Herba extract as an active ingredient. A pharmaceutical composition for promoting the differentiation contains the Potulacae Grandiflorae Herba extract as an active ingredient. The dose of the Potulacae Grandiflorae Herba extract is 0.001mg/kg-2000mg/kg per day.
Abstract translation: 目的：提供含有甘草提取物的组合物，以促进人间充质干细胞分化为脂肪细胞。 构成：用于促进人类间充质干细胞分化为脂肪细胞的外用皮肤组合物含有0.0001-30重量％的Pot草提取物作为活性成分。 用于促进分化的药物组合物含有大戟草作为活性成分。 Pot草提取物的剂量为0.001mg / kg-2000mg / kg /天。
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公开(公告)号：KR1020110118392A
公开(公告)日：2011-10-31
申请号：KR1020100037969
申请日：2010-04-23
Applicant: (주)아모레퍼시픽
IPC: A61K36/185 , A61K8/97 , A61K9/00 , C12N5/0775
CPC classification number: A61K36/185 , A61K8/97 , A61K9/0021 , C12N5/0663
Abstract: 본 발명은 인간 중간엽줄기세포의 지방세포로의 분화를 촉진하는 조성물에 관한 것으로, 보다 상세하게는 미후도 및 미후등 추출물 중 적어도 1종 이상을 유효성분으로 함유하여 인간 중간엽줄기세포를 지방세포로 분화하는 것을 촉진시킴으로써 지방체(Lipid droplet)를 생성하여 피부의 볼륨과 탄력을 증진시키고 주름을 개선시키는 조성물에 관한 것이다.
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公开(公告)号：KR101056278B1
公开(公告)日：2011-08-11
申请号：KR1020080073605
申请日：2008-07-28
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 피부 미용 또는 성형용 조성물에 관한 것으로서, 보다 상세하게는 관중(
Crassirhizomae
Rhizoma ), 오약(
Linderae
Radix ), 계피(
Cinnamomum
cassia ) 및 고삼(
Saphora flavescens ) 추출물로 이루어진 군에서 선택된 1종 이상을 유효성분으로 함유하여 사람의 중간엽줄기세포를 지방세포로 분화시키는 것을 촉진하는 피부 미용 또는 성형용 조성물에 관한 것이다.
관중, 오약, 계피, 고삼, 중간엽줄기세포 분화, 지방세포 생성Abstract translation: 皮肤化妆品或模塑组合物技术领域本发明涉及皮肤化妆品或模塑组合物，
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公开(公告)号：KR1020100037832A
公开(公告)日：2010-04-12
申请号：KR1020080097137
申请日：2008-10-02
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/447 , A61K2800/78 , A61Q19/00
Abstract: PURPOSE: A composition containing L-cystathionine, cystathionine or mixture thereof is provided to ensure excellent sliming effect through suppression of adipocyte differentiation. CONSTITUTION: A composition for sliming contains L-cystathionine, cystathionine or mixture thereof as an active ingredient. The composition suppresses adipocyte differentiation. The differentiation of adipocytes is differentiation of mesenchymal stem cells to adipocytes. The composition contains 0.0001-30 weight% of active ingredient based on total weight.
Abstract translation: 目的：提供含有L-胱硫醚，胱硫醚或其混合物的组合物以通过抑制脂肪细胞分化来确保优异的苗条效果。 构成：用于减肥的组合物含有L-胱硫醚，胱硫醚或其混合物作为活性成分。 该组合物抑制脂肪细胞分化。 脂肪细胞的分化是间充质干细胞向脂肪细胞的分化。 该组合物含有0.0001-30重量％的基于总重量的活性成分。
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公开(公告)号：KR1020100018278A
公开(公告)日：2010-02-17
申请号：KR1020080076976
申请日：2008-08-06
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/498 , A61K8/97 , A61K36/232 , A61Q19/08
Abstract: PURPOSE: A cosmetic or pharmaceutical composition containing decursin is provided to enhance the number of epidermal keratinocyte stem cells(KSC) and ensure anti-aging. CONSTITUTION: A composition for proliferating epidermal keratinocyte stem cells contains decursin as an active ingredient. The decursin is obtained from Angelica gigas Nakai ethanol extract or Angelica gigas Nakai supercritical extract. The Angelica gigas Nakai ethanol extract is obtained by adding ethanol, stirring and removing solvent. The Angelica gigas Nakai supercritical extract is obtained by preparing micro powder, and purifying using silica gel column chromatography. A cosmetic composition and a pharmaceutical composition for anti-aging contain a composition containing decursin as an active ingredient.
Abstract translation: 目的：提供含有前胡素的化妆品或药物组合物，以增强表皮角质形成细胞干细胞（KSC）的数量，并确保抗衰老。 构成：用于增殖表皮角化细胞干细胞的组合物含有前胡素作为活性成分。 前胡素是从当归奈加乙醇提取物或当归奈加超临界提取物得到的。 通过加入乙醇，搅拌和除去溶剂获得当归黑加诺乙醇提取物。 通过制备微粉末，使用硅胶柱色谱法纯化得到当归奈加超临界提取物。 化妆品组合物和用于抗衰老的药物组合物含有含有前胡素作为活性成分的组合物。
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Patent Agency Ranking
公开(公告)号：KR1020070106822A
公开(公告)日：2007-11-06
申请号：KR1020060039138
申请日：2006-05-01
Applicant: (주)아모레퍼시픽
IPC: A61K31/353 , A61P3/10
CPC classification number: A61K31/353
Abstract: A composition containing (-)catechin is provided to increase expression of adiponectin by inhibiting expression of a transition factor KLF7(Kruppel-like factor 7) and promotes sugar absorption in adipocytes of mammals, so that the composition is useful for preventing and treating diabetes mellitus, arteriosclerosis and obesity. A composition for preventing and treating diabetes mellitus, arteriosclerosis and obesity contains 0.01-30 wt.%, preferably 1-15 wt.% of (-)catechin represented by the formula(1), wherein the (-)catechin is isolated from green tea. The daily dosage of (-)catechin is 0.1-50 mg/kg, preferably 1-20 mg/kg and the expression of adiponectin in a mammal adipocyte is increased by treating an adipocyte with (-)catechin for 24 hours.
Abstract translation: 提供含有（ - ）儿茶素的组合物，通过抑制转录因子KLF7（Kruppel样因子7）的表达来增加脂联素的表达，并促进哺乳动物脂肪细胞中的糖吸收，使得该组合物可用于预防和治疗糖尿病 ，动脉硬化和肥胖。 用于预防和治疗糖尿病，动脉硬化和肥胖症的组合物含有0.01-30重量％，优选1-15重量％的由式（1）表示的（ - ）儿茶素，其中（ - ）儿茶素与绿色分离 茶。 （ - ）儿茶素的日剂量为0.1-50mg / kg，优选为1-20mg / kg，通过用（ - ）儿茶素处理脂肪细胞24小时，哺乳动物脂肪细胞中脂联素的表达增加。
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公开(公告)号：KR1020070072359A
公开(公告)日：2007-07-04
申请号：KR1020060119575
申请日：2006-11-30
Applicant: (주)아모레퍼시픽
IPC: A61K36/904 , A61K36/70 , A61P3/04
Abstract: A composition comprising a plant extract is provided to activate the TCA cycle by inducing the IDH3alpha(isocitrate dehydrogenase) gene promoter, thereby promoting the decomposition of lipid and preventing and treating obesity and hyperlipidemia. The composition comprises at least one plant extract selected from the group consisting of an extract of Belamcandae Rhizoma, an extract of Galium spurium, an extract of Persicaria hydropiper, an extract of Chrysanthemum zawadskii var. lucidum, an extract of Pinus koraiensis, and an extract of Cryptotaenia japonica. The extract is prepared by using a solvent selected from the group consisting of ethanol, methanol, butanol, ethylacetate, chloroform and hexane.
Abstract translation: 提供包含植物提取物的组合物以通过诱导IDH3α（异柠檬酸脱氢酶）基因启动子来激活TCA循环，从而促进脂质分解并预防和治疗肥胖症和高脂血症。 所述组合物包含至少一种植物提取物，所述植物提取物选自枸杞提取物，an an提取物，水an提取物，菊花提取物。 灵芝，红松提取物，枸杞提取物。 通过使用选自乙醇，甲醇，丁醇，乙酸乙酯，氯仿和己烷的溶剂制备提取物。
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公开(公告)号：KR101794750B1
公开(公告)日：2017-11-10
申请号：KR1020110094352
申请日：2011-09-20
Applicant: (주)아모레퍼시픽
IPC: A61K36/9066 , C12N5/0775 , A61P17/00
Abstract: 본발명은인간중간엽줄기세포의지방세포로의분화를촉진하는조성물에관한것으로, 보다상세하게는울금추출물을유효성분으로함유하여인간중간엽줄기세포를지방세포로분화하는것을촉진시킴으로써지방체 (Lipid droplet)를생성하여피부의볼륨과탄력을증진시키고주름을개선시키는조성물에관한것이다.
Abstract translation: 因此本发明涉及一种组合物用于促进人类的间充质干细胞的脂肪细胞的分化，由作为活性成分的促进人类干细胞的分化的间充质脂肪细胞，脂肪体（脂质含有更具体地，姜黄提取物 改善皮肤的容量和弹性并改善皱纹。
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