公开(公告)号：AU6224001A

公开(公告)日：2001-11-26

申请号：AU6224001

申请日：2001-04-28

Applicant: DEGUSSA

Inventor： KRILL STEFFEN ,  HUTHMACHER KLAUS ,  PERRIN SYLVAIN

IPC: C07C45/28 ,  C07B61/00 ,  C07C45/00 ,  C07C45/51 ,  C07C45/58 ,  C07C45/64 ,  C07C49/403 ,  C07D301/14

Abstract: Process for the production of 2,2,6-trimethylcyclohexane-1,4-dione by epoxidation of beta-isophorone with organic percarboxylic acids at a water content below 5 wt.-% and subsequent isomerization of the mixture of beta-isophorone epoxide and hydroxyisophorone.

公开(公告)号：DE10024264A1

公开(公告)日：2001-11-22

申请号：DE10024264

申请日：2000-05-17

Applicant: DEGUSSA

Inventor： KRILL STEFFEN ,  HUTHMACHER KLAUS ,  PERRIN SYLVAIN

IPC: C07B61/00 ,  C07C45/00 ,  C07C45/51 ,  C07C45/58 ,  C07C45/64 ,  C07C49/403 ,  C07C45/28 ,  C07C45/27 ,  C07C45/67 ,  C07D301/16 ,  C07D303/00

Abstract: Production of dihydroketoisophorone comprises reaction of beta -isophorone with an organic percarboxylic acid. The mixture of initially-formed beta -isophorone epoxide and isomeric 4-hydroxyisophorone is isomerized in situ either thermally or in presence of an acid catalyst or a salt. Production of dihydroketoisophorone (2,2,6-trimethylcyclohexane-1,4-dione) (I) comprises reaction of beta -isophorone (3,5,5-trimethylcyclohex-3-en-1-one) (II) with an organic percarboxylic acid in the form of a non-aqueous solution, at 0-200 deg C in an inert organic solvent. The per-acid is formed in a separate equilibrium reaction and absorbed or extracted with the oxidation solvent. The mixture of initially-formed beta -isophorone epoxide (III) and isomeric 4-hydroxyisophorone (HIP) (IV) is isomerized in situ either thermally or in presence of an acid catalyst or a salt.

公开(公告)号：DE10011405A1

公开(公告)日：2001-09-13

申请号：DE10011405

申请日：2000-03-09

Applicant: DEGUSSA

Inventor： MAASEN RALF ,  KRILL STEFFEN ,  HUTHMACHER KLAUS

IPC: C07B61/00 ,  C07C46/08 ,  C07C50/02 ,  C07C50/04

Abstract: Production of 2,3,5-trimethyl-p-benzoquinone comprises the oxidation of 2,3,5- or 2,3,6-trimethylphenol with oxygen or an oxygen-containing gas in a mixture of water and an 8-11C neocarboxylic acid and in the presence of a catalyst containing one or more copper(II) salts at 50-100 degrees C.

公开(公告)号：DE10011403A1

公开(公告)日：2001-09-13

申请号：DE10011403

申请日：2000-03-09

Applicant: DEGUSSA

Inventor： KRILL STEFFEN ,  KRETZ STEPHAN ,  HUTHMACHER KLAUS

IPC: B01J27/138 ,  B01J38/00 ,  C07B61/00 ,  C07D311/72

Abstract: Production of alpha -tocopherol acetate in a recirculating process involves condensation of trimethylhydroquinone and isophytol in presence of a catalyst system comprising zinc halide and an aqueous protonic acid and optionally an elemental metal in a polar solvent/water mixture and subsequent acylation of the resultant alpha -tocopherol. Production of alpha -tocopherol acetate (I) in a recirculating process involves condensation of trimethylhydroquinone and isophytol in presence of a catalyst (II) system comprising zinc halide (IIa) and an aqueous protonic acid (IIb) and optionally an elemental metal in a polar solvent/water mixture extractable or miscible with water. The alpha -tocopherol initially obtained is separated from the aqueous catalyst phase and esterified with an acylating agent. The solution of (II) obtained after working up by aqueous extraction is regenerated and the solution containing acetic acid is returned to the reaction. (II) is concentrated and reintroduced into the reaction in liquid form.

公开(公告)号：SK15312000A3

公开(公告)日：2001-09-11

申请号：SK15312000

申请日：2000-10-13

Applicant: DEGUSSA

Inventor： WEIGEL HORST ,  KRILL STEFFEN ,  HASSELBACH HANS JOACHIM DR ,  HUTHMACHER KLAUS

IPC: C07C67/00 ,  C07D311/72 ,  C07C67/52

公开(公告)号：CA2323301A1

公开(公告)日：2001-04-15

申请号：CA2323301

申请日：2000-10-13

Applicant: DEGUSSA

Inventor： HUBNER FRANK ,  DRAPAL BERND ,  PETER RAINER ,  SHI NONGYUAN ,  KRILL STEFFEN ,  HUTHMACHER KLAUS ,  WECKBECKER CHRISTOPH

IPC: B01J31/02 ,  C07B61/00 ,  C07C45/51 ,  C07C45/62 ,  C07C45/69 ,  C07C49/04 ,  C07C49/203 ,  C07C45/71

Abstract: Process for the preparation of unsaturated 4,5-allene ketones by reaction of tertiary propargyl alcohols with alkenyl alkyl ethers or ketals in the presence of aliphatic sulfonic acids or sulfonic acid salts.

公开(公告)号：BR9805589A

公开(公告)日：2000-04-11

申请号：BR9805589

申请日：1998-12-17

Applicant: DEGUSSA

Inventor： KRILL STEFFEN ,  HUEBNER FRANK ,  HAHN RAINER ,  WEIGEL HORST ,  HUTHMACHER KLAUS

IPC: C07B61/00 ,  C07D311/72 ,  C07D311/74

Abstract: Preparation of alpha -tocopherol ester compounds (I) involves reacting a hydroquinone ester (II) with an allyl alcohol derivative (III) in presence of a zinc halide and an acid. Preparation of alpha -tocopherol esters (or derivatives or homologues) of formula (I) involves reacting a hydroquinone mono- (sic) or diester of formula (II) with an allyl alcohol derivative of formula (III) in presence of a zinc halide and a protonic acid at 25-100 degrees C. R1, R2 = optionally unsaturated 1-20C alkyl; R3-R5 = H or 1-3C alkyl; n = 0-5; Q = -C(Me)=CH-CH2L or -C(Me)(L')-CH=CH2; L = OH, halo, acetoxy, MeSO2O, EtSO2O, PhSO2O or toluenesulfonyl; L' = OH, halo or acetoxy.

公开(公告)号：CA2281293A1

公开(公告)日：2000-03-01

申请号：CA2281293

申请日：1999-08-31

Applicant: DEGUSSA

Inventor： HEINZ DIETER ,  HOELDERICH WOLFGANG ,  KRILL STEFFEN ,  BOECK WOLFGANG ,  HUTHMACHER KLAUS

IPC: C07D213/79 ,  C07D213/80 ,  C07D213/803 ,  C07D213/807

Abstract: The invention relates to an improved process for the preparation of nicotinic acid by the direct oxidation of .beta.-picoline in the gas phase, wherein water and .beta.-picoline are fed separately to the catalyst bed and the catalyst is based on a titanium dioxide support which has been prepared by the sulfate method and has a high specific surface area and a vanadium oxide content of from 5 to 50 %.

公开(公告)号：CA2271518A1

公开(公告)日：1999-11-13

申请号：CA2271518

申请日：1999-05-12

Applicant: DEGUSSA

Inventor： SCHMITT HERMANN ,  HAHN RAINER ,  HUTHMACHER KLAUS ,  KRETZ STEPHAN ,  HASSELBACH HANS-JOACHIM ,  KRILL STEFFEN

IPC: B01J23/04 ,  B01J27/055 ,  B01J27/232 ,  B01J27/236 ,  B01J31/02 ,  B01J31/04 ,  B01J31/12 ,  B01J31/14 ,  C07B61/00 ,  C07C45/67 ,  C07C45/82 ,  C07C49/603

Abstract: 1. Process for the preparation of 3,5,5-trimethylcyclohexa-3-en-1-one (.beta.-isophorone). 2.1 The invention relates to a process for the preparation of the title compound by isomerisation of 3,5,5-trimethylcyclohexa-2-en-1-one (.alpha.-isophorone) in the liquid phase in the presence of a salt-like or organometallic catalyst. 2.2 Through the use of catalytic quantities of alkali-metal salts or alkaline-earth salts and of their organometallic compounds, and without addition of a further auxiliary substance, the space-time yield in the preparation of .beta.-isophorone is successfully raised to a level suitable for industrial application by means of a reasonably-priced, generally available catalyst and at the same time a known per se process is distinctly improved. 2.3 .beta.-Isophorone is particularly suitable as an intermediate product for the preparation of ketoisophorone.

公开(公告)号：CA2261404A1

公开(公告)日：1999-08-12

申请号：CA2261404

申请日：1999-02-11

Applicant: DEGUSSA

Inventor： WEIGEL HORST ,  KRILL STEFFEN ,  HASSELBACH HANS JOACHIM ,  HUTHMACHER KLAUS ,  SHI NONGYUAN ,  HUEBNER FRANK

IPC: B01J21/02 ,  B01J27/02 ,  B01J27/06 ,  B01J31/02 ,  C07B61/00 ,  C07C37/01 ,  C07C37/06 ,  C07C39/08 ,  C07C67/00 ,  C07C69/017 ,  C07C69/16 ,  C07C37/07 ,  C07C69/28 ,  C07C67/46

Abstract: This invention relates to an improved process for the production of 2,3,5-trimethylhydroquinone by rearrangement of 4-oxoisophorone (ketoisophorone, 3,5,5-trimethyl-2-cyclohexen-1,4-dione) to yield a trimethylhydroquinone diester and the subsequent saponification thereof. Trimethylhydroquinone is in turn an important starting material for the production of vitamin E.