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公开(公告)号：KR1020100074874A
公开(公告)日：2010-07-02
申请号：KR1020080133421
申请日：2008-12-24
Applicant: 한국과학기술원
IPC: G01N15/05 , G01N33/49 , G01N33/53 , G01N33/555
Abstract: PURPOSE: A micro particle separating device and a method therefor are provided to achieve a high speed sample processing rate by using high speed fluid flow and to easily and rapidly process blood corpuscles and plasma separation which is a necessary step for a blood test. CONSTITUTION: A micro particle separating device(100) comprises a micro fluid injection part(110) wherein micro fluid including micro particles is injected into the micro fluid injection part, a first channel(120) which is connected with the micro fluid injection part and wherein the micro particles in the micro fluid are passed through, a second channel(130) wherein the height of the second channel is lower than the height of the first channel and which is formed in the side of the first channel side and filters the micro fluid in order not to includes micro particle, a micro particle discharge part(140) which is connected with the first channel and discharges the micro particles passing through the first channel, and a micro fluid discharge part(150) which is connected with the second channel and discharges the micro fluid passing through the second channel.
Abstract translation: 目的：提供微粒分离装置及其方法，以通过使用高速流体流动来实现高速样品处理速率，并且容易且快速地处理作为血液测试的必要步骤的血小板和血浆分离。 构造：微粒分离装置（100）包括微流体注入部分（110），其中包括微粒子的微流体注入到微流体注入部分中，与微流体注入部分连接的第一通道（120）和 其中微流体中的微粒通过，第二通道（130），其中第二通道的高度低于第一通道的高度，并且形成在第一通道侧的侧面，并且过滤微 流体，以不包括微粒子，与第一通道连接并排出通过第一通道的微粒子的微粒子排出部分（140）和与第二通道连接的微流体排出部分（150） 通道并排出通过第二通道的微流体。
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公开(公告)号：KR100944489B1
公开(公告)日：2010-03-03
申请号：KR1020080017720
申请日：2008-02-27
Applicant: 한국과학기술원
Abstract: 본 발명은 광 전도성(photoconductive) 물질로 구성된 저항의 전기 전도 여부를 광을 이용하여 제어함으로써 특정 위치에서만 전류에 의한 Joule 발열이 일어나도록 제어할 수 있는 미세 전열발생부와 이 미세 전열부에서 발생하는 열을 이용하여 유체에 떠 있는 입자(particle)나 액적(droplet)을 구동하는 미세유체 처리장치(apparatus for microfluidic processing)에 관한 것으로, 본 발명에 따른 미세유체 처리장치는,
광으로 전류의 흐름을 온 오프(on off)하며, 광 전도성 저항의 어레이(array; 배열)로 구성된 미세 전열발생부; 상기 미세 전열발생부에 광이 가해지는 위치와 가해지는 광의 패턴을 조절하는 광원부; 및, 상기 미세 전열발생부에서 발생한 열에 의해 유체 내에 대류를 유발하여 입자나 액적(droplet)을 이동시키는 입자구동부를 포함하는 것을 특징으로 한다.-
公开(公告)号：KR100931983B1
公开(公告)日：2009-12-15
申请号：KR1020080031592
申请日：2008-04-04
Applicant: 한국과학기술원
Abstract: 본 발명은 마이크로 채널 내부에 흐르는 유체가 와류를 형성하게 함으로서 주입된 서로 다른 유체가 와류를 통해 서로 혼합되는 미세유체 혼합 장치에 관한 것으로, 본 발명에 따른 미세유체 혼합 장치는,
적어도 하나 이상의 미세유체 주입부; 상기 미세유체 주입부와 연결된 제1 채널 구간과 상기 제1채널 구간의 유동 단면적보다 작은 유동 단면적을 갖는 제2 채널 구간을 구비한 미세유체 혼합부; 및, 상기 미세유체 혼합부와 연결된 미세유체 배출부를 포함하는 것을 특징으로 한다.Abstract translation: 目的：提供一种用于混合微流体的装置，以在通道内产生具有特定结构的高流速，用于产生涡流。 构成：一种用于混合微流体的设备包括微流体注射器（10），微流体混合器（20）和微流体释放器（40）。 至少准备一个微流体注射器。 微流体混合器包括具有横截面流动面积的第二通道部分。 第二通道中的最小横截面流动区域的直径是100μm。 微流体混合器以规则的间隔形成在用于混合微流体的设备的内壁上。 微流体排放器连接到微流体混合器。
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公开(公告)号：KR1020090105481A
公开(公告)日：2009-10-07
申请号：KR1020080030950
申请日：2008-04-02
IPC: G01N35/00
Abstract: PURPOSE: A device for discriminating between cancerous and normal cells is provided to be effectively used in cell discernment by using the difference between the bulge of normal cell with lots of scaffold protein and the bulge of cancer cell with small scaffold protein. CONSTITUTION: A device(10) for discriminating between cancerous and normal cells comprises a fluidic channel(20), a diaphragm(30), and a control channel(40). A flow channel(21) in which the fluid containing a cell on the surface of the fluidic channel. The diaphragm is laminated at the upper part of the fluidic channel. An inlet and an outlet are formed in the control channel to correspond to both ends of the fluidic channel.
Abstract translation: 目的：提供用于区分癌细胞和正常细胞的装置，以通过使用正常细胞的隆起与大量支架蛋白的差异和具有小支架蛋白的癌细胞的隆起来有效地用于细胞鉴别。 构成：用于区分癌细胞和正常细胞的装置（10）包括流体通道（20），隔膜（30）和控制通道（40）。 流动通道（21），其中在流体通道的表面上含有电池的流体。 膜片层压在流体通道的上部。 入口和出口形成在控制通道中以对应于流体通道的两端。
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公开(公告)号：KR1020090092062A
公开(公告)日：2009-08-31
申请号：KR1020080017341
申请日：2008-02-26
Applicant: 한국과학기술원
IPC: B01D35/00
CPC classification number: A61M1/0281 , A61M2202/0439
Abstract: A device for filtering microparticle is provided to filter specific particles effectively from micro fluid in which various size of particles are included, and to remove impurities with high efficiency without change of a flow of blood. A device for filtering microparticle includes the followings: an injection part(10) in which fluid including the microparticle is injected; a separation part(20) separating the microparticle which is included in the fluid injected to the injection part; a filtration part(45) formed to a part of channel connected to the separation part; and a crossing part(50) in which channels are crossed.
Abstract translation: 提供了一种过滤微粒的装置，用于有效地从包含各种尺寸的颗粒的微流体中过滤特定的颗粒，并且高效率地除去杂质而不改变血流。 用于过滤微粒的装置包括：其中注入包含微粒的流体的注射部分（10）; 分离部分（20），分离包含在注入到注射部分中的流体中的微粒; 形成在与分离部连接的通路的一部分的过滤部（45） 和交叉部分（50），其中通道被交叉。
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Patent Agency Ranking
公开(公告)号：KR1020090089650A
公开(公告)日：2009-08-24
申请号：KR1020080014936
申请日：2008-02-19
Applicant: 한국과학기술원
IPC: G01N35/00
Abstract: A fluid test apparatus is provided to reduce complex pretreatment process of blood and examination time and quickly determine which blood is suitable for a patient. A fluid test apparatus comprises: two more injection parts (10) which injects fluid containing micro particle; a separation part (30) which separates particles in the fluid; a crossing part (50) having flow path in order for fluid or micro particle to cross; and a reaction part (70) in which crossed fluid or micro particle interacts.
Abstract translation: 提供流体测试装置以减少复杂的血液预处理过程和检查时间，并快速确定哪种血液适合患者。 流体测试装置包括：两个注射部分（10），其注入含有微粒子的流体; 分离部分（30），其分离流体中的颗粒; 具有用于流体或微粒交叉的流路的交叉部分（50）; 和反应部分（70），其中交叉流体或微粒子相互作用。
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公开(公告)号：KR1020090088085A
公开(公告)日：2009-08-19
申请号：KR1020080013432
申请日：2008-02-14
Applicant: 한국과학기술원
Abstract: A lab-on-a-chip system using a microvalve with photothermal effect is provided to control fluid which flows in and out even in the environment in which dose not have pump or complex electronic circuit. A lab-on-a-chip system in which a microvalve is formed through photothermal effect comprises: a micro channel (1) in which fluid moves; a control chamber (2) in which medium is expanded or contracted and which is formed on the micro channel; and an elastic membrane (3) which makes the micro channel open and close by elasticity change.
Abstract translation: 提供了使用具有光热效应的微型阀的片上实验室系统来控制甚至在没有泵或复杂电子电路的环境中流入和流出的流体。 其中通过光热效应形成微型阀的芯片实验室系统包括：流体移动的微通道（1）; 其中介质膨胀或收缩并且形成在微通道上的控制室（2）; 以及通过弹性变化使微通道开闭的弹性膜（3）。
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公开(公告)号：KR100907213B1
公开(公告)日：2009-07-10
申请号：KR1020070126893
申请日：2007-12-07
Applicant: 한국과학기술원
IPC: G01N35/00
CPC classification number: B03C1/32 , B01L3/502761 , B03C1/288 , B03C2201/18 , Y10T436/25375
Abstract: 본 발명은 등자기영동 기술을 이용하여 미세입자의 자기 자화율을 측정하여 미세입자를 분리하는 방법에 관한 것이다. 본 발명의 등자기영동기술을 이용한 미세입자 분리 장치는 서로 다른 자기 자화율을 갖는 유체와 측정 대상인 미세입자를 미세유체 채널에 주입하여 유체의 자화율 구배를 형성시키고, 채널에 강한 자기장을 인가하여 주입된 미세입자의 거동을 제어함으로써 각 미세입자들이 자기와 같은 자화율을 갖는 유체가 있는 위치로 이동시킨다. 본 발명에 의할 때에 근소한 자화율 차이를 갖는 미세입자의 자화율을 측정하여 분리할 수 있다.
등자기영동, 자기 자화율, 미세유체소자, 랩온어칩-
公开(公告)号：KR100849928B1
公开(公告)日：2008-08-04
申请号：KR1020070017774
申请日：2007-02-22
Applicant: 한국과학기술원
IPC: H01L31/10
CPC classification number: H01L31/08 , H01L31/0376 , Y02E10/548
Abstract: A three-dimensional optoelectronic tweezers system and a microfluidic manipulation method thereof are provided to increase a throughput by migrating a fluid with low energy. A projection unit includes a light source(10) for irradiating light to a particular region. Two light-transmitting layers(31,33) apply a voltage to the particular region while the projection unit irradiates the light to the particular region. A fine fluid path(40) is positioned between the light-transmitting layers to migrate drops of fine fluid or solid particles of the fine fluid. The projection unit includes the light source and a brightness pattern forming unit for controlling brightness by using an arbitrary pattern by irradiating the light.
Abstract translation: 提供三维光电镊子系统及其微流体操纵方法，以通过以低能量迁移流体来增加产量。 投影单元包括用于将光照射到特定区域的光源（10）。 两个透光层（31,33）在特定区域施加电压，而投影单元将光照射到特定区域。 精细流体路径（40）位于透光层之间，以移动精细流体的液滴或精细流体的固体颗粒。 投影单元包括光源和用于通过照射光来使用任意图案来控制亮度的亮度图案形成单元。
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公开(公告)号：KR100841021B1
公开(公告)日：2008-06-24
申请号：KR1020070048690
申请日：2007-05-18
Applicant: 한국과학기술원
IPC: G02F1/167
CPC classification number: G02F1/167 , G02F2001/1678 , G02F2001/294 , G09G3/344
Abstract: An apparatus and a method for driving micro-particles using a flat panel display and a lens are provided to remove dispersion caused by diffraction of light by condensing and applying an image irradiated from the flat panel display by using the lens and form light, applied through an arbitrary pattern, as a clear driving image with high resolution on a photoconductive layer. A flat panel display(10) irradiates light. A lens(20) condenses light outputted from the flat panel display. A photoconductive layer(30) applies voltage to an area where the light is condensed by the lens. A ground layer(40) forms an electric field in the photoconductive layer. A micro-fluid channel(50) moves solid particles within micro-fluid through the voltage applied to the condensed area of the photoconductive layer.
Abstract translation: 提供了使用平板显示器和透镜驱动微粒子的装置和方法，以通过使用透镜冷凝并施加从平板显示器照射的图像来形成光，从而除去由光的衍射引起的色散并形成光 作为在光电导层上具有高分辨率的清晰驱动图像的任意图案。 平板显示器（10）照射光。 透镜（20）会聚从平板显示器输出的光。 光电导层（30）将电压施加到透镜所聚光的区域上。 接地层（40）在光电导层中形成电场。 微流体通道（50）通过施加到光电导层的冷凝区域的电压在微流体中移动固体颗粒。
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