公开(公告)号：KR100817029B1

公开(公告)日：2008-04-18

申请号：KR1020070022720

申请日：2007-03-08

Applicant: 대한민국(농촌진흥청장)

Inventor： 강석진 ,  서국현 ,  허태영 ,  김현섭 ,  기광석 ,  이왕식

IPC: A23K1/00 ,  A23K1/16 ,  A23K1/175

CPC classification number: A23K40/30 ,  A23K20/10 ,  A23K20/20 ,  A23K50/00

Abstract: A method of manufacturing silver nanoparticles of a protective coating stable without decomposition in the stomach is provided to give silver nanoparticles having effects of causing no adverse effects when fed to a pig and poultry, increasing productivity and reducing the generation of odors in livestock facilities and capable of being well absorbed in the intestine and used as a feed additive. Silver nanoparticles stable without decomposition in the stomach are prepared by the steps of: immobilizing a silver nanoparticle colloidal solution and nutrients to a water insoluble carrier; mixing the fixed silver nanoparticle colloidal solution and a coating agent and stirring; and encapsulating the mixture. The silver nanoparticle colloidal solution has a particle size of 1 to 15nm and contains one or more polymeric stabilizers selected from the group consisting of polyvinylpyrrolidone, (1-vinyl pyrrolidone)-acrylic acid copolymer, polyoxyethylene stearate and (1-vinylpyrrolidone)-vinyl acetic acid copolymer. The carrier is selected from the group consisting of silica, cellulose, starch, zeolite, calcium carbonate, wheat red dog and corn flour. The coating agent is selected from the group consisting of a monovalent soap, divalent soap, hydrogenated vegetable oil and the like.

Abstract translation: 提供一种保护性涂层的银纳米颗粒在胃中不分解而稳定地制备的银纳米颗粒，以提供银纳米颗粒，其具有在喂给猪和家禽时不会产生不利影响的效果，提高生产力并减少牲畜设施中的气味产生和能力 在肠中被良好吸收并用作饲料添加剂。 通过以下步骤制备稳定而不分解在胃中的银纳米颗粒：将银纳米颗粒胶体溶液和营养物固定在水不溶性载体上; 将固定的银纳米颗粒胶体溶液和涂层剂混合并搅拌; 并封装混合物。 银纳米颗粒胶体溶液具有1至15nm的粒度，并且含有一种或多种选自聚乙烯吡咯烷酮，（1-乙烯基吡咯烷酮） - 丙烯酸共聚物，聚氧乙烯硬脂酸酯和（1-乙烯基吡咯烷酮） - 乙烯基乙酸酯 酸共聚物。 载体选自二氧化硅，纤维素，淀粉，沸石，碳酸钙，小麦红狗和玉米粉。 涂层剂选自单价皂，二价皂，氢化植物油等。